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Most Cited & Viewed - Life

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Citations	Article
63	Article: Coupled Phases and Combinatorial Selection in Fluctuating Hydrothermal Pools: A Scenario to Guide Experimental Approaches to the Origin of Cellular Life by Bruce Damer and David Deamer
55	Review: Mitigating Harmful Cyanobacterial Blooms in a Human- and Climatically-Impacted World by Hans W. Paerl
54	Review: Role of Cyanobacterial Exopolysaccharides in Phototrophic Biofilms and in Complex Microbial Mats by Federico Rossi and Roberto De Philippis
46	Review: Regulation of CO₂ Concentrating Mechanism in Cyanobacteria by Robert L. Burnap, Martin Hagemann and Aaron Kaplan
45	Review: Halophilic Bacteria as a Source of Novel Hydrolytic Enzymes by María De Lourdes Moreno, Dolores Pérez, María Teresa García and Encarnación Mellado
43	Article: Occurrence of Far-Red Light Photoacclimation (FaRLiP) in Diverse Cyanobacteria by Fei Gan, Gaozhong Shen and Donald A. Bryant
41	Article: Evolution of Microbial “Streamer” Growths in an Acidic, Metal-Contaminated Stream Draining an Abandoned Underground Copper Mine by Catherine M. Kay, Owen F. Rowe, Laura Rocchetti, Kris Coupland, Kevin B. Hallberg and D. Barrie Johnson
37	Review: Space Radiation: The Number One Risk to Astronaut Health beyond Low Earth Orbit by Jeffery C. Chancellor, Graham B. I. Scott and Jeffrey P. Sutton
33	Review: tRNA-Derived Fragments (tRFs): Emerging New Roles for an Ancient RNA in the Regulation of Gene Expression by Simon P. Keam and Gyorgy Hutvagner
32	Review: Metals in Cyanobacteria: Analysis of the Copper, Nickel, Cobalt and Arsenic Homeostasis Mechanisms by María José Huertas, Luis López-Maury, Joaquín Giner-Lamia, Ana María Sánchez-Riego and Francisco Javier Florencio

Citations	Article
2	Review: Serpentinization: Connecting Geochemistry, Ancient Metabolism and Industrial Hydrogenation by Martina Preiner, Joana C. Xavier, Filipa L. Sousa, Verena Zimorski, Anna Neubeck, Susan Q. Lang, H. Chris Greenwell, Karl Kleinermanns, Harun Tüysüz, Tom M. McCollom, Nils G. Holm and William F. Martin
2	Article: Formamide Adsorption at the Amorphous Silica Surface: A Combined Experimental and Computational Approach by Matteo Signorile, Clara Salvini, Lorenzo Zamirri, Francesca Bonino, Gianmario Martra, Mariona Sodupe and Piero Ugliengo
1	Article: Controlled Construction of Stable Network Structure Composed of Honeycomb-Shaped Microhydrogels by Masayuki Hayakawa, Satoshi Umeyama, Ken H. Nagai, Hiroaki Onoe and Masahiro Takinoue
1	Article: Appropriate Assignment of Fossil Calibration Information Minimizes the Difference between Phylogenetic and Pedigree Mutation Rates in Humans by Renata T. Capellão, Elisa M. Costa-Paiva and Carlos G. Schrago
1	Article: Dynamical Task Switching in Cellular Computers by Angel Goñi-Moreno, Fernando de la Cruz, Alfonso Rodríguez-Patón and Martyn Amos
1	Review: Exploring the Emergence of RNA Nucleosides and Nucleotides on the Early Earth by Annabelle Biscans
1	Article: A Spectral Comparison of Jarosites Using Techniques Relevant to the Robotic Exploration of Biosignatures on Mars by Liane Loiselle, Michael A. McCraig, M. Darby Dyar, Richard Léveillé, Sean R. Shieh and Gordon Southam
1	Article: Possible Emergence of Sequence Specific RNA Aminoacylation via Peptide Intermediary to Initiate Darwinian Evolution and Code through Origin of Life by Dimiter Kunnev and Anastas Gospodinov
1	Review: Chemical Diversity of Metal Sulfide Minerals and Its Implications for the Origin of Life by Yamei Li, Norio Kitadai and Ryuhei Nakamura
1	Review: The Beginning of Systems Chemistry by Peter Strazewski

Citations	Article
5	Review: Reporting Key Features in Cold-Adapted Bacteria by Paula M. Tribelli and Nancy I. López
4	Review: Green Rust: The Simple Organizing ‘Seed’ of All Life? by Michael J. Russell
3	Review: Insights into Abiotically-Generated Amino Acid Enantiomeric Excesses Found in Meteorites by Aaron S. Burton and Eve L. Berger
3	Perspective: Potential Role of Inorganic Confined Environments in Prebiotic Phosphorylation by Avinash Vicholous Dass, Maguy Jaber, André Brack, Frédéric Foucher, Terence P. Kee, Thomas Georgelin and Frances Westall
2	Review: Serpentinization: Connecting Geochemistry, Ancient Metabolism and Industrial Hydrogenation by Martina Preiner, Joana C. Xavier, Filipa L. Sousa, Verena Zimorski, Anna Neubeck, Susan Q. Lang, H. Chris Greenwell, Karl Kleinermanns, Harun Tüysüz, Tom M. McCollom, Nils G. Holm and William F. Martin
2	Article: Formamide Adsorption at the Amorphous Silica Surface: A Combined Experimental and Computational Approach by Matteo Signorile, Clara Salvini, Lorenzo Zamirri, Francesca Bonino, Gianmario Martra, Mariona Sodupe and Piero Ugliengo
2	Article: Cystobasidium alpinum sp. nov. and Rhodosporidiobolus oreadorum sp. nov. from European Cold Environments and Arctic Region by Benedetta Turchetti, Laura Selbmann, Nina Gunde-Cimerman, Pietro Buzzini, José Paulo Sampaio and Polona Zalar
2	Article: Population Dynamics of Autocatalytic Sets in a Compartmentalized Spatial World by Wim Hordijk, Jonathan Naylor, Natalio Krasnogor and Harold Fellermann
2	Article: Integrity of the DNA and Cellular Ultrastructure of Cryptoendolithic Fungi in Space or Mars Conditions: A 1.5-Year Study at the International Space Station by Silvano Onofri, Laura Selbmann, Claudia Pacelli, Jean Pierre De Vera, Gerda Horneck, John E. Hallsworth and Laura Zucconi
2	Review: Fungal Diversity in Lichens: From Extremotolerance to Interactions with Algae by Lucia Muggia and Martin Grube

Citations	Article
10	Review: Ecology and Evolution in the RNA World Dynamics and Stability of Prebiotic Replicator Systems by András Szilágyi, István Zachar, István Scheuring, Ádám Kun, Balázs Könnyű and Tamás Czárán
9	Review: Small and Random Peptides: An Unexplored Reservoir of Potentially Functional Primitive Organocatalysts. The Case of Seryl-Histidine by Rafal Wieczorek, Katarzyna Adamala, Tecla Gasperi, Fabio Polticelli and Pasquale Stano
7	Review: Nitrogenous Derivatives of Phosphorus and the Origins of Life: Plausible Prebiotic Phosphorylating Agents in Water by Megha Karki, Clémentine Gibard, Subhendu Bhowmik and Ramanarayanan Krishnamurthy
6	Review: Cryosphere and Psychrophiles: Insights into a Cold Origin of Life? by Georges Feller
6	Review: A Chemist’s Perspective on the Role of Phosphorus at the Origins of Life by Christian Fernández-García, Adam J. Coggins and Matthew W. Powner
5	Review: Reporting Key Features in Cold-Adapted Bacteria by Paula M. Tribelli and Nancy I. López
5	Concept Paper: Frozen Accident Pushing 50: Stereochemistry, Expansion, and Chance in the Evolution of the Genetic Code by Eugene V. Koonin
4	Article: Thermal Condensation of Glycine and Alanine on Metal Ferrite Surface: Primitive Peptide Bond Formation Scenario by Md. Asif Iqubal, Rachana Sharma, Sohan Jheeta and Kamaluddin
4	Article: Better than Membranes at the Origin of Life? by Helen Greenwood Hansma
4	Review: Green Rust: The Simple Organizing ‘Seed’ of All Life? by Michael J. Russell

Citations	Article
20	Review: The Role of Lipid Membranes in Life’s Origin by David Deamer
16	Article: Dry/Wet Cycling and the Thermodynamics and Kinetics of Prebiotic Polymer Synthesis by David S. Ross and David Deamer
14	Review: Multiple Layers of Stress-Induced Regulation in tRNA Biology by Hsiao-Yun Huang and Anita K. Hopper
14	Article: Coevolution Theory of the Genetic Code at Age Forty: Pathway to Translation and Synthetic Life by J. Tze-Fei Wong, Siu-Kin Ng, Wai-Kin Mat, Taobo Hu and Hong Xue
10	Review: Ecology and Evolution in the RNA World Dynamics and Stability of Prebiotic Replicator Systems by András Szilágyi, István Zachar, István Scheuring, Ádám Kun, Balázs Könnyű and Tamás Czárán
9	Article: Functional Annotations of Paralogs: A Blessing and a Curse by Rémi Zallot, Katherine J. Harrison, Bryan Kolaczkowski and Valérie De Crécy-Lagard
9	Review: Small and Random Peptides: An Unexplored Reservoir of Potentially Functional Primitive Organocatalysts. The Case of Seryl-Histidine by Rafal Wieczorek, Katarzyna Adamala, Tecla Gasperi, Fabio Polticelli and Pasquale Stano
9	Essay: A Field Trip to the Archaean in Search of Darwin’s Warm Little Pond by Bruce Damer
9	Review: From Prebiotics to Probiotics: The Evolution and Functions of tRNA Modifications by Katherine M. McKenney and Juan D. Alfonzo
7	Review: Nitrogenous Derivatives of Phosphorus and the Origins of Life: Plausible Prebiotic Phosphorylating Agents in Water by Megha Karki, Clémentine Gibard, Subhendu Bhowmik and Ramanarayanan Krishnamurthy

» More Articles

Views	Article
72968	Article: Theory of the Origin, Evolution, and Nature of Life by Erik D. Andrulis
11607	Review: Is Life Unique? by David L. Abel
10547	Editorial: Publication of Controversial Papers in Life by Shu-Kun Lin
9769	Communication: Supercritical Carbon Dioxide and Its Potential as a Life-Sustaining Solvent in a Planetary Environment by Nediljko Budisa and Dirk Schulze-Makuch
9608	Article: Approaches to the Origin of Life on Earth by Stuart A. Kauffman
8163	Article: Coupled Phases and Combinatorial Selection in Fluctuating Hydrothermal Pools: A Scenario to Guide Experimental Approaches to the Origin of Cellular Life by Bruce Damer and David Deamer
7584	Essay: The Cosmic Zoo: The (Near) Inevitability of the Evolution of Complex, Macroscopic Life by William Bains and Dirk Schulze-Makuch
7075	Review: Evolutionary Steps in the Emergence of Life Deduced from the Bottom-Up Approach and GADV Hypothesis (Top-Down Approach) by Kenji Ikehara
6285	Review: Space Radiation: The Number One Risk to Astronaut Health beyond Low Earth Orbit by Jeffery C. Chancellor, Graham B. I. Scott and Jeffrey P. Sutton
6103	Editorial: *Opening up Peer Review in Life: Towards a Transparent and Reliable Process* by Pabulo Henrique Rampelotto

Views	Article
1477	Review: Serpentinization: Connecting Geochemistry, Ancient Metabolism and Industrial Hydrogenation by Martina Preiner, Joana C. Xavier, Filipa L. Sousa, Verena Zimorski, Anna Neubeck, Susan Q. Lang, H. Chris Greenwell, Karl Kleinermanns, Harun Tüysüz, Tom M. McCollom, Nils G. Holm and William F. Martin
1245	Article: Testing New Concepts for Crop Cultivation in Space: Effects of Rooting Volume and Nitrogen Availability by Silje A. Wolff, Carolina F. Palma, Leo Marcelis, Ann-Iren Kittang Jost and Sander H. Van Delden
1196	Opinion: Real-World Synthetic Biology: Is It Founded on an Engineering Approach, and Should It Be? by Jamie A. Davies
1165	Review: Chemical Diversity of Metal Sulfide Minerals and Its Implications for the Origin of Life by Yamei Li, Norio Kitadai and Ryuhei Nakamura
1075	Article: Exposed Areas Above Sea Level on Earth >3.5 Gyr Ago: Implications for Prebiotic and Primitive Biotic Chemistry by Jeffrey L. Bada and Jun Korenaga
1018	Article: G-Protein Coupled Receptor Protein Synthesis on a Lipid Bilayer Using a Reconstituted Cell-Free Protein Synthesis System by Belay Gessesse, Takashi Nagaike, Koji Nagata, Yoshihiro Shimizu and Takuya Ueda
1003	Review: Geochemistry and the Origin of Life: From Extraterrestrial Processes, Chemical Evolution on Earth, Fossilized Life’s Records, to Natures of the Extant Life by Satoru Nakashima, Yoko Kebukawa, Norio Kitadai, Motoko Igisu and Natsuki Matsuoka
1002	Review: The Distinctive Regulation of Cyanobacterial Glutamine Synthetase by Paul Bolay, M. Isabel Muro-Pastor, Francisco J. Florencio and Stephan Klähn
825	Article: *Dissecting the Repertoire of DNA-Binding Transcription Factors of the Archaeon Pyrococcus furiosus* DSM 3638** by Antonia Denis, Mario Alberto Martínez-Núñez, Silvia Tenorio-Salgado and Ernesto Perez-Rueda
822	Review: Exploring the Emergence of RNA Nucleosides and Nucleotides on the Early Earth by Annabelle Biscans

Views	Article
3175	Article: Molecular Evolution in a Peptide-Vesicle System by Christian Mayer, Ulrich Schreiber, María J. Dávila, Oliver J. Schmitz, Amela Bronja, Martin Meyer, Julia Klein and Sven W. Meckelmann
1697	Review: Mineral Surface-Templated Self-Assembling Systems: Case Studies from Nanoscience and Surface Science towards Origins of Life Research by Richard J. Gillams and Tony Z. Jia
1511	Review: Reporting Key Features in Cold-Adapted Bacteria by Paula M. Tribelli and Nancy I. López
1481	Technical Note: phylotaR: An Automated Pipeline for Retrieving Orthologous DNA Sequences from GenBank in R by Dominic J. Bennett, Hannes Hettling, Daniele Silvestro, Alexander Zizka, Christine D. Bacon, Søren Faurby, Rutger A. Vos and Alexandre Antonelli
1477	Review: Serpentinization: Connecting Geochemistry, Ancient Metabolism and Industrial Hydrogenation by Martina Preiner, Joana C. Xavier, Filipa L. Sousa, Verena Zimorski, Anna Neubeck, Susan Q. Lang, H. Chris Greenwell, Karl Kleinermanns, Harun Tüysüz, Tom M. McCollom, Nils G. Holm and William F. Martin
1413	Article: Amphiphilic Compounds Assemble into Membranous Vesicles in Hydrothermal Hot Spring Water but Not in Seawater by Daniel Milshteyn, Bruce Damer, Jeff Havig and David Deamer
1400	Review: Fungal Diversity in Lichens: From Extremotolerance to Interactions with Algae by Lucia Muggia and Martin Grube
1383	Perspective: Potential Role of Inorganic Confined Environments in Prebiotic Phosphorylation by Avinash Vicholous Dass, Maguy Jaber, André Brack, Frédéric Foucher, Terence P. Kee, Thomas Georgelin and Frances Westall
1311	Article: Sun Exposure Shapes Functional Grouping of Fungi in Cryptoendolithic Antarctic Communities by Claudia Coleine, Laura Zucconi, Silvano Onofri, Nuttapon Pombubpa, Jason E. Stajich and Laura Selbmann
1305	Review: Green Rust: The Simple Organizing ‘Seed’ of All Life? by Michael J. Russell

Views	Article
4842	Review: The Genetic Code and RNA-Amino Acid Affinities by Michael Yarus
4277	Review: DNA Protection Protein, a Novel Mechanism of Radiation Tolerance: Lessons from Tardigrades by Takuma Hashimoto and Takekazu Kunieda
3365	Review: Nitrogenous Derivatives of Phosphorus and the Origins of Life: Plausible Prebiotic Phosphorylating Agents in Water by Megha Karki, Clémentine Gibard, Subhendu Bhowmik and Ramanarayanan Krishnamurthy
3175	Article: Molecular Evolution in a Peptide-Vesicle System by Christian Mayer, Ulrich Schreiber, María J. Dávila, Oliver J. Schmitz, Amela Bronja, Martin Meyer, Julia Klein and Sven W. Meckelmann
2495	Article: Thermal Condensation of Glycine and Alanine on Metal Ferrite Surface: Primitive Peptide Bond Formation Scenario by Md. Asif Iqubal, Rachana Sharma, Sohan Jheeta and Kamaluddin
2483	Review: Small and Random Peptides: An Unexplored Reservoir of Potentially Functional Primitive Organocatalysts. The Case of Seryl-Histidine by Rafal Wieczorek, Katarzyna Adamala, Tecla Gasperi, Fabio Polticelli and Pasquale Stano
2469	Article: Cloning and Molecular Characterization of an Alpha-Glucosidase (MalH) from the Halophilic Archaeon Haloquadratum walsbyi by Mara F. Cuebas-Irizarry, Ricardo A. Irizarry-Caro, Carol López-Morales, Keyla M. Badillo-Rivera, Carlos M. Rodríguez-Minguela and Rafael Montalvo-Rodríguez
2269	Article: Kin Selection in the RNA World by Samuel R. Levin and Stuart A. West
2256	Review: A Chemist’s Perspective on the Role of Phosphorus at the Origins of Life by Christian Fernández-García, Adam J. Coggins and Matthew W. Powner
2107	Review: Characterization of Reconstructed Ancestral Proteins Suggests a Change in Temperature of the Ancient Biosphere by Satoshi Akanuma

Views	Article
7584	Essay: The Cosmic Zoo: The (Near) Inevitability of the Evolution of Complex, Macroscopic Life by William Bains and Dirk Schulze-Makuch
6100	Essay: A Field Trip to the Archaean in Search of Darwin’s Warm Little Pond by Bruce Damer
4842	Review: The Genetic Code and RNA-Amino Acid Affinities by Michael Yarus
4647	Article: Selection of Prebiotic Molecules in Amphiphilic Environments by Christian Mayer, Ulrich Schreiber and María J. Dávila
4277	Review: DNA Protection Protein, a Novel Mechanism of Radiation Tolerance: Lessons from Tardigrades by Takuma Hashimoto and Takekazu Kunieda
3365	Review: Nitrogenous Derivatives of Phosphorus and the Origins of Life: Plausible Prebiotic Phosphorylating Agents in Water by Megha Karki, Clémentine Gibard, Subhendu Bhowmik and Ramanarayanan Krishnamurthy
3348	Review: A Self-Assembled Aggregate Composed of a Fatty Acid Membrane and the Building Blocks of Biological Polymers Provides a First Step in the Emergence of Protocells by Roy A. Black and Matthew C. Blosser
3175	Article: Molecular Evolution in a Peptide-Vesicle System by Christian Mayer, Ulrich Schreiber, María J. Dávila, Oliver J. Schmitz, Amela Bronja, Martin Meyer, Julia Klein and Sven W. Meckelmann
3157	Article: Coevolution Theory of the Genetic Code at Age Forty: Pathway to Translation and Synthetic Life by J. Tze-Fei Wong, Siu-Kin Ng, Wai-Kin Mat, Taobo Hu and Hong Xue
3068	Article: A Hypothesis: Life Initiated from Two Genes, as Deduced from the RNA World Hypothesis and the Characteristics of Life-Like Systems by Kunio Kawamura

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