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Background/Objectives: The relationship between occlusion and temporomandibular joint is controversial in the scientific literature. The aim of this study is to evaluate the bone changes in the temporomandibular joint and surrounding bone structures and to determine the effect of malocclusions on the temporomandibular joint by making morphometric measurements in different skeletal classes using three-dimensional cone beam computed tomography images. Methods: A total of 90 patients (30 class I, 30 class II and 30 class III) were included in the study. In each skeletal pattern, condylar osseous changes were evaluated and articular eminence inclination and height, condylar diameters were measured. It was also divided into two age groups: 18–29 and 30 and over. Results: Articular eminence inclination measured with the best-fit line method was significantly higher in Class II compared with class I and III, and in individuals aged ≥30 years. Among osseous changes, only condylar flattening showed a significant age-related increase. The mediolateral condylar diameter was greater in males than females, while the anteroposterior diameter was higher in the ≥30-year age group. Conclusions: Temporomandibular joint morphology demonstrates age- and function-related adaptive remodeling, particularly in articular eminence inclination and condylar dimensions. CBCT-based assessment of these morphological features may assist clinicians in diagnosis and treatment planning, although further studies with larger prospective cohorts are warranted.

10 December 2025

Condyle osseous changes. (A): flattening, (B): sclerosis, (C): erosion, (D): osteophyte, (E): subchondral cyst, (F): bifid condyle, (G1): normal condyle, (G2): reed shape, (H): ankylosis, (I1): pole depression, (I2): normal condyle (J): joint mouse.
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  • Open Access

Triple Renal Artery and Anomalous Origin of the Inferior Phrenic Artery: A Case Report

  • Giovanna de Oliveira Sá Costa,
  • Adler Oliveira Silva Jacó Carvalho and
  • Henrique Montalvão Routman da Cunha
  • + 8 authors

Background/Objectives: Understanding anatomical variations in the abdominal vasculature, particularly of the inferior phrenic arteries (IPAs) and renal arteries (RAs), is essential in surgery and radiology, as such variations directly influence preoperative planning and therapeutic strategies. Although IPAs most commonly arise from the abdominal aorta (AA) or the celiac trunk, and RAs from the AA, anomalous origins have clinical significance, notably the emergence of the IPA from the RA. This study reports the concomitant occurrence of a triple right renal artery and the atypical origin of the ipsilateral inferior phrenic artery. Case Report: During a routine cadaveric dissection, three right renal arteries (superior, middle, and inferior) were identified in an adult male specimen, along with an anomalous origin of the right inferior phrenic artery (RIPA). The RIPA originated from the superior renal artery (SRA), ascended superolaterally to the inferior vena cava and bifurcated at the diaphragmatic dome. The SRA also gave rise to two right inferior suprarenal arteries. Conclusions: The coexistence of a triple renal artery and anomalous origin of the IPA represents an exceptionally uncommon and scarcely reported vascular configuration. This finding underscores the importance of meticulous preoperative vascular mapping, crucial for preventing intraoperative and iatrogenic complications. Broader anatomical and radiological studies are warranted to better elucidate the prevalence, developmental basis, and clinical implications of such variations.

21 November 2025

(A) Posterior view of the Triple RA and anomalous origin of the IPA. Scale Bar: 2.0 cm. (B) Higher magnification. Scale Bar: 0.5 cm. Note: In Figure 1, all abbreviations include an ‘R’ (Right) or ‘L’ (Left) prefix to denote the specific side of the bilateral structure shown in the diagram. The base abbreviations (e.g., RA, MRA) are consistent with the main text.

Human Mandible: Anatomical Variation and Adaptations over the Last 2000 Years

  • Flavio De Angelis,
  • Anna Russo and
  • Antonio Nappo
  • + 8 authors

Background/Objectives: This study explores the evolution and morphology of the human mandible, focusing on recent changes and adaptations over the last 2000 years. It aims to examine how functional, genetic, and environmental factors influence mandibular size, shape, and sexual dimorphism by analyzing key anatomical landmarks—the horizontal ramus (HR), ascending ramus (AR), and mandibular angle (MA). Methods: A retrospective approach was employed using computed tomography (CT) scans of 39 mandibular samples from various historical periods, ranging from the Roman Imperial Age to the present day. Imaging was conducted using a 64-slice multislice computed tomography (MSCT) scanner, and the resulting data were processed to generate detailed 3D reconstructions for morphological assessment. Results: The analysis reveals that present-day samples exhibit significantly less variation in AR and MA compared to archaeological specimens, suggesting a trend of gracilization over time. Statistically significant differences were found in MA, likely influenced by environmental, dietary, and cultural factors. Correlation analysis showed moderate to weak relationships between AR, HR, and MA across sample groups, with significant sexual dimorphism in AR within the archaeological sample. Principal Component Analysis (PCA) further supported these findings, demonstrating a clear distinction between gracile modern mandibles and more robust ancient ones. Conclusions: These findings provide insights into the evolutionary trajectory of the human mandible, underscoring the influence of dietary and cultural shifts on mandibular structure over the past two millennia.

7 November 2025

An informative drawing of a skeletal specimen from which measurements were taken from the lateral projections. AR, MA, and HR refer to the ascending ramus, mandibular angle, and horizontal ramus, respectively.

Mental Eminence in the Historical, Surgical and Anthropological Perspective: A Scoping Review

  • Mauro Vaccarezza,
  • Elena Varotto and
  • Francesco Maria Galassi
  • + 4 authors

The mental eminence (chin) is a uniquely human anatomical feature with critical relevance across multiple domains of biomedical and anthropological research. This transdisciplinary review aims to synthesize current knowledge regarding its morphology, population variability, evolutionary origin, and surgical relevance. A comprehensive scoping review aims to map how the mental eminence has been defined and evaluated in anthropological, forensic research, identifying the main methodological approaches, anatomical landmarks, and sources of morphological variability, as well as the reliability and applicability of current assessment methods in clinical–forensic contexts. The search strategy was performed in October 2025. The authors initially identified 3125 records, and 26 studies were finally included and assessed for qualitative analysis. Moreover, the analysis integrates data from osteological collections, radiographic imaging, and modern morphometric studies. The mental eminence exhibits significant variability across human populations, with pronounced sexual dimorphism and evolutionary distinction from non-human primates. Its emergence in Homo sapiens is a key taxonomic trait. Clinically, the chin serves as a landmark in surgical procedures involving genioplasty, trauma reconstruction, and dental implantology. Recent advances in imaging and biometrics have refined its analysis in both anthropological and diagnostic contexts. Though often overlooked, mental eminence plays a vital role in craniofacial morphology and human evolution. Its study bridges osteology, anthropology, and surgery, offering insight into both phylogenetic development and applied anatomical practice. A multidisciplinary understanding of this structure enhances its diagnostic and therapeutic utility.

6 November 2025

“Mandible. Outer surface. Side view.” From Henry Gray (1825–1861). Anatomy of the Human Body. 1918, online at: https://www.bartleby.com/lit-hub/anatomy-of-the-human-body/fig-176/ (accessed on 2 September 2025), which allows for the visualisation, in its more ventral portion, the osteological architecture of the mental eminence.

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Anatomia - ISSN 2813-0545