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Sci

Sci is an international, peer-reviewed, open access journal on all research fields published monthly online by MDPI.

All Articles (468)

Research suggests that overweight/obese adults (BMI ≥ 25 kg/m2) have an elevated risk of cognitive decline. Although exercise is recommended to improve both physical and cognitive health, adherence is often low in this population. Virtual reality (VR) is an emerging strategy that may enhance exercise engagement. This pilot study compared the effects of traditional (TRAD) cycling and VR-based exercise on cognitive performance and prefrontal cortex (PFC) oxygenation (O2Hb). Eleven adults (M = 6, F = 5; BMI: 31.1 ± 2.8 kg/m2; VO2max: 30.4 ± 5.7 mL/kg/min) completed a VO2max test and two 16 min moderate-intensity cycling sessions (TRAD, VR) on separate days, each followed by a Stroop task (four rounds of 30 trials). Exercise intensity did not differ between conditions (TRAD: %HRmax 73.9 ± 4.2, RPE 12.9 ± 1.5, BLa 2.5 ± 1.3; VR: %HRmax 74.0 ± 5.6, RPE 12.7 ± 1.4, BLa 2.7 ± 1.7). Stroop accuracy was similar between conditions; however, response time was faster post-TRAD in round two (p = 0.005) and round three (p = 0.004). No significant differences in PFC O2Hb were observed. These preliminary results suggest that both TRAD cycling and VR-based exercise are feasible modes of moderate-intensity exercise in overweight/obese adults, with largely comparable post-exercise cognitive outcomes. Larger, counterbalanced studies are warranted.

6 January 2026

Study Outline. TRAD = traditional exercise trial, VO2max = maximal oxygen consumption trial, VR = virtual reality.

This study aims to report the first Latvian version of the RESTQ-76, focusing on its internal validity, reliability, structural validity, and the relationships between the factors of the questionnaire. A total of 394 athletes (225 men and 169 women), aged 18–30 years (average age = 21, SD = 1.65), participated in the study. They were recruited from various sports clubs and universities. The RESTQ-76 was translated into Latvian through a forward-backward translation process to ensure accuracy of cultural relevance. To examine the questionnaire’s structure, principal component analysis (PCA) was performed. This analysis revealed a stable four-factor model comprising 18 scales, with acceptable fit indices (RMSEA = 0.089, CFI = 0.914, TLI = 0.896, NFI = 0.889), indicating good model fit. The psychometric validity of the Latvian version is supported by the original, indicating it is appropriate for use in sports settings throughout Latvia. As research on training load and recovery continues to expand, tools like the RESTQ-76 are becoming increasingly important. They help athletes and coaches monitor recovery and stress levels, which is essential for optimizing performance and preventing overtraining in competitive sports.

4 January 2026

RESTQ-76 translation and validation process.

Cervical cancer remains the fourth most common malignancy among women worldwide. Despite well-developed prevention measures, incidence and mortality continue to rise, especially in low- and middle-income countries due to low screening coverage and unavailability of human papillomavirus (HPV) vaccination. The cervical cancer screening coverage could be improved by the implementation of a self-sampling modality for HPV testing. Multiple research pieces support the validity and reliability of a self-sampling modality as an alternative approach to clinician-collected samples for primary cervical cancer screening via HPV genotyping. Moreover, growing research evidence on the self-sampling modality reception shows high acceptance of the method among screened populations. Studies on the self-sampling approach economic efficiency also revealed a high cost-effectiveness of HPV testing through a self-sampling modality compared to other screening modalities for cervical cancer. It is specifically important for low-resource settings, which should use the self-sampling cost advantages to improve cervical cancer screening coverage by attracting underscreened populations. Overall, self-sampling modality has a higher participation rate and better patient satisfaction reported; thus, the method is highly recommended by the World Health Organization for cervical cancer screening.

4 January 2026

Data extraction flowchart.

The Mediterranean Sea is recognized for its high biodiversity but is also a hotspot for pollution. In this study, fish samples of four native marine species were collected from wild catches to determine contaminants such as Anisakis parasites and heavy metals, including nickel, lead, copper, zinc, and chromium, within local marine fish species. The detection of Anisakis parasites was performed by a visual inspection and a digestion method. Metal analysis was carried out on skin, muscle, viscera, and bones of fish, using Microwave Plasma-Atomic Emission Spectroscopy. This study demonstrated that Boops boops was the least infested species by Anisakis parasite, while Scomber colias was the most infested, with Sardinella aurita and Trachurus trachurus showing a lower infestation rate. Pearson correlation statistics revealed that infestation correlated with fish size but not with maturity or sex. Principal component analysis (PCA) demonstrated that the carnivorous species were more prone to Anisakis infestation than the omnivorous species. The maximum levels of copper, nickel, chromium, lead, and zinc content in fish tissues were 13.2 ± 0.11, 19.5 ± 0.02, 19.9 ± 0.01, 28.8 ± 0.09, and 184.87 ± 0.63 µg/g, respectively. PCA revealed that heavy metal contamination does not discriminate between fish species and sex, as opposed to tissue type and location of catch. Some metals, such as zinc and lead, seem to accumulate more in muscle rather than the other tissues. These findings indicate that Anisakis infestation and heavy metal analysis should be monitored and extended beyond the current EU requirements.

31 December 2025

Nematodes isolated from fish samples. The bar (bottom right) indicates 1 mm.

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Editors: Gassan Hodaifa, Antonio Zuorro, Joaquín R. Dominguez, Juan García Rodríguez, José A. Peres, Zacharias Frontistis, Mha Albqmi

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Sci - ISSN 2413-4155