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1,815,519 Results Found

  • Article
  • Open Access

Composite Reinforced Expanded Clay and Basalt Fiber Concrete for Floating Platforms

  • Alexey N. Beskopylny,
  • Sergey A. Stel′makh,
  • Evgenii M. Shcherban′,
  • Diana M. Shakhalieva,
  • Andrei Chernil′nik,
  • Alexandr Evtushenko,
  • Maksim Nikolenko and
  • Yasin Onuralp Özkılıç
J. Compos. Sci.2025, 9(12), 697;https://doi.org/10.3390/jcs9120697 
(registering DOI)

13 December 2025

Currently, in hydrotechnical engineering, such as oil and gas platform construction, floating docks, and other floating structures, the need to develop new lightweight composite building materials is becoming an important problem. Expanded clay concr...

  • Article
  • Open Access
Electronics2025, 14(24), 4908;https://doi.org/10.3390/electronics14244908 
(registering DOI)

13 December 2025

In hardware/software (HW/SW) partitioning, the most commonly established objectives are execution time, power consumption, and hardware area. Surprisingly, memory usage, a critical resource in embedded systems, has received limited attention as a pri...

  • Article
  • Open Access
Molecules2025, 30(24), 4770;https://doi.org/10.3390/molecules30244770 
(registering DOI)

13 December 2025

A multi-stage TG-DSC approach consisting of five heating/holding and five cooling/holding stages within one experiment in the temperature range 20–320 °C was applied to investigate the dehydration/hydration processes in K+, Na+, Ca2+, and M...

  • Article
  • Open Access
Biomedicines2025, 13(12), 3080;https://doi.org/10.3390/biomedicines13123080 
(registering DOI)

13 December 2025

Background/Objectives: Neuroinflammation is a leading factor in secondary brain damage following a traumatic brain injury (TBI). Existing therapeutic approaches have limited efficacy against neuroinflammation. The bone marrow, the primary hematopoiet...

  • Article
  • Open Access

Association Between Postoperative Pain Intensity and Delirium in Cardiac and Neurosurgical Patients: A Retrospective Pilot Study

  • Mateusz Szczupak,
  • Jacek Kobak,
  • Jakub Wiśniewski,
  • Jolanta Wierzchowska and
  • Sabina Krupa-Nurcek
J. Clin. Med.2025, 14(24), 8840;https://doi.org/10.3390/jcm14248840 
(registering DOI)

13 December 2025

Background/Objective: Postoperative pain and delirium are frequent and clinically relevant complications in patients undergoing major cardiac or neurosurgical procedures. The interaction between these conditions remains insufficiently characterized,...

  • Article
  • Open Access
Buildings2025, 15(24), 4514;https://doi.org/10.3390/buildings15244514 
(registering DOI)

13 December 2025

With the increasing functional and geometric complexity of modern steel buildings, irregular-shaped beam-to-column joints are becoming common in engineering practice. However, their seismic behavior remains insufficiently understood, particularly for...

  • Review
  • Open Access

From Gynecological Endocrine Disorders to Cardiovascular Risk: Insights from Rat Models

  • Csanád Endre Lőrincz,
  • Zoltán Virág,
  • András Nagy,
  • Viktória Kiss,
  • Ákos Tóbiás,
  • Denise Börzsei,
  • Csaba Varga and
  • Renáta Szabó
Biomedicines2025, 13(12), 3081;https://doi.org/10.3390/biomedicines13123081 
(registering DOI)

13 December 2025

Gynecological endocrine disorders, including polycystic ovary syndrome (PCOS), endometriosis as well as primary ovarian insufficiency (POI)/premature ovarian failure (POF), significantly impact women’s reproductive health and overall well-being...

  • Article
  • Open Access
Plants2025, 14(24), 3807;https://doi.org/10.3390/plants14243807 
(registering DOI)

13 December 2025

The present study investigated the effects of copper oxide nanoparticles (CuO NPs) at concentrations of 0, 5, 10, 20, and 40 mg/L on micropropagation and the accumulation of lipophilic metabolites in Ajuga multiflora, a medicinally valuable ornamenta...

  • Case Report
  • Open Access

Malignant Syphilis in an Immunocompetent Patient: A Case Report and Review of the Literature

  • Chiara Vincenza Mazzola,
  • Eleonora Bono,
  • Ilenia Giacchino,
  • Cinzia Calà,
  • Luca Pipitò and
  • Antonio Cascio
J. Clin. Med.2025, 14(24), 8839;https://doi.org/10.3390/jcm14248839 
(registering DOI)

13 December 2025

Background: Syphilis can present with diverse clinical manifestations, earning the name “great imitator.” Malignant syphilis (MS) is a rare, severe form of secondary syphilis, typically reported in immunocompromised patients, particularly...

  • Article
  • Open Access
Drones2025, 9(12), 859;https://doi.org/10.3390/drones9120859 
(registering DOI)

13 December 2025

Unmanned Aerial Vehicles (UAVs) are playing an increasingly crucial role in large-scale Wireless Sensor Networks (WSNs) due to their high mobility and flexible deployment capabilities. To enhance network sustainability and profitability, this paper p...

  • Article
  • Open Access

Maternal Serum Ferritin Levels in Third Trimester and Risk of Small for Gestational Age in Northern Thailand: Implications for Management in Pregnancy

  • Pak Thaichana,
  • Ampica Mangklabruks,
  • Amaraporn Rerkasem,
  • Antika Wongthanee,
  • Suthathip Wongsrithep and
  • Kittipan Rerkasem
Nutrients2025, 17(24), 3911;https://doi.org/10.3390/nu17243911 
(registering DOI)

13 December 2025

Background: Iron deficiency anemia is a recognized pregnancy risk, but excessive iron may also have adverse effects. Few studies, particularly in Asian populations, have examined elevated maternal ferritin in relation to birth outcomes. Objectives: T...

  • Article
  • Open Access
Remote Sens.2025, 17(24), 4027;https://doi.org/10.3390/rs17244027 
(registering DOI)

13 December 2025

Greenland, home to the largest ice sheet in the Northern Hemisphere, provides a crucial digital elevation model (DEM) for understanding polar climate evolution and valuable data for global climate change research. Based on ICESat-2 laser altimetry da...

  • Article
  • Open Access
Heritage2025, 8(12), 535;https://doi.org/10.3390/heritage8120535 
(registering DOI)

13 December 2025

In the context of a study on selected fragments of ancient architecture belonging to a collection of the archaeological museum “Luigi Bernabò Brea” in Lipari (Aeolian Islands, Messina, Italy), we analysed, using the non-destructive...

  • Article
  • Open Access
Appl. Sci.2025, 15(24), 13132;https://doi.org/10.3390/app152413132 
(registering DOI)

13 December 2025

(1) Background: The midsole hardness (i.e., cushioning) of running shoes has received significant attention as a crucial element influencing both performance and injury prevention. This research aimed to examine how variations in midsole hardness aff...

  • Article
  • Open Access

Mineralogical and Geochemical Insights into Formation of the Muji Carbonic Springs, NW China

  • Li Zhang,
  • Yuxin Guo,
  • Guodong Zheng,
  • Yuanyuan Shao,
  • Alireza K. Somarin,
  • Vasilii Lavrushin and
  • Xiangxian Ma
Minerals2025, 15(12), 1302;https://doi.org/10.3390/min15121302 
(registering DOI)

13 December 2025

The Muji carbonic springs on the northeastern margin of the Pamir Plateau provide a natural window into tectonically controlled CO2 degassing within a continental collision zone. Through mineralogical and geochemical analyses, this study constrains t...

  • Article
  • Open Access

Conceptual Development of Terminal Airspace Integration Procedures of Large Uncrewed Aircraft Systems at Non-Towered Airports

  • Tim Felix Sievers,
  • Jordan Sakakeeny,
  • Husni Idris,
  • Niklas Peinecke,
  • Vishwanath Bulusu,
  • Enno Nagel and
  • Devin Jack
Drones2025, 9(12), 858;https://doi.org/10.3390/drones9120858 
(registering DOI)

13 December 2025

Uncrewed aircraft systems are expected to revitalize traffic activities at under-utilized airports. These airports are often located in uncontrolled airspace and do not have an operating control tower to provide separation services for approaching ai...

  • Article
  • Open Access

Optimizing Magnet Spacing to Enhance Power and Energy Density in Magnetically Levitated Electromagnetic Vibration Energy Harvesters

  • Madina Alimova,
  • Elvira Kadylbekkyzy,
  • Nurtay Albanbay,
  • Aigerim Issimova,
  • Rinat Ilesibekov and
  • Bekbolat Medetov
Micromachines2025, 16(12), 1404;https://doi.org/10.3390/mi16121404 
(registering DOI)

13 December 2025

In this study, we investigate a magnetically levitated electromagnetic vibration energy harvester (EMEH), in which a movable permanent magnet levitates between two fixed magnets with like poles facing the central magnet. We develop a nonlinear EMEH m...

  • Article
  • Open Access
Water2025, 17(24), 3534;https://doi.org/10.3390/w17243534 
(registering DOI)

13 December 2025

This study proposes a novel integrated framework that combines a Hippopotamus-Optimized Support Vector Regression (HO-SVR) prediction model with a Retrieval-Augmented Generation-enhanced Large Language Model (RAG-LLM)-based intelligent decision modul...

  • Article
  • Open Access

Characterization of the Biodeterioration Caused by the Fungus Serpula lacrymans in Lignocellulosic Materials of Building Envelopes

  • Rodrigo Espinoza Maldonado,
  • Carlos Rubio-Bellido,
  • Ariel Bobadilla-Moreno,
  • José Navarrete and
  • Paula Herrera
Buildings2025, 15(24), 4513;https://doi.org/10.3390/buildings15244513 
(registering DOI)

13 December 2025

Serpula lacrymans is considered the most aggressive and harmful brown-rot fungus for wooden buildings worldwide, and it has led to substantial economic losses due to the deterioration of wood and wooden-base structures. This study aims to connect the...

  • Article
  • Open Access

Effects and Mechanisms of Dufulin Toxicity on Zebrafish, Danio rerio

  • Shaoqian Jia,
  • Mengxue Li,
  • Guoqiang Yuan,
  • Long Wang and
  • Heng Chi
Toxics2025, 13(12), 1075;https://doi.org/10.3390/toxics13121075 
(registering DOI)

13 December 2025

Pesticide pollution has become a major global issue, primarily because of its ability to induce widespread toxicity. This research aimed to explore the toxicological effects of Dufulin on zebrafish, focusing on the underlying molecular mechanisms of...

  • Article
  • Open Access

The 3D World of Spheroids: Searching for an Optimal Method of Fabricating Pro-Reparative Cardiospheres

  • Yulia Goltseva,
  • Zoya Tsokolaeva,
  • Irina Iarushkina,
  • Irina Beloglazova,
  • Maria Boldyreva,
  • Elizaveta Ratner,
  • Yelena Parfyonova and
  • Konstantin Dergilev
Int. J. Mol. Sci.2025, 26(24), 12025;https://doi.org/10.3390/ijms262412025 
(registering DOI)

13 December 2025

Cardiospheres (CSs) are widely used to boost the pro-reparative potential of adult cardiac cells, mediated through their unique secretome profile. The original CS generation method relies on self-assembly of cardiac explant-derived cells (EDCs) on po...

  • Article
  • Open Access
Aerospace2025, 12(12), 1104;https://doi.org/10.3390/aerospace12121104 
(registering DOI)

13 December 2025

This study examines the distance that an airplane is able to fly on inclined trajectories at various angles when it starts at different altitudes. It clearly exhibits the dependence of the airplane’s performance, when it climbs or descends, on...

  • Article
  • Open Access
Energies2025, 18(24), 6539;https://doi.org/10.3390/en18246539 
(registering DOI)

13 December 2025

This paper develops a compact and scalable mathematical model of an AC circuit with an uncontrolled diode bridge rectifier, formulated using dimensionless variables. The model captures the joint influence of supply inductance, resistance, and load pa...

  • Article
  • Open Access
Healthcare2025, 13(24), 3280;https://doi.org/10.3390/healthcare13243280 
(registering DOI)

13 December 2025

Background/Objectives: Although upper extremity dexterity problems are frequently reported in people with Parkinson’s disease (PwPD), valid and reliable scales for assessing upper extremity function and dexterity are limited. The objective of t...

  • Article
  • Open Access
J. Funct. Morphol. Kinesiol.2025, 10(4), 479;https://doi.org/10.3390/jfmk10040479 
(registering DOI)

13 December 2025

Background: Motor competence (MC) is defined as the ability to perform a wide range of motor skills with proficiency and control. The present quasi-experimental study design examines the impact of two structured intervention programs on MC in childre...

  • Article
  • Open Access
Electronics2025, 14(24), 4907;https://doi.org/10.3390/electronics14244907 
(registering DOI)

13 December 2025

To meet the demand for online monitoring of acetylene (C2H2) in transformer oil, a high-sensitivity detection system based on photoacoustic spectroscopy (PAS) is presented. The system integrates custom-designed modules for signal acquisition, phase-s...

  • Article
  • Open Access

Unraveling the Diversity of Haemosporidians in Brazilian Non-Passerine Birds: Insights from Midwestern Brazil

  • Morgana Maira Hennig,
  • Luiz Gustavo Magalhães Alves,
  • Marcela Natacha Aparecida Rocha,
  • Victória Luiza de Barros Silva,
  • Brenda Madruga Rosa,
  • Rosa Helena dos Santos Ferraz,
  • Sandra Helena Ramiro Corrêa,
  • Érika Martins Braga and
  • Richard de Campos Pacheco
Pathogens2025, 14(12), 1286;https://doi.org/10.3390/pathogens14121286 
(registering DOI)

13 December 2025

Avian haemosporidians have been widely studied because they provide important insights into parasite distribution and diversity. However, most available data come from passerines, resulting in gaps regarding other bird groups, primarily due to the di...

  • Article
  • Open Access

Long-Term Safety and Efficacy of Partially Absorbable Transobturator Mid-Urethral Sling in Women Aged 65 Years and Older

  • Réka Fábián-Kovács,
  • Asnat Groutz,
  • Jonatan Neuman,
  • Menahem Neuman,
  • Yoav Baruch and
  • Ronen S. Gold
J. Clin. Med.2025, 14(24), 8838;https://doi.org/10.3390/jcm14248838 
(registering DOI)

13 December 2025

Objectives: To assess the long-term safety and efficacy of the Serasis® partially absorbable transobturator mid-urethral sling (MUS) in women aged ≥65 years compared to younger women. Methods: A retrospective comparative study of 375 consecuti...

  • Article
  • Open Access

Formation AgI and ZnI2 Nanocrystals in AgI-ZnI2-SiO2 Hybrid Powders

  • Anastasiia Averkina,
  • Igor Valtsifer,
  • Vladimir Strelnikov,
  • Natalia Kondrashova and
  • Viktor Valtsifer
Nanomaterials2025, 15(24), 1875;https://doi.org/10.3390/nano15241875 
(registering DOI)

13 December 2025

AgI and ZnI2 nanocrystals are key components for AgI-ZnI2-SiO2 hybrid powders (HPs), which could be potentially important for atmospheric artificial precipitation technology. HPs were created by the “Hydrothermal template cocondensation”...

  • Article
  • Open Access

Modeling the Spatial Impact of Short-Term Rentals on House Prices: The Case of Athens, Greece

  • Polixeni Iliopoulou,
  • Vassilios Krassanakis and
  • Kallis Kappelos
Urban Sci.2025, 9(12), 539;https://doi.org/10.3390/urbansci9120539 
(registering DOI)

13 December 2025

The purpose of this study is to explore the spatial impact of short-term rental activity on house prices in the city of Athens, Greece. It is well established that the increasing number of short-term rentals has a number of consequences on the functi...

  • Feature Paper
  • Review
  • Open Access

A Review of Direct Recycling Processes for Lithium-Ion Battery Cells

  • Michał Łach,
  • Agnieszka Przybek,
  • Piotr Duda and
  • Piotr Bielaczyc
Materials2025, 18(24), 5608;https://doi.org/10.3390/ma18245608 
(registering DOI)

13 December 2025

In recent years, circular economy principles have become a key paradigm in the design and evaluation of industrial processes, including recycling technologies. Direct recycling of used lithium-ion batteries is attracting particular attention, as it c...

  • Article
  • Open Access

Impact of Dietary Moringa oleifera Leaf Polysaccharide on Growth Performance and Antioxidant Status in Broiler Chickens

  • Hosameldeen Mohamed Husien,
  • WeiLong Peng,
  • Raza Mohai Ud Din,
  • Mudathir Yahia Abdulrahman,
  • Nada N. A. M. Hassanine,
  • Mohamed Osman Abdalrahem Essa,
  • Saber Y. Adam,
  • Hozifa S. Yousif,
  • Ahmed A. Saleh and
  • Mengzhi Wang
  • + 1 author
Vet. Sci.2025, 12(12), 1196;https://doi.org/10.3390/vetsci12121196 
(registering DOI)

13 December 2025

Moringa oleifera (MO) is a versatile non-traditional feed supplement rich in bioactive compounds. The objective of this study was to examine the effects of MO leaf (MOL) polysaccharide (MOLP) intake as a natural product on broiler chicken production...

  • Review
  • Open Access
Agronomy2025, 15(12), 2866;https://doi.org/10.3390/agronomy15122866 
(registering DOI)

13 December 2025

Drought, salinity, heavy metal contamination and temperature fluctuations are increasingly constraining crop production. Conventional agronomic and chemical approaches alone often fail to ensure stable yields under these abiotic stresses. Nanomateria...

  • Article
  • Open Access
Soc. Sci.2025, 14(12), 712;https://doi.org/10.3390/socsci14120712 
(registering DOI)

13 December 2025

A robust literature focused on social capital created in the family has emphasized the efficacy of parental involvement in child, adolescent, and young adult development. Social capital created with and derived from parents has strong and consistent...

  • Article
  • Open Access

Spirulina-Incorporated Biopolymer Films for Antioxidant Food Packaging

  • Monica Masako Nakamoto,
  • Josemar Gonçalves Oliveira-,
  • Marcelo Assis and
  • Anna Rafaela Cavalcante Braga
Processes2025, 13(12), 4037;https://doi.org/10.3390/pr13124037 
(registering DOI)

13 December 2025

Growing environmental concerns and the need for sustainable materials have accelerated the search for biodegradable alternatives to food packaging. Since nearly half of global plastic production is dedicated to food packaging, and less than 5% is rec...

  • Article
  • Open Access
Climate2025, 13(12), 250;https://doi.org/10.3390/cli13120250 
(registering DOI)

13 December 2025

The aim of this study is to quantify the impact of increased surface solar radiation on climate warming in Central Europe from 1915 to 2024 and to examine the relationship between CO2 air concentrations and emissions on a global scale with an empiric...

  • Article
  • Open Access

Relationship Between Heart Rate, Muscle, and Peripheral Oxygen Saturation During Dry Static Apnea

  • Dario Vrdoljak,
  • Colin D. Hubbard,
  • Geoff B. Coombs,
  • Andrew T. Lovering,
  • Ivan Drvis,
  • Nikola Foretic,
  • Joseph W. Duke and
  • Željko Dujić
Oxygen2025, 5(4), 27;https://doi.org/10.3390/oxygen5040027 
(registering DOI)

13 December 2025

Background: During an apnea, oxygen depletion occurs at all tissue levels, so apnea duration is influenced by the mammalian dive reflex, which includes a bradycardia resulting in reduced cardiac oxygen consumption. This study aimed to examine the rel...

  • Article
  • Open Access

Functional Characterization of Double-Bond Reductases in Dihydro-β-Ionone Biosynthesis in Cymbidium sinense

  • Xueqian Gao,
  • Xinyue Li,
  • Yunpeng Jia,
  • Meimei Huang,
  • Yuechong Yue,
  • Lan Wang,
  • Yanping Fan and
  • Yunyi Yu
Plants2025, 14(24), 3804;https://doi.org/10.3390/plants14243804 
(registering DOI)

13 December 2025

Cymbidium sinense is a highly valued ornamental orchid renowned for its strong floral fragrance. In this study, dihydro-β-ionone was identified as a major volatile compound in C. sinense ‘Qi Hei’. Its emission increased progressively...

  • Article
  • Open Access

Advancing Lateral Flow Detection in CRISPR/Cas12a Systems Through Rational Understanding and Design Strategies of Reporter Interactions

  • Irina V. Safenkova,
  • Maria V. Kamionskaya,
  • Dmitriy V. Sotnikov,
  • Sergey F. Biketov,
  • Anatoly V. Zherdev and
  • Boris B. Dzantiev
Biosensors2025, 15(12), 812;https://doi.org/10.3390/bios15120812 
(registering DOI)

13 December 2025

CRISPR/Cas12a systems coupled with lateral flow tests (LFTs) are a promising route to rapid, instrument-free nucleic acid diagnostics due to conversion target recognition into a simple visual readout via cleavage of dual-labeled single-stranded DNA r...

  • Systematic Review
  • Open Access
Sustainability2025, 17(24), 11186;https://doi.org/10.3390/su172411186 
(registering DOI)

13 December 2025

Coastal ecosystems are among the most biodiverse and economically valuable environments on Earth, yet they face escalating threats from climate change, development, and resource exploitation. Traditional conservation approaches have proven insufficie...

  • Article
  • Open Access

Cross-Species Insights into In Vitro Maturation Defects of the Oocyte and Identification of Crucial Regulators for Sheep Oocyte Maturation

  • Jian Cui,
  • Xiurong Zhao,
  • Jia Hao,
  • Xingyuan Liu,
  • Wenjing Wang,
  • Lixia He,
  • Yubing Wang,
  • Jinfu Rong,
  • Chunjuan Qiu and
  • Dayong Chen
  • + 4 authors
Antioxidants2025, 14(12), 1499;https://doi.org/10.3390/antiox14121499 
(registering DOI)

13 December 2025

The poor quality of oocytes matured in vitro seriously hinders the application in mammalian assisted reproductive technology (ART). Exploring the regulators and mechanisms influencing oocyte maturation is critical to improve the developmental compete...

  • Review
  • Open Access

The Neural Contributions to Reactive Balance Control: A Scoping Review of EEG, fNIRS, MRI, and PET Studies

  • Andrew S. Monaghan,
  • Taylor Takla,
  • Edward Ofori,
  • Daniel S. Peterson,
  • Wendy Wu,
  • Nora E. Fritz and
  • Jason K. Longhurst
Brain Sci.2025, 15(12), 1330;https://doi.org/10.3390/brainsci15121330 
(registering DOI)

13 December 2025

Background/Objectives: Rapid postural reactions are critical for preventing falls, yet the neural systems supporting these responses are not fully understood, particularly with respect to aging and neurological disorders. Understanding how the brain...

  • Article
  • Open Access
Hearts2025, 6(4), 33;https://doi.org/10.3390/hearts6040033 
(registering DOI)

13 December 2025

Background: In cardiology, vasoregulation is one of the most important targets of pharmacotherapy. SOMNOtouch™-NIBP (SOMNOomedics AG, Randersacker, Germany) is a cuffless device designed for continuous, non-invasive blood pressure measurements,...

  • Article
  • Open Access

Tourism Resilience and Adaptive Recovery in an Island’s Economy: Evidence from the Maldives

  • Krisanadej Jaroensutasinee,
  • Aishath Hussain,
  • Mullica Jaroensutasinee and
  • Elena B. Sparrow
Tour. Hosp.2025, 6(5), 282;https://doi.org/10.3390/tourhosp6050282 
(registering DOI)

13 December 2025

This study investigates the resilience dynamics of the Maldives’ tourism sector through a longitudinal analysis of tourist arrivals from six global regions (2008–2024), focusing on spatiotemporal behavioral shifts induced by external shoc...

  • Article
  • Open Access

Long-Term Performance of Natural Filtration Dams for Landfill Leachate Treatment

  • Andrey Ivantsov,
  • Mikhail Viskov,
  • Ruslan Kataev,
  • Nadezhda Ozhgibesova,
  • Zhanna Knyazeva and
  • Yanina Parshakova
Environments2025, 12(12), 489;https://doi.org/10.3390/environments12120489 
(registering DOI)

13 December 2025

The study evaluates the long-term environmental performance of natural filtration dams for leachate treatment at a municipal solid waste landfill. Field measurements of a system operating for 24 years, equipped with natural clay-loam filtration barri...

  • Proceeding Paper
  • Open Access

Synthesis and In Silico Studies of a Novel 1,4-Disubstituted-1,2,3-Triazole-1,3-Oxazole Hybrid System

  • Camila Garibay-Manríquez,
  • Ana L. Caldelas-Guerrero,
  • América A. Frías-López,
  • Luis Chacón-García,
  • Erik Díaz-Cervantes and
  • Carlos J. Cortés-García
Chem. Proc.2025, 18(1), 63;https://doi.org/10.3390/ecsoc-29-26701 
(registering DOI)

11 November 2025

In this work, we report an efficient synthetic strategy for accessing novel 1,4-disubstituted-1,2,3-triazole-1,3-oxazole hybrids. The synthesis involves a two-step, three-sequence approach: a multicomponent reaction, subsequent oxidation, and the Van...

  • Article
  • Open Access

Repurposing FDA-Approved Drugs as Hendra Virus RNA-Dependent RNA Polymerase Inhibitors: A Comprehensive Computational Drug Discovery Approach

  • Anjana C. Lalu,
  • Varun Thachan Kundil,
  • Bristow Ben Joseph,
  • Radul R. Dev,
  • Amritha Thaikkad,
  • Suhail Subair,
  • Rajesh Raju and
  • Abhithaj Jayanandan
Viruses2025, 17(12), 1613;https://doi.org/10.3390/v17121613 
(registering DOI)

13 December 2025

Hendra virus (HeV) is a highly pathogenic zoonotic paramyxovirus that poses a serious threat to human and equine health, yet no approved antivirals or vaccines currently exist. RNA-dependent RNA polymerase (RdRp) of Hendra virus represents a critical...

  • Article
  • Open Access

Colletotrichum scovillei and Prospective Biocontrol Agents Isolated from Asymptomatic Olive Trees

  • Kallimachos Nifakos,
  • Polina C. Tsalgatidou,
  • Athanasios Tsafouros,
  • Christina Angeli,
  • Epaminondas Kartsonas,
  • Costas Delis,
  • Ioannis Charalampopoulos,
  • Anastasia Venieraki and
  • Panagiotis Katinakis
Microorganisms2025, 13(12), 2838;https://doi.org/10.3390/microorganisms13122838 
(registering DOI)

13 December 2025

Olive anthracnose is a major disease worldwide; although once chiefly attributed to Colletotrichum acutatum, it is now clear that the predominant pathogen varies among regions. In this study, we identified Colletotrichum scovillei for the first time...

  • Article
  • Open Access
Int. J. Mol. Sci.2025, 26(24), 12022;https://doi.org/10.3390/ijms262412022 
(registering DOI)

13 December 2025

Colorectal cancer (CRC) incidence is a significant cancer globally, and radiotherapy resistance is a serious problem. Cucurbitacin D (CBD), extracted from many plants such as the tubers of Trichosanthes kirilowii and the fruits of Ecballium elaterium...

  • Article
  • Open Access
Genes2025, 16(12), 1492;https://doi.org/10.3390/genes16121492 
(registering DOI)

13 December 2025

Background/objectives: Tropoelastin is a highly hydrophobic extracellular matrix protein responsible for the extensibility and elastic recoil of various organs. The Windkessel effect in blood vessels dampens pressure variations during the cardiac cyc...

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