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Healthcare

Healthcare is an international, scientific, peer-reviewed, open access journal on health care systems, industry, technology, policy, and regulation, and is published semimonthly online by MDPI.
The European Medical Association (EMA), Ocular Wellness & Nutrition Society (OWNS) and Italian Society of Nephrology Nurses (SIAN) are affiliated with Healthcare and their members receive discounts on the article processing charges.
Indexed in PubMed | Quartile Ranking JCR - Q2 (Health Policy and Services | Health Care Sciences and Services)

All Articles (14,741)

  • Systematic Review
  • Open Access

Background: As ageing populations grow, the prevalence of dementia and pre-dementia conditions is rising. Emerging approaches to neurorehabilitation emphasize not only performance-based outcomes but also holistic, experiential, and person-centred aspects of care. The extended mind thesis further highlights the potential role of external tools in supporting impaired cognitive functions. Within this ecological and experiential perspective, Social Assistive Robotics (SAR) may offer a multidimensional approach to address cognitive, emotional, and social needs in neurocognitive disorders. Objective: To synthesize current evidence on the effects of robotic interventions within an enactive framework integrating mind, body, environment, and technology. Methods: A systematic search was conducted in PubMed, Ovid Medline, Scopus, ScienceDirect, Springer, Wiley, IEEE Xplore, ACM Digital Library, and the Cochrane Library. Due to heterogeneity among included studies, an umbrella review was performed using vote-counting by direction of effect as a non-quantitative synthesis method. Methodological rigour followed JBI and Cochrane guidelines. Results: Sixteen reviews were included. The strongest and most consistent benefits emerged for affective outcomes, particularly emotional response and social interaction p = 0.007 (two-sided). Conversely, outcomes related to cognition, anxiety, agitation, depression, and quality of life showed mixed or non-significant effects, while neuropsychiatric symptoms demonstrated no benefit. Conclusions: Discrepancies across reviews seem driven by methodological limitations in primary studies, limiting interpretability. The strength of this umbrella review lies in identifying systematic gaps that can guide future research. With stronger evidence, integrating SAR into experiential neurorehabilitation may offer a promising avenue for holistic, ecologically grounded care that extends beyond traditional task-based performance. Trial Registration: PROSPERO CRD420251165419.

26 December 2025

PRISMA flow diagram.

Background/Objectives: Luteinizing hormone-releasing hormone agonists (LHRHa) are widely used to induce ovarian suppression in premenopausal women with hormone receptor-positive breast cancer. Although effective, abrupt medical menopause may negatively affect sexual health and intimate partner interactions. Sexual coercion—ranging from manipulation to explicit pressure—remains an underrecognized psychosocial burden in oncology. This multicenter study aimed to evaluate the association between LHRHa therapy and sexual coercion, including relational dynamics measured through the Sexual Coercion in Intimate Relationships Scale (SCIRS). Methods: This cross-sectional study included 81 premenopausal breast cancer patients receiving endocrine therapy at three tertiary centers in Türkiye. Participants were categorized into tamoxifen monotherapy users (n = 39) and LHRHa users (n = 42). Sexual coercion was assessed using the validated Turkish SCIRS, which includes Resource Manipulation/Violence, Defection Threat, and Commitment Manipulation domains. Mann–Whitney U, Kruskal–Wallis, and ANCOVA analyses were performed, adjusting for age, treatment duration, surgery type, chemotherapy, radiotherapy, and education level. The study was ethically approved (2023-KAEK-148) and prospectively registered (NCT06840847). Results: LHRHa users demonstrated significantly higher SCIRS scores across all domains compared with non-users (RM/V: p = 0.039; DT: p = 0.001; CM: p < 0.001; Total: p = 0.004). ANCOVA confirmed LHRHa therapy as an independent predictor after adjusting for covariates (p = 0.001–0.006). The largest effect was observed in the Commitment Manipulation domain (partial η2 = 0.177). Younger patients (≤ 36 years) reported significantly greater coercion exposure across all domains (p = 0.018–0.042). Conclusions: LHRHa therapy is associated with increased sexual coercion and strained relational dynamics in premenopausal breast cancer patients, particularly among younger women. These findings emphasize the need for routine sexual health assessment, confidential psychosocial screening, and age-sensitive supportive interventions in endocrine therapy management.

26 December 2025

Background/Objectives: Eating mindfulness and healthy lifestyle behaviors play a key role in preventing unhealthy weight gain. Understanding how these behaviors differ according to exercise habits can guide interventions targeting women’s health. This study aimed to compare healthy lifestyle behaviors and eating mindfulness between women with and without regular exercise habits. Methods: A cross-sectional, analytical, and descriptive study was conducted with 156 women: a Regular Exercise Group (REG, n = 68) and a Non-Exercise Group (NEG, n = 88). Data were collected through face-to-face interviews using the Mindful Eating Questionnaire (MEQ-30) and the Healthy Lifestyle Behavior Scale II (HLBS-II), along with dietary records and anthropometric measurements. Results: The REG scored significantly higher in eating discipline (p = 0.003) and in HLBS-II subscales of physical activity, nutrition, and stress management (p < 0.05). No significant differences were found in total MEQ scores, BMI-related nutrient intake, or other HLBS-II dimensions (p > 0.05). BMI values and smoking rates were lower in the REG (p < 0.05). Univariate logistic regression showed that BMI, eating discipline, physical activity, nutrition, stress management, and total HPLP-II scores were significantly associated with regular exercise (p < 0.05). In the multivariate model, BMI (OR = 1.114, 95% CI: 1.021–1.216) remained independently associated with regular exercise status. Conclusions: Although eating discipline was higher in the REG, overall mindful eating levels did not differ between groups. BMI were the strongest independent variables associated with regular exercise status, suggesting that while exercise supports positive lifestyle patterns, enhancing mindful eating may require additional targeted interventions.

26 December 2025

In contemporary health discourse, the terms “mental health,” “psychological health,” and “social wellbeing” are prominent, collectively representing the emotional, cognitive, and social facets of overall wellness [...]

26 December 2025

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Editors: Victor R. Prybutok, Gayle Linda Prybutok
A Needle in a Haystack
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Looking for Gaps in Treatment and Education in Emergency Medicine
Editors: Klaudiusz Nadolny, Filip Jaśkiewicz

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Healthcare - ISSN 2227-9032