Announcements

“Potential for Applying Continuous Directed Evolution to Plant Enzymes: An Exploratory Study”

Jorge D. García-García et al.

Available online: https://doi.org/10.3390/life10090179

“Advances in Cereal Crop Genomics for Resilience under Climate Change”

Tinashe Zenda et al.

Available online: https://www.mdpi.com/2075-1729/11/6/502

“MicroRNAs: Potential Targets for Developing Stress-Tolerant Crops”

Saurabh Chaudhary et al.

Available online: https://doi.org/10.3390/life11040289

“Effect of Chlorination on Microbiological Quality of Effluent of a Full-Scale Wastewater Treatment Plant”

Ioanna Zerva et al.

Available online: https://doi.org/10.3390/life11010068

“Priming by High Temperature Stress Induces MicroRNA Regulated Heat Shock Modules Indicating Their Involvement in Thermopriming Response in Rice”

Akhilesh Kumar Kushawaha et al.

Available online: https://www.mdpi.com/2075-1729/11/4/291

“Biosensors: A Sneak Peek into Plant Cell’s Immunity”

Valentina Levak et al.

Available online: https://doi.org/10.3390/life11030209

“Sorghum’s Whole-Plant Transcriptome and Proteome Responses to Drought Stress: A Review”

Rudo Ngara et al.

Available online: https://doi.org/10.3390/life11070704

“Horizontal Gene Transfers in Plants”

Emilie Aubin et al.

Available online: https://www.mdpi.com/2075-1729/11/8/857

“A Label-Free Proteomic and Complementary Metabolomic Analysis of Leaves of the Resurrection Plant Xerophyta schlechteri during Dehydration”

Hawwa Gabier et al.

Available online: https://doi.org/10.3390/life11111242

“Tetraedron minimum, First Reported Member of Hydrodictyaceae to Accumulate Secondary Carotenoids”

Philipp Doppler et al.

“Bottom-Up Approaches to Synthetic Cooperation in Microbial Communities”
Daniel Rodríguez Amor and Martina Dal Bello
Available online: https://doi.org/10.3390/life9010022

“Synthetic Approaches for Nucleic Acid Delivery: Choosing the Right Carriers”
Rong Ni et al.
Available online: https://doi.org/10.3390/life9030059

“Synthetic Biology for Terraformation Lessons from Mars, Earth, and the Microbiome”
Nuria Conde-Pueyo et al.
Available online: https://doi.org/10.3390/life10020014

“TCA Cycle Replenishing Pathways in Photosynthetic Purple Non-Sulfur Bacteria Growing with Acetate”
Ekaterina Petushkova et al.
Available online: https://doi.org/10.3390/life11070711

“Analysis of the Innovation Trend in Cell-Free Synthetic Biology”
Conary Meyer et al.
Available online: https://doi.org/10.3390/life11060551

“Exploring the Impact of Terminators on Transgene Expression in Chlamydomonas reinhardtii with a Synthetic Biology Approach”
Katrin Geisler et al.
Available online: https://doi.org/10.3390/life11090964

“Build-a-Cell: Engineering a Synthetic Cell Community”
Caroline Frischmon et al.
Available online: https://doi.org/10.3390/life11111176

“The Future of Origin of Life Research: Bridging Decades-Old Divisions”
Martina Preiner et al.
Available online: https://doi.org/10.3390/life10030020

“Aptamers, Riboswitches, and Ribozymes in S. cerevisiae Synthetic Biology”
Huanhuan Ge and Mario Andrea Marchisio
Available online: https://doi.org/10.3390/life11030248

“Synthetic Biology Approaches to Engineer Saccharomyces cerevisiae towards the Industrial Production of Valuable Polyphenolic Compounds”
João Rainha et al.
Available online: https://doi.org/10.3390/life10050056

“Novel Methylation Patterns Predict Outcomes in Uveal Melanoma”
Sarah Tadhg Ferrier et al.
Life 2020, 10, 248; 10.3390/life9030067
Available online: https://doi.org/10.3390/life10100248

“Treatment of Advanced Melanoma: Past, Present, and Future”
Taku Fujimura et al.
Life 2020, 10, 208; 10.3390/life10090208
Available online: https://doi.org/10.3390/life10090208

“SOX11, SOX10, and MITF Gene Interaction: A Possible Diagnostic Tool in Malignant Melanoma”
Marius-Alexandru Beleaua et al.
Life 2021, 11, 281; 10.3390/life11040281
Available online: https://doi.org/10.3390/life11040281

“Long-Term Maintained Response to Selective Internal Radiation Therapy in an Oligometastatic Uveal Melanoma Patient Treated with Concomitant Anti-PD-1 Therapy”
Ilaria Proietti et al.
Life 2021, 11, 692; 10.3390/life11070692
Available online: https://doi.org/10.3390/life11070692

“Potential Reasons for Unresponsiveness to Anti-PD1 Immunotherapy in Young Patients with Advanced Melanoma”
Devayani Machiraju et al.
Life 2021, 11, 1318; 10.3390/life11121318
Available online: https://doi.org/10.3390/life11121318

“Cancer Stem Cells in Head and Neck Metastatic Malignant Melanoma Express Components of the Renin–Angiotensin System”
Sam Siljee et al.
Life 2020, 10, 268; 10.3390/life10110268
Available online: https://doi.org/10.3390/life10110268

“Ephrin Receptors (Eph): EphA1, EphA5, and EphA7 Expression in Uveal Melanoma—Associations with Clinical Parameters and Patient Survival”
Malgorzata Gajdzis et al.
Life 2020, 10, 225; 10.3390/life10100225
Available online: https://doi.org/10.3390/life10100225

“Chromosomal Instability May Not Be a Predictor for Immune Checkpoint Inhibitors from a Comprehensive Bioinformatics Analysis”
Chiao-En Wu et al.
Life 2020, 10, 276; 10.3390/life10110276
Available online: https://doi.org/10.3390/life10110276

“Hippo Signaling Pathway as a New Potential Target in Non-Melanoma Skin Cancers: A Narrative Review”
Igor Aleksander Bednarski et al.
Life 2021, 11, 680; 10.3390/life11070680
Available online: https://doi.org/10.3390/life11070680

“Structure, Activity, and Function of the SETDB1 Protein Methyltransferase”
Mariam Markouli et al.
Life 2021, 11, 817; 10.3390/life11080817
Available online: https://doi.org/10.3390/life11080817

Conference name: 8^th European Stroke Organisation Conference (ESOC)

Conference website: https://2022.eso-conference.org/

Date: 4–6 May 2022

Venue: Lyon, France

ESOC 2022, taking place 4–6 May 2022, is Europe’s leading forum, and indeed a leading forum worldwide for advances in research and clinical care of patients with cerebrovascular diseases. ESOC 2022 will live up to its expectation, and present to you a packed, high-quality scientific program, including major clinical trials, state-of-the-art seminars, educational workshops, scientific communications of the latest research, and debates about current controversies and dilemmas.

1. "Interaction of Oxidative Stress and Misfolded Proteins in the Mechanism of Neurodegeneration"
Abramov, A.Y.; Potapova, E.V.; Dremin, V.V. and Dunaev, A.V.
https://doi.org/10.3390/life10070101

2. "Amyloidogenic Intrinsically Disordered Proteins: New Insights into Their Self-Assembly and Their Interaction with Membranes"
Scollo, F. and La Rosa, C.
https://doi.org/10.3390/life10080144

3. "Optimization of Molecular Dynamics Simulations of c-MYC^1-88—An Intrinsically Disordered System"
Sullivan, S.S. and Weinzierl, R.O.J.
https://doi.org/10.3390/life10070109

4. "The Conformational Plasticity Vista of PDZ Domains"
Murciano-Calles, J.
https://doi.org/10.3390/life10080123

5. "Functional Mammalian Amyloids and Amyloid-Like Proteins"
Rubel, M.S.; Fedotov, S.A.; Grizel, A.V.; Sopova, J.V.; Malikova, O.A.; Chernoff, Y.O. and Rubel, A.A.
https://doi.org/10.3390/life10090156

1. “Universal Molecular Triggers of Stress Responses in Cyanobacterium Synechocystis”

Kirill S. Mironovet al.

Life 2019, 9, 67; 10.3390/life9030067

Available online: https://doi.org/10.3390/life9030067

2. “On the Role and Production of Polyhydroxybutyrate (PHB) in the Cyanobacterium Synechocystis sp. PCC 6803”

Moritz Koch et al.

Life 2020, 10, 47; 10.3390/life10040047

Available online: https://doi.org/10.3390/life10040047

3. “Diurnal Regulation of In Vivo Localization and CO2-Fixing Activity of Carboxysomes in Synechococcus elongatus PCC 7942”

Yaqi Sun et al.

Life 2020, 10, 169; 10.3390/life10090169

Available online: https://doi.org/10.3390/life10090169

4. “Over Expression of the Cyanobacterial Pgr5-Homologue Leads to Pseudoreversion in a Gene Coding for a Putative Esterase in Synechocystis 6803”

Ketty Margulis et al.

Life 2020, 10, 174; 10.3390/life10090174

Available online: https://doi.org/10.3390/life10090174

5. “The Role of the Cyanobacterial Type IV Pilus Machinery in Finding and Maintaining a Favourable Environment”

Fabian D. Conradi et al.

Life 2020, 10, 252; 10.3390/life10110252

Available online: https://doi.org/10.3390/life10110252

6. “Rapid Transcriptional Reprogramming Triggered by Alteration of the Carbon/Nitrogen Balance Has an Impact on Energy Metabolism in Nostoc sp. PCC 7120”

Marius Surleac et al.

Life 2020, 10, 297; 10.3390/life10110297

Available online: https://doi.org/10.3390/life10110297

7. “Genome Editing by CRISPR-Cas: A Game Change in the Genetic Manipulation of Chlamydomonas”

Manel Ghribi et al.

Life 2020, 10, 295; 10.3390/life10110295

Available online: https://doi.org/10.3390/life10110295

8. “Arsenolipids in Cultured Picocystis Strain ML and Their Occurrence in Biota and Sediment from Mono Lake, California”

Ronald A. Glabonjat et al.

Life 2020,10, 93; 10.3390/life10060093

Available online: https://doi.org/10.3390/life10060093

9. “Diatom-Derived Polyunsaturated Aldehydes Are Unlikely to Influence the Microbiota Composition of Laboratory-Cultured Diatoms”

Chloe L. Eastabrook et al.

Life 2020, 10, 29; 10.3390/life10030029

Available online: https://doi.org/10.3390/life10030029

10. “Rapid and Efficient Colony-PCR for High Throughput Screening of Genetically Transformed Chlamydomonas reinhardtii”

Serge Basile Nouemssi et al.

Life 2020, 10, 186; 10.3390/life10090186

Available online: https://doi.org/10.3390/life10090186

It is our great honor to congratulate the Editorial Board Members and Editors in MDPI's journals who have been distinguished as 2021 Highly Cited Researchers by Clarivate, according to Web of Science data. We herewith express our gratitude for the immense impact the named researchers continue to make on scientific progress and on our journals' development.

Clarivate's annual list of Highly Cited Researchers^TM identifies the most highly cited scientists for the past decade. Their impactful papers are among the top 1 per cent in the citation distribution of one or more of 22 fields analyzed in the "Essential Science Indicators", distinguishing them as hugely influential among their peers.

The full list of 2021 Highly Cited Researchers  can be accessed at the following webpage in the Web of Science^TM https://recognition.webofscience.com/awards/highly-cited/2021/.

--- Highly Cited Researchers (HCR) is a Clarivate product.