- Article
High-Resolution 1H NMR Investigation of the Speciation Status of Nickel(II) and Copper(II) Ions in a Cell Culture Medium: Relevance to Their Toxicological Actions
- Deepinder K. Kalra,
- Kayleigh Hunwin,
- Katie Hewitt,
- Olivia Steel and
- Martin Grootveld
24 December 2025
Copper and nickel ions play pivotal, albeit distinct, roles as essential trace elements in living systems, and primarily serve as co-factors for a range of enzymes. However, as with all trace metal ions, excessive concentrations can exert adverse tox...