Although ubiquitously present, the relevance of cilia for vertebrate development and health has long been underrated. However, the aberration or dysfunction of ciliary structures or components results in a large heterogeneous group of disorders in mammals, termed ciliopathies. The majority of human ciliopathy cases are caused by malfunction of the ciliary dynein motor activity, powering retrograde intraflagellar transport (enabled by the cytoplasmic dynein-2 complex) or axonemal movement (axonemal dynein complexes). Despite a partially shared evolutionary developmental path and shared ciliary localization, the cytoplasmic dynein-2 and axonemal dynein functions are markedly different: while cytoplasmic dynein-2 complex dysfunction results in an ultra-rare syndromal skeleto-renal phenotype with a high lethality, axonemal dynein dysfunction is associated with a motile cilia dysfunction disorder, primary ciliary dyskinesia (PCD) or Kartagener syndrome, causing recurrent airway infection, degenerative lung disease, laterality defects, and infertility. In this review, we provide an overview of ciliary dynein complex compositions, their functions, clinical disease hallmarks of ciliary dynein disorders, presumed underlying pathomechanisms, and novel developments in the field. Full article

Humans are the product of what society and their environment conditions them into being. People living in metropolitan cities have a very fast-paced life and are constantly exposed to different situations. A social media platform enables individuals to express their emotions and sentiments and thus acts as a reservoir for the digital emotion footprints of its users. This study proposes that the user data available on Twitter has the potential to showcase the contrasting emotions of people residing in a pilgrimage city versus those residing in other, non-pilgrimage areas. We collected the Arabic geolocated tweets of users living in Mecca (holy city) and Riyadh (non-pilgrimage city). The user emotions were classified on the basis of Plutchik’s eight basic emotion categories, Fear, Anger, Sadness, Joy, Surprise, Disgust, Trust, and Anticipation. A new bilingual dictionary, AEELex (Arabic English Emotion Lexicon), was designed to determine emotions derived from user tweets. AEELex has been validated on commonly known and popular lexicons. An emotion analysis revealed that people living in Mecca had more positivity than those residing in Riyadh. Anticipation was the emotion that was dominant or most expressed in both places. However, a larger proportion of users living in Mecca fell under this category. The proposed analysis was an initial attempt toward studying the emotional and behavioral differences between users living in different cities of Saudi Arabia. This study has several other important applications. First, the emotion-based study could contribute to the development of a machine learning-based model for predicting depression in netizens. Second, behavioral appearances mined from the text could benefit efforts to identify the regional location of a particular user. Full article

5-Lipoxygenase (5-LOX) plays a key role in inflammation through the biosynthesis of leukotrienes and other lipid mediators. Current evidence suggests that dietary (poly)phenols exert a beneficial impact on human health through anti-inflammatory activities. Their mechanisms of action have mostly been associated with the modulation of pro-inflammatory cytokines (TNF-α, IL-1b), prostaglandins (PGE₂), and the interaction with NF-kB and cyclooxygenase 2 (COX-2) pathways. Much less is known about the 5-lipoxygenase (5-LOX) pathway as a target of dietary (poly)phenols. This systematic review aimed to summarize how dietary (poly)phenols target the 5-LOX pathway in preclinical and human studies. The number of studies identified is low (5, 24, and 127 human, animal, and cellular studies, respectively) compared to the thousands of studies focusing on the COX-2 pathway. Some (poly)phenolics such as caffeic acid, hydroxytyrosol, resveratrol, curcumin, nordihydroguaiaretic acid (NDGA), and quercetin have been reported to reduce the formation of 5-LOX eicosanoids in vitro. However, the in vivo evidence is inconclusive because of the low number of studies and the difficulty of attributing effects to (poly)phenols. Therefore, increasing the number of studies targeting the 5-LOX pathway would largely expand our knowledge on the anti-inflammatory mechanisms of (poly)phenols. Full article

As it is the seventh most-spoken language and fifth most-spoken native language in the world, the domain of Bengali handwritten character recognition has fascinated researchers for decades. Although other popular languages i.e., English, Chinese, Hindi, Spanish, etc. have received many contributions in the area of handwritten character recognition, Bengali has not received many noteworthy contributions in this domain because of the complex curvatures and similar writing fashions of Bengali characters. Previously, studies were conducted by using different approaches based on traditional learning, and deep learning. In this research, we proposed a low-cost novel convolutional neural network architecture for the recognition of Bengali characters with only 2.24 to 2.43 million parameters based on the number of output classes. We considered 8 different formations of CMATERdb datasets based on previous studies for the training phase. With experimental analysis, we showed that our proposed system outperformed previous works by a noteworthy margin for all 8 datasets. Moreover, we tested our trained models on other available Bengali characters datasets such as Ekush, BanglaLekha, and NumtaDB datasets. Our proposed architecture achieved 96–99% overall accuracies for these datasets as well. We believe our contributions will be beneficial for developing an automated high-performance recognition tool for Bengali handwritten characters. Full article

This study investigated, for the first time, the age and growth of the spotted lanternfish Myctophum punctatum through an analysis of otolith microstructure. A total of 377 individuals were collected from the Strait of Messina (central Mediterranean Sea), ranging between 20.3 and 73.7 mm of standard length. Their length–weight relationship was estimated, and these outputs indicated an isometric growth, for all specimens and when males and females were analysed separately. The sagittal otoliths were removed from 185 fish, although the microincrement readings were considered valid for only 173 otoliths. Microincrement counts ranged from 32 to 48 (average = 37.6) in the otolith central zone, 30 to 56 (average = 44.3) in the middle zone, and 36 to 384 (average = 165.5) in the external zone. Overall, total microincrements ranged between 106 and 469. Different growth models (Gompertz, von Bertalanffy and logistic models) were considered, to understand which one fit best in describing the growth patterns in M. punctatum. The Gompertz model was then selected as the best-fitting model and its parameters for all individuals were L_∞ = 74.79, k = 0.0084 and I = 139.60. Full article

Compared with other materials, high-volume fraction aluminum-based silicon carbide composites (hereinafter referred to as SiCp/Al) have many advantages, including high strength, small change in the expansion coefficient due to temperature, high wear resistance, high corrosion resistance, high fatigue resistance, low density, good dimensional stability, and thermal conductivity. SiCp/Al composites have been widely used in aerospace, ordnance, transportation service, precision instruments, and in many other fields. In this study, the ABAQUS/explicit large-scale finite element analysis platform was used to simulate the milling process of SiCp/Al composites. By changing the parameters of the tool angle, milling depth, and milling speed, the influence of these parameters on the cutting force, cutting temperature, cutting stress, and cutting chips was studied. Optimization of the parameters was based on the above change rules to obtain the best processing combination of parameters. Then, the causes of surface machining defects, such as deep pits, shallow pits, and bulges, were simulated and discussed. Finally, the best cutting parameters obtained through simulation analysis was the tool rake angle γ₀ = 5°, tool clearance angle α₀ = 5°, corner radius r = 0.4 mm, milling depth a_p = 50 mm, and milling speed v_c= 300 m/min. The optimal combination of milling parameters provides a theoretical basis for subsequent cutting. Full article

Background: The use of electric scooters has increased considerably as they are an accessible means of transportation. The number of injuries from falls and collisions has risen significantly. Therefore, the aim of the study was to describe demographics injury patterns of electric scooter accidents produced over one year. Methods: A prospective observational study of electric scooter- related injuries presented in the emergency room from May 2019 until May 2020. The inclusion criteria was based on the direct cause of injury produced while an electric scooter was in use. Demographic data, the use of a helmet or the lack thereof, accident mechanism, injury time, type of injury produced, and the treatment applied were collected. Results: Over the study period, 397 patients were identified with a total of 422 injuries. The mean age was 30.8 years, with 12.6% of patients being minors. The patients mainly presented in evening hours and in summertime at the emergency department. Of the total injuries seen, 46.9% were fractures. Some 25% of the total cases required surgery. Only 19% of the riders wore a helmet at the time of the accident. Most of the fractures were to the upper limbs (62.6%). There was a greater incidence of radius fractures. Conclusion: Injuries incurred while using electric scooters are an emerging phenomenon, despite existing regulations. In this study, most injuries occurred in young men and were due to falls from the vehicle. Nearly half of those injuries were fractures to the upper limbs. Surprisingly, 50% of the fractures required surgery. Full article

Cross-laminated Timber (CLT) has become an emerging board material of wood construction that is strong enough to sustain a high-rise building. However, many wooden congregate housing units overseas that utilize CLT have poor sound environments because the low mass of such wood influences sound insulation performance. In this research, we explored the effect of different CLT walls on sound insulation performance and integrated applicable sound insulation simulation tools to simplify the process of designing a CLT wall structure. This research aimed at a double wall and CLT combined with a gypsum board as the research object. The sound insulation performance test was carried out in a laboratory, while the sound insulation performance of the structure was predicted through simulation tools and prediction models and then compared with the measured values to verify the applicability of the simulation tool. The CLT with a double wall and CLT with gypsum board (CLT + GB) achieved of 50 dB. The numerical simulation had better prediction performance than INSUL at the double wall, while the double wall with cavity structure was close to the measured result via mass law calculation. The INSUL-predicted CLT with a gypsum board at 500 Hz~3150 Hz was close to the measured value. Full article

In contemporary wireless communication systems, the multiple-input and multiple-output systems are extensively utilized due to their enhanced spectral efficiency and diversity. Densely packed antenna arrays play an important role in such systems to enhance their spatial diversity, array gain, and beam scanning capabilities. In this article, a slotted meta-material decoupling slab (S-MTM-DS) with dual reflexes slotted E-shapes and an inductive stub is proposed. Its function was validated when located between two microstrip patch antenna elements to reduce the inter-element spacing, the mutual coupling, the return losses, and manufacturing costs due to size reduction. A prototype is simply fabricated in a volume of 67.41 × 33.49 × 1.6 mm³ and frequency-span measured from 8.4:11 GHz. At 9.4 GHz frequency, the spaces between the transmitting elements are decreased to 0.57 of the free space wavelength. When the proposed isolation S-MTM-DS is applied, the average isolation among them is measured to be −36 dB, the operational bandwidth is enhanced to be 1.512 GHz, the fractional bandwidth improved to be 16.04%, and the return losses are decreased to be −26.5 dB at 9.4 GHz center frequency. Consequently, the proposed design has the potential to be implemented simply in wireless contemporary communication schemes. Full article

Superoxide dismutase (SOD) is an important enzyme that acts as the first line of protection in the plant antioxidant defense system, involved in eliminating reactive oxygen species (ROS) under harsh environmental conditions. Nevertheless, the SOD gene family was yet to be reported in rapeseed (Brassica napus L.). Thus, a genome-wide investigation was carried out to identify the rapeseed SOD genes. The present study recognized 31 BnSOD genes in the rapeseed genome, including 14 BnCSDs, 11 BnFSDs, and six BnMSDs. Phylogenetic analysis revealed that SOD genes from rapeseed and other closely related plant species were clustered into three groups based on the binding domain with high bootstrap values. The systemic analysis exposed that BnSODs experienced segmental duplications. Gene structure and motif analysis specified that most of the BnSOD genes displayed a relatively well-maintained exon–intron and motif configuration within the same group. Moreover, we identified five hormones and four stress- and several light-responsive cis-elements in the promoters of BnSODs. Thirty putative bna-miRNAs from seven families were also predicted, targeting 13 BnSODs. Gene ontology annotation outcomes confirm the BnSODs role under different stress stimuli, cellular oxidant detoxification processes, metal ion binding activities, SOD activity, and different cellular components. Twelve BnSOD genes exhibited higher expression profiles in numerous developmental tissues, i.e., root, leaf, stem, and silique. The qRT-PCR based expression profiling showed that eight genes (BnCSD1, BnCSD3, BnCSD14, BnFSD4, BnFSD5, BnFSD6, BnMSD2, and BnMSD10) were significantly up-regulated under different hormones (ABA, GA, IAA, and KT) and abiotic stress (salinity, cold, waterlogging, and drought) treatments. The predicted 3D structures discovered comparable conserved BnSOD protein structures. In short, our findings deliver a foundation for additional functional investigations on the BnSOD genes in rapeseed breeding programs. Full article

Thoracic endovascular aortic repair (TEVAR) is a life-saving therapy for type B aortic dissection (TBAD). However, surveillance computed tomography (CT) scans in post-TEVAR patients are associated with high radiation dose, thus resulting in potential risk of radiation-induced malignancy. In this study, we developed a patient-specific three-dimensional (3D) printed phantom with stent grafts in situ, then scanned the phantom with different CT protocols to determine the optimal scanning parameters for post-treatment patients. The CT scans were conducted with different kVp and pitch values (80, 100, 120 kVp and pitch of 1.2, 1.5, 2.0, 2.5), resulting in a total of 12 datasets. Signal-to-noise ratio (SNR) was measured to determine and compare the image quality between different datasets. Results showed no significant differences in SNR between different kVp when the pitch value was 1.2. At low pitch values, a decrease in kVp from 120 to 80 led to a significant effective dose reduction by more than 20%. SNR decreased by 30% when pitch was increased from 1.2 to 2.5 at 80 kVp, and 20% at 120 kVp. In contrast, there was only a 3.9% decrease in SNR when kVp was reduced from 120 to 80 at pitch 1.2, and 15.9% at pitch 2.5. High pitch with 100 kVp can effectively reduce the dose while maintaining image quality. Full article

Objective: There is growing evidence that in adults, higher levels of handgrip strength (HGS) are linked to better cognitive performance. However, the relationship between HGS and cognitive performance has not been sufficiently investigated in special cohorts, such as individuals with hypertension who have an intrinsically higher risk of cognitive decline. Thus, the purpose of this study was to examine the relationship between HGS and cognitive performance in adults with hypertension using data from the Global Ageing and Adult Health Survey (SAGE). Methods: A total of 4486 Chinese adults with hypertension from the SAGE were included in this study. Absolute handgrip strength (aHGS in kilograms) was measured using a handheld electronic dynamometer, and cognitive performance was assessed in the domains of short-term memory, delayed memory, and language ability. Multiple linear regression models were fitted to examine the association between relative handgrip strength (rHGS; aHGS divided by body mass index) and measures of cognitive performance. Results: Overall, higher levels of rHGS were associated with higher scores in short-term memory (β = 0.20) and language (β = 0.63) compared with the lowest tertiles of rHGS. In male participants, higher HGS was associated with higher scores in short-term memory (β = 0.31), language (β = 0.64), and delayed memory (β = 0.22). There were no associations between rHGS and cognitive performance measures in females. Conclusion: We observed that a higher level of rHGS was associated with better cognitive performance among hypertensive male individuals. Further studies are needed to investigate the neurobiological mechanisms, including sex-specific differences driving the relationship between measures of HGS and cognitive performance in individuals with hypertension. Full article

The use of Ta/TaN barrier bilayer systems in electronic applications has been ubiquitous over the last decade. Alternative materials such as Co‑W or Ru‑W alloys have gathered interest as possible replacements due to their conjugation of favourable electrical properties and barrier layer efficiency at reduced thicknesses while enabling seedless Cu electroplating. The microstructure, morphology, and electrical properties of Cu films directly electrodeposited onto Co‑W or Ru‑W are important to assess, concomitant with their ability to withstand the electroplating baths/conditions. This work investigates the effects of the current application method and pH value of the electroplating solution on the electrocrystallisation behaviour of Cu deposited onto a Co‑W barrier layer. The film structure, morphology, and chemical composition were studied by X-ray diffraction, scanning electron microscopy and atomic force microscopy, as well as photoelectron spectroscopy. The results show that the electrolyte solution at pH 1.8 is incapable of creating a compact Cu film over the Co-W layer in either pulsed or direct-current modes. At higher pH, a continuous film is formed. A mechanism is proposed for the nucleation and growth of Cu on Co‑W, where a balance between Cu nucleation, growth, and preferential Co dissolution dictates the substrate area coverage and compactness of the electrodeposited films. Full article

Landform classification is important for representing soil physical properties varying continuously across the landscape and for understanding many hydrological processes in watersheds. Considering it, this study aims to use a geomorphology map (Geomorphons) as an input to a physically based hydrological model (Distributed Hydrology Soil Vegetation Model (DHSVM)) in a mountainous headwater watershed. A sensitivity analysis of five soil parameters was evaluated for streamflow simulation in each Geomorphons feature. As infiltration and saturation excess overland flow are important mechanisms for streamflow generation in complex terrain watersheds, the model’s input soil parameters were most sensitive in the “slope”, “hollow”, and “valley” features. Thus, the simulated streamflow was compared with observed data for calibration and validation. The model performance was satisfactory and equivalent to previous simulations in the same watershed using pedological survey and moisture zone maps. Therefore, the results from this study indicate that a geomorphologically based map is applicable and representative for spatially distributing hydrological parameters in the DHSVM. Full article

The use of 3D anthropometric data of children’s heads and faces has great potential in the development of protective gear and medical products that need to provide a close fit in order to function well. Given the lack of detailed data of this kind, the aim of this study is to map the size and shape variation of Dutch children’s heads and faces and investigate possible implications for the design of a ventilation mask. In this study, a dataset of heads and faces of 303 Dutch children aged six months to seven years consisting of traditional measurements and 3D scans were analysed. A principal component analysis (PCA) of facial measurements was performed to map the variation of the children’s face shapes. The first principal component describes the overall size, whilst the second principal component captures the more width related variation of the face. After establishing a homology between the 3D scanned face shapes, a second principal component analysis was done on the point coordinates, revealing the most prominent variations in 3D shape within the sample. Full article

Despite the use of therapeutic ultrasound in the treatment of soft tissue pathologies, there remains some controversy regarding its efficacy. In order to develop new treatment protocols, it is a common practice to carry out in vitro studies in cell cultures before conducting animal tests. The lack of reproducibility of the experimental results observed in the literature concerning in vitro experiments motivated us to establish a methodology for characterizing the acoustic field in culture plate wells. In this work, such acoustic fields are fully characterized in a real experimental configuration, with the transducer being placed in contact with the surface of a standard 12-well culture plate. To study the non-thermal effects of ultrasound on fibroblasts, two different treatment protocols are proposed: long pulse (200 cycles) signals, which give rise to a standing wave in the well with the presence of cavitation (I_{SPTP max} = 19.25 W/cm²), and a short pulse (five cycles) of high acoustic pressure, which produces a number of echoes in the cavity (I_SPTP = 33.1 W/cm², with P_max = 1.01 MPa). The influence of the acoustic intensity, the number of pulses, and the pulse repetition frequency was studied. We further analyzed the correlation of these acoustic parameters with cell viability, population, occupied surface, and cell morphology. Lytic effects when cavitation was present, as well as mechanotransduction reactions, were observed. Full article

In recent years, China has overtaken the United States as the world’s largest carbon dioxide (CO₂) emitter. CO₂ emissions from high-energy-intensive industries account for more than three-quarters of the total industrial carbon dioxide emissions. Therefore, it is important to enhance our understanding of the main factors affecting carbon dioxide emissions in high-energy-intensive industries. In this paper, we firstly explore the main factors affecting CO₂ emissions in high-energy-intensive industries, including industrial structure, per capita gross domestic product (GDP), population, technological progress and foreign direct investment. To achieve this, we rely on exploratory regression combined with the threshold criteria. Secondly, a geographically weighted regression model is employed to explore local-spatial heterogeneity, capturing the spatial variations of the regression parameters across the Chinese provinces. The results show that the growth of per capita GDP and population increases CO₂ emissions; by contrast, the growth of the services sector’s share in China’s gross domestic product could cause a decrease in CO₂ emissions. Effects of technological progress on CO₂ emissions in high-energy-intensive industries are negative in 2007 and 2013, whereas the coefficient is positive in 2018. Throughout the study period, regression coefficients of foreign direct investment are positive. This paper provides valuable insights into the relationship between driving factors and CO₂ emissions, and also gives provides empirical support for local governments to mitigate CO₂ emissions. Full article

In this study, we present a framework for product quality inspection based on deep learning techniques. First, we categorize several deep learning models that can be applied to product inspection systems. In addition, we explain the steps for building a deep-learning-based inspection system in detail. Second, we address connection schemes that efficiently link deep learning models to product inspection systems. Finally, we propose an effective method that can maintain and enhance a product inspection system according to improvement goals of the existing product inspection systems. The proposed system is observed to possess good system maintenance and stability owing to the proposed methods. All the proposed methods are integrated into a unified framework and we provide detailed explanations of each proposed method. In order to verify the effectiveness of the proposed system, we compare and analyze the performance of the methods in various test scenarios. We expect that our study will provide useful guidelines to readers who desire to implement deep-learning-based systems for product inspection. Full article

Pure-phase Cu_2−xS (x = 1, 0.2) nanoparticles have been synthesized by the thermal decomposition of copper(II) dithiocarbamate as a single-source precursor in oleylamine as a capping agent. The compositions of the Cu_2−xS nanocrystals varied from CuS (covellite) through the mixture of phases (CuS and Cu_7.2S₄) to Cu₉S₅ (digenite) by simply varying the temperature of synthesis. The crystallinity and morphology of the copper sulfides were studied using X-ray diffraction (XRD), scanning electron microscopy (SEM), and transmission electron microscopy (TEM), which showed pure phases at low (120 °C) and high (220 °C) temperatures and a mixture of phases at intermediate temperatures (150 and 180 °C). Covellite was of a spherical morphology, while digenite was rod shaped. The optical properties of these nanocrystals were characterized by UV−vis–NIR and photoluminescence spectroscopies. Both samples had very similar absorption spectra but distinguishable fluorescence properties and exhibited a blue shift in their band gap energies compared to bulk Cu_2−xS. The pure phases were used as catalysts for the photocatalytic degradation of tetracycline (TC) under visible-light irradiation. The results demonstrated that the photocatalytic activity of the digenite phase exhibited higher catalytic degradation of 98.5% compared to the covellite phase, which showed 88% degradation within the 120 min reaction time using 80 mg of the catalysts. The higher degradation efficiency achieved with the digenite phase was attributed to its higher absorption of the visible light compared to covellite. Full article

Coffee consumption is gradually increasing in Korea. As a result, interest in the relationship between coffee consumption and various diseases is growing. Several factors affect the development of rheumatoid arthritis (RA), and coffee consumption may be related. We conducted a nationwide cross-sectional study using data from the Korea National Health and Nutrition Examination Survey (2012–2016). A total of 12,465 eligible participants (4819 men and 7646 women) were included in the study. Participants with RA were defined as those who were diagnosed and currently being treated by physicians. Daily coffee consumption amounts were categorized as none, <1 cup, 1–2 cups, 2–3 cups, and ≥3 cups a day based on a self-report. A multivariable logistic regression model was employed, and we calculated the odds ratios (ORs) and 95% confidence intervals (CIs) for the odds of participants having RA with respect to coffee consumption. Compared to the no-coffee group, the ORs for RA in the <1 cup and 1–2 cups groups were 2.99 (95% CI 0.33–27.28) and 2.63 (95% CI 0.31–22.63) in men, respectively, and the ORs for RA for women in the <1 cup, 1–2 cups, 2–3 cups, and ≥3 cups groups were 0.62 (95% CI 0.31–1.26), 0.67 (95% CI 0.33–1.37), 1.08 (95% CI 0.35–3.36), and 1.43 (95% CI 0.25–8.36), respectively. Our study concludes, therefore, that daily coffee consumption is not related to the prevalence of RA in the general Korean population. Full article

Thermophilic Campylobacter species of poultry origin have been associated with up to 80% of human campylobacteriosis cases. Layer chickens have received less attention as possible reservoirs of Campylobacter species. Initially, the minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) of two archived Campylobacter isolates (Campylobacter jejuni strain 200605 and Campylobacter coli strain 200606) from layer chickens to five antimicrobials (ciprofloxacin, nalidixic acid, erythromycin, tetracycline, and gentamicin) were determined using broth microdilution while the presence of selected antimicrobial resistance genes was performed by polymerase chain reaction (PCR) using specific primers. Whole-genome sequencing (WGS) was performed by the Illumina HiSeq X platform. The analysis involved antimicrobial resistance genes, virulome, multilocus sequence typing (MLST), and phylogeny. Both isolates were phenotypically resistant to ciprofloxacin (MIC: 32 vs. 32 µg/mL), nalidixic acid (MIC: 128 vs. 64 µg/mL), and tetracycline (MIC: 64 vs. 64 µg/mL), but sensitive to erythromycin (MIC: 1 vs. 2 µg/mL) and gentamicin (MIC: 0.25 vs. 1 µg/mL) for C. jejuni strain 200605 and C. coli strain 200606, respectively. WGS confirmed C257T mutation in the gyrA gene and the presence of cmeABC complex conferring resistance to FQs in both strains. Both strains also exhibited tet(O) genes associated with tetracycline resistance. Various virulence genes associated with motility, chemotaxis, and capsule formation were found in both isolates. However, the analysis of virulence genes showed that C. jejuni strain 200605 is more virulent than C. coli strain 200606. The MLST showed that C. jejuni strain 200605 belongs to sequence type ST-5229 while C. coli strain 200606 belongs to ST-5935, and both STs are less common. The phylogenetic analysis clustered C. jejuni strain 200605 along with other strains reported in Korea (CP028933 from chicken and CP014344 from human) while C. coli strain 200606 formed a separate cluster with C. coli (CP007181) from turkey. The WGS confirmed FQ-resistance in both strains and showed potential virulence of both strains. Further studies are recommended to understand the reasons behind the regional distribution (Korea, China, and Vietnam) of such rare STs. Full article