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Life publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Current Trends in Obstructive Sleep Apnea

edited by Kimberly A. Hardin

submission deadline 15 Aug 2025 | 3 articles | Viewed by 2276 | Submission Open

Keywords: obstructive sleep apnea ; diagnosis and biomarkers ; personalized treatment strategies ; clinical phenotypes ; innovative therapies

(This special issue belongs to the Section Medical Research)

Natural Bioactives: Exploring Their Therapeutic Potential—2nd Edition

edited by

Dagmara Wróbel-Biedrawa

submission deadline 20 Aug 2025 | 4 articles | Viewed by 4385 | Submission Open

Keywords: bioactive compounds; medicinal plants; bioactive metabolites with antioxidant properties; anti-inflammatory properties; antitumor properties; cytotoxic properties; antipsychotic properties; anxiolytic properties; neuroprotective properties; hypotensive properties; vasorelaxant properties; antimicrobial properties (antiviral; antibacterial; antifungal; and antiparasitic properties)

(This special issue belongs to the Section Pharmaceutical Science)

Environmental Stress and Adaptation: Molecular Mechanisms and Ecosystems Biodiversity

edited by

Mizanur Rahman

and

Takashi Asaeda

submission deadline 21 Aug 2025 | Viewed by 308 | Submission Open

Keywords: abiotic oxidative stress; aquatic biodiversity monitoring; reactive oxygen species; riparian and mangrove vegetation management; environmental DNA (eDNA) metabarcoding

(This special issue belongs to the Section Diversity and Ecology)

New Insights Into Artificial Intelligence in Medical Imaging

edited by

Luigi La Via

Antonino Maniaci

Caterina Gagliano

and Salvatore Lavalle

submission deadline 22 Aug 2025 | 3 articles | Viewed by 8102 | Submission Open

Keywords: artificial intelligence; machine learning; deep learning; image analysis; precision medicine; image-guided interventions; decision support systems

(This special issue belongs to the Section Radiobiology and Nuclear Medicine)

Advances in Endovascular Therapies and Acute Stroke Management

edited by

Anna Podlasek

submission deadline 25 Aug 2025 | 2 articles | Viewed by 1309 | Submission Open

Keywords: mechanical thrombectomy; endovascular reperfusion; stroke intervention technologies; acute ischemic stroke treatment; stroke imaging biomarkers

(This special issue belongs to the Section Medical Research)

Applications of Molecular Dynamics to Biological Systems

edited by

Ron Elber

submission deadline 26 Aug 2025 | 3 articles | Viewed by 2373 | Submission Open

Keywords: computer simulation; biophysical modeling; molecular dynamics

(This special issue belongs to the Section Biochemistry, Biophysics and Computational Biology)

Hand Soft Tissue Disorders: Mechanisms and Therapeutic Advances

edited by Ishith Seth

submission deadline 26 Aug 2025 | 1 articles | Viewed by 1084 | Submission Open

Keywords: dupuytren’ s disease; hand soft tissue disorders; genomics; biomarkers; artificial intelligence

(This special issue belongs to the Section Medical Research)

Pharmacology, Diagnosis and Treatments of Psychiatric Diseases

edited by Giuseppe Marano and

Marianna Mazza

submission deadline 26 Aug 2025 | Viewed by 344 | Submission Open

Keywords: mental health disorders; clinical psychology; psychopharmacology; treatment efficacy; neuroimaging techniques; personalized medicine; diagnosis

(This special issue belongs to the Section Medical Research)

Emerging Applications of Nanobiotechnology in Medicine and Health

edited by Roshanak Khandanlou

submission deadline 28 Aug 2025 | Viewed by 183 | Submission Open

Keywords: nanobiotechnology; targeted drug-delivery; tissue engineering; cancer treatment; regenerative medicine; medical applications

(This special issue belongs to the Section Medical Research)

Applications of Dermatoscopy in Skin Diseases

edited by

Paweł Pietkiewicz

Enzo Errichetti

and

Cristian Navarrete

submission deadline 29 Aug 2025 | 5 articles | Viewed by 34398 | Submission Open

Keywords: melanoma; skin cancer; inflammoscopy; trichoscopy; ultraviolet reflectance dermatoscopy; skin of colour; basal cell carcinoma; squamous cell carcinoma; nevus; digital dermoscopy

(This special issue belongs to the Section Medical Research)

Cystic Fibrosis: A Disease with a New Face

edited by

Janice Wang

and Patricia A. Walker

submission deadline 29 Aug 2025 | 11 articles | Viewed by 33627 | Submission Open

Keywords: cystic fibrosis; CFTR modulator; CF newborn screening; CF nutrition; lung transplant in CF; CF family planning

(This special issue belongs to the Section Medical Research)

Elements Cycling and Plants’ Physiological Characteristics: A Soil–Plant–Atmosphere Continuum Perspective

edited by

Ling Zhang

and

Zhi Li

submission deadline 29 Aug 2025 | 7 articles | Viewed by 14557 | Submission Open

Keywords: element cycling; microbial communities; plant nutrition; plant physiology; plant biochemistry; atmospheric composition; climate change; soil– plant– atmosphere interaction; plant– soil feedback

(This special issue belongs to the Section Plant Science)

Nutritional Supplementation, Body Composition and Performance in Athletes

edited by

Bojan Knap

submission deadline 29 Aug 2025 | 2 articles | Viewed by 12695 | Submission Open

Keywords: optimal macro and micronutrients in exercise; plant-based food in sports nutrition; beetroot as ergogenic aid; body mass composition and nutrition practice; phase angle as VO2 max predictor; RED syndrome low and high energetic availability in sports praxis

(This special issue belongs to the Section Physiology and Pathology)

Current Progress in Medical Image Segmentation

edited by

Krishna Chaitanya

submission deadline 29 Aug 2025 | 5 articles | Viewed by 7429 | Submission Open

Keywords: medical image segmentation; deep learning; generative models; algorithm; clinical integration; biological variability; transformer architectures; interactive segmentation; interdisciplinary collaboration

(This special issue belongs to the Section Radiobiology and Nuclear Medicine)

Gynecological Endocrinology: From Physiological Mechanisms to Clinical Practice

edited by Ralitsa Robeva

submission deadline 29 Aug 2025 | 3 articles | Viewed by 6226 | Submission Open

Keywords: PCOS; hypothalamic amenorrhea; congenital adrenal hyperplasia; hypogonadotropic hypogonadism; premature ovarian insufficiency (POI)

(This special issue belongs to the Section Physiology and Pathology)

The Emerging Role of Microbiota in Health and Diseases

edited by Edyta Juszczuk-Kubiak and Katarzyna Góralska

submission deadline 29 Aug 2025 | 4 articles | Viewed by 6220 | Submission Open

Keywords: microbiota; eubiosis; dysbiosis; microbiota– host interaction; microbiota– gut– brain axis; microbiome; bacteria– fungi interactions; microbiota modification; holobiont; cross-feeding; microbiota related diseases; microbiota functions

(This special issue belongs to the Section Microbiology)

Clinical and Laboratory Advancements and Challenges in Medically Assisted Reproduction

edited by

Alessandra Alteri

and Valeria Stella Vanni

submission deadline 29 Aug 2025 | 2 articles | Viewed by 6071 | Submission Open

Keywords: medically assisted reproduction; assisted reproduction technologies; clinical embryology; genetic testing; ovarian stimulation; male factor; endometriosis; endometrial receptivity; implantation

(This special issue belongs to the Section Reproductive and Developmental Biology)

Diagnosis and Management of Microbial Infections

edited by

Iulia-Cristina Bagiu

submission deadline 29 Aug 2025 | 3 articles | Viewed by 4618 | Submission Open

Keywords: microbiology; infection; germs; antimicrobial agents; antimicrobial therapy

(This special issue belongs to the Section Microbiology)

Personalized Medicine in Ophthalmic Diseases: Updated Challenges and Opportunities

edited by

Camelia Margareta Bogdanici

submission deadline 29 Aug 2025 | 4 articles | Viewed by 4335 | Submission Open

Keywords: vision-related quality of life; personalized medicine; artificial intelligence; ophthalmology and nutrition; optical coherence tomography; ocular surface diseases; retinal vascular diseases

(This special issue belongs to the Section Medical Research)

Bone Cancer: From Molecular Mechanism to Treatment

edited by

Chih-Yang Lin

and Syuan-Ling Lin

submission deadline 29 Aug 2025 | 3 articles | Viewed by 3846 | Submission Open

Keywords: bone cancer; metastasis; angiogenesis; targeted drugs; biomarkers

(This special issue belongs to the Section Medical Research)

Precision Medicine in Cardiovascular Diseases

edited by Brian Xiangzhi Wang

submission deadline 29 Aug 2025 | 1 articles | Viewed by 2348 | Submission Open

Keywords: genomic; cardiovascular disease; congenital; multi-omics studies; precision medicine; personalized medicine; biomarker

(This special issue belongs to the Section Genetics and Genomics)

Current Research on Dermatology: Pathology, Clinical Manifestation, Investigation and Therapy—Third Edition

edited by

Alin Laurentiu Tatu

submission deadline 29 Aug 2025 | 2 articles | Viewed by 1827 | Submission Open

Keywords: Demodex; endosymbionts; cutaneous microbiome; integrative medicine; optical coherence tomography; dermoscopy; confocal microscopy; cutaneous comorbidities keyword; inflammatory diseases; hair; skin cancer; comorbidities; skin surgery

(This special issue belongs to the Section Physiology and Pathology)

Kidney Transplantation: What’s Hot and What’s New—2nd Edition

edited by

Giuseppe Ietto

and Caterina Di Bella

submission deadline 29 Aug 2025 | 1 articles | Viewed by 1349 | Submission Open

Keywords: kidney transplantation; immunosuppression; graft quality; machine perfusion (MP); living-donor kidney transplantation

(This special issue belongs to the Section Medical Research)

Channel Proteins and Transporters in Human Health and Disease

edited by

Giorgia Scarpellino

Giorgia Chinigò

and

Roberta De Zio

submission deadline 29 Aug 2025 | Viewed by 976 | Submission Open

Keywords: channel proteins; transporters; ion channel

(This special issue belongs to the Section Proteins and Proteomics)

Image Analysis and Postprocessing in Medical Imaging

edited by

Federico Bruno

submission deadline 29 Aug 2025 | Viewed by 248 | Submission Open

Keywords: quantitative imaging biomarkers; image segmentation; artificial intelligence in radiology; image postprocessing

(This special issue belongs to the Section Medical Research)

Microbiota Metabolism and Gut Health in Swine

edited by

Yu Pi

submission deadline 29 Aug 2025 | Viewed by 195 | Submission Open

Keywords: gut microbiota; swine health; microbial metabolites; nutrient absorption; immune response; metagenomics; antibiotic alternatives; swine production

(This special issue belongs to the Section Microbiology)

Disparities in Cancer Treatment

edited by Adam Barsouk

submission deadline 29 Aug 2025 | Viewed by 143 | Submission Open

Keywords: disparities; mortality; survival; race; sex; age; developing nations; public health; prevention

(This special issue belongs to the Section Epidemiology)

Hansen's Disease—Epidemiology, Diagnosis, Treatment and Complications

edited by Karen Olshtain-Pops

submission deadline 30 Aug 2025 | 1 articles | Viewed by 2948 | Submission Open

Keywords: hansen's disease; leprosy; Mycobacterium leprae

(This special issue belongs to the Section Epidemiology)

Latest Updates on Clinical Microbiology and Antimicrobial Resistant Infection

edited by Jun Sung Hong

submission deadline 30 Aug 2025 | 2 articles | Viewed by 1436 | Submission Open

Keywords: enterobacteriaceae; antimicrobial resistance; infection; health

(This special issue belongs to the Section Microbiology)

Microorganisms Engineering and Gene-Editing Methods

edited by

Jichao Wang

Guang Zhao

and Xia Zhao

submission deadline 30 Aug 2025 | 1 articles | Viewed by 892 | Submission Open

Keywords: microorganisms engineering; metabolic engineering; strain optimization; gene editing; CRISPR; recombination

(This special issue belongs to the Section Genetics and Genomics)

Animal Nutritional Physiology: Effects of Feed Additives on Livestock Products

edited by

Anna Arczewska-Włosek

and Katarzyna Poltowicz

submission deadline 30 Aug 2025 | Viewed by 803 | Submission Open

Keywords: feed additives; animal health; animal performance; animal-derived products; animal nutritional physiology

(This special issue belongs to the Section Physiology and Pathology)

Feature Papers in Medical Research: 3rd Edition

edited by

Christian Lehmann

submission deadline 31 Aug 2025 | 14 articles | Viewed by 20352 | Submission Open

Keywords: dermatological research; cancer research; cardiovascular research; general medicine; gastroenterological research; hematological research; immunological research; infectious diseases research; metabolism and endocrinology; nervous system research; nursing; pediatrics; pulmonary research; psychiatric research; rehabilitation; renal and urinary research; reproductive research and women's health; rheumatological research; skeletal and muscular research; vision research

(This special issue belongs to the Section Medical Research)

Recent Advances in Crop Genetics and Breeding

edited by

Tianxiao Chen

Xiangjin Wei

Baohua Feng

and Long Chen

submission deadline 31 Aug 2025 | 5 articles | Viewed by 5047 | Submission Open

Keywords: crop; high-throughput genotyping; genetic resources; favorable haplotype; marker-assisted selection; genome editing; CRISPR-Cas9; genomic selection

(This special issue belongs to the Section Plant Science)

Clinical Manifestations and Treatment of Autoimmune Diseases: 2nd Edition

edited by

Stelvio Tonello

and

Daniele Sola

submission deadline 31 Aug 2025 | 3 articles | Viewed by 2522 | Submission Open

Keywords: autoimmunity; immunobiology; vaccine; leucocytes; immune system

(This special issue belongs to the Section Medical Research)

Migraine and Headache: From Pathophysiological Aspects

edited by

Jacob Genizi

submission deadline 31 Aug 2025 | 2 articles | Viewed by 1827 | Submission Open

Keywords: migraine; headache; pathophysiology; treatment; medication

(This special issue belongs to the Section Physiology and Pathology)

Encephalitis: From Molecular Pathophysiology to Therapy

edited by Anna Tröscher and Judith Wagner

submission deadline 31 Aug 2025 | 1 articles | Viewed by 1310 | Submission Open

Keywords: infectious encephalitis; autoimmune encephalitis; neuroinflammation; pathophysiology; diagnostics; therapy

(This special issue belongs to the Section Physiology and Pathology)

New Insights into Pediatric Rheumatic and Autoimmune Diseases

edited by

Lampros Fotis

submission deadline 31 Aug 2025 | 1 articles | Viewed by 852 | Submission Open

Keywords: arthritis; juvenile; autoimmune diseases; biomarkers; diagnostic imaging; juvenile dermatomyositis; lupus erythematosus; systemic; pediatric rheumatology; vasculitis

(This special issue belongs to the Section Medical Research)

Innovative Drug Development: Balancing Efficacy and Toxicity in Novel Pharmaceuticals

edited by

Iasmina Marcovici

submission deadline 31 Aug 2025 | 1 articles | Viewed by 768 | Submission Open

Keywords: drug development; pharmaceuticals; bioactive compounds; new drug candidates; drug delivery systems; pharmaceutical formulations; efficacy and toxicity screening

(This special issue belongs to the Section Pharmaceutical Science)

Recent Advances in Plant Genomics and Genetics

edited by

Tianxiao Chen

Baohua Feng

, Long Chen and

Xiangjin Wei

submission deadline 31 Aug 2025 | Viewed by 735 | Submission Open

Keywords: high-throughput genotyping; plant genetics; plant genomics; genetic markers; genetic improvements; genome editong; CRISPR/Cas9; genomic selection

(This special issue belongs to the Section Genetics and Genomics)

Integrating Health Informatics and Artificial Intelligence for Advanced Medicine

edited by

Joaquim Carreras

submission deadline 31 Aug 2025 | Viewed by 251 | Submission Open

Keywords: artificial intelligence; machine learning; artificial neural networks; prognosis; treatment; medicine; health care; pathology

(This special issue belongs to the Section Medical Research)

Recent Advances in Bone Biology

edited by Barbara Peruzzi,

Martina Leopizzi

and Giulia Battafarano

submission deadline 31 Aug 2025 | Viewed by 228 | Submission Open

Keywords: bone tissue engineering; bone-targeted therapies; genetic bone diseases; bone mechanotransduction; bone cell pathophysiology; bone metabolism

(This special issue belongs to the Section Physiology and Pathology)

Body Fluid-Based Biomarkers for Cognitive Impairment

edited by Wei Li

submission deadline 31 Aug 2025 | Viewed by 195 | Submission Open

Keywords: Alzheimer’ s disease and related dementia (ADRD); body fluid-based biomarkers; cognitive impairments; early diagnosis; treatment; prognosis

(This special issue belongs to the Section Medical Research)

Cutting-Edge Techniques and Innovations in the Management of Aortic Aneurysm

edited by Dimitrios Iliopoulos

submission deadline 31 Aug 2025 | Viewed by 179 | Submission Open

Keywords: aneurysm; aorta; aortic root; biomechanics; aortic dissection; thoracoabdominal aneurysm; valve-sparing aortic root replacement; perfusion

(This special issue belongs to the Section Medical Research)

New Insights into Cellular Inflammation and Regeneration

edited by

Jea-Hyun Baek

submission deadline 31 Aug 2025 | Viewed by 179 | Submission Open

Keywords: cellular inflammation; tissue regeneration; immune modulation; regenerative medicine; inflammatory pathways; immune cells and tissue repair; chronic inflammation; biomarkers of regeneration; immune-tissue crosstalk; wound healing; fibrosis and regeneration; inflammation resolution; tissue remodeling; regenerative microenvironment; inflammation-driven pathogenesis; translational immunology

(This special issue belongs to the Section Physiology and Pathology)

Migraine and Headache: From Clinical and Therapeutic Aspects

edited by

Jacob Genizi

submission deadline 31 Aug 2025 | Viewed by 166 | Submission Open

Keywords: migraine; headache; treatment; medication

(This special issue belongs to the Section Medical Research)

Gene Regulation and Expression in Tumors

edited by

Beniamin Grabarek

and Dawid Sobański

submission deadline 31 Aug 2025 | Viewed by 151 | Submission Open

Keywords: gene regulation; tumor biology; transcriptional dysregulation and epigenetics; cancer biomarkers; therapeutic targets; multi-omics approaches

(This special issue belongs to the Section Physiology and Pathology)

The Drug Development for Neurodegenerative Diseases

edited by David R. Elmaleh

submission deadline 31 Aug 2025 | Viewed by 130 | Submission Open

Keywords: neurodegenerative disease; drug treatment approaches; quality of life improvement

(This special issue belongs to the Section Pharmaceutical Science)

Emerging Trends in Tumor Pathology and Precision Oncology

edited by

Valerio Gaetano Vellone

and Gabriele Gaggero

submission deadline 15 Sep 2025 | 2 articles | Viewed by 4933 | Submission Open

Keywords: gynecologic pathology; pediatric pathology; neuropathology; molecular diagnostics; precision oncology

(This special issue belongs to the Section Physiology and Pathology)

New Insights Into Leishmaniasis and Chagas Disease: Focus on Diagnosis and Genetic Characterization of Parasites: 2nd Edition

edited by

Alba Abras

and Cristina Ballart

submission deadline 15 Sep 2025 | 1 articles | Viewed by 2219 | Submission Open

Keywords: leishmania; leishmaniasis; chagas disease; American trypanosomiasis; Trypanosoma cruzi; diagnostics; genetic diversity; characterization; neglected tropical disease

(This special issue belongs to the Section Epidemiology)

Postbiotics—Bioactive Microbial Compounds as Health-Promoting Agents

edited by

Katarzyna Oszajca

and

Janusz Szemraj

submission deadline 15 Sep 2025 | 3 articles | Viewed by 1839 | Submission Open

Keywords: gut microbiota; postbiotics; prebiotics; microbiota-derived metabolites; postbiotic supplementation; postbiotics and health benefits; dysbiosis

(This special issue belongs to the Section Microbiology)

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