1,832,941 Results Found

Osteoarthritis (OA) is a progressive joint disorder affecting over 250 million people globally and is characterized by chronic pain and disability. Among its key pathogenic mechanisms are mitochondrial dysfunction and elevated reactive oxygen species...

Background: Artificial intelligence (AI) is rapidly transforming clinical medicine by enabling earlier disease detection, personalized risk stratification, precision diagnostics, and optimized therapeutic decision-making across multiple specialties....

Biophysics-based, patient-specific modeling remains challenging for clinical translation, particularly for cerebrospinal fluid (CSF) flow where anatomical detail and computational cost are tightly coupled. We present a computational framework for ste...

Background: This study aims to evaluate the effect of hand grip strength (HGS) on perioperative outcomes—particularly postoperative delirium (POD)—in patients scheduled for total knee arthroplasty (TKA). Methods: Older female patients, ag...

The goal of this study was to assess elevated spinal loading conditions and their effect on the polyethylene stresses of a lumbar total joint replacement (L-TJR). A previously validated lumbar spine finite element model was virtually implanted with a...

This article determines the most suitable location for an economy-based logistics center. First of all, among all the provinces in Türkiye, 12 provinces with the most significant deficit in the 8 years covering 2013–2021 and in the estimat...

In customized production environments featuring multi-task parallelism, the efficient adaptability of edge intelligent models is essential for ensuring the stable operation of production lines. However, rapidly generating deployable lightweight model...

This work presents a comparative study of voice activity detection in noise using simple acoustic features and relatively compact recurrent models within a controlled MATLAB-based framework. For each utterance, 9 baseline spectral-plus-periodicity fe...

Background and Clinical Significance: Deficiency of Adenosine Deaminase 2 (DADA2) is a rare monogenic vasculopathy characterised by systemic inflammatory and immunodeficiency features. Although neurological and haematological manifestations are well-...

Procedural knowledge is essential in specialized domains, and natural language tools for retrieving procedural knowledge are necessary for non-expert users to facilitate their understanding and learning. In this study, we focus on function decomposit...

Background: Durvalumab consolidation following radiochemotherapy is now the standard treatment for unresectable stage III non-small cell lung cancer (NSCLC). [18F]FDG PET/CT offers valuable insights not just for staging but also for tumor characteriz...

Sustainable extraction methods represent a key strategy in green chemistry and nutraceutical development, aiming to replace conventional solvent-based techniques while maintaining extract quality and safety. This study compared pistachio (Pistacia ve...

Amphibious light sport aircraft (LSA) combine the versatility of land and water operations but suffer aerodynamic penalties from their inherent design requirements, limiting cruise performance. This study investigates two drag reduction features for...

In this study, equidistant ruled surfaces generated by the Darboux vector, which has significant kinematic importance and characterizes the instantaneous rotation of a moving frame, are investigated specifically for the Frenet frame. By establishing...

To analyze growth trait differences and genetic characteristics of Siniperca chuatsi from distinct geographic populations, whole-genome resequencing was performed on 90 samples from Heilongjiang (HLJ), Hubei (HB), Hunan (HN), and Anhui (AH), and for...

Introduction: Radiotracer-based nuclear imaging, including positron emission tomography (PET) and single-photon emission computed tomography (SPECT), can complement conventional cross-sectional imaging in renal cell carcinoma (RCC) by providing biolo...

A robust audit services market is essential for ensuring financial transparency, regulatory compliance, and investor confidence. As a dimension of organizational sustainability, the capacity of audit firms to remain competitive and resilient under ma...

Permafrost is an important carbon pool for terrestrial ecosystems and a significant source of atmospheric greenhouse gases, but the effects of ground vegetation and snow cover on permafrost greenhouse gas fluxes are still unclear. The soil–atmo...

In this paper, Flare Bright presents flight test results gathered using a ~2m fixed wingspan drone to demonstrate the capability that has been achieved using an Inertial Navigation System (INS) augmented by Machine Learning tuned software. INSs, usin...

Background: The primary objective of this study is to investigate the influence of big data analytics (BDA) on supply chain (SC) risk, SC ambidexterity, and SC resilience. It further examines the effects of SC risk and SC ambidexterity on SC resilien...

To strengthen the safety management and control of explosives in underwater blasting construction sites, this study proposes an improved YOLOv11-based network named CRS-Y, designed to enhance the detection accuracy of explosives in complex underwater...

The decision-making process for the adaptive reuse of cultural heritage requires the evaluation of multiple criteria because of its multifaceted structure. The criteria determined through a literature review were weighted by experts and ranked accord...

Ruminant livestock production faces increasing pressure to reduce environmental impacts while maintaining productivity and food security. This comprehensive review examines current strategies and emerging technologies for enhancing environmental sust...

Vaginal microbiome composition has been linked to risk of preterm birth (PTB), a persistent global health challenge. 16S rRNA microbial profiling has identified specific vaginal community state types (CSTs) that have been associated with PTB risk. Di...

Computational mechanics is one of the techniques used to predict and optimize material behavior and structural performance. However, modeling a complex material model and achieving an accurate response in finite element analysis (FEA) remains a chall...

Physical activity often remains low after hospitalisation for acute exacerbation of Chronic Obstructive Pulmonary Disease (AECOPD). Although post-hospitalisation rehabilitation has shown to support recovery, its impact on daily activity levels in the...

Background: Integrated medical information systems process large volumes of sensitive clinical data and are exposed to persistent cyber threats. Artificial intelligence (AI) is increasingly used for anomaly detection and incident response, yet its sy...

Objectives: The purpose of this study was to evaluate the trends and changes in the time to medical imaging in the emergency department (ED) for patients with cardiopulmonary symptoms during the coronavirus disease 2019 (COVID-19) pandemic. Methods:...

Transmissible gastroenteritis (TGE), caused by the TGE virus (TGEV), is a highly contagious enteric disease characterized by vomiting, dehydration, and watery diarrhea. It mainly endangers piglets within two weeks of age, with a 100% mortality rate,...

Background/Objectives: This study aimed to evaluate the effects of frenulotomy in mother–infant pairs with problematic tongue-tie. Methods: A 2-year prospective observational cohort study was performed. Mother–infant pairs were divided in...

Reliable state estimation in railway environments presents significant challenges due to geometric degeneracy resulting from repetitive structural layouts and point cloud sparsity caused by high-speed motion. Conventional LiDAR-based SLAM systems fre...

Replication stress (RS) is a hallmark of cancer, largely driven by oncogene activation. Due to high levels of RS, cancer cells depend heavily on the RS response mechanisms to avoid DNA damage. This dependency creates a therapeutic opportunity that ca...

Background/Objectives: Glucose Transporter 1 Deficiency Syndrome (GLUT1-DS) is a neurodevelopmental disorder caused by mutations in the gene encoding glucose transporter 1 (GLUT1), which leads to impaired glucose transport into the brain and is chara...

Brazil possesses a large bioenergy resource, embedded in agro-industrial, livestock, and urban residues; this study quantifies its technical magnitude and associated energy value. An assessment was conducted by substrate, combining official statistic...

This study aimed to evaluate the effect of stress attenuators on the tolerance and antioxidant activity of watermelon cultivars under water deficit. The experiment was conducted in two stages, Stage I corresponding to water deficit levels (N1 = 0; N2...

The escalating heat flux density and temperature in highly integrated microelectronic devices adversely affect their reliability and service life, making efficient thermal management crucial for stable operation. This study utilizes Galinstan liquid...

Out-of-hospital cardiac arrest (OHCA) is a major cause of death during mountain activities in the Alpine regions. Due to the time-critical nature of these emergencies and the logistical challenges of remote terrain, emergency medical services (EMS) a...

The high computational demand of dense voxel representations severely limits current vision-centric 3D semantic occupancy prediction methods, despite their capacity for granular scene understanding. This challenge is particularly acute in safety-crit...

Chromium complexes with triamidoamine derivatives bearing bulky substituents at the terminal positions of the ligands, tris(2-(3-pentylamino)ethyl)amine (H3LPen) and tris(2-dicyclohexylmethylaminoethyl)amine (H3LCy), are prepared: [{Cr(LPen)}2(μ-N...

Prescribed fire is a common habitat management tool for white-tailed deer (Odocoileus virginianus Zimm.) that can influence browse quantity and quality. We tested effects of time since burn and number of burns within a decade on browse forage product...

A radioiodine-refractory differentiated thyroid cancer patient with rising serum thyroglobulin (Tg) levels underwent 18F-FDG PET/CT scan, which showed a hypermetabolic region in the proximal segment of esophagus, leading to ambiguity in diagnosis. MR...

Existing experimental findings often prove insufficient for guiding the design of water mist fire extinguishing systems, primarily due to the multitude of interacting factors that influence extinguishing performance. This paper systematically synthes...

Pulse streams in signals sensing multiple objects exhibit flexible features and complex patterns that pose detection challenges from a statistical perspective. We propose a repetitive filtering framework and establish its fundamental properties. By l...

Currently, the general focus of engine-produced pollution reduction lies in exhaust gas aftertreatment methods. This paper attempts a paradigm shift in the field by applying the pre-combustion treatment technologies by fumigation method, which consis...

Brain metastases have a distinctive vascular ecosystem—shaped by sprouting angiogenesis, vessel co-option, vasculogenic mimicry, and tumor cell transdifferentiation—that governs tumor perfusion, drug exposure, and therapeutic responsivene...

In this study, the technical, economic, and environmental performances of a Linear Fresnel Reflector (LFR) integrated with an Organic Rankine Cycle (ORC), designed with a non-storage approach, and a monocrystalline photovoltaic (PV) system were compa...

Background: Postoperative pain levels and opioid requirements vary considerably, even among patients undergoing similar surgical interventions. The pupillary pain index—a pupillometry-derived measure of nociception-antinociception balance&mdash...

A magnetorheological (MR) damper is an intelligent semi-active control device characterized by its output damping force and adjustable coefficient that vary in response to changes in the internal magnetic field. This study proposes a multiphysics cou...

Liquefaction is a critical mechanism amplifying earthquake-induced damage, necessitating systematic hazard assessment through spatially distributed mapping. This study presents a nationwide liquefaction hazard assessment framework for South Korea, in...

To enhance the accuracy of discrete element method (DEM) simulation for the snow removal process performed by autonomous robots on membrane structures, this study calibrated the key contact parameters of snow particles used in the simulation. Through...