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    • Article
    • Open Access

    DroneAVFusion: Towards Drone-Incursion Detection and Classification Using Acoustic–Visual Fusion

    • Sanad Asim Barsiq,
    • Shafíi Nour Iśhak and
    • Shifeng Wang
    • + 3 authors

    The rapid development of small unmanned aerial vehicles (UAVs) has introduced significant challenges in both civilian and defense security domains, such as public safety and protecting critical infrastructure. Detecting and classifying misused drones intruding into low-altitude, cluttered environments remains particularly challenging because of limitations in robust fusion across multiple sensing modalities. Although acoustic and visual fusion has been widely studied, its use for detecting intruding drones has not been sufficiently investigated. This paper proposes DroneAVFusion, a lightweight acoustic–visual fusion pipeline that integrates acoustic and visual sensing via a novel Late Attention Fusion (LAF) mechanism. The proposed system combines a Mel-spectrogram-based convolutional neural network for acoustic detection and optimized YOLO-based visual detection, followed by a computationally efficient fusion module that dynamically weights modalities using confidence-aware gating and temperature-scaled attention. A custom acoustic–visual dataset comprising three commercial drones and non-drone objects is collected and used to evaluate performance under realistic conditions. Experimental results show that DroneAVFusion achieves a 99.6% F1 score on the validation set and perfect performance on the test set while running at an average of 30.40 FPS with only 72,868 parameters in the fusion module. Compared with single-modality baselines and existing fusion approaches, the proposed method demonstrates excellent robustness, making it well-suited for security applications.

    Drones

    27 October 2026

    • Article
    • Open Access

    Fabrication of Superhydrophobic Yogurt Packaging Polymers via Hot Embossing

    • Derrick Emanuel Inhensiko,
    • Khadijah Nakyinsige and
    • Kosmas Ellinas
    • + 4 authors

    Yogurt adhesion to plastic packaging surfaces contributes significantly to product wastage, poor emptiability, and consumer dissatisfaction, which highlights the need for advanced non-stick food packaging solutions. In this study, commercially used yogurt containers made of polypropylene (PP) and low-density polyethylene (LDPE) sourced from Ugandan and Greek markets were engineered into non-stick surfaces through a combination of hot embossing and subsequent hydrophobic coating. Hot embossing successfully transferred hierarchical micro/nano-scale textures onto the polymer surfaces, increasing average surface roughness from 0.79–1.65 µm to 2.27–5.12 µm (p < 0.05), with LDPE exhibiting the highest texture replication. These morphological changes resulted in a marked transition in wetting behavior, with water contact angles (WCAs) increasing from 69.6–100.3° on untreated surfaces to 143.1–160.5° after embossing, accompanied by a significant reduction in contact angle hysteresis (CAH) from 23.9–64.6° to 4.5–23.3°. Subsequent hydrophobic coating further reduced surface free energy, yielding superhydrophobic surfaces with contact angles up to 171.6° and ultra-low hysteresis values as low as 3.6°, consistent with a superhydrophobic wetting state. The combined physical (hierarchical roughness) and chemical (low surface energy) modifications significantly reduced yogurt adhesion and enhanced surface cleanability across all polymers. Bacterial recovery results did not demonstrate antibacterial activity; rather, Teflon™ AF 1600-treated surfaces generally showed higher recoverable viable bacterial counts than untreated surfaces. Principal component analysis further showed associations between surface roughness, water contact angle (WCA), contact angle hysteresis (CAH), yogurt angle (YCA), and recovered bacterial counts. Overall, this work demonstrates a scalable and effective strategy for transforming conventional yogurt packaging into superhydrophobic and non-stick systems, offering a practical pathway toward smart and sustainable dairy packaging with reduced food waste and an improved consumer experience.

    Processes

    27 October 2026

    • Article
    • Open Access

    European policy ambitions and recent legislation have created new opportunities for energy communities (ECs) to expand their role in the energy transition. Such developments are often associated with acceleration processes. As ECs become more established, questions arise as to whether further development can be achieved by initiatives alone or whether it requires stronger forms of collective development. However, ECs often emphasize their local embeddedness. This study examines ECs’ perceived willingness and ability to contribute to collective development by exploring their sense of collectiveness, strategic visions, upscaling ambitions and perceived barriers. Based on interviews with 44 board members of 43 ECs and three intermediary representatives in Groningen, the Netherlands, four types of ECs were identified. Participating ECs differed substantially in their ambitions, orientations and involvement in collective development. Differences in ambitions, local embeddedness, organizational capacity, and future visions appear to complicate collective development and the emergence of a shared strategic vision. The findings indicate multiple pathways through which ECs may respond to conditions associated with acceleration. The study contributes to sustainability transition research by proposing collective development as an extension of network formation and highlighting how differences between ECs may shape their capacity and willingness to contribute to broader societal change.

    Sustainability

    27 October 2026

    • Article
    • Open Access

    This work was conducted to investigate the activity of nanosized zinc oxides in carboxylated nitrile elastomer (XNBR) and natural rubber (NR) under the vulcanization process. Zinc oxide (ZnO) nanoparticles were synthesized by using the sol-gel method and calcination method. Nano-ZnO-substituted NR and XNBR vulcanizates were prepared by varying the loading level of nano-ZnO from 10 phr to 20 phr, 30 phr, 40 phr and 50 phr added to NR and XNBR. The testing specimens of the prepared nano-ZnO-added NR and XNBR vulcanizates were produced through the dipping and drying process. The samples were cut to the required size and standard before being subjected to the tensile test, scanning electron microscopy analysis, and colloidal stability test. ZnO nanoparticles, acting as a curing activator in both NR and XNBR, were found to be more uniformly dispersed in the rubber matrix in comparison with the conventional rubber grade ZnO, as evident from scanning electron microscopy. The tensile strength of NR was observed to be significantly improved as the amount of ZnO nanoparticles was gradually increased up to 50 phr. This indicates that the ZnO nanoparticles can be used as curing activator in NR. For the samples of XNBR, it was also found that further increasing of nano-ZnO amount up to 30 phr significantly improved the tensile strength of XNBR samples. However, subsequent increment of the nano-ZnO amount up to 50 phr did not improve the tensile properties. There was an increase in elongation at break of XNBR vulcanizate with ZnO nanoparticles added. The XNBR vulcanizate showed an optimum performance at 30 phr, which gave the vulcanizates the optimum tensile strength and elongation at break. Meanwhile, for the NR vulcanizate, the addition of 50 phr nano-ZnO was found to provide the optimum effect in term of tensile strength and elongation at break.

    Processes

    27 October 2026

    • Article
    • Open Access

    Ground penetrating radar (GPR) and electrical resistivity tomography (ERT) are increasingly combined for the condition assessment of reinforced concrete, yet published integration schemes generally rely on empirical curve-fitting or qualitative visual overlay rather than on an explicit physical model for the anomaly thresholds applied. This paper presents a forward-modelling programme used to propose provisional, model-informed GPR–ERT screening multipliers and embeds them within a four-stage preliminary risk-screening framework. The multipliers are bracketed by the modelled responses but are not derived from a closed mathematical procedure; the framework is a physics-informed preliminary screening approach, not a validated diagnostic method, and the reported sensitivity results do not constitute statistically validated diagnostic accuracy. A linearised, sensitivity-kernel-weighted (Born-type) formulation was used to compute synthetic Wenner–Schlumberger ERT pseudosections, and a semi-analytical impulse-response superposition (800 MHz Ricker source) was used to compute synthetic GPR radargrams, for four scenarios: an intact reference, a water-filled crack, an air void, and a combined crack–void–corrosion zone. The GPR model reproduces reflection polarities prescribed from electromagnetic theory (R = −0.48 for the water-filled crack mouth; R = +0.52 then −0.52 for the top and bottom interfaces of an air void), which demonstrates implementation consistency rather than independent validation. For the air void, the inverted ERT peak (250–275 Ω·m against a 180 Ω·m background) lies 39–53% above background, which is under 1% of the true resistivity contrast (about 10,000 Ω·m), illustrating the strong under-recovery of high-contrast targets by smoothed, linearised inversion. The modelled responses were used to bracket Stage 2 screening criteria—a GPR rebar-amplitude criterion (A < 0.70 × A0) and ERT conductive/resistive criteria (ρ < 0.60 × ρ0 or ρ > 1.25 × ρ0)—within a four-stage procedure comprising baseline establishment, anomaly screening, spatial cross-validation and indicative risk categorisation. The procedure was applied to previously reported classifications of four masonry field sites, for which no destructive ground truth is available and to which rebar-specific quantities do not directly apply; a preliminary one-at-a-time multiplier sweep of these classifications is under audit and supports no robustness claim. All results derive from a single reference concrete mix, electrode spacing and antenna frequency, and their transfer to other mixes, cover depths and survey geometries has not been tested.

    Buildings

    27 October 2026

    • Article
    • Open Access

    Background: Severe class imbalance hampers mortality prediction in pediatric oncology, where clinical-improvement discharges greatly outnumber deaths and bias standard models toward the majority class. Objectives: We aimed to develop and evaluate a Cost-Sensitive Hybrid Resampling Framework (CSHRF) across recurrent deep-learning architectures to mitigate this bias and improve discharge-outcome classification. Methods: A retrospective cross-sectional study was conducted using electronic health record data from a National Institute of Health in Mexico City during 2023. We analyzed 1607 hospital-discharge records, comprising 1554 clinical improvements and 53 deaths. The CSHRF combines cost-sensitive learning, which amplified the mortality class by a factor of 2.5, with a fixed-seed hybrid resampling protocol embedded in a regularized funnel-shaped architecture (N → N/2 → N/4) trained with gradient clipping (clipnorm = 1.0). Simple Recurrent Neural Network (SimpleRNN), Long Short-Term Memory (LSTM), and Gated Recurrent Unit (GRU) models were compared with a naïve recurrent baseline and standard tabular classifiers (Weighted Logistic Regression, Balanced Random Forest, and XGBoost) using stratified cross-validation. Performance was evaluated using the area under the receiver operating characteristic curve (AUC), G-mean, sensitivity, specificity, precision, F1-score, mean absolute error (MAE), and root mean squared error (RMSE). Results: The naïve baseline showed limited mortality detection (sensitivity 0.150 ± 0.147). The proposed framework substantially improved minority-class detection, with CSHRF-GRU achieving sensitivity of 0.740 ± 0.145, specificity of 0.700 ± 0.076, G-mean of 0.714 ± 0.045, and AUC of 0.761 ± 0.075. Ablation analysis demonstrated that cost-sensitive weighting contributed most substantially to mortality detection, whereas hybrid resampling alone produced more modest gains. Among tabular baselines, Weighted Logistic Regression achieved competitive performance, with sensitivity of 0.684 ± 0.130 and G-mean of 0.767 ± 0.073. Precision remained low (0.079 ± 0.015) and probabilistic calibration errors were substantial (MAE 0.448; RMSE 0.488), reflecting the trade-off required to prioritize mortality detection under severe imbalance. Conclusions: The CSHRF improved discharge-outcome classification in a highly imbalanced pediatric oncology dataset and provides a methodological framework for data-constrained hospital environments. Given its high false-positive rate and probability overestimation, the approach should be interpreted as a discharge-related outcome classification model rather than a standalone clinical decision-support system, and future work should incorporate richer clinical and disease-specific variables to improve predictive performance and calibration.

    Med. Sci.

    27 October 2026

    • Perspective
    • Open Access

    Breast reconstruction is an integral component of comprehensive breast cancer care rather than a merely aesthetic adjunct. For many women, reconstruction is associated with meaningful improvements in body image, psychosocial well-being, and quality of life after mastectomy. Nevertheless, it is not a mandatory part of treatment and represents a preference-sensitive decision. This article presents a clinical perspective, informed by selected literature, clinical guidelines, and institutional practice, on why patients with non-metastatic breast cancer in whom mastectomy is a realistic possibility should be offered reconstructive consultation before surgery. At that stage, reconstructive options remain open, patients have time to reflect, and expectations can be discussed realistically. Counseling should present all legitimate pathways, including implant-based and autologous reconstruction, immediate and delayed timing, the implications of postmastectomy radiotherapy, and no reconstruction with an appropriately planned primary closure. The final plan should be individualized according to oncologic safety, anticipated adjuvant treatment, anatomy, comorbidities, and the surgical burden acceptable to the patient, while also incorporating the patient’s expectations and priorities. Reconstructive consultation should therefore support shared decision-making rather than promote reconstruction, with the final informed choice remaining the patient’s own. Psychological and quality-of-life benefits vary among individuals. The success of early reconstructive involvement should not be measured by reconstruction rates, but by whether patients are able to make informed, realistic, and preference-concordant decisions. We propose a consultation framework addressing oncologic context, reconstructive feasibility, patient priorities, expectation management, treatment decisions, and alternative planning, explicitly including no reconstruction with appropriately planned primary closure when preferred. The framework has not yet undergone formal evaluation.

    • Article
    • Open Access

    A Hybrid Deep Learning Model (CNN-GRU) with MRMR for EEG-Based Depression Detection

    • Mohammad Reza Yousefi,
    • Elias Ebrahimzadeh and
    • Amin Dehghani
    • + 2 authors

    Background/Objectives: Major depressive disorder (MDD) is a prevalent mental health disorder for which objective and reliable diagnostic approaches remain an active area of research. Electroencephalography (EEG) has emerged as a promising non-invasive modality for identifying neural activity patterns associated with depression, while advances in deep learning have enabled effective analysis of complex EEG signals. Methods: In this study, we propose a hybrid deep learning framework that integrates convolutional neural networks (CNNs) for spatial feature extraction and gated recurrent units (GRUs) for temporal modeling of EEG signals. The spatial and temporal features extracted by the CNN and GRU components were concatenated into a 120-dimensional representation, after which minimum redundancy maximum relevance (mRMR) feature selection was applied to reduce redundancy and retain the 30 most informative features before classification. The proposed framework was evaluated using the publicly available MODMA EEG dataset, and its performance was assessed using accuracy, precision, recall, and F1-score. Results: Across 30 independent simulation runs, the CNN–GRU–mRMR framework achieved a mean classification accuracy of 96.74%, exceeding the performance of the comparison methods evaluated in this study. The model also demonstrated high precision, recall, and F1-score, indicating strong classification performance within the evaluated dataset. Conclusions: These findings suggest that integrating spatial and temporal feature learning with mRMR-based feature selection can improve EEG-based depression classification. Further validation using larger, more diverse, and independent clinical datasets is needed to establish the generalizability of the framework and evaluate its potential utility for objective EEG-based depression assessment.

    Diagnostics

    27 October 2026

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Highly Accessed Articles

  • Article
  • Open Access

I argue that the emerging sciences of synthetic morphology and diverse intelligence suggest non-physicalist models of mind and show how they can be empirically investigated. Whence the anatomical, physiological, molecular-biological, and behavioral properties of engineered new beings that have never before existed, and do not have a history of selection? Understanding, predicting, and guiding new forms of life and mind requires characterizing a structured latent space of patterns. Developmental, synthetic, and behavioral biology should take seriously, and exploit, the kinds of non-physicalist ideas that are already a staple of Platonist mathematics. I propose the following hypotheses. (1) Patterns in this space span a highly variable degree of agency, comprising a spectrum ranging from static truths studied by mathematicians to active ones studied by behavioral scientists (i.e., some patterns on the same spectrum as mathematical truths are kinds of minds). (2) The relationship between mind and body is the same as the relationship between causally instructive mathematical facts and physics. (3) Living beings have no monopoly on the “free lunches” provided by the ingression of these patterns into the physical world. While traditional computationalist views of living and cognitive systems are insufficient, my framework erases artificial distinctions between organisms and machines, framing all physical constructs (natural or engineered) as being, to various degrees, in-formed by patterns from the latent space. I sketch a research program, already begun, inspired by these ideas. Such frameworks, while contradicting long-held assumptions of both mechanists and organicists, could have many implications for evolutionary biology, regenerative medicine, AI, and the ethics of synthbiosis with the forthcoming immense diversity of morally important beings.

Philosophies

9 September 2026

76,780 Views
Bodies and minds self-assemble from single cells as a process of alignment and autopoiesis. (A) Most complex biological forms begin as one cell—a fertilized oocyte, commonly thought to be well-described by the laws of physics and chemistry. (B) A gradual, slow process of developmental morphogenesis results in the final form of the organism, which may have complex structure and a mind which may not believe it is a “machine”. Our transformation from a chemical soup into an active embodied mind is continuous but heterogeneous: (C) while we commonly think of ourselves as a unified intelligence with a “centralized” brain, the fact is that even the pineal gland, of which there is only one in the brain, is made of cells (C′) and those cells in turn are made of myriad other active components (C″)—we are a collective intelligence at all scales. (D) The creation of an “individual” out of an excitable medium such as an embryonic blastoderm with hundreds of thousands of cells is a dynamic process that is not hardwired: scratches made in that blastoderm would result in independent self-organization in each island, resulting in multiple embryos forming. This reveals the potentiality for some non-pre-determined number of minds to arise out of the same substrate. Images in (A,B,D) courtesy of Jeremy Guay of Peregrine Creative, used previously in [29]. Image (B) used with permission from [30]. Image in (C′) courtesy of Jose Calvo, Science Photo Library. Image in (C″) courtesy of Evan Ingersoll and Gaël McGill. Image (D) used with permission from [31].
  • Article
  • Open Access

Digital Facial Approximation of Jebel Irhoud Composite Skull (~315,000 BP)

  • Cicero Moraes,
  • Elena Varotto and
  • Johari Yap Abdullah
  • + 3 authors

The archeological site of Jebel Irhoud, Morocco, houses the oldest fossils attributed to Homo sapiens, dated to approximately 315,000 years before present (BP). This study presents a forensic facial approximation based on data from a three-dimensional composite skull derived from Layer 7 of the site, with structural predominance of the Irhoud 1 fossil. The methodology employed open-source software tools, combining anatomical projections and the constrained anatomical deformation technique. Endocast segmentation yielded a volume of 1364 mL, a result fully compatible with measurements and segmentations obtained in previous studies directly from the fossil, while also aligning with the variation observed in modern populations. Two sets of images were produced: an objective approximation in grayscale, focused on osteological correspondence, and a colored artistic version featuring skin pigmentation and facial hair for scientific communication. The results reinforce the feasibility and reproducibility of open-access methodologies applied to paleoanthropology, offering an anatomically coherent representation of this Middle Pleistocene hominin.

Heritage

13 September 2026

18,245 Views
(A) Photogrammetry performed from video (credit: Philipp Gunz, MPI EVA Leipzig, License: CC-BY-SA 2.0). (B) One of the scale adjustments based on images of the findings. (C) Adjustment of the virtual donor to the endocranial structure (credit: Philipp Gunz, MPI EVA Leipzig, License: CC-BY-SA 2.0). (D) Segmentation of the endocranium from the anatomical deformation of the virtual donor. References available in [3].
  • Review
  • Open Access

Background: Chlorine dioxide (ClO2), formulated as an aqueous solution (CDS), has been proposed as a therapeutic agent, yet its classification among oxidizing compounds is frequently confounded with chemically distinct species—sodium chlorite (NaClO2) and sodium hypochlorite (NaOCl). Objective: This study aimed to synthesize the physicochemical, mechanistic and cellular basis of ClO2 action and to delineate the distinctions between ClO2 and related oxidants, with explicit separation of established data from hypothesized data. Methods: The methodology includes a narrative synthesis of electrochemical data, primary toxicological and clinical literature (PubMed) and the redox-biology literature on low-dose oxidant signaling. Results: ClO2 is a neutral free radical that acts via one-electron transfer (E°′ = +0.95 V vs. SHE for the half-reaction ClO2 + e− → ClO2−, essentially pH-independent over pH 4–8, pH-independent) without chlorination. Its antimicrobial action is attributable to oxidation of thiol-dependent enzymes and membrane constituents and to the inhibition of bacterial respiratory metabolism; host-cell sparing is consistent with differential glutathione-dependent buffering. Controlled human ingestion studies at low concentrations report a favorable short-term safety profile; conversely, the principal metabolite (chlorite) is associated with documented developmental toxicity in animals and regulatory caution by EPA/WHO. Low-dose ClO2 exposure is hypothesized—but not yet directly demonstrated—to elicit dose-dependent adaptive redox responses and redox-regulatory modulation. Conclusions: The one-electron, non-chlorinating chemistry of ClO2 provides a coherent mechanistic framework. The translation of this framework into clinical application requires prospective trials and direct mechanistic measurement, ideally conducted by independent investigators. The following mechanisms are hypothesized and have not yet been directly demonstrated in vivo: modulation of oxidative phosphorylation, mitochondrial oxygenation, and associated redox-regulatory signaling. Reported antimicrobial efficacy typically occurs in the low-ppm range (0.1–5 ppm), whereas adverse effects on mammalian cells in the reviewed literature are reported at concentrations at least one order of magnitude higher; direct head-to-head cytotoxicity comparisons remain scarce and are identified as a priority for future work. This differential thiol buffering—in particular, the higher glutathione content of many mammalian cells relative to many pathogens—has been proposed as a contributing basis for host-cell sparing; direct quantitative confirmation in vivo is not yet available. Bacterial species possess their own thiol-based defense systems (e.g., mycothiol in actinomycetes, bacillithiol in Firmicutes), and the interplay between ClO2 and these systems requires further investigation.

Biophysica

21 September 2026

13,053 Views
Mechanistic overview. ClO2 acts via one-electron oxidation of microbial targets (thiol oxidation, envelope and nucleic acid damage, respiratory inhibition); host cells are spared through glutathione-dependent redox buffering. The proposed low-dose hormetic response is a hypothesis requiring direct experimental confirmation, as discussed in Section 4.2.
  • Article
  • Open Access

Nanoconfinement-Enhanced CO2 Retention in Fenamate-Loaded Silica Aerogels

  • Konstantin Belov,
  • Maria Ikim and
  • Ilya Khodov
  • + 6 authors

The interaction between carbon dioxide and molecularly confined pharmaceutical compounds can result in CO2 retention that exceeds that achieved through conventional physical adsorption. This study investigates CO2 retention following sorption in hydrophilic and hydrophobic silica aerogels containing the fenamates mefenamic acid and flufenamic acid. The Thermal stability of the retained CO2 was characterized using temperature-programmed oxidation and temperature-programmed desorption measurements. Concurrently, single-point nitrogen adsorption measurements monitored relative changes in the apparent accessible surface area of the porous matrix. Untreated silica aerogels did not exhibit a significant CO2 desorption peak at elevated temperatures. In contrast, all composites containing fenamates exhibited an additional high-temperature desorption step beginning at approximately 225 °C, indicating enhanced CO2 retention after sorption once the external CO2 layer was removed. This characteristic persisted following preliminary thermal treatment, suggesting it is not solely attributable to residual volatile substances. Surface-area measurements indicated minimal changes in the original aerogels after the CO2 cycle, whereas composites with flufenamic acid demonstrated more pronounced alterations. Considering previous nuclear magnetic resonance, spectroscopic, and computational studies, these findings suggest a combined effect of nanoconfinement, surface-dependent interfacial phenomena, and specific interactions involving the fenamate-containing phase. Reversible chemical interactions may contribute to the observed retention, although the current measurements do not allow for quantitative separation of their effects from those of physical confinement.

Molecules

14 September 2026

13,073 Views
TPO (black) and TPD (red) curves for AG-H-Phil (a) and AG-H-Phob (b) recorded over the temperature range from 30 °C to 500 °C.

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Editor's Choice Articles

  • Review
  • Open Access

Cistus creticus, a perennial shrub native to the Mediterranean region, has attracted considerable scientific attention due to its rich phytochemical profile and associated health-promoting properties. This review provides a comprehensive analysis of the antioxidant activity of C. creticus, examining the various extraction methods that influence the bioavailability and efficacy of its active compounds. The plant’s antioxidant properties are primarily attributed to its high content of flavonoids, phenolic acids, and other bioactive constituents, which play a key role in mitigating oxidative stress and reducing the risk of chronic diseases. The review further discusses the effectiveness of different extraction techniques—mainly maceration and ultrasound-assisted extraction—in maximizing the yield and potency of antioxidants from the plant. By synthesizing current research findings, this review aims to highlight the therapeutic potential of C. creticus and provide a basis for future studies on its application in nutraceuticals and functional foods.

AppliedChem

2 October 2026

Conceptual overview of extraction methods, polyphenolic classes, biological activities, and food applications of Cistus creticus extracts.
  • Review
  • Open Access

Technology-mediated sexual behaviours, including cybersex and technosex, are becoming increasingly prevalent as digital technologies, virtual reality, artificial intelligence, and interactive devices continue to develop. Although these behaviours may offer numerous benefits, such as facilitating sexual exploration, supporting individuals with disabilities, and enabling long-distance intimacy, they may also contribute to problematic patterns of use in some individuals. This review synthesises current knowledge on the psychological and neurobiological mechanisms underlying cybersex and technosexual behaviour. The article discusses conceptual and definitional issues, epidemiological data, and theoretical frameworks, including the Triple A model and the “quasi-necrophilia” framework, to explain the characteristics and motivations behind technology-mediated sexual activities. Furthermore, it summarises psychological factors associated with both adaptive and maladaptive use, emphasising the role of emotion regulation, personality traits, neurodevelopmental conditions, mental health, and sexual motivations. The review also presents current evidence on the neurobiology of cybersex and technosex, highlighting the involvement of dopaminergic reward pathways and similarities to other reward-related behaviours. Finally, available approaches to the treatment of problematic technology-mediated sexual behaviour are discussed, including pharmacotherapy, as well as psychoeducation and psychotherapy, with particular attention to the importance of addressing underlying psychological conditions. The article argues that cybersex and technosex should not be inherently pathologised—instead, they should be understood within a biopsychosocial framework that distinguishes between healthy sexual expression and clinically significant impairment.

Brain Sci.

9 October 2026

  • Review
  • Open Access

Wearable and attachable healthcare devices provide valuable insights across a broad range of applications, from health monitoring and disease diagnosis to the assessment of daily human activities. For these devices, both the formation of high-performance electrodes and mechanical, electrical, and physiological stability at human-device interfaces are critically important. Conductive gels, which combine deformable polymer networks with electrical conductivity, show considerable potential as functional materials for such applications. However, existing reviews have often considered material properties, interfacial behavior, and device reliability separately. This review examines hydrogels, ionogels, and organogels by linking material design, stimulus- and analyte-responsive sensing, biological and device interfaces, and healthcare applications. This integrated perspective emphasizes evaluating conductive gels within complete healthcare devices, where material properties, biological interfaces, and device integration jointly determine practical performance. Such evaluation needs to address signal quality and the stability of the assembled system during deformation, environmental exposure, and prolonged use. Future progress will require reproducible device fabrication and standardized validation tailored to the intended application, with systematic assessment of long-term biosafety and alignment with relevant regulatory requirements. Integration with flexible electronics, intelligent data processing, and feedback control may further enable reliable and responsive healthcare platforms.

Gels

30 September 2026

  • Review
  • Open Access

Accelerating the low-carbon transition of transport is essential to addressing global climate change. Although the rapid growth of the electric vehicle (EV) fleet highlights the environmental benefits of electrified mobility, carbon-intensive upstream electricity generation and energy-intensive battery production continue to constrain the life-cycle emissions reduction potential of EVs. Focusing on China, this structured narrative review examines 121 core references from 2004 to 2026 to synthesize carbon-accounting methods and emissions across the manufacturing, use, and end-of-life stages. A supplementary keyword co-occurrence analysis of 1180 Web of Science records provides an overview of the research field. The reviewed evidence indicates that embodied emissions from manufacturing account for more than 30% of total life-cycle emissions, making this stage important to life-cycle decarbonization. The use stage offers the greatest emissions reduction potential and is closely linked to regional grid carbon intensity and vehicle-to-grid (V2G) scheduling. At the end of life, second-life battery use and closed-loop recycling can reduce the burden associated with initial production and support material circularity. Drawing on these findings and the development of China’s EV industry, this review proposes decarbonization pathways for enterprises and policymakers to support the coordinated development of the transport and energy sectors.

World Electr. Veh. J.

30 September 2026