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1,830,056 Results Found

  • Article
  • Open Access

2 January 2026

Freshwater scarcity is a critical global challenge, particularly in arid and semi-arid regions like southern Iraq. This study evaluates the thermal and distillate performance of a conventional single-slope solar still under extreme summer conditions...

  • Article
  • Open Access

Background/Objectives: Migraine is a complex neurological headache disorder, and transcutaneous auricular vagus nerve stimulation (taVNS) can effectively relieve headache symptoms, but its mechanism of effect is still unclear. This study aimed to exp...

  • Article
  • Open Access

Star Lightweight Convolution and NDT-RRT: An Integrated Path Planning Method for Walnut Harvesting Robots

  • Xiangdong Liu,
  • Xuan Li,
  • Bangbang Chen,
  • Jijing Lin,
  • Kejia Zhuang and
  • Baojian Ma

2 January 2026

To address issues such as slow response speed and low detection accuracy in fallen walnut picking robots in complex orchard environments, this paper proposes a detection and path planning method that integrates star-shaped lightweight convolution wit...

  • Article
  • Open Access

ATP13A2-Mediated Spermine Export Modulates Lipid Catabolism in the Endolysosomal System of SH-SY5Y Cells

  • Alejandra L. Marcos,
  • Mariela M. Gironacci and
  • Felicitas de Tezanos Pinto

Dysfunction of the membrane transporter P5B-ATPase 13A2 (ATP13A2) has been linked to neurodegenerative disorders, while its overexpression has been associated with colorectal cancer. ATP13A2 localizes to lysosomes and late endosomes, where it exports...

  • Article
  • Open Access

Prediction of Resectability of Peritoneal Disease in Ovarian Cancer Patients Using the Peritoneal Cancer Index (PCI) and Fagotti Score on MRI

  • Marianna Konidari,
  • Sofia Gourtsoyianni,
  • Nikolaos Thomakos,
  • Georgia Lymperopoulou,
  • Chara Tzavara,
  • Vasilios Pergialiotis,
  • Alexandros Rodolakis,
  • Lia Angela Moulopoulos and
  • Charis Bourgioti

2 January 2026

Background/Objectives: Cytoreduction status is a critical prognostic factor in ovarian cancer, yet preoperative selection of patients suitable for primary debulking surgery and accurate prediction of surgical outcome remain challenging. This study ai...

  • Review
  • Open Access

Mitochondrial Health Through Nicotinamide Riboside and Berberine: Shared Pathways and Therapeutic Potential

  • Federico Visalli,
  • Matteo Capobianco,
  • Francesco Cappellani,
  • Lorenzo Rapisarda,
  • Alfonso Spinello,
  • Alessandro Avitabile,
  • Ludovica Cannizzaro,
  • Caterina Gagliano and
  • Marco Zeppieri

Mitochondrial dysfunction represents a central hallmark of aging and a broad spectrum of chronic diseases, ranging from metabolic to neurodegenerative and ocular disorders. Nicotinamide riboside (NR), a vitamin B3 derivative and efficient precursor o...

  • Review
  • Open Access

The Multifaceted Importance of Amphibians: Ecological, Biomedical, and Socio-Economic Perspectives

  • Buddhika Wickramasingha,
  • Josh West,
  • Bellanthudawage Kushan Aravinda Bellanthudawa,
  • Michael P. Graziano and
  • Thilina D. Sursinghe

2 January 2026

Amphibians are among the most threatened vertebrate groups globally, with over 40% of species at risk of extinction. However, a gap remains in understanding how to effectively develop and implement amphibian conservation strategies at local and globa...

  • Article
  • Open Access

2 January 2026

This study examines the determinants of energy efficiency in G20 economies over the period of 2000–2024 using the method of moments quantile regression (MMQR) to analyze the variation in the impacts of green innovation, green investment, green...

  • Article
  • Open Access

2 January 2026

In the face of increasingly severe global environmental challenges, corporate environmental information disclosure (CEID) has become a critical link connecting national ecological governance goals with firms’ green development practices. From t...

  • Article
  • Open Access

2 January 2026

Traditional villages stand as irreplaceable treasures of global cultural heritage, embodying profound historical, cultural, and esthetic values. However, the accelerating pace of urbanization has exposed them to unprecedented threats, including struc...

  • Article
  • Open Access

2 January 2026

Rotating machinery plays a critical role in industrial systems, and effective anomaly detection and assessment are indispensable for ensuring operational safety and reliability. However, the performance of existing methods is often constrained by the...

  • Article
  • Open Access

Computational Investigation of Methoxy Radical-Driven Oxidation of Dimethyl Sulfide: A Pathway Linked to Methane Oxidation

  • Bruce M. Prince,
  • Daniel Vrinceanu,
  • Mark C. Harvey,
  • Michael P. Jensen,
  • Maria Zawadowicz and
  • Chongai Kuang

2 January 2026

Methoxy radicals (CH3O•), formed as intermediates during methane oxidation, may play an underexplored but locally significant role in the atmospheric oxidation of dimethyl sulfide (DMS), a key sulfur-containing compound emitted primarily by mari...

  • Article
  • Open Access

2 January 2026

Psychotropic medicinal plants are commonly used among oncology patients, yet their relevance in the perioperative setting remains insufficiently characterized. We conducted a literature-based identification of 18 neuroactive plants and surveyed 123 c...

  • Article
  • Open Access

Ultrastructural, Osmoregulation, Physiological Metabolism, and Antioxidative Response of Red Tilapia (Oreochromis spp.) Under Acute Alkaline Stress

  • Endalew Alemu,
  • Wei Ye,
  • Jixiang Hua,
  • Lynda Djemaoun,
  • Siqi Lu,
  • Mohamed Fekri Badran,
  • Yalun Dong,
  • Rahma Halim Mahmoud Aboueleila,
  • Mustafa Hassan Lotfy Saleh and
  • Jun Qiang
  • + 1 author

2 January 2026

With increasing global demand for fishery products, saline-alkaline aquaculture has emerged as a potential solution. However, limited information exists regarding the tolerance and adaptability of red tilapia (Oreochromis spp.) to alkaline environmen...

  • Article
  • Open Access

2 January 2026

In order to deeply understand the potential mechanisms underlying the metabolic disorders of Chinese giant salamander (Andrias davidianus), a total of two feeding trials were conducted in the present study. For experiment I, the diets containing five...

  • Systematic Review
  • Open Access

Long-Term Kidney Outcomes After SARS-CoV-2 Infection in Children Aged 0–12 Years: A Systematic Review

  • Saad Alhumaid,
  • Abdullah Abdulrahman Alkhamees,
  • Nourah Al Dossary,
  • Anwar A Almuslim,
  • Rabab Abbas Majzoub,
  • Qasem M. Alalwan,
  • Mohammed Jassim Alsaeed,
  • Fahad Mohammed Aljowaisem,
  • Manahi Ayadh Alqahtani and
  • Abdulmohsen Ibrahim Alamer
  • + 17 authors

2 January 2026

Background: Acute kidney injury (AKI) is increasingly recognised in children with acute COVID-19 and multisystem inflammatory syndrome in children (MIS-C), yet the long-term renal consequences in younger paediatric populations remain unclear. Most st...

  • Article
  • Open Access

As the energy structure evolves, low-load operation of coal-fired boilers is becoming common, posing challenges to combustion stability. This study explored the co-combustion of brown gas (HHO) with bituminous coal and anthracite in a one-dimensional...

  • Article
  • Open Access

2 January 2026

This study evaluated the effects of apple pomace (AP) incorporation on the physicochemical, structural, and functional properties of high-moisture meat analogs from a sustainability perspective. AP, an abundant agro-industrial by-product rich in diet...

  • Article
  • Open Access

Fire-Resistant Steel Structures: Optimization Mathematical Model with Minimum Predicted Cost of Fire Protection Means

  • Marina Gravit,
  • Anton Radaev,
  • Nikita Shcheglov,
  • Natalia Konstantinova and
  • Alla Tsepova

2 January 2026

Steel structures quickly lose stability during a fire, which is why fire protection measures are used to increase their fire resistance limits. Structural fire protection in the form of boards or covers can achieve structural stability values ranging...

  • Article
  • Open Access

2 January 2026

Based on micro-level job seeker data from 41 cities in China’s Yangtze River Delta, this study employs threshold regression to examine how inter-city distance influences talent mobility. The results reveal that distance exerts a negative impact...

  • Article
  • Open Access

Despite years of study, the biological role of the human proinsulin connecting peptide (C-peptide) remains poorly understood. Nevertheless, the C-peptide exhibits subdomains including conserved residues that are thought to have co-evolved with the in...

  • Article
  • Open Access

A Mechanical Error Correction Algorithm for Laser Human Body Scanning System

  • Yue Wang,
  • Jun Ren,
  • Yuan Xue,
  • Kaixuan Liu,
  • Fei Ma and
  • Maoya Yang

2 January 2026

Human body measurement involves large-scale measurement. The acquisition of three-dimensional spatial coordinate data is a complex process. The errors which are generated in each stage of the process can potentially affect the final measurement data....

  • Article
  • Open Access

One of the major challenges for effective intrusion detection systems (IDSs) is continuously and efficiently incorporating changes on cyber-attack tactics, techniques, and procedures in the Internet of Things (IoT). Semi-automated cross-organizationa...

  • Article
  • Open Access

Microbial Distribution and Biofilm-Forming Capacity in the Reproductive Tract of Farm Ruminants

  • Charinya So-In,
  • Natchaporn Piamalung,
  • Aomsab Kongkaew,
  • Phiyakorn Sriarun,
  • Benyapa Kammungkun,
  • Sawarod Phongchaiwasin,
  • Bongkodkanok Somwaeng,
  • Wichayada Haputon,
  • Thanchanok Wadmuang and
  • Surasak Khankhum
  • + 1 author

2 January 2026

Reproductive problems in farm ruminants are often linked to imbalances in the microorganisms living in the reproductive tract and their ability to form biofilms. This study examined the presence of bacteria and their biofilm-forming capacity in cows...

  • Article
  • Open Access

Cost-Effectiveness Analysis of an Intracranial Stereotactic Radiotherapy Service for Brain Metastasis in a North Queensland Regional Cancer Centre

  • Qichen Zhang,
  • Lan Gao,
  • Neha Das,
  • Timothy Squire,
  • Daniel Stoker,
  • Reshma Shakya,
  • Deepti Patel,
  • Abhishek Joshi and
  • Tao Xing

2 January 2026

Introduction: Intracranial stereotactic radiosurgery (SRS) is a specialised radiotherapy technique that plays an essential role in achieving local control of brain metastases and therefore optimising quality of life for many cancer patients. It also...

  • Article
  • Open Access

2 January 2026

Indonesia faces growing pressure to strengthen waste management while expanding renewable energy generation, particularly from high-moisture biomass such as palm oil mill effluent (POME) and the organic fraction of municipal solid waste (OFMSW). Anae...

  • Article
  • Open Access

2 January 2026

This study evaluates the shear strength of precast concrete beam–column joints using a Combined Model based on the ACI code, with implications for sustainable structural design. A database of 87 specimens from the existing literature was compil...

  • Article
  • Open Access

2 January 2026

Heavy metals (arsenic, cadmium, and lead) remain one of the most common and complex environmental problems worldwide. Accordingly, there is a growing need for eco-friendly and affordable materials derived from agricultural waste for the removal of he...

  • Systematic Review
  • Open Access

2 January 2026

The growth of cultural tourism is one of the key areas supporting Indonesia’s policy direction for 2025–2030. This focus aligns with Pillar 8 of the Sustainable Development Goals (SDGs), which promotes decent work and economic growth. Bas...

  • Article
  • Open Access

Minimally Invasive Aortic Valve Replacement in Elderly Patients: Insights from a Large Cohort

  • Lukman Amanov,
  • Arian Arjomandi Rad,
  • Sadeq Ali-Hasan-Al-Saegh,
  • Antonia Annegret Jauken,
  • Prokopis-Andreas Zotos,
  • Thanos Athanasiou,
  • Stefan Ruemke,
  • Jan Karsten,
  • Jawad Salman and
  • Fabio Ius
  • + 5 authors

2 January 2026

Background/Objectives: Transcatheter aortic valve implantation (TAVI) has become the leading treatment option for patients suffering from aortic valve stenosis aged over 70, except in cases of specific contraindications like bicuspid valves, inapprop...

  • Systematic Review
  • Open Access

Background/Objectives: Mature adipocytes were previously regarded as terminally differentiated cells that are restricted to lipid storage. Recent studies have shown that they can dedifferentiate into fibroblast-like progenitor cells, termed dediffere...

  • Article
  • Open Access

Control of Exposure Assessment Parameters to Ionising Radiation Under New Air Exchange (Ventilation) Conditions: A Case Study of the Underground Tourist Route in Książ

  • Katarzyna Wołoszczuk,
  • Agata Grygier,
  • Krystian Skubacz,
  • Eliška Fialová,
  • Petr P. S. Otahal,
  • Zuzanna Pawłowska,
  • Dagmara Eulalia Tchorz-Trzeciakiewicz and
  • Mirosław Szyłak-Szydłowski

2 January 2026

Radon (222Rn) is a naturally occurring radioactive noble gas that is a major source of ionising radiation in the environment. Many measurement techniques can be used to monitor 222Rn concentrations in the workplace. The main purpose of conducting suc...

  • Article
  • Open Access

2 January 2026

Megacity regions mark a transformative phase of urbanisation, in which interconnected cities undergo land-use and land-cover change (LUCC) that extends beyond administrative boundaries. However, the drivers of cross-boundary LUCC remain insufficientl...

  • Article
  • Open Access

2 January 2026

While the legal framework in Mozambique in principle provides equal rights to land for women and men, its underlying assumptions imply that customary tenure is patrilineal, that women get access to land through their relationships with men, while men...

  • Article
  • Open Access

2 January 2026

Cultural tourism has emerged as a key factor in destination development, but moving from growth-oriented expansion to sustainability necessitates a better comprehension of the psychological processes influencing visitor involvement. Existing studies...

  • Article
  • Open Access

2 January 2026

The integrated platform provides a safe operating environment for high-rise residential construction and enables the simultaneous advancement of main structural works and facade operations. However, the construction workflow based on an integrated pl...

  • Article
  • Open Access

Exploring the Risk: Investigating the Association Between Elderly-Onset Sarcoidosis (EOS) and Malignancy

  • Ahmed Ehab,
  • Axel T. Kempa,
  • Ahmad Shalabi,
  • Noha Elkateb,
  • Nesrine Saad Farrag and
  • Heba Wagih Abdelwahab

Background: Elderly-onset sarcoidosis > 65 (EOS) is rare and occurs in patients over 65. Studies on its incidence, clinical features, and treatment are limited, and its link to malignancy remains complex. Objectives: In this study, we aimed to ana...

  • Article
  • Open Access

Clinical, Endoscopic, and Histological Characteristics of Severe Immune Checkpoint Inhibitor-Induced Colitis

  • Diego Casas Deza,
  • Cristina Polo Cuadro,
  • Marta Gascón Ruiz,
  • Manuel Barreiro-de Acosta,
  • Míriam Mañosa,
  • Francisco Rodríguez-Moranta,
  • Yamile Zabana,
  • Elena Céspedes Martínez,
  • Ingrid Ordás and
  • José Miranda Bautista
  • + 42 authors

2 January 2026

Background: Immune checkpoint inhibitors (ICIs) have revolutionized cancer therapy. They can cause immune-mediated colitis (IMC), a potentially severe adverse event. Current data on severe IMC (grade 3–4) are limited, particularly regarding cli...

  • Case Report
  • Open Access

A Case of Double Superior Vena Cava with a Rare Accessory Hemiazygos Arch Crossing over the Descending Aorta in a Male Body Donor

  • Sandeep Silawal,
  • Mustafa Kandemir,
  • Franz Stelzl,
  • Valentina Oberguggenberger,
  • Kristinko Martinovic,
  • Maria Kokozidou,
  • Niels Hammer and
  • Gundula Schulze-Tanzil

While performing a routine anatomical dissection on a male donor, undergraduate medical students observed an uncommon vascular anomaly: a persistent left superior vena cava (LSVC). Prior to the anatomical dissection, computed tomography (CT) images w...

  • Article
  • Open Access

High-Frequency Induction Drive Analysis for Common Mode and Differential Mode Impedance Characteristics

  • Kashif Imdad,
  • Humayun Salahuddin,
  • Zeeshan Ahmad Arfeen,
  • Ghulam Amjad Hussain,
  • Zeeshan Rashid,
  • Nusrat Husain and
  • Muhammad Salman Saeed

2 January 2026

The parasitic currents issue arises in induction machines operating at higher frequencies. The parasitic current flow is the main cause of premature degradation of winding insulation deterioration and bearing damage. The effect of electromagnetic int...

  • Article
  • Open Access

Recovery of IR700 Fluorescence After Near-Infrared Photoimmunotherapy: Discovery and Mechanistic Insights

  • Hideki Tanaka,
  • Shuhei Okuyama,
  • Ken Shirota,
  • Mayumi Sugahara,
  • Akiko Banba,
  • Akihiro Ishikawa,
  • Nobuhisa Minakata,
  • Hirobumi Fuchigami,
  • Masahiro Yasunaga and
  • Tomonori Yano

2 January 2026

Background/Objectives: Near-infrared photoimmunotherapy (NIR-PIT) is a molecularly targeted cancer therapy that employs antibody–photoabsorber conjugates (APCs) comprising the photosensitizer IRDye700DX (IR700) and tumor-specific antibodies. Fo...

  • Article
  • Open Access

2 January 2026

This study evaluates an integrated approach for recovering lead and silver from lead cake through chlorination roasting followed by acid leaching. The lead cake originates from sulfuric acid leaching of zinc ferrite residues obtained during the hydro...

  • Article
  • Open Access

Background: Antimicrobial resistance (AMR) is a major global health threat, and Cyprus reports one of the highest levels of community antibiotic consumption in the EU. Despite their central role in antibiotic access and counselling, the stewardship p...

  • Article
  • Open Access

Floods are among the most destructive natural disasters, posing major challenges to human safety, property, and urban resilience. Effective communication of flood risk is therefore crucial for disaster preparedness and the sustainable management of s...

  • Article
  • Open Access

2 January 2026

The rapid development of intelligent transportation systems and autonomous driving technologies has made visual perception a key component in ensuring safety and improving efficiency in complex traffic environments. As a core task in visual perceptio...

  • Article
  • Open Access

Organoids consisting of primary human cells, i.e., astrocytes, pericytes, and endothelial cells, form a functional blood–brain barrier (BBB) in vitro. The ability of FITC-dextran (70 kDa), calcium phosphate nanoparticles (100 nm), Escherichia c...

  • Article
  • Open Access

Is Dexamethasone Helpful in Reducing Perihematoma Edema and for the Outcome of Intracerebral Hemorrhage?

  • Jayantee Kalita,
  • Sandeep Kumar Gupta,
  • Dhiraj Kumar,
  • Firoz M. Nizami,
  • Prakash C. Pandey,
  • Roopali Mahajan and
  • Vivek Singh

2 January 2026

Background: In primary supratentorial intracerebral hemorrhage (PSICH), dexamethasone (Dexa) may be effective in reducing perihematoma edema (PHE). We compare the changes in the PHE, hematoma edema complex (HEC), and midline shift (MLS) in patients w...

  • Article
  • Open Access

Emergence of OXA-48-like Carbapenemase-Producing Escherichia coli in Baranya County, Hungary

  • Fatma A. Mohamed,
  • Mohamed Al-Bulushi,
  • Szilvia Melegh,
  • Bálint Timmer,
  • Réka Meszéna,
  • Csongor Freytag,
  • Levente Laczkó,
  • László Miló,
  • Péter Urbán and
  • Renáta Bőkényné-Tóth
  • + 6 authors

Background: Carbapenem-resistant Escherichia coli (CREC) producing OXA-48-like carbapenemase was first detected in Hungary in 2022. The aim of the present study was to characterize such strains isolated in 2022–2025 in Baranya County, Hungary....

  • Article
  • Open Access

The integration experiences and vulnerabilities of migrants in host states are a critical area of study. This qualitative research, grounded in a human rights and social justice framework, investigates the systemic injustices and integration challeng...

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