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Sci

Sci is an international, peer-reviewed, open access journal on all research fields published monthly online by MDPI.

All Articles (488)

Background and aim: Artificial intelligence (AI) is gaining increasing relevance in orthopaedic surgery, particularly in prosthetic surgery, due to its ability to support preoperative planning through advanced imaging analysis, implant size prediction, and outcome forecasting. However, recent literature shows considerable variability in employed models, evaluated outcomes, and clinical applicability. The objective of this scoping review is to map AI applications in preoperative planning for orthopaedic arthroplasties and to assess their impact on radiographic and clinical outcomes, also discussing key ethical and medicolegal implications within both Italian and international contexts. Materials and methods: A literature review was conducted following scoping review methodology. The bibliographic search (10 September 2025) was performed in PubMed and Scopus using the query “preoperative planning WITH artificial intelligence AND prosthesis orthopaedic surgery AND outcomes”, restricted to the years 2020–2025, English-language studies, and research focused specifically on real-world AI techniques applied to preoperative planning in prosthetic surgery, reporting radiographic and/or clinical outcomes related to planning. Exclusion criteria included intra/postoperative studies, non-orthopaedic applications, robotic surgery, studies lacking clinical outcomes, case reports, and articles without full-text availability. After PRISMA screening and selection, 42 primary studies were included. Results: Of the 42 studies included, 20 focused on the hip, 19 on the knee, and 3 on the shoulder. Available evidence indicates that AI may improve templating accuracy and prosthetic component positioning, with more robust results in hip and knee arthroplasty, while applications in shoulder arthroplasty remain emerging. Nonetheless, important methodological limitations persist, including algorithm heterogeneity. Discussion: Overall, the findings suggest a promising role for AI in preoperative planning; however, the heterogeneity and variable quality of the evidence call for caution in interpretation and highlight the need for more rigorous prospective research. These considerations also carry relevant medicolegal implications, as the reliability and standardisation of AI-based tools represent essential prerequisites for their safe and conscious integration within diverse regulatory frameworks. Conclusions: AI appears to be a promising tool in the preoperative planning of orthopaedic arthroplasties, although further clinical validation and methodological standardisation are required. The evidence gathered also provides a useful foundation for addressing the associated medicolegal and regulatory implications, particularly in light of evolving Italian and European regulations and their differences from U.S. models.

29 January 2026

PRISMA flowchart.

Arsenic (As) accumulation in rice (Oryza sativa L.) is considered a major environmental and food safety concern, particularly in flooded agroecosystems where reducing conditions mobilize As from soils. Portugal is one of Europe’s rice producers, especially in the Tejo, Almansor, and Sorraia valleys. As such, this study evaluates As pathways across 5000 ha of rice fields in the Tagus, Sorraia, and Almansor alluvial plains by combining soil, water, and plant analyses with a geostatistical approach. The soils exhibited consistently elevated As concentrations (mean of 18.9 mg/kg), exceeding national reference values for agricultural soils (11 mg/kg) and forming a marked east–west gradient with the highest levels in the Tagus alluvium. Geochemical analysis showed that As is strongly correlated with Fe (r = 0.686), indicating an influence of Fe-oxyhydroxides under oxidizing conditions. The irrigation waters showed low As (mean of 2.84 μg/L for surface water and 3.51 μg/L for groundwater) and predominantly low sodicity facies, suggesting that irrigation water is not the main contamination vector. In rice plants, As accumulation follows the characteristic organ hierarchy roots > stems/leaves > grains, with root concentrations reaching up to 518 mg/kg and accumulating progressively in the maturity phase. Arsenic content in harvested rice grains was 266 μg/kg (with a maximum of 413.9 μg/kg), being close to EU maximum limits when considering typical inorganic As proportions, assuming 60 to 90% inorganic fraction. Together, the findings highlight that a combined approach is essential, and identify soil geochemistry (and not irrigation water) as the primary source of As transfer in those agroecosystems, due to the flooded conditions that trigger the reductive dissolution of Fe oxides, releasing As. Additionally, the results also identified the need for targeted monitoring in areas of elevated As content in soils and support future mitigation through As speciation analysis, cultivar selection, improved fertilization strategies, and water-management practices such as Alternate Wetting and Drying (AWD), to ensure the long-term food safety.

27 January 2026

Daily range of reported temperatures (A) and air humidity (B) during 2017 between April and November The graphic projection was carried out by R (software version 4.4.2) based on the data available on the Wunderground online platform (https://www.wunderground.com/, accessed on 20 September 2025) from the OTA Airbase station.

This study analyzes the observed patterns of Generative Artificial Intelligence (Generative AI) use by students in higher education through the lens of the sociotechnical systems (STS) theory, focusing on the academic subsystem. The empirical basis is a survey of 2083 students (3686 responses) from seven countries in Central and Eastern Europe, Central Asia, and Central Africa. Based on these data, two proxy indicators are proposed: A1, reflecting the overall academic use of Generative AI and A2, characterizing the use of Generative AI in a research context. The results show that Generative AI is widely incorporated into students’ academic activities (A1 = 79.06%), while research-oriented use remains less common (A2 = 46.66%) and varies significantly across subsamples. A joint analysis of A1 and A2, visualized as a zoned space A1–A2, reveals different configurations of academic practices: from a predominance of routine educational use to a more pronounced focus on research tasks. Cross-country comparisons show that in certain contexts (e.g., Kazakhstan and one of the Ukrainian subsamples), Generative AI is more often used in a research context, while in other cases, its use remains predominantly educational and routine. In this sense, the results indicate that Generative AI is beginning to fulfill the role of an emerging student research assistant in students’ academic life: technology has already become a familiar tool for completing educational tasks, but its use in supporting research activities remains fragmented. The proposed model and proxy indicators allow us to describe and compare current configurations of Generative AI use in the academic subsystem. The obtained results provide a basis for further research aimed at a deeper understanding of the factors determining the inclusion of Generative AI in student research practice, as well as for the development of management approaches regarding its use in higher education.

22 January 2026

Conceptual zoning of the academic subsystem of student GenAI use along two indicators: A1 (academic use) and A2 (research use).

The Association of Physical Activity with Health Indices and Healthcare Utilization

  • Anastasia Keremi,
  • Antonia Kaltsatou and
  • Gregory Tripsianis
  • + 9 authors

This study aimed to examine the association between physical activity and individuals’ health status, healthcare utilization, socio-demographic characteristics, and health behaviors in a large representative sample from Northern Greece. A cross-sectional study was conducted involving 1227 participants (47.4% males, mean age 49.94 ± 14.87 years) from Thrace, Greece, selected through a two-stage stratified sampling method. According to the Greek version of IPAQ, participants were classified as inactive/insufficiently active, sufficiently and highly active. Data on socio-demographic, lifestyle, and health-related variables were collected through structured interviews. Multivariate logistic regression analysis was performed to determine the independent effect of physical activity on subjects’ characteristics using SPSS ver. 19. Half of the participants (49.8%) were inactive/insufficiently active, 418 participants (34.1%) were sufficiently active, and 198 participants (16.1%) were highly active. In univariate analysis, smoking (p < 0.001), higher coffee consumption (p = 0.002), higher adherence to Mediterranean diet (p < 0.001), napping during the day (p = 0.017) and short sleep duration (p < 0.001) were associated with lower prevalence of high activity. In adjusted analyses, sufficiently active participants had a lower risk for bad self-rated health (aOR = 0.63), hypertension (aOR = 0.41), dyslipidemia (aOR = 0.42), diabetes (aOR = 0.53), obesity (aOR = 0.61), cardiovascular diseases (aOR = 0.43), anxiety (aOR = 0.65), depression (aOR = 0.56), daily sleepiness (aOR = 0.62), poor sleep quality (aOR = 0.71), as well as for primary (aOR = 0.54) and secondary (aOR = 0.40) healthcare utilization compared to inactive participants. Higher-intensity physical activity did not enhance these beneficial effects of sufficient activity on subjects’ characteristics. Physical inactivity significantly compromises health across multiple domains. Promoting even moderate-intensity physical activity may reduce chronic disease burden and healthcare utilization.

21 January 2026

The association of medium physical activity with subjects’ health characteristics and healthcare utilization in relation to low (=reference category) physical activity expressed as adjusted odds ratios (aOR) with their 95% confidence interval (CI) obtained by means of multiple logistic regression models adjusted for socio-demographic characteristics and lifestyle habits.

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Editors: Gassan Hodaifa, Antonio Zuorro, Joaquín R. Dominguez, Juan García Rodríguez, José A. Peres, Zacharias Frontistis, Mha Albqmi

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Sci - ISSN 2413-4155