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Owner-led self-medication for companion animals is a growing global practice; however, empirical data from Japan remain limited. Framing medication safety within a One Health perspective, this study aimed to characterize Japanese pet owners’ use of over-the-counter (OTC) drugs and identify possibilities for pharmacists to support rational self-medication. A cross-sectional 13-item online survey was administered to 500 owners in Japan between 30 May and 2 June 2025. Data on owner demographics, willingness to consult pharmacists, veterinary visit behavior, and OTC purchasing practices were summarized. Many owners were receptive to pharmacy support; 65% wished to consult a pharmacist, and 6.8% had already done so. Overall, 15.2% reported using OTCs drugs, primarily for treatment or prevention and prioritized perceived effectiveness and safety when selecting products. Some owners managed mild pet illnesses at home, citing perceived mildness and cost as reasons for not visiting a veterinary clinic. There is an unmet demand for accessible expert counseling at the point of purchase. Leveraging community pharmacies linked with pet specialty pharmacies as first-contact hubs could promote appropriate self-medication; doing so would require veterinary-specific training, establishing a formal credential for veterinary pharmacists, and defining pharmacist–veterinarian communication to ensure safe and effective use.

2 November 2025

Pet owners’ willingness to consult pharmacists about pets. (a) Pet owners’ willingness to consult pharmacists regarding pet medications (N = 500). (b) Specific topics consulted about among respondents who had already consulted pharmacists (N = 34). (c) Specific topics of interest among respondents who expressed a willingness to consult pharmacists (N = 324).

Fear, anxiety, and stress (FAS) in canine patients is a growing concern for the veterinary industry. FAS affects the health of the patient while also increasing the risk to veterinary staff. Studies show that many veterinarians do not feel confident in managing behavioural issues like FAS, making engaging effectively with clients more difficult. Pre-visit pharmaceuticals (PVPs) can be an important tool in mitigating the effects of FAS; however, conclusive research is lacking on the efficacy of many of the medications and combinations currently used for this purpose. A comprehensive literature search was conducted in multiple databases. The most current research available on medications identified as widely used for treating FAS, and available for use in New Zealand, has been reviewed and discussed. Combinations selected for inclusion were the ‘chill protocol’ of acepromazine, gabapentin, and melatonin. Single agents included are clonidine, dexmedetomidine, gabapentin, and trazodone. Research into the use of the ‘chill protocol’ suggests this may be a combination particularly useful in highly stressed and aggressive dogs; however, additional studies need to be conducted to strengthen the evidence for its use. A multimodal approach has been identified as being desirable when addressing FAS in a clinical setting, with less evidence to support the use of single-agent medications in mitigating problematic behaviours.

27 October 2025

  • Correction
  • Open Access

In the original publication [...]

15 October 2025

Histopathological Study of Canine Skin Hemangiomas and Hemangiosarcomas in Uruguay

  • Belén Varela,
  • Camila Larrañaga and
  • Victoria Yozzi
  • + 2 authors

We performed an histological study on all cases of canine skin hemangiomas and hemangiosarcomas that were examined between 2018 and 2020. Of the 446 dogs with skin tumors examined, 25 were diagnosed with hemangiomas and 24 were diagnosed with hemangiosarcomas. Mixed-breed dogs were the most commonly affected by both tumors. The average ages of the dogs who were diagnosed with hemangiomas and hemangiosarcomas were 8.70 and 8.36 years, respectively, with the mean age for hemangiosarcomas being slightly higher; however, this difference was not statistically significant. Both types of tumors were more common in the trunk and limbs. Sex differences in tumor frequency were not detected in dogs with hemangiomas or hemangiosarcomas. Histologically, the mixed capillary and cavernous type was the most common in cases of hemangiomas, and the mixed capillary, cavernous, and solid type and the mixed cavernous and solid type were more common in hemangiosarcoma cases compared with the other types. In addition, epithelioid hemangiosarcomas were frequently detected.

15 October 2025

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Pets - ISSN 2813-9372