1,817,558 Results Found

Background: Dulaglutide, a GLP-1-IgG4 Fc fusion, is a long-acting GLP-1 receptor agonist used for type 2 diabetes therapy and other emerging indications. It is produced commercially in Chinese hamster ovary (CHO) cells. The supply of the original dru...

Recently, the installed generation capacity of wind energy has expanded significantly, and the doubly fed induction generator (DFIG) has gained a prominent position amongst wind generators owing to its superior performance. It is extremely vital to e...

This research focuses on the additional valorization of olive leaves, a by-product of regular olive pruning, by increasing their secondary metabolite content through the combined application of biochar and a phenolic extract from olive leaves. A susp...

This study presents a decision tree model-based approach to classify rural net migration across Colombian departments using sociodemographic and economic variables. In the model formulation, immigration is considered the movement of people to a desti...

Public attitudes toward renewable energy sources (RES) have been widely studied at the household level. However, less is known about how citizens differ in their broader perceptions, knowledge, and behavioral orientations toward renewable energy. Thi...

Microtopography regulates soil erosion by shaping surface heterogeneity, but the mechanism of loess slope soil loss remains insufficiently quantified. This study combined laboratory rainfall simulations and machine learning to investigate how tillage...

Human Papillomavirus (HPV)-related cancers constitute a major global health problem, accounting for 4.5% of all human cancers. Studying the composition of the tumor microenvironment (TME) of HPV-related cancers may help develop therapeutic strategies...

Sedimentary dynamics in the Palamós Canyon are influenced by river inputs and storm resuspension, as well as by bottom trawling on the canyon flanks. In this study, we estimate recent sediment deposition patterns along the canyon axis using th...

Background: This retrospective matched-pair analysis compared functional outcomes and complications of prostate artery embolization (PAE) using 250 µm microparticles and holmium laser enucleation of the prostate (HoLEP) in patients with lower u...

Growing EV adoption is reshaping how Distributed Energy Resources (DERs) interact with the grid, playing a pivotal role in global decarbonization efforts and the transition towards a sustainable energy future. This study built a Virtual Power Plant (...

This work focuses on finding frequent patterns in continuous flow network traffic Big Data using incremental frequent pattern mining. A newly created Zeek Conn Log MITRE ATT&CK framework labeled dataset, UWF-ZeekData24, generated using the Cyber...

This paper examines the effects of AI-based digital nudges on consumers’ sustainable purchase intentions and behaviors, using an integrated framework that combines the Technology Acceptance Model (TAM) and the Nudge Theory. Previous studies hav...

Colorectal cancer (CRC) remains the third leading cause of mortality among cancer patients in developed countries. Each new study in this field can contribute to better detection, diagnosis, and treatment of this disease. Our study aimed to assess tr...

Taking a large single-phase generator transformer product as the research object, this paper applied the finite element simulation method to analyze the vibration characteristics of its core. Firstly, through the analysis of vibration theory, the vib...

Eel (Anguilla) is an aquatic animal with high nutritional value and multiple health benefits for the human body. To fully utilize its processing by-products fish bone, this study optimized the enzymatic preparation process of using BP neural network...

It is well known that food waste, especially perishable fruits, is one of the pressing issues worldwide, and as much as 50% of harvested fruits are wasted in developing countries as a result of poor preservation methods. Other traditional options suc...

A novel mesoporous spherical chelating lignin-based adsorbent was successfully synthesized via inverse suspension polymerization using sulfate pine pulping black liquor as raw material, followed by graft copolymerization with acrylonitrile and subseq...

Silicon carbide (SiC) three-phase converters are widely adopted in parallel power distribution systems for their high efficiency, yet their performance is challenged by high switching frequency and communication constraints. For the parallel inverter...

This study proposes an intelligent surveillance framework that integrates image preprocessing, illuminance-adaptive object detection, multi-object tracking, and pedestrian abnormal behavior recognition to address the rapid degradation of image recogn...

Eutrophication has emerged as a critical threat to water quality degradation and ecosystem health on a global scale, calling for prompt management actions. Remote sensing enables the monitoring of eutrophication by detected changes in ocean color cau...

To address the synergistic stability evaluation of coal pillars and caving deposits in room-and-pillar mining of nearly vertical coal seams, this study takes the 101 Coal Mine (104th Regiment, Xishan Area, Urumqi, Xinjiang) as the engineering backgro...

Background/Objectives: Thyroid hormones (THs) regulate almost all physiological processes in vertebrates via specific mechanisms exercised spatiotemporally throughout the lifespan. The TH signalling can be impaired by thyroid-disrupting chemicals (TD...

La-doped ZnO nanoclusters confined within mesoporous SBA-15 were synthesized using an impregnation–calcination method and evaluated for their visible-light-driven photocatalytic degradation of Rhodamine B (RhB). Small-angle X-ray diffraction (X...

Big data and artificial intelligence technologies are driving a paradigm shift in smart farming, yet intelligent decision-making faces critical bottlenecks. At the data level, challenges include fragmentation, high acquisition costs, and inadequate s...

Accurate detection of concealed items in X-ray baggage images is critical for public safety in high-security environments such as airports and railway stations. However, small objects with low material contrast, such as plastic lighters, remain chall...

The role of LAP proteins expressed in skeletal muscles (ERBIN, LANO, and SCRIBBLE) and at neuromuscular junctions (NMJs) remains largely unknown. Our previous data demonstrate that LAP proteins are differentially expressed in muscle cells, nerve endi...

Infants and children with congenital heart diseases (CHDs) are especially susceptible to malnutrition. The pathogenesis of nutritional disorders in this population reflects a multifactorial balance between increased metabolic demands, reduced dietary...

Brainwave entrainment (BWE) through Binaural Beats (BBs) has been proposed as a non-invasive method to modulate cortical activity by enhancing oscillatory power at specific frequencies. Despite growing interest, empirical evidence regarding the effic...

Background: Impaired bone health is a recognized complication of type 1 diabetes. This study evaluated the effects of low-carbohydrate (LC) and Mediterranean (MED) diets on bone turnover markers in adolescents and young adults. Methods: In a 24-week...

FeCoNiCu(Cr, Mn, La, Ce)-Al high-entropy alloys (HEAs) were prepared via a combined centrifugal casting–self-propagating high-temperature synthesis process to serve as multifunctional catalyst precursors. The findings indicated that even with a...

This study evaluated the effects of a passive upper-limb exoskeleton in agricultural work using a repeated-measures design with 24 adult males across three exoskeleton conditions (No Exo, Prototype, and Airframe), three work directions (left, front,...

Severe aortic stenosis represents a significant prognostic burden, particularly in symptomatic patients. The advent of transcatheter aortic valve replacement (TAVR) has revolutionized the treatment of patients previously considered ineligible for sur...

Astrocytes, long viewed as passive support cells, are now recognized as dynamic regulators of synaptic function. This mini review summarizes recent findings revealing that astrocyte leaflets, thin peripheral processes of astrocyte, form gap junction...

In this paper, we introduce and investigate two generalized forms of classical contraction mappings, namely the p-Hardy–Rogers and p-Zamfirescu contractions. By incorporating the integer parameter p≥1, these new definitions extend the tradit...

Background: Field hockey is a high-intensity intermittent sport, where nutrition and sleep play an important role in the performance and health of all players, especially in women, who often exhibit a dietary pattern characterized by low energy and c...

Against the backdrop of growing climatic variability, the identification of genotypes combining high yield with stability and resilience to stress factors has become a central objective of contemporary wheat breeding. Therefore, the objective of this...

(1) Background: Female homelessness is one of the most invisible forms of social exclusion, aggravated by structural and gender factors and by experiences of violence. This research analyzes the multifaceted barriers hindering women experiencing home...

In the current digital competition environment, e-commerce platforms have increased their investment in targeted advertising, improving advertising efficiency while also influencing the choice of product sales modes. This study aims to deeply explore...

Two-dimensional materials and their van der Waals heterostructures have shown great potential in quantum physics, flexible electronics, and optoelectronic devices. However, interfacial bubbles originated from trapped air, solvent residues, adsorbed m...

Tomato (Solanum lycopersicum L.), one of the most widely consumed horticultural crops worldwide, is also a notable source of food allergens, with a higher prevalence of allergic reactions in pollen-sensitized patients. Profilin, a small actin-binding...

Background: The development of CAD, FEA, and biomechanical models of the shoulder is challenging due to the joint’s complexity. The spatial relationships between bones, muscles and ligaments are difficult to parameterize, both statically and dy...

Aircraft turnaround efficiency is a key determinant of the sustainability of air transport systems. Each stage of ground handling—passenger disembarkation, baggage handling, refuelling, and ancillary services—contributes to the total turn...

Critical thinking, regarded as an indispensable high-order thinking for pre-service teachers, is of great significance in effective teaching and the cultivation of students’ critical thinking. Given that it has been confirmed by previous studie...

Coal gangue, a major industrial solid waste from coal mining and processing, requires efficient alumina and silica separation for high-value utilization. This study focused on mineral reaction mechanisms and characteristics of coal gangue during calc...

Background: The global incidence of dengue has markedly increased over the last decades. Consequently, the risk of infection has increased significantly, resulting in record numbers of imported cases in various European countries and elsewhere in 202...

Background/Objectives:Disorganization of the retinal inner layers (DRIL) is an important biomarker of diabetic macular edema (DME) that has a very strong association with visual acuity (VA) in patients. But the unavailability of annotated training da...

Novel adjuvants are key to making allergen-specific immunotherapy (AIT) safer and more effective. Their development is crucial for moving AIT into a new generation of precision medicine. N-glycosylation of protein antigens plays a pivotal role in mod...

With the advancement of new power systems, phase-change materials (PCMs), owing to their ability to convert and store electrical energy, are increasingly recognized as a key solution to the intermittency of power supply. Nevertheless, such materials...

Emergency scenarios in the Internet of Vehicles (IoV) face significant challenges due to the stringent requirements for ultra-reliable and low-latency communication under high-mobility conditions. This paper proposes a cooperative transmission framew...

Background: Providing complex care and support for people with technology dependence (PwTD) is challenging, even under routine conditions. During disasters, when health and power infrastructure are disrupted, the complex care of PwTD must be maintain...