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Journal of Cardiovascular Development and Disease, Volume 13, Issue 3

2026 March - 8 articles

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Articles (8)

  • Article
  • Open Access

The Prognostic Value of Left Atrial Size and Strain Assessed by Cardiac Magnetic Resonance in the Coronary Chronic Total Occlusion

  • Jinfan Tian,
  • Wenxiao Xia,
  • Xueyao Yang,
  • Mingduo Zhang,
  • Huijuan Zuo,
  • Libo Liu,
  • Min Zhang,
  • Yuan Zhou,
  • Ziyu An and
  • Xiantao Song
  • + 3 authors

Background: The relationship between left atrial (LA) size, LA strain, and long-term prognosis in patients with coronary chronic total occlusion (CTO) remains unclear. This study aimed to evaluate the association of LA size and LA strain with clinica...

  • Article
  • Open Access

Study on the Role and Mechanism of TOPORS in Regulating Aortic Dissection by Mediating SUMOylation

  • Yuan Hu,
  • Luxi Yang,
  • Wenjun Zhou,
  • Hao Chen,
  • Yuanmin Li,
  • Bing Song and
  • Cuntao Yu

Aortic dissection (AD) is a fatal acute cardiovascular emergency. SUMOylation participates in cell proliferation, apoptosis, and inflammation, but its role in AD, especially via TOPORS, remains unclear. This study investigates how TOPORS regulates AD...

  • Article
  • Open Access

The Impact of Body Mass Index and Nutritional Status on Cardiac Electrophysiological Balance Using ICEB and ICEBc: A Cross-Sectional Approach

  • Fethullah Kayan,
  • Ömer Faruk Alakuş,
  • Mihriban Elçiçek,
  • Serdar Soner,
  • Cansu Öztürk,
  • Geylani Güleken and
  • Ihsan Solmaz

Background: The Index of Cardiac Electrophysiological Balance (ICEB) has emerged as a electrocardiographic marker reflecting the equilibrium between ventricular depolarization and repolarization. Although obesity is known to alter cardiac electrophys...

  • Review
  • Open Access

Antithrombotic Therapy in Percutaneous Atrial Structural Interventions

  • Konstantinos Pitsikakis,
  • Ioannis Skalidis,
  • Emmanuel Skalidis,
  • Dimitrios Lempidakis,
  • Antonios Papoutsakis,
  • Emmanuel Sideras,
  • Evangelos Zacharis,
  • Stylianos Petousis and
  • Michalis Hamilos

Percutaneous left atrial appendage occlusion (LAAO), patent foramen ovale (PFO) closure, and atrial septal defect (ASD) closure rely on temporary antithrombotic therapy to prevent device-related thrombus during endothelialization, yet optimal regimen...

  • Article
  • Open Access
36 Views
18 Pages

Identifying Inadequate Maternal Nutrition in Pregnancies Affected by Fetal Heart Defects: A Feasibility Pilot Study Using Photo-Based Diet Quality Assessment

  • Carson Flamm,
  • Michelle Udine,
  • Sarah Clauss,
  • Anita Krishnan,
  • Mary T. Donofrio,
  • Michele Mietus-Snyder,
  • Gary M. Shaw and
  • Jennifer Klein

Etiologies of congenital heart disease (CHD) are multifactorial. The role of maternal nutrition and environmental factors among these CHD etiologies remain insufficiently understood. This pilot study evaluated the potential association between matern...

  • Review
  • Open Access
50 Views
17 Pages

ROS-Mediated Cardiomyocyte Proliferation and Myocardial Regeneration: Mechanisms and Targeted Strategies for Ischemic Heart Disease

  • Mengqi Chen,
  • Tingting Liu,
  • Fangling Sun,
  • Xin Tian,
  • Wenrong Zheng,
  • Zixin Zhu and
  • Wen Wang

Cardiovascular disease (CVD) persists as the leading cause of global mortality, with adult mammalian hearts exhibiting limited regenerative capacity. Although cardiomyocytes (CMs) can re-enter the cell cycle and undergo DNA synthesis in response to i...

  • Article
  • Open Access
102 Views
12 Pages

Prevalence and Importance of Tricuspid Valve Prolapse in Patients with Primary Mitral Regurgitation

  • Aniek L. van Wijngaarden,
  • Anton Tomsic,
  • Nadeem Elmasry,
  • Hoi W. Wu,
  • Meindert Palmen,
  • Jeroen J. Bax and
  • Nina Ajmone Marsan

The presence and impact of tricuspid valve (TV) prolapse in patients with mitral valve (MV) prolapse and severe mitral regurgitation (MR) have not been widely reported. The aim of our study was to describe the prevalence of TV prolapse, and the assoc...

  • Article
  • Open Access
68 Views
12 Pages

Reproducibility of Echocardiographic Measurements of Right Ventricular Function: Comparison Between TAPSE and TDI S′

  • Gianluca Pagnoni,
  • Dilia Giuggioli,
  • Susan Darroudi,
  • Marco de Pinto,
  • Arianna Maini,
  • Amelia Spinella,
  • Gilda Sandri,
  • Marcello Pinti,
  • Daniela Aschieri and
  • Francesca Coppi
  • + 3 authors

(1) Background: Assessment of right ventricular (RV) function has become increasingly important in echocardiography due to its prognostic significance in cardiac and systemic diseases. (2) Objectives: Tricuspid Annular Plane Systolic Excursion (TAPSE...

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J. Cardiovasc. Dev. Dis. - ISSN 2308-3425