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BioTech, Volume 15, Issue 1

2026 March - 15 articles

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Articles (15)

  • Article
  • Open Access

5 February 2026

Carotenoid-based pigmentation is crucial for the ornamental and commercial value of the cherry shrimp (Neocaridina denticulata sinensis). While several genes are known to influence carotenoid metabolism, the genetic basis for specific color strains r...

  • Article
  • Open Access

5 February 2026

Human embryonic kidney (HEK293) cells are a widespread choice for recombinant protein expression. To optimise yields, the hydrolysate Tryptone N1 (TN1) is commonly added post-transfection. TN1 is obtained by controlled enzymatic digestion of casein....

  • Article
  • Open Access

CRISPR/Cas9-Mediated Knockout of OsHSBP1 Confers Heat Tolerance to Bacthom 7 Elite Rice Cultivar

  • Phuong Duy Nguyen,
  • Van Thi Pham,
  • Ha Thanh Nguyen,
  • Khoa Dang Dang,
  • Tu Tuan Tran,
  • Dai Lan Tran,
  • Thanh Duc Nguyen,
  • Thao Duc Le,
  • Xuan Hoi Pham and
  • Quyen Le Cao
  • + 1 author

4 February 2026

This study investigates the functional role of OsHSBP1, a heat shock factor-binding protein, in regulating abiotic stress tolerance in rice, with the aim of enhancing climate resilience in the elite indica cultivar Bacthom 7 (BT7). Using Clustered Re...

  • Article
  • Open Access
95 Views
22 Pages

Transcriptomic Insights into lncRNA–miRNA–mRNA Networks Regulating Angiogenesis and Metastasis in Prostate Cancer

  • Jonathan Puente-Rivera,
  • Stephanie I. Nuñez Olvera,
  • Ameyatzin Ereth Robles-Chávez,
  • Nayeli Goreti Nieto-Velázquez and
  • María Elizbeth Alvarez-Sánchez

1 February 2026

Prostate cancer (PCa) is a leading cause of cancer-related mortality in men and is often characterized by aggressive growth and bone metastasis. Angiogenesis plays a central role in tumor progression and dissemination. This study aimed to explore the...

  • Review
  • Open Access
157 Views
25 Pages

Bio-Oil from Phototrophic Microorganisms: Innovative Technologies and Strategies

  • Kenzhegul Bolatkhan,
  • Ardak B. Kakimova,
  • Bolatkhan K. Zayadan,
  • Akbota Kabayeva,
  • Sandugash K. Sandybayeva,
  • Aliyam A. Dauletova and
  • Tatsuya Tomo

26 January 2026

The transition to low-carbon energy systems requires scalable and energy-efficient routes for producing liquid biofuels that are compatible with existing fuel infrastructures. This review focuses on bio-oil production from phototrophic microorganisms...

  • Review
  • Open Access
133 Views
19 Pages

TG221: An Experimental Model for Liver Cancer Prevention and Treatment Approaches

  • Elisa Callegari,
  • Angelo Michilli,
  • Farzaneh Moshiri,
  • Bruno De Siena,
  • Laura Gramantieri,
  • Massimo Negrini and
  • Silvia Sabbioni

19 January 2026

Hepatocellular carcinoma (HCC) is a leading cause of cancer mortality. It usually arises in cirrhotic liver, where chronic inflammation and fibrosis create a tumor-permissive microenvironment. Dysregulation of microRNAs (miRNAs), particularly upregul...

  • Review
  • Open Access
243 Views
13 Pages

18 January 2026

By analyzing Food and Drug Administration (FDA) enforcement reports from 2004 to 2025, we can determine the incidence of microbial contamination in non-sterile and sterile drugs in the United States of America and, at the same time, compare the trend...

  • Review
  • Open Access
252 Views
26 Pages

Multi-Scale Transcriptomics Redefining the Tumor Immune Microenvironment

  • Jing Sun,
  • Yingxue Xiao,
  • Lingling Xie,
  • Dan Qin,
  • Yue Zou,
  • Yingying Liu,
  • Yitong Zhai,
  • Minyi Zhang,
  • Tong Li and
  • Bo Li
  • + 1 author

15 January 2026

The tumor immune microenvironment (TIME) is closely involved in tumor initiation, malignant progression, immune escape, and response to immunotherapy. With the continued development of high-throughput sequencing technologies, transcriptomic approache...

  • Review
  • Open Access
1 Citations
166 Views
20 Pages

15 January 2026

Iron-containing alcohol dehydrogenases (Fe-ADHs) from hyperthermophiles represent a distinct class of oxidoreductases characterized by exceptional thermostability, catalytic versatility, and unique metal-dependent properties. Despite considerable seq...

  • Review
  • Open Access
262 Views
27 Pages

12 January 2026

Medicinal honeys from Oceania have gained considerable attention due to their peculiar bioactive constituents and potential health applications. Apart from small molecules such as methylglyoxal and hydrogen peroxide, these honeys are rich in phenolic...

  • Article
  • Open Access
362 Views
27 Pages

6 January 2026

Bacillus-derived lipopeptides are known to possess diverse biological activities, including antimicrobial and anticancer properties, though the mechanisms of such effects at the molecular level remain incompletely understood. We investigated whether...

  • Article
  • Open Access
384 Views
13 Pages

5 January 2026

Torularhodin is the monocyclic C40 carotenoid with the β-ring and a terminal carboxyl group at the acyclic part, with long conjugated double bonds, only synthesized in fungi called red (oleaginous) yeasts, e.g., the genera Rhodotorula and Sporob...

  • Article
  • Open Access
357 Views
23 Pages

Corundum Particles as Trypsin Carrier for Efficient Protein Digestion

  • Sarah Döring,
  • Birte S. Wulfes,
  • Aleksandra Atanasova,
  • Carsten Jaeger,
  • Leopold Walzel,
  • Georg Tscheuschner,
  • Sabine Flemig,
  • Kornelia Gawlitza,
  • Ines Feldmann and
  • Michael G. Weller
  • + 1 author

30 December 2025

Reusable enzyme carriers are valuable for proteomic workflows, yet many supports are expensive or lack robustness. This study describes the covalent immobilization of recombinant trypsin on micrometer-sized corundum particles and assesses their perfo...

  • Article
  • Open Access
372 Views
15 Pages

19 December 2025

The transition toward a circular bioeconomy requires efficient conversion of biogenic wastes and biomass into renewable fuels. This study explores the gasification potential of wastewater sludge (WWS) and food waste (FW), representing high moisture-c...

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BioTech - ISSN 2673-6284