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Proteomes, Volume 14, Issue 1

2026 March - 7 articles

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Articles (7)

  • Article
  • Open Access

PTMs_Closed_Search: Multiple Post-Translational Modification Closed Search Using Reduced Search Space and Transferred FDR

  • Yury Yu. Strogov,
  • Sergey A. Spirin,
  • Mark V. Ivanov,
  • Maria A. Kulebyakina,
  • Anastasia Yu. Efimenko and
  • Oleg I. Klychnikov
Proteomes2026, 14(1), 7;https://doi.org/10.3390/proteomes14010007 
(registering DOI)

2 February 2026

Background: Currently, post-translational modification (PTM) search in MS/MS data is performed using either open modification search (OMS) or closed search (CS) algorithms. The OMS method allows for the determination of many PTMs and unknown mass-shi...

  • Article
  • Open Access
186 Views
31 Pages

Evaluating the Impact of Two Different Diets on the Protein Profile of the Brain, Liver, and Intestine of the Barramundi

  • Mohadeseh Montazeri Shatouri,
  • Igor Pirozzi,
  • Pinar Demir Soker,
  • Zeshan Ali,
  • Ardeshir Amirkhani and
  • Paul A. Haynes

Background: Commercial feed formulations are increasingly being evaluated for their nutritional impacts on aquaculture species, yet the molecular consequences of commonly used commercial diets remain underexplored. Methods: This study investigated th...

  • Article
  • Open Access
92 Views
23 Pages

Background: Cleft palate (CP) is a prevalent craniofacial malformation, with the TGFβ pathway playing a critical role. Recent evidence links autophagy to regulating mouse embryonic palatal mesenchyme (MEPM) cells, but its interaction with TGF&be...

  • Article
  • Open Access
213 Views
21 Pages

Cross-Species Analysis of ABA-Induced Phosphosignaling Landscapes in Rice, Soybean, and Arabidopsis

  • Hinano Takase,
  • Sotaro Katagiri,
  • Takuma Ide,
  • Aina Nagano,
  • Haruki Sakurai,
  • Hana Kokubo,
  • Taiki Yanagisawa,
  • Masanori Okamoto and
  • Taishi Umezawa

Background: Abscisic acid (ABA) is a key phytohormone that regulates plant growth and stress responses through protein phosphorylation. While ABA-induced phosphosignaling has been extensively studied in Arabidopsis thaliana, its conservation and dive...

  • Article
  • Open Access
537 Views
28 Pages

The Proteome of Dictyostelium discoideum Across Its Entire Life Cycle Reveals Sharp Transitions Between Developmental Stages

  • Sarena Banu,
  • P. V. Anusha,
  • Pedro Beltran-Alvarez,
  • Mohammed M. Idris,
  • Katharina C. Wollenberg Valero and
  • Francisco Rivero

Background: Dictyostelium discoideum is widely used in developmental and evolutionary biology due to its ability to transition from a single cell to a multicellular organism in response to starvation. While transcriptome information across its life c...

  • Article
  • Open Access
286 Views
16 Pages

Proteomics and Bioinformatics Profiles of Human Mesothelial Cell Line MeT-5A

  • Rachel L. Watkin,
  • Avedis A. Kazanjian,
  • Jennifer R. Damicis and
  • Elizabeth Yohannes

Background: Despite existing proteomics studies of other cell types, a comprehensive proteome of mesothelial cells has not been characterized. This study establishes a crucial baseline proteome for mesothelial cells to better understand their fundame...

  • Article
  • Open Access
243 Views
20 Pages

Beyond Repression: ArsR Functions as a Global Activator of Metabolic and Redox Responses in Escherichia coli

  • Brett Sather,
  • James Larson,
  • Kian Hutt Vater,
  • Jade Westrum,
  • Timothy R. McDermott and
  • Brian Bothner

Background: The arsenic-responsive repressor, ArsR, has long been understood as a canonical regulator of the arsRBC operon, which confers resistance to arsenic stress. However, recent studies suggest a broader regulatory scope for ArsR. Here, we inve...

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Proteomes - ISSN 2227-7382