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Journal of Cardiovascular Development and Disease, Volume 13, Issue 3

2026 March - 45 articles

Cover Story: Periprocedural myocardial infarction (MI) after percutaneous coronary intervention remains a controversial entity, particularly in the era of high-sensitivity cardiac troponin assays, which frequently detect biomarker elevations without clear clinical ischemia. This review analyzes the main contemporary definitions of periprocedural MI, including the Fourth Universal Definition of MI, the Academic Research Consortium-2 consensus, and the Society for Cardiovascular Angiography and Interventions criteria, highlighting their differences in biomarker thresholds and ancillary requirements. By examining pathophysiological mechanisms, diagnostic limitations, and prognostic implications, the study underscores the need for more standardized criteria integrating biomarker dynamics with objective evidence of ischemia to improve diagnostic accuracy and clinical relevance. View this paper
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Articles (45)

  • Review
  • Open Access
1,792 Views
21 Pages

Between a Rock and a Hard Place: Balancing Embolic Stroke and Intracerebral Hemorrhage Risk in Left Atrial Appendage Occlusion

  • Juan Felipe Daza-Ovalle,
  • Johanna Seiden,
  • Daniel Labovitz,
  • Erick Daniel Martinez,
  • Deepti Athreya and
  • Charles Esenwa

Patients with atrial fibrillation (AF) who are not candidates for long-term anticoagulation present a complex therapeutic dilemma due to competing risks of cardioembolic stroke and intracerebral hemorrhage (ICH). This challenge is particularly pronou...

(This article belongs to the Special Issue Controversies in Stroke and Cerebrovascular Disease)
  • Article
  • Open Access
1,883 Views
9 Pages

Vertical Right Axillary Thoracotomy for Repair of Ventricular Septal Defects in Infants and Children: Experience with 50 Consecutive Cases

  • Yasin Essa,
  • Ali H. Mashadi,
  • Joseph Giamelli,
  • Alexander Mittnacht,
  • Mahmoud I. Salem and
  • Sameh M. Said

Objectives: Recently, there has been a growing interest in repairing congenital heart defects in children via right axillary thoracotomy. We sought to review our experience with ventricular septal defect closure through this approach. Patients and Me...

(This article belongs to the Section Cardiac Surgery)
  • Article
  • Open Access
973 Views
14 Pages

Out-of-Hospital Cardiac Arrest in Southern Italy: A Retrospective Analysis of 11,653 Cases

  • Luca Gregorio Giaccari,
  • Pasquale Sansone,
  • Nicola D’Angelo,
  • Daniele Antonaci,
  • Eva Epifani,
  • Luciana Mascia,
  • Maria Caterina Pace,
  • Vincenzo Pota and
  • Gaetano Tammaro

(1) Background: Out-of-hospital cardiac arrest (OHCA) remains a major public health issue, with survival largely determined by the initial rhythm and timeliness of resuscitation. Comprehensive population-based data are essential for guiding preventio...

(This article belongs to the Section Epidemiology, Lifestyle, and Cardiovascular Health)
  • Review
  • Open Access
585 Views
10 Pages

Interventional treatment of very elderly patients with severe coronary artery disease is currently one of the central topics in interventional cardiology. Technological progress and increased life expectancy have made these patients appropriate candi...

(This article belongs to the Special Issue Coronary Artery Disease: Risk Stratification and Optimization of Intervention Strategies)
  • Article
  • Open Access
1,048 Views
13 Pages

The ONSET–OFFSET study was a multicentre study assessing the pharmacodynamic responses to ticagrelor and clopidogrel in aspirin-treated patients with chronic coronary syndromes. Recent concerns have been raised about the study methodology, incl...

(This article belongs to the Section Acquired Cardiovascular Disease)
  • Editorial
  • Open Access
703 Views
5 Pages

Transcatheter structural heart procedures, including transcatheter aortic valve replacement (TAVR) and transcatheter edge-to-edge repair (TEER), have revolutionized the management of valvular heart diseases in selected or high-risk patients [...]

(This article belongs to the Special Issue Transcatheter and Surgical Approaches to Complications of Transcatheter Procedures: Current Trends and Future Challenges)
  • Article
  • Open Access
1 Citations
1,170 Views
16 Pages

Background: Hypertension and smoking are well-known risk factors for aortic dissection (AD), but it is unclear whether other lifestyle factors influence the risk. The aim of this study was to investigate the association between diet quality, physical...

(This article belongs to the Special Issue Risk Factors and Prevention of Cardiovascular Diseases—Second Edition)
  • Case Report
  • Open Access
994 Views
8 Pages

First Reported Use of the AMDS Hybrid Prosthesis for Secondary Type A Aortic Dissection After Prior TEVAR

  • Gjoko Boshkoski,
  • Dorgam Natour,
  • Atanas Jankulovski,
  • Thomas Felderhoff and
  • Aron. F. Popov

Type A aortic dissection represents one of the most life-threatening cardiovascular emergencies, with management strategies evolving toward hybrid and endovascular approaches, particularly in high-risk patients. The Ascyrus Medical Dissection Stent (...

(This article belongs to the Section Cardiac Surgery)
  • Article
  • Open Access
849 Views
8 Pages

Background: Few studies have reported electrocardiogram data collected during the neonatal period. The aim of this study was to evaluate electrocardiographic parameters in healthy neonates during the first postnatal hour. Methods: Electrocardiogram s...

(This article belongs to the Section Pediatric Cardiology and Congenital Heart Disease)
  • Case Report
  • Open Access
588 Views
6 Pages

Heart Failure and a Large Ventricular Thrombus Following COVID-19 Infection

  • Jouni Taavitsainen,
  • Ville Vepsäläinen,
  • Juha Hartikainen and
  • Jarkko Hytönen

Severe cases of heart failure (HF), both new onsets of HF and acute exacerbations of chronic HF, are frequently observed during infections. A potentially lethal complication of HF with very low left ventricular ejection fraction is thrombus formation...

(This article belongs to the Section Acquired Cardiovascular Disease)
  • Article
  • Open Access
754 Views
11 Pages

Left Ventricular Mechanics Are Associated with Short-Term Sinus Rhythm Maintenance After Electrical Cardioversion in Atrial Fibrillation

  • Beata Uziębło-Życzkowska,
  • Paulina Skalska,
  • Marek Kiliszek,
  • Małgorzata Kurpaska and
  • Paweł Krzesiński

(1) Background: Electrical cardioversion (ECV) is effective in restoring sinus rhythm (SR) in atrial fibrillation (AF), but the extent of atrioventricular remodeling and determinants of short-term rhythm maintenance remain unclear. This study evaluat...

(This article belongs to the Special Issue Atrial Fibrillation: Current Considerations for Diagnosis, Therapy, and Management)
  • Article
  • Open Access
2 Citations
992 Views
13 Pages

Prognostic Impact of Frailty in Transcatheter Aortic Valve Implantation

  • Ivana Jurin,
  • Daniel Unić,
  • Nikola Pavlović,
  • Marin Pavlov,
  • Savica Gjorgjievska,
  • Tomislav Šipić,
  • Šime Manola,
  • Igor Rudež,
  • Ana Šerman and
  • Irzal Hadžibegović
  • + 2 authors

Background: Frailty strongly influences outcomes after transcatheter aortic valve implantation (TAVI), but conventional risk models insufficiently capture functional and cognitive vulnerability. We compared conventional surgical risk scores with mult...

(This article belongs to the Section Cardiovascular Clinical Research)
  • Article
  • Open Access
1,412 Views
22 Pages

Cardiometabolic abnormalities, which are common in diabetes patients, can be alleviated through exercise. We examined the specific effects of walking (4–5 METS) on diabetic patients’ cardiac function in a randomized study. Patients with t...

(This article belongs to the Section Imaging)
  • Systematic Review
  • Open Access
1 Citations
1,516 Views
26 Pages

Non-invasive ventilation (NIV) reduces mortality in patients with acute cardiogenic pulmonary edema (ACPE). However, the 3CPO trial reported null results. Therefore, we hypothesized that the prevalence of acute coronary syndrome (ACS) would influence...

(This article belongs to the Special Issue Acute Cardiovascular Care in the Cardiological Intensive Care Unit: What Is New?)
  • Article
  • Open Access
994 Views
12 Pages

Nationwide Multicentric Analysis Regarding In-Hospital Complications After Catheter Ablation of Cardiac Arrhythmias

  • Florian Doldi,
  • Christian Meyer,
  • Johannes Brachmann,
  • Fabienne Kreimer,
  • Thorsten Lewalter,
  • Roland Tilz,
  • Malte Kuniss,
  • Ibrahim Akin,
  • Philipp Sommer and
  • Lars Eckardt
  • + 2 authors

Objective and Background: With the increasing use of catheter ablation for tachyarrhythmias, continuous evaluation of in-hospital complications is essential. This study aimed at analyzing complications associated with catheter ablation for atrial fib...

(This article belongs to the Section Cardiovascular Clinical Research)
  • Article
  • Open Access
1 Citations
762 Views
16 Pages

Prognostic Value of a Composite Inflammation–Renal Function Score in Type A Aortic Dissection

  • Rui-Qin Zhou,
  • Yin-Ding Peng,
  • Hao Cai,
  • Cheng Zhang and
  • Qing-Chen Wu

Background and Objectives: Systemic inflammation and renal dysfunction play a central role in the progression and prognosis of type A aortic dissection (TAAD). This study evaluated the SCr score, a composite index combining the systemic inflammation...

(This article belongs to the Special Issue Aortic Surgery—Back to the Roots and Looking to the Future)
  • Case Report
  • Open Access
973 Views
9 Pages

Background: Managing elderly patients with simultaneous acute cardiovascular and orthopedic emergencies presents a unique challenge. While ST-elevation myocardial infarction (STEMI) requires prompt revascularization and dual antiplatelet therapy (DAP...

(This article belongs to the Special Issue Acute Cardiovascular Care in the Cardiological Intensive Care Unit: What Is New?)
  • Article
  • Open Access
566 Views
17 Pages

Time-Varying Prognostic Impact of the Age×BUN/LVEF Index on Long-Term MACCE After ST-Elevation Myocardial Infarction

  • Seda Elcim Yildirim,
  • Tarik Yildirim,
  • Mehmet Tolga Hekim,
  • Tuncay Kiris and
  • Eyüp Avci

Background: Despite advances in reperfusion strategies, long-term major adverse cardiac and cerebrovascular events (MACCE) remain frequent after ST-elevation myocardial infarction (STEMI). Practical risk stratification tools applicable at presentatio...

  • Article
  • Open Access
1,046 Views
14 Pages

(1) Background: Our aim was to evaluate left atrial (LA) volumes and function in patients with newly diagnosed, treatment-naive type 2 diabetes mellitus (T2DM) using Four-Dimensional Automated Left Atrial Quantificative (four-dimensional auto LAQ) an...

(This article belongs to the Topic Cardiac Imaging: State of the Art, 2nd Edition)
  • Article
  • Open Access
2,932 Views
14 Pages

Real-World Outcomes of Inhaled Treprostinil in Pulmonary Hypertension Related to Interstitial Lung Disease: A Multicenter, Retrospective Analysis

  • Andrew R. Kyle,
  • Arun Jose,
  • Kristen Catherman,
  • Jean Elwing,
  • Roxana Sulica,
  • Gerald S. Zavorsky and
  • Namita Sood

Inhaled Treprostinil is the primary treatment of pulmonary hypertension related to interstitial lung disease (PH-ILD). Despite treatment effectiveness in clinical trials, the real-world safety and tolerability of this therapy remains unclear. We cond...

(This article belongs to the Special Issue The Past, Present, and Future of Pulmonary Hypertension: Pathophysiology and Treatment Prospects)
  • Systematic Review
  • Open Access
1,870 Views
14 Pages

Genome-Wide Association Studies of Myocardial Infarction: A Systematic Literature Review

  • Isabelle P. Thierry,
  • Reza Jabbari,
  • Thomas Engstrøm,
  • Jacob Tfelt-Hansen and
  • Charlotte Glinge

Myocardial infarction (MI) remains a leading cause of morbidity and mortality worldwide, which can result in severe complications such as cardiac arrhythmia, heart failure, and sudden cardiac death. Genetic factors contribute to MI etiology and have...

(This article belongs to the Special Issue Feature Review Papers in the ‘Genetics’ Section)
  • Article
  • Open Access
1 Citations
2,081 Views
15 Pages

Muscular VSD Device Complications: Literature Review and Possible Implications for Echocardiographic Follow-Up

  • Micah Tatum,
  • Thomas Casto,
  • Amulya Buddhavarapu,
  • Elizabeth Lyman,
  • Alison Gehred,
  • Benjamin Blais and
  • Clifford L. Cua

Long-term transthoracic echocardiogram (TTE) follow-up guidelines after muscular ventricular septal defect (mVSD) device closure are vague. The primary goal of this study was to perform a literature search to characterize the type and timing of compl...

(This article belongs to the Special Issue Recent Advances in Transcatheter Closure of Atrial Septal Defects (ASD) and Ventricular Septal Defects (VSD))
  • Article
  • Open Access
1,462 Views
13 Pages

Clinical Characteristics and Outcomes of 1894 Women with Peripartum Cardiomyopathy Treated with and Without Levosimendan in Germany

  • Jan A. Kloka,
  • Alexandra Popescu,
  • Benjamin Friedrichson,
  • Thomas Jasny,
  • Lea V. Blum,
  • Stephanie Noone,
  • Armin Flinspach,
  • Peter Kranke,
  • Kai Zacharowski and
  • Vanessa Neef

Background: Peripartum cardiomyopathy (PPCM) is a rare form of heart failure occurring during the last month of pregnancy or within five months postpartum. While levosimendan is considered beneficial in heart failure and cardiogenic shock, evidence s...

(This article belongs to the Special Issue Women and Cardiovascular Disease: The Gender Gap)
  • Correction
  • Open Access
1 Citations
630 Views
2 Pages

Correction: Cicek et al. A New Risk Prediction Model for the Assessment of Myocardial Injury in Elderly Patients Undergoing Non-Elective Surgery. J. Cardiovasc. Dev. Dis. 2025, 12, 6

  • Vedat Cicek,
  • Mert Babaoglu,
  • Faysal Saylik,
  • Samet Yavuz,
  • Ahmet Furkan Mazlum,
  • Mahmut Salih Genc,
  • Hatice Altinisik,
  • Mustafa Oguz,
  • Berke Cenktug Korucu and
  • Ulas Bagci
  • + 2 authors

In the original publication [...]

(This article belongs to the Section Basic and Translational Cardiovascular Research)
  • Article
  • Open Access
1 Citations
839 Views
12 Pages

Endothelial Activation and Stress Index Predicts Poor Coronary Collateral Development in Chronic Total Occlusion

  • Muhammed Ulvi Yalcin,
  • Kadri Murat Gurses,
  • Canan Aydoğan,
  • Sevil Butun,
  • Abdullah Tunçez,
  • Hüseyin Tezcan,
  • Yasin Ozen,
  • Kenan Demir,
  • Nazif Aygul and
  • Bulent Behlul Altunkeser
  • + 4 authors

Background/Objectives: Coronary collateral circulation (CCC) reduces ischemic damage in patients with chronic total occlusion (CTO), yet collateral development varies considerably among individuals. Endothelial stress and systemic inflammation are ke...

(This article belongs to the Topic Biomarkers in Cardiovascular Disease—Chances and Risks, 2nd Volume)
  • Article
  • Open Access
1,102 Views
11 Pages

Central Aortic Cannulation for Total Coronary Revascularization via Anterior Thoracotomy: A Single-Center Initial Experience

  • Tuna Demirkıran,
  • Işıl Taşöz Özdaş,
  • Gizem Işık Ökten,
  • Furkan Burak Akyol,
  • Tayfun Özdem,
  • Yiğit Tokgöz,
  • Hüma Kekeçdil,
  • Murat Kadan and
  • Kubilay Karabacak

Objective: We aimed to evaluate the feasibility, safety, and technical challenges of central aortic cannulation for total coronary revascularization via left anterior thoracotomy (TCRAT). Methods: A retrospective, single-center observational study wa...

(This article belongs to the Special Issue Minimally Invasive Coronary Revascularization: State of the Art)
  • Review
  • Open Access
6 Citations
1,726 Views
34 Pages

Twin Transformation in Cardiothoracic Surgery: The Convergence of Digital Innovation and Sustainability

  • Vasileios Leivaditis,
  • Roman Gottardi,
  • Andreas Antonios Maniatopoulos,
  • Francesk Mulita,
  • Charalampia Pylarinou,
  • Spyros Papadoulas,
  • Konstantinos Nikolakopoulos,
  • Ioannis Panagiotopoulos,
  • Efstratios Koletsis and
  • Anastasios Sepetis
  • + 1 author

Background: Cardiothoracic surgery is among the most technologically advanced and resource-intensive medical specialties, placing it at the intersection of rapid digital innovation and growing demands for environmental sustainability. Addressing thes...

  • Article
  • Open Access
747 Views
13 Pages

Early Prediction of Postoperative Peritoneal Dialysis Using Lung Ultrasound Scoring in Neonates After Cardiopulmonary Bypass

  • Duygu Tunçel,
  • Süleyman Geter,
  • Leyla Şero,
  • Yiğit Kılıç,
  • Nilüfer Okur and
  • Bedri Aldudak

Background: Neonates and young infants undergoing cardiac surgery with cardiopulmonary bypass (CPB) are highly vulnerable to pulmonary dysfunction, systemic inflammation, capillary leak, and fluid overload, which may lead to acute kidney injury (AKI)...

  • Article
  • Open Access
1,343 Views
10 Pages

Exploratory Study of Selective Brain Hypothermia Using Transnasal Evaporative Cooling Under Controlled Normothermia with an Endovascular Device

  • Mitsuaki Nishikimi,
  • Kazuya Kikutani,
  • Mayumi Higashi,
  • Shinichiro Ohshimo,
  • Tatsuhiko Anzai and
  • Nobuaki Shime

Introduction: Selective brain hypothermia has been investigated to improve neurological outcomes in patients with cardiac arrest; however, an optimal clinical method has not yet been established. This study aimed to evaluate the feasibility of a tech...

(This article belongs to the Special Issue Clinical Outcome and Treatment of Cardiac Arrest)
  • Review
  • Open Access
3 Citations
2,113 Views
15 Pages

Artificial Intelligence in Venous Thromboembolism Prevention: A Narrative Review of Machine Learning, Deep Learning, and Natural Language Processing

  • Daniela Nicoleta Crisan,
  • Talida Georgiana Cut,
  • Lucian-Flavius Herlo,
  • Nina Ivanovic,
  • Alexandra Herlo,
  • Luana Alexandrescu,
  • Andreea Sălcudean and
  • Raluca Dumache

Venous thromboembolism (VTE), which includes deep vein thrombosis and pulmonary embolism, is a significant and preventable cause of morbidity and mortality worldwide. Despite the existence of clinical prediction models, biomarker-based risk assessmen...

(This article belongs to the Special Issue Machine Learning and Artificial Intelligence in Cardiovascular Medicine, 2nd Edition)
  • Article
  • Open Access
1 Citations
788 Views
13 Pages

Background: The prevalence of chronic total occlusion (CTO) lesions is as high as 30% in patients undergoing coronary angiography (CAG). Some CTO patients do not undergo revascularization due to procedural complexity and high risks. This study aimed...

(This article belongs to the Special Issue Noninvasive Imaging in Cardiology: From Diagnosis to Treatment)
  • Article
  • Open Access
711 Views
11 Pages

Is Resynchronization Pacing Proarrhythmic Among Congenital Heart Patients? An Evaluation and Review

  • Peter P. Karpawich,
  • Kathleen Zelin,
  • Corinne Biggs,
  • Swati Sehgal,
  • Jennifer Blake,
  • Chenni Sriram and
  • Pooja Gupta

Background: Cardiac resynchronization therapy (CRT) can be an effective form of heart failure (HF) management among congenital heart disease (CHD) patients (pts) with and without surgically repaired defects. However, very long-term results are limite...

(This article belongs to the Section Pediatric Cardiology and Congenital Heart Disease)
  • Article
  • Open Access
744 Views
10 Pages

Valve-Sparing Versus Composite Graft Aortic Root Replacement in Acute Type A Aortic Dissection with Standardized Hemiarch Repair: A Propensity Score Matching Analysis

  • Mohammed Morjan,
  • Tong Li,
  • Luis J. Vallejo Castano,
  • Carlos A. Mestres,
  • Amin Thwairan,
  • Freya S. Jenkins,
  • Hannan Dalyanoglu and
  • Artur Lichtenberg

Objectives: The aim of this study was to compare the short- and long-term results of patients who had received aortic valve-sparing reimplantation (David I procedure) vs. aortic root replacement using a composite graft combined with a hemiarch replac...

(This article belongs to the Special Issue Aortic Surgery—Back to the Roots and Looking to the Future)
  • Article
  • Open Access
765 Views
11 Pages

Background: The optimal management strategy for 50–70% chronic coronary artery stenosis in patients undergoing aortic valve surgery for aortic regurgitation (AR) remains controversial. This study evaluates the prognostic impact of chronic coron...

  • Article
  • Open Access
1,506 Views
16 Pages

Utility of Field Tests for Predicting Cardiorespiratory Fitness and Prescribing Exercise Intensity in Cardiac Rehabilitation Programs: A Randomized Crossover Trial

  • Blake E. G. Collins,
  • Brett A. Gordon,
  • Daniel W. T. Wundersitz,
  • Jayden R. Hunter,
  • Lisa C. Hanson and
  • Michael I. C. Kingsley

The aims of this study are the following: To examine whether field tests predict cardiorespiratory fitness in people with coronary heart disease (CHD) and to determine if heart rate (HR) agreement between the first ventilatory threshold (VT1) and fie...

(This article belongs to the Special Issue Advancing Cardiac Rehabilitation Delivery and Outcomes: Focusing on Exercise and Lifestyle)
  • Article
  • Open Access
1,431 Views
13 Pages

Radiomic Assessment of Epicardial Adipose Tissue for the Prediction of Non-Calcified Coronary Atherosclerotic Plaques

  • Carlo Di Donna,
  • Armando Ugo Cavallo,
  • Eliseo Picchi,
  • Mario Laudazi,
  • Massimo Federici,
  • Marcello Chiocchi and
  • Francesco Garaci

Epicardial adipose tissue (EAT) has previously been associated with coronary artery calcium scores, an increased burden of coronary artery disease (CAD), and features of plaque instability. These associations are likely mediated by endocrine and para...

(This article belongs to the Special Issue Feature Papers in Imaging—Second Edition)
  • Review
  • Open Access
1,904 Views
15 Pages

Periprocedural Myocardial Infarction: Do We Need an Updated Definition?

  • Marcello Casuso Alvarez,
  • Leonardo Luca Bavuso,
  • Michele Di Leo,
  • Marco Basile,
  • Nicolò Vasumini,
  • Tommaso Manaresi,
  • Angelo Maida,
  • Marco Moretti,
  • Daniele Cavallo and
  • Carmine Pizzi
  • + 9 authors

Periprocedural myocardial infarction after percutaneous coronary intervention (PCI) remains a debated entity, especially in the era of high-sensitivity cardiac troponin assays, which frequently detect biomarker rises even when clinically meaningful i...

(This article belongs to the Section Acquired Cardiovascular Disease)
  • Article
  • Open Access
611 Views
15 Pages

The Prognostic Value of Left Atrial Size and Strain Assessed by Cardiac Magnetic Resonance in the Coronary Chronic Total Occlusion

  • Jinfan Tian,
  • Wenxiao Xia,
  • Xueyao Yang,
  • Mingduo Zhang,
  • Huijuan Zuo,
  • Libo Liu,
  • Min Zhang,
  • Yuan Zhou,
  • Ziyu An and
  • Xiantao Song
  • + 3 authors

Background: The relationship between left atrial (LA) size, LA strain, and long-term prognosis in patients with coronary chronic total occlusion (CTO) remains unclear. This study aimed to evaluate the association of LA size and LA strain with clinica...

  • Article
  • Open Access
827 Views
17 Pages

Study on the Role and Mechanism of TOPORS in Regulating Aortic Dissection by Mediating SUMOylation

  • Yuan Hu,
  • Luxi Yang,
  • Wenjun Zhou,
  • Hao Chen,
  • Yuanmin Li,
  • Bing Song and
  • Cuntao Yu

Aortic dissection (AD) is a fatal acute cardiovascular emergency. SUMOylation participates in cell proliferation, apoptosis, and inflammation, but its role in AD, especially via TOPORS, remains unclear. This study investigates how TOPORS regulates AD...

  • Article
  • Open Access
4 Citations
1,128 Views
15 Pages

The Impact of Body Mass Index and Nutritional Status on Cardiac Electrophysiological Balance Using ICEB and ICEBc: A Cross-Sectional Approach

  • Fethullah Kayan,
  • Ömer Faruk Alakuş,
  • Mihriban Elçiçek,
  • Serdar Soner,
  • Cansu Öztürk,
  • Geylani Güleken and
  • Ihsan Solmaz

Background: The Index of Cardiac Electrophysiological Balance (ICEB) has emerged as a electrocardiographic marker reflecting the equilibrium between ventricular depolarization and repolarization. Although obesity is known to alter cardiac electrophys...

(This article belongs to the Topic Cardiovascular Disease in Special Populations: From Basic Science to Clinical Practice)
  • Review
  • Open Access
1 Citations
2,272 Views
16 Pages

Antithrombotic Therapy in Percutaneous Atrial Structural Interventions

  • Konstantinos Pitsikakis,
  • Ioannis Skalidis,
  • Emmanuel Skalidis,
  • Dimitrios Lempidakis,
  • Antonios Papoutsakis,
  • Emmanuel Sideras,
  • Evangelos Zacharis,
  • Stylianos Petousis and
  • Michalis Hamilos

Percutaneous left atrial appendage occlusion (LAAO), patent foramen ovale (PFO) closure, and atrial septal defect (ASD) closure rely on temporary antithrombotic therapy to prevent device-related thrombus during endothelialization, yet optimal regimen...

(This article belongs to the Section Acquired Cardiovascular Disease)
  • Article
  • Open Access
1,359 Views
18 Pages

Identifying Inadequate Maternal Nutrition in Pregnancies Affected by Fetal Heart Defects: A Feasibility Pilot Study Using Photo-Based Diet Quality Assessment

  • Carson Flamm,
  • Michelle Udine,
  • Sarah Clauss,
  • Anita Krishnan,
  • Mary T. Donofrio,
  • Michele Mietus-Snyder,
  • Gary M. Shaw and
  • Jennifer Klein

Etiologies of congenital heart disease (CHD) are multifactorial. The role of maternal nutrition and environmental factors among these CHD etiologies remain insufficiently understood. This pilot study evaluated the potential association between matern...

(This article belongs to the Special Issue Cardiovascular Disease and Nutrition)
  • Review
  • Open Access
2,207 Views
17 Pages

ROS-Mediated Cardiomyocyte Proliferation and Myocardial Regeneration: Mechanisms and Targeted Strategies for Ischemic Heart Disease

  • Mengqi Chen,
  • Tingting Liu,
  • Fangling Sun,
  • Xin Tian,
  • Wenrong Zheng,
  • Zixin Zhu and
  • Wen Wang

Cardiovascular disease (CVD) persists as the leading cause of global mortality, with adult mammalian hearts exhibiting limited regenerative capacity. Although cardiomyocytes (CMs) can re-enter the cell cycle and undergo DNA synthesis in response to i...

(This article belongs to the Special Issue Cutting-Edge Advances in Cardiac Development, Anatomy, and Regeneration)
  • Article
  • Open Access
1,747 Views
12 Pages

Prevalence and Importance of Tricuspid Valve Prolapse in Patients with Primary Mitral Regurgitation

  • Aniek L. van Wijngaarden,
  • Anton Tomsic,
  • Nadeem Elmasry,
  • Hoi W. Wu,
  • Meindert Palmen,
  • Jeroen J. Bax and
  • Nina Ajmone Marsan

The presence and impact of tricuspid valve (TV) prolapse in patients with mitral valve (MV) prolapse and severe mitral regurgitation (MR) have not been widely reported. The aim of our study was to describe the prevalence of TV prolapse, and the assoc...

  • Article
  • Open Access
10 Citations
1,558 Views
12 Pages

Reproducibility of Echocardiographic Measurements of Right Ventricular Function: Comparison Between TAPSE and TDI S′

  • Gianluca Pagnoni,
  • Dilia Giuggioli,
  • Susan Darroudi,
  • Marco de Pinto,
  • Arianna Maini,
  • Amelia Spinella,
  • Gilda Sandri,
  • Marcello Pinti,
  • Daniela Aschieri and
  • Francesca Coppi
  • + 3 authors

(1) Background: Assessment of right ventricular (RV) function has become increasingly important in echocardiography due to its prognostic significance in cardiac and systemic diseases. (2) Objectives: Tricuspid Annular Plane Systolic Excursion (TAPSE...

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J. Cardiovasc. Dev. Dis. - ISSN 2308-3425