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2011	Inaugural issue released, published as a quarterly journal with two Sections “Life Sciences” and “Physics”
2013	Life covered by Scopus
January 2014	Life has a new Section: “Chemistry”
May 2014	Life has an open peer-review option
May 2014	Life has a new Section: “Hypotheses in the Life Sciences”
November 2014	Life is covered by PubMed and PubMed Central (PMC)

2011	Founding Editor-in-Chief Prof. Dr. Marie-Paul Bassez
2011-	Section Editor-in-Chief Prof. Dr. Helga Stan-Lotter for Section “Life Sciences”
2011-2013	Section Editor-in-Chief Prof. Dr. Antonio Bianconi for Section “Physics”
2014	Editor-in-Chief Prof. Pabulo H. Rampelotto
2014-	Section Editor-in-Chief Prof. Dr. Niles Lehman for Section “Chemistry”
2014-	Section Editor-in-Chief Prof. Dr. Andrew Pohorille for Section “Physics”
2014-	Section Editor-in-Chief Dr. William Bains for Section “Hypotheses in the Life Sciences”
2016-2018	Editor-in-Chief Prof. Dr. David Deamer
2018-	Editor-in-Chief Prof. Dr. Ulrich Muller