1,854,754 Results Found

Sustainability has become a central pillar of public policy and higher education, with university students playing a key role both as recipients of knowledge and as agents of change toward more responsible practices. Existing literature shows that st...

With the increasing emergence of multidrug-resistant (MDR) bacteria, there is an urgent need to discover new antibiotics. In this study, genome mining coupled with anti-bacterial assay guided the targeted isolation of two new heptapeptides nobilamide...

Mastitis is a prevalent disease in the dairy cattle industry and has adverse effects on dairy cows’ health and milk quality. Importantly, mastitis is associated with the inflammatory response and mitophagy. As a complement-regulatory factor, C4...

The residential building sector is a significant source of global energy consumption and carbon emissions, especially in rapidly changing rural areas. In China, the shift from vernacular courtyard dwellings to modern rural housing has altered the rel...

The goals of ulcerative colitis (UC) treatment are focused on improving quality of life, achieving steroid-free remission, and minimizing the risk of cancer. In UC traditional management, a step-up strategy involves introducing increasingly more immu...

Sorting networks are of prime importance as circuits, with applications in sorting small data chunks, big data analytics, permuting packets, and system interconnects. Finding optimal sorting networks is a highly complex problem, and knowledge on opti...

Eutrophication is a form of pollution caused by elevated nutrient concentrations in water bodies, leading to excessive algal growth and subsequent oxygen depletion. This process poses significant risks to aquatic ecosystems and overall water quality....

A point-of-care (POC) HIV drug resistance (HIV-DR) test is needed for low- and middle-income countries (LMICs). Oligonucleotide Ligation Assay (OLA)-Simple, designed as a near-POC HIV-DR test, was assessed for its overall usability in Kenya by techni...

Background: Augmented reality (AR) and mixed reality (MR) promise to enhance anatomical understanding, spatial orientation, and workflow in cardiac surgery. Their clinical adoption remains limited and the translational path is incompletely defined. M...

Under the dual imperatives of environmental protection and sustainable socio-economic development, the high energy consumption of the manufacturing sector has become a significant barrier to its transition toward industrial ecological transformation....

Background/Objectives: Upper respiratory tract infections (URTIs) and exercise-induced immune perturbations are common in adults and may adversely affect quality of life, productivity, and physical performance. Immunoglobulin Y (IgY), a food-derived...

Accurate prediction of post-construction settlement in high-speed railway (HSR) soft foundations is critical for operational safety yet challenging due to the non-equidistant and non-stationary nature of observation data. This study systematically ev...

Severe respiratory inflammation or viral infections can lead to acute lung injury (ALI), a disease characterized by diffuse inflammatory injury of the pulmonary epithelium and endothelium. Cepharanthine (CEP) is reported as a promising drug candidate...

Background/Objectives: Home Enteral Nutrition Therapy (HENT) is widely used for patients with preserved gastrointestinal function who cannot maintain adequate oral intake. It can be administered through commercial formulas (CF) or artisanal preparati...

As a source of non-protein nitrogen, ammonium chloride (NH₄Cl) is widely utilized in ruminant diets to reduce feed costs. However, the impact of its supplementation level on the flavor of sheep meat remains unclear, despite the known influence of fat...

L-theanine is a bioactive non-protein amino acid predominantly derived from tea plants (Camellia sinensis), widely recognized for its potential benefits in mood regulation and psychological health. Despite its promising neuropsychological profile, th...

Adolescent tobacco use remains a critical public health challenge, requiring innovative early prevention strategies. This study participatively evaluated a medium-fidelity prototype of the No le entres app, designed to prevent tobacco use among adole...

This study investigates the synergistic effects of an electropulsing (EP) and ultrasonic impact treatment (UIT) hybrid process on the mechanical and corrosion properties of D36 low-carbon steel. Conventional UIT has been shown to enhance surface hard...

Human sexual development begins in the prenatal period and continues throughout life, shaped by both biological and psychosocial factors. Somatic development leads to reproductive maturity through several stages regulated by the hypothalamic–pi...

Objectives: This study aimed to evaluate auditory cortical maturation in pediatric cochlear implant (CI) users using speech-evoked cortical auditory evoked potentials (CAEPs) and to compare P1 latency responses with age-matched normal-hearing (NH) pe...

Mining is undergoing a transformation driven by digitalisation and automation, promising improvements in efficiency, sustainability, and safety [...]

The tumor microenvironment plays a critical role in cancer progression, with oxidative stress, autophagy, angiogenesis, and cell migration acting as tightly interconnected processes. Natural bioactive compounds have emerged as promising modulators of...

Background/Objectives: Methotrexate (MTX) is a cornerstone drug used to treat immune-mediated inflammatory diseases (IMIDs) in low doses (10–30 mg/week), and malignancies in high doses (5000 mg/m²/2 weeks). Its active metabolites, Methotrexate...

Bone regeneration in critical-size defects requires biomaterials that provide both structural support and appropriate osteoinductive cues. Natural nacre contains an organic matrix rich in acidic macromolecules with reported osteogenic activity; howev...

Background: Tobacco smoke exposure in the home remains common among U.S. families and has been increasingly associated with adverse mental health outcomes, including anxiety and depression, among children and adolescents. Rising rates of youth anxiet...

This study focused on the incorporation of Piper betle L. essential oil (EO) into β-cyclodextrin (β-CD) and the subsequent incorporation of this complex into chitosan-based films with a beeswax coating. The objective of this study was to de...

Catalytic pyrolysis is a crucial technology for lignin valorization, where the catalyst support itself can play a pivotal role in influencing the catalytic process. This study systematically investigates and compares the distinct catalytic effects of...

Environmental exposures are increasingly recognized as important drivers of ocular surface inflammation, yet their combined contribution to the onset, exacerbation, and clinical burden of allergic conjunctivitis (AC) has not been comprehensively synt...

Introduction: Minimally invasive pancreatoduodenectomy (MIPD), including laparoscopic (LPD) and robotic approaches (RPD), has gained increasing attention as an alternative to open pancreatoduodenectomy (OPD). Despite rapid technological progress, con...

The digital era represents a paradigm shift in gifted education, moving at an accelerating pace away from traditional models toward flexible and personalized technology-based pathways. This study investigates the impact of a model implemented via the...

Background: Robot-assisted partial nephrectomy (RAPN) can be done using either a three-arm or four-arm configuration. However, the evidence comparing the perioperative, functional, and oncological outcomes between these two approaches is inconsistent...

Serrated adenocarcinoma (SAC) represents a molecularly heterogeneous subtype of colorectal carcinoma (CRC) linked to the serrated pathway. It is aimed to clarify the molecular mechanisms underlying SAC development. Digital slides from The Cancer Geno...

The Group-1 carcinogen Helicobacter pylori (H. pylori) secretes the serine protease high-temperature requirement A (HtrA), which is directly involved in the disruption of the epithelial barrier in the stomach. HtrA cleaves the extracellular domains o...

Extreme natural disasters raise a fundamental question for biologically rigid food production systems: does post-disaster productivity recovery stem from technological change or from adaptive reorganization within existing constraints? In inland aqua...

This study presents an integrated modeling and optimization framework for laser transmission welding (LTW) of transparent polymethyl methacrylate (PMMA) joints using single- and multi-core copper wires as energy absorbers. The highly nonlinear relati...

This study evaluates the performance of a flat-plate solar collector thermal system located in Bucharest, Romania, by combining experimental measurements (December 2024–April 2025) with numerical modeling. The system, coupled to a 4000 L tank a...

Background and Aim: The management of patients with chronic Hepatitis B Virus (HBV) HBeAg-negative infection in the indeterminate-grey zone (GZ) remains debatable. We conducted a systematic review and meta-analysis to compare these patients with thos...

We investigate the multi-layer atmospheric impacts of Typhoon Hagibis (2019), which formed on 6 October, tracked across 12–35${}^{\circ }$ N and 135–155${}^{\circ }$ E, and made landfall on 12 October over the Izu Peninsula, central Honshu, Japan. We...

Background: Depression is a common mental disorder, and early and objective diagnosis of depression is challenging. New advances in deep learning show promise for processing audio and video content when screening for depression. Nevertheless, the maj...

Background: Oedema is a multifactorial condition arising from the interplay between increased microvascular permeability, impaired lymphatic clearance, and sustained inflammation. Conventional treatments often fail, highlighting alternative therapies...

Several Fusarium species have demonstrated the ability to thrive in saline soils and to tolerate or prefer high salt concentrations. In this context, the potential halophilic or halotolerant lifestyle of Fusarium pseudograminearum was investigated. F...

Pesticides are applied to promote performances in the agricultural field, sustaining crop productivity by counteracting the damages induced by pests and weeds. Under conditions of uncontrolled application, their negative influences exerted on soil, w...

With the advancement of task-oriented reinforcement learning (RL), the capability of quadruped robots for motion generation and complex task completion has significantly improved. However, current control strategies require extensive domain expertise...

Background/Objectives: Vaccination coverage among adolescents remains below the recommended target, highlighting the need for effective educational strategies to improve vaccine knowledge. This study aimed to assess baseline knowledge of vaccines and...

Anesthesia is the gold standard for immobilization of tumor-bearing mice before radiotherapy which potentially induces stress and distorts disease progression. Irradiation of preclinical cancer models with clinical MV linear accelerator (LINAC) beams...

Background: Robot-assisted laparoscopic ureteral reimplantation via an extravesical approach (RALUR-EV) is an established minimally invasive option for vesicoureteral reflux (VUR); however, surgical success remains variable, and detrusorraphy techniq...

The objective of this paper is to rigorously define the Kadec-Klee property for modular spaces endowed with a sequential convergence structure, and to demonstrate that this property leads to normal structure in such spaces. Consequently, we establish...

Against the backdrop of China’s national initiatives to strengthen the teaching workforce, fostering teachers’ work passion is essential not only for enhancing professional well-being but also for improving educational quality. This study...

This study evaluates 10 bar water aging effects on reciprocating tribology of FDM-printed PLA and PLA with 10 and 15 wt.% glass fiber (GF). Water uptake was Fickian, and saturation mass rose from 0.0845 g (PLA) to 0.1625 g and 0.295 g (10 and 15 wt.%...

Studies on links between Oral Health-Related Quality of Life (OHRQoL) and use of dental services among UK children are lacking. This study aimed to assess the relationship between OHRQoL and dental attendance in 12- and 15-year-old children in the UK...