Announcements

1. “A Modular and Expandable Ecosystem for Metabolomics Data Annotation in R”
by Johannes Rainer, Andrea Vicini, Liesa Salzer, Jan Stanstrup, Josep M. Badia, Steffen Neumann, Michael A. Stravs, Vinicius Verri Hernandes, Laurent Gatto, Sebastian Gibb et al.
Metabolites 2022, 12(2), 173; https://doi.org/10.3390/metabo12020173
Available online: https://www.mdpi.com/2218-1989/12/2/173

2. “A Checklist for Reproducible Computational Analysis in Clinical Metabolomics Research”
by Xinsong Du, Juan J. Aristizabal-Henao, Timothy J. Garrett, Mathias Brochhausen, William R. Hogan and Dominick J. Lemas
Metabolites 2022, 12(1), 87; https://doi.org/10.3390/metabo12010087
Available online: https://www.mdpi.com/2218-1989/12/1/87

3. “Machine Learning Applied to Omics Datasets Predicts Mortality in Patients with Alcoholic Hepatitis”
by Bei Gao, Tsung-Chin Wu, Sonja Lang, Lu Jiang, Yi Duan, Derrick E. Fouts, Xinlian Zhang, Xin-Ming Tu and Bernd Schnabl
Metabolites 2022, 12(1), 41; https://doi.org/10.3390/metabo12010041
Available online: https://www.mdpi.com/2218-1989/12/1/41

4. “Machine Learning Approaches to Identify Discriminative Signatures of Volatile Organic Compounds (VOCs) from Bacteria and Fungi Using SPME-DART-MS”
by Mehak Arora, Stephen C. Zambrzycki, Joshua M. Levy, Annette Esper, Jennifer K. Frediani, Cassandra L. Quave, Facundo M. Fernández and Rishikesan Kamaleswaran
Metabolites 2022, 12(3), 232; https://doi.org/10.3390/metabo12030232
Available online: https://www.mdpi.com/2218-1989/12/3/232

5. “Evaluating the Accuracy of the QCEIMS Approach for Computational Prediction of Electron Ionization Mass Spectra of Purines and Pyrimidines”
by Jesi Lee, Tobias Kind, Dean Joseph Tantillo, Lee-Ping Wang and Oliver Fiehn
Metabolites 2022, 12(1), 68; https://doi.org/10.3390/metabo12010068
Available online: https://www.mdpi.com/2218-1989/12/1/68

6. “A Multi-Label Classifier for Predicting the Most Appropriate Instrumental Method for the Analysis of Contaminants of Emerging Concern”
by Nikiforos Alygizakis, Vasileios Konstantakos, Grigoris Bouziotopoulos, Evangelos Kormentzas, Jaroslav Slobodnik and Nikolaos S. Thomaidis
Metabolites 2022, 12(3), 199; https://doi.org/10.3390/metabo12030199
Available online: https://www.mdpi.com/2218-1989/12/3/199

7. “JPA: Joint Metabolic Feature Extraction Increases the Depth of Chemical Coverage for LC-MS-Based Metabolomics and Exposomics”
by Jian Guo, Sam Shen, Min Liu, Chenjingyi Wang, Brian Low, Ying Chen, Yaxi Hu, Shipei Xing, Huaxu Yu, Yu Gao et al.
Metabolites 2022, 12(3), 212; https://doi.org/10.3390/metabo12030212
Available online: https://www.mdpi.com/2218-1989/12/3/212

8. “Quantitative Comparison of Statistical Methods for Analyzing Human Metabolomics Data”
by Mir Henglin, Brian L. Claggett, Joseph Antonelli, Mona Alotaibi, Gino Alberto Magalang, Jeramie D. Watrous, Kim A. Lagerborg, Gavin Ovsak, Gabriel Musso, Olga V. Demler et al.
Metabolites 2022, 12(6), 519; https://doi.org/10.3390/metabo12060519
Available online: https://www.mdpi.com/2218-1989/12/6/519

1. “Comparison of Lysis and Detachment Sample Preparation Methods for Cultured Triple-Negative Breast Cancer Cells Using UHPLC–HRMS-Based Metabolomics”
by Blake R. Rushing, Madison Schroder and Susan C. J. Sumner
Metabolites 2022, 12(2), 168; https://doi.org/10.3390/metabo12020168
Available online: https://www.mdpi.com/2218-1989/12/2/168

2. “Photobiomodulation at Different Wavelengths Boosts Mitochondrial Redox Metabolism and Hemoglobin Oxygenation: Lasers vs. Light-Emitting Diodes In Vivo”
by Tyrell Pruitt, Caroline Carter, Xinlong Wang, Anqi Wu and Hanli Liu
Metabolites 2022, 12(2), 103; https://doi.org/10.3390/metabo12020103
Available online: https://www.mdpi.com/2218-1989/12/2/103

3. “Systematic Evaluation of HILIC Stationary Phases for Global Metabolomics of Human Plasma”
*Editor’s Choice Paper
by Farideh Hosseinkhani, Luojiao Huang, Anne-Charlotte Dubbelman, Faisa Guled, Amy C. Harms and Thomas Hankemeier
Metabolites 2022, 12(2), 165; https://doi.org/10.3390/metabo12020165
Available online: https://www.mdpi.com/2218-1989/12/2/165

4. “Patient Stratification in Sepsis: Using Metabolomics to Detect Clinical Phenotypes, Sub-Phenotypes and Therapeutic Response”
by Humma Hussain, Kritchai Vutipongsatorn, Beatriz Jiménez and David B. Antcliffe
Metabolites 2022, 12(5), 376; https://doi.org/10.3390/metabo12050376
Available online: https://www.mdpi.com/2218-1989/12/5/376

5. “Broadband-NIRS System Identifies Epileptic Focus in a Child with Focal Cortical Dysplasia—A Case Study”
by Aikaterini Vezyroglou, Peter Hebden, Isabel De Roever, Rachel Thornton, Subhabrata Mitra, Alan Worley, Mariana Alves, Emma Dean, Judith Helen Cross and Ilias Tachtsidis
Metabolites 2022, 12(3), 260; https://doi.org/10.3390/metabo12030260
Available online: https://www.mdpi.com/2218-1989/12/3/260

6. “MALDI Mass Spectrometry Imaging Highlights Specific Metabolome and Lipidome Profiles in Salivary Gland Tumor Tissues”
by Eduardo Sommella, Emanuela Salviati, Vicky Caponigro, Manuela Grimaldi, Simona Musella, Alessia Bertamino, Luigi Cacace, Remo Palladino, Giuseppe Di Mauro, Federico Marini et al.
Metabolites 2022, 12(6), 530; https://doi.org/10.3390/metabo12060530
Available online: https://www.mdpi.com/2218-1989/12/6/530

7. “Automated Sample Preparation and Data Collection Workflow for High-Throughput In Vitro Metabolomics”
*Editor’s Choice Paper
by Julia M. Malinowska, Taina Palosaari, Jukka Sund, Donatella Carpi, Gavin R. Lloyd, Ralf J. M. Weber, Maurice Whelan and Mark R. Viant
Metabolites 2022, 12(1), 52; https://doi.org/10.3390/metabo12010052
Available online: https://www.mdpi.com/2218-1989/12/1/52

8. “Simultaneous Quantification of Steroid Hormones Using hrLC-MS in Endocrine Tissues of Male Rats and Human Samples”
by Guillermo Bordanaba-Florit, Sebastiaan van Liempd, Diana Cabrera, Félix Royo and Juan Manuel Falcón-Pérez
Metabolites 2022, 12(8), 714; https://doi.org/10.3390/metabo12080714
Available online: https://www.mdpi.com/2218-1989/12/8/714

1. “Mycorrhiza-Tree-Herbivore Interactions: Alterations in Poplar Metabolome and Volatilome”
by Prasath Balaji Sivaprakasam Padmanaban, Maaria Rosenkranz, Peiyuan Zhu, Moritz Kaling, Anna Schmidt, Philippe Schmitt-Kopplin, Andrea Polle and Jörg-Peter Schnitzler
Metabolites 2022, 12(2), 93; https://doi.org/10.3390/metabo12020093
Available online: https://www.mdpi.com/2218-1989/12/2/93

2. “Kinetic Modeling of Saccharomyces cerevisiae Central Carbon Metabolism: Achievements, Limitations, and Opportunities”
by David Lao-Martil, Koen J. A. Verhagen, Joep P. J. Schmitz, Bas Teusink, S. Aljoscha Wahl and Natal A. W. van Riel
Metabolites 2022, 12(1), 74; https://doi.org/10.3390/metabo12010074
Available online: https://www.mdpi.com/2218-1989/12/1/74

3. “Environmental Metabolomics Promises and Achievements in the Field of Aquatic Ecotoxicology: Viewed through the Pharmaceutical Lens”
by Thibaut Dumas, Frédérique Courant, Hélène Fenet and Elena Gomez
Metabolites 2022, 12(2), 186; https://doi.org/10.3390/metabo12020186
Available online: https://www.mdpi.com/2218-1989/12/2/186

4. “Exploring Thermal Sensitivities and Adaptations of Oxidative Phosphorylation Pathways”
by Hélène Lemieux and Pierre U. Blier
Metabolites 2022, 12(4), 360; https://doi.org/10.3390/metabo12040360
Available online: https://www.mdpi.com/2218-1989/12/4/360

5. “Spatially Mapping the Baseline and Bisphenol-A Exposed Daphnia magna Lipidome Using Desorption Electrospray Ionization—Mass Spectrometry”
by Matthew J. Smith, Ralf J. M. Weber and Mark R. Viant
Metabolites 2022, 12(1), 33; https://doi.org/10.3390/metabo12010033
Available online: https://www.mdpi.com/2218-1989/12/1/33

6. “TransDiscovery: Discovering Biotransformation from Human Microbiota by Integrating Metagenomic and Metabolomic Data”
by Donghui Yan, Liu Cao, Muqing Zhou and Hosein Mohimani
Metabolites 2022, 12(2), 119; https://doi.org/10.3390/metabo12020119
Available online: https://www.mdpi.com/2218-1989/12/2/119

7. “Early Biological Modulations Resulting from 1-Week Venlafaxine Exposure of Marine Mussels Mytilus galloprovincialis Determined by a Metabolomic Approach”
by Gaëlle Ramirez, Elena Gomez, Thibaut Dumas, David Rosain, Olivier Mathieu, Hélène Fenet and Frédérique Courant
Metabolites 2022, 12(3), 197; https://doi.org/10.3390/metabo12030197
Available online: https://www.mdpi.com/2218-1989/12/3/197

8. “Amplified Drought and Seasonal Cycle Modulate Quercus pubescens Leaf Metabolome”
by Amélie Saunier, Stéphane Greff, James D. Blande, Caroline Lecareux, Virginie Baldy, Catherine Fernandez and Elena Ormeño
Metabolites 2022, 12(4), 307; https://doi.org/10.3390/metabo12040307
Available online: https://www.mdpi.com/2218-1989/12/4/307

1. “Tea Polyphenols Protect the Mammary Gland of Dairy Cows by Enhancing Antioxidant Capacity and Regulating the TGF-β1/p38/JNK Pathway”
by Ran Xu, Mengran Zhu, Jingwen Cao and Mengyao Guo
Metabolites 2022, 12(11), 1009; https://doi.org/10.3390/metabo12111009
Available online: https://www.mdpi.com/2218-1989/12/11/1009

2. “Prenatal Supplementation in Beef Cattle and Its Effects on Plasma Metabolome of Dams and Calves”
by Fernando José Schalch Junior, Guilherme Henrique Gebim Polizel, Fernando Augusto Correia Queiroz Cançado, Arícia Christofaro Fernandes, Isabela Mortari, Pedro Ratto Lisboa Pires, Heidge Fukumasu, Miguel Henrique de Almeida Santana and Arlindo Saran Netto
Metabolites 2022, 12(4), 347; https://doi.org/10.3390/metabo12040347
Available online: https://www.mdpi.com/2218-1989/12/4/347

3. “Maternal Nutrient Restriction Disrupts Gene Expression and Metabolites Associated with Urea Cycle, Steroid Synthesis, Glucose Homeostasis, and Glucuronidation in Fetal Calf Liver”
by Susumu Muroya, Yi Zhang, Kounosuke Otomaru, Kazunaga Oshima, Ichiro Oshima, Mitsue Sano, Sanggun Roh, Koichi Ojima and Takafumi Gotoh
Metabolites 2022, 12(3), 203; https://doi.org/10.3390/metabo12030203
Available online: https://www.mdpi.com/2218-1989/12/3/203

4. “Cryoprotective Metabolites Are Sourced from Both External Diet and Internal Macromolecular Reserves during Metabolic Reprogramming for Freeze Tolerance in Drosophilid Fly, Chymomyza costata”
by Martin Moos, Jaroslava Korbelová, Tomáš Štětina, Stanislav Opekar, Petr Šimek, Robert Grgac and Vladimír Koštál
Metabolites 2022, 12(2), 163; https://doi.org/10.3390/metabo12020163
Available online: https://www.mdpi.com/2218-1989/12/2/163

5. “Qualitative and Quantitative Effects of Fatty Acids Involved in Heart Diseases”
by Hidenori Moriyama, Jin Endo, Hidehiko Ikura, Hiroki Kitakata, Mizuki Momoi, Yoshiki Shinya, Seien Ko, Genki Ichihara, Takahiro Hiraide, Kohsuke Shirakawa et al.
Metabolites 2022, 12(3), 210; https://doi.org/10.3390/metabo12030210
Available online: https://www.mdpi.com/2218-1989/12/3/210

6. “Production of Hydroxy Fatty Acids, Precursors of γ-Hexalactone, Contributes to the Characteristic Sweet Aroma of Beef”
by Shuji Ueda, Mana Hosoda, Kumi Kasamatsu, Masahiro Horiuchi, Rio Nakabayashi, Bubwoong Kang, Masakazu Shinohara, Hiroki Nakanishi, Takayo Ohto-Nakanishi, Minoru Yamanoue and Yasuhito Shirai
Metabolites 2022, 12(4), 332; https://doi.org/10.3390/metabo12040332
Available online: https://www.mdpi.com/2218-1989/12/4/332

7. “Comparative Metabolomics of Small Molecules Specifically Expressed in the Dorsal or Ventral Marginal Zones in Vertebrate Gastrula”
by Yukako Suzuki, Ryosuke Hayasaka, Masako Hasebe, Satsuki Ikeda, Tomoyoshi Soga, Masaru Tomita, Akiyoshi Hirayama and Hiroki Kuroda
Metabolites 2022, 12(6), 566; https://doi.org/10.3390/metabo12060566
Available online: https://www.mdpi.com/2218-1989/12/6/566

8. “Relationships between Milk and Blood Biochemical Parameters and Metabolic Status in Dairy Cows during Lactation”
by Biljana Andjelić, Radojica Djoković, Marko Cincović, Snežana Bogosavljević-Bošković, Milun Petrović, Jelena Mladenović and Aleksandar Čukić
Metabolites 2022, 12(8), 733; https://doi.org/10.3390/metabo12080733
Available online: https://www.mdpi.com/2218-1989/12/8/733

1. “Unlike Glycerophosphocholine or Choline Chloride, Dietary Phosphatidylcholine Does Not Increase Plasma Trimethylamine-N-Oxide Levels in Sprague-Dawley Rats”
by Bungo Shirouchi, Ayano Fukuda and Taiki Akasaka
Metabolites 2022, 12(1), 64; https://doi.org/10.3390/metabo12010064
Available online: https://www.mdpi.com/2218-1989/12/1/64

2. “Effects of Water Stress, Defoliation and Crop Thinning on Vitis vinifera L. cv. Solaris: Part I: Plant Responses, Fruit Development and Fruit Quality”
by Violetta Aru, Andreas Paul Nittnaus, Klavs Martin Sørensen, Søren Balling Engelsen and Torben Bo Toldam-Andersen
Metabolites 2022, 12(4), 363; https://doi.org/10.3390/metabo12040363
Available online: https://www.mdpi.com/2218-1989/12/4/363

3. “Dietary Alaska Pollock Protein Attenuates the Experimental Colitis Induced by Dextran Sulfate Sodium via Regulation of Gut Microbiota and Its Metabolites in Mice”
by Genki Tanaka, Nozomi Hagihara, Ryota Hosomi, Takaki Shimono, Seiji Kanda, Toshimasa Nishiyama, Munehiro Yoshida and Kenji Fukunaga
Metabolites 2022, 12(1), 44; https://doi.org/10.3390/metabo12010044
Available online: https://www.mdpi.com/2218-1989/12/1/44

4. “Functional Nutrients to Ameliorate Neurogenic Muscle Atrophy”
by Viviana Moresi, Alessandra Renzini, Giorgia Cavioli, Marilia Seelaender, Dario Coletti, Giuseppe Gigli and Alessia Cedola
Metabolites 2022, 12(11), 1149; https://doi.org/10.3390/metabo12111149
Available online: https://www.mdpi.com/2218-1989/12/11/1149

5. “Sulfonation Reactions behind the Fate of White Wine’s Shelf-Life”
by Maria Nikolantonaki, Rémy Romanet, Marianna Lucio, Philippe Schmitt-Kopplin and Régis Gougeon
Metabolites 2022, 12(4), 323; https://doi.org/10.3390/metabo12040323
Available online: https://www.mdpi.com/2218-1989/12/4/323

6. “Stimulation of GLUT4 Glucose Uptake by Anthocyanin-Rich Extract from Black Rice (Oryza sativa L.) via PI3K/Akt and AMPK/p38 MAPK Signaling in C2C12 Cells”
by Shui-Yuan Feng, Shu-Jing Wu, Yun-Ching Chang, Lean-Teik Ng and Sue-Joan Chang
Metabolites 2022, 12(9), 856; https://doi.org/10.3390/metabo12090856
Available online: https://www.mdpi.com/2218-1989/12/9/856

7. “Sugarcane Metabolome Compositional Stability in Pretreatment Processes for NMR Measurements”
by Yasuhiro Date, Chiaki Ishikawa, Makoto Umeda, Yusuke Tarumoto, Megumi Okubo, Yasuaki Tamura and Hiroshi Ono
Metabolites 2022, 12(9), 862; https://doi.org/10.3390/metabo12090862
Available online: https://www.mdpi.com/2218-1989/12/9/862

8. “Carbohydrate Intake and Closed-Loop Insulin Delivery System during Two Subsequent Pregnancies in Type 1 Diabetes”
by Ana Munda, Chiara Kovacic and Drazenka Pongrac Barlovic
Metabolites 2022, 12(11), 1137; https://doi.org/10.3390/metabo12111137
Available online: https://www.mdpi.com/2218-1989/12/11/1137

1. “LC-MS/MS Characterization of Phenolic Metabolites and Their Antioxidant Activities from Australian Native Plants”
by Akhtar Ali, Jeremy J. Cottrell and Frank R. Dunshea
Metabolites 2022, 12(11), 1016; https://doi.org/10.3390/metabo12111016
Available online: https://www.mdpi.com/2218-1989/12/11/1016

2. ”Multi-Omics-Based Discovery of Plant Signaling Molecules”
by Fei Luo, Zongjun Yu, Qian Zhou and Ancheng Huang
Metabolites 2022, 12(1), 76; https://doi.org/10.3390/metabo12010076
Available online: https://www.mdpi.com/2218-1989/12/1/76

3. “Comparative Metabolite Profiling of Wheat Cultivars (Triticum aestivum) Reveals Signatory Markers for Resistance and Susceptibility to Stripe Rust and Aluminium (Al³⁺) Toxicity”
by Manamele D. Mashabela, Lizelle A. Piater, Paul A. Steenkamp, Ian A. Dubery, Fidele Tugizimana and Msizi I. Mhlongo
Metabolites 2022, 12(2), 98; https://doi.org/10.3390/metabo12020098
Available online: https://www.mdpi.com/2218-1989/12/2/98

4. “Computational Metabolomics Tools Reveal Metabolic Reconfigurations Underlying the Effects of Biostimulant Seaweed Extracts on Maize Plants under Drought Stress Conditions”
by Morena M. Tinte, Keabetswe Masike, Paul A. Steenkamp, Johan Huyser, Justin J. J. van der Hooft and Fidele Tugizimana
Metabolites 2022, 12(6), 487; https://doi.org/10.3390/metabo12060487
Available online: https://www.mdpi.com/2218-1989/12/6/487

5. “UHPLC-MS Metabolomic Fingerprinting, Antioxidant, and Enzyme Inhibition Activities of Himantormia lugubris from Antarctica”
by Carlos Areche, Javier Romero Parra, Beatriz Sepulveda, Olimpo García-Beltrán and Mario J. Simirgiotis
Metabolites 2022, 12(6), 560; https://doi.org/10.3390/metabo12060560
Available online: https://www.mdpi.com/2218-1989/12/6/560

6. “Profiling of Volatile Organic Compounds from Four Plant Growth-Promoting Rhizobacteria by SPME–GC–MS: A Metabolomics Study”
by Msizi I. Mhlongo, Lizelle A. Piater and Ian A. Dubery
Metabolites 2022, 12(8), 763; https://doi.org/10.3390/metabo12080763
Available online: https://www.mdpi.com/2218-1989/12/8/763

7. “Metabolites in Cherry Buds to Detect Winter Dormancy”
by Frank-M. Chmielewski and Klaus-P. Götz
Metabolites 2022, 12(3), 247; https://doi.org/10.3390/metabo12030247
Available online: https://www.mdpi.com/2218-1989/12/3/247

8. “The Metabolic Profile of Anchusa officinalis L. Differs According to Its Associated Arbuscular Mycorrhizal Fungi”
by Evangelia Tsiokanos, Annalisa Cartabia, Nikolaos Tsafantakis, Ismahen Lalaymia, Aikaterini Termentzi, Maria Miguel, Stéphane Declerck and Nikolas Fokialakis
Metabolites 2022, 12(7), 573; https://doi.org/10.3390/metabo12070573
Available online: https://www.mdpi.com/2218-1989/12/7/573

1. “NMR Metabolomics Reveal Urine Markers of Microbiome Diversity and Identify Benzoate Metabolism as a Mediator between High Microbial Alpha Diversity and Metabolic Health”
by Johannes Hertel, Daniel Fässler, Almut Heinken, Frank U. Weiß, Malte Rühlemann, Corinna Bang, Andre Franke, Kathrin Budde, Ann-Kristin Henning, Astrid Petersmann et al.
Metabolites 2022, 12(4), 308; https://doi.org/10.3390/metabo12040308
Available online: https://www.mdpi.com/2218-1989/12/4/308

2. “Solid-State Fermented Okara with Aspergillus spp. Improves Lipid Metabolism and High-Fat Diet Induced Obesity”
by Natsumi Ichikawa, Li Shiuan Ng, Saneyuki Makino, Luo Lin Goh, Yun Jia Lim, Ferdinandus, Hiroyuki Sasaki, Shigenobu Shibata and Chi-Lik Ken Lee
Metabolites 2022, 12(3), 198; https://doi.org/10.3390/metabo12030198
Available online: https://www.mdpi.com/2218-1989/12/3/198

3. “The Interaction between the Gut Microbiome and Bile Acids in Cardiometabolic Diseases”
by Cengiz Callender, Ilias Attaye and Max Nieuwdorp
Metabolites 2022, 12(1), 65; https://doi.org/10.3390/metabo12010065
Available online: https://www.mdpi.com/2218-1989/12/1/65

4. “New Kids on the Block: Bile Salt Conjugates of Microbial Origin”
by Ümran Ay, Martin Leníček, Arno Classen, Steven W. M. Olde Damink, Carsten Bolm and Frank G. Schaap
Metabolites 2022, 12(2), 176; https://doi.org/10.3390/metabo12020176
Available online: https://www.mdpi.com/2218-1989/12/2/176

5. “Farnesoid X Receptor, Bile Acid Metabolism, and Gut Microbiota”
by Hideki Mori, Gianluca Svegliati Baroni, Marco Marzioni, Francesca Di Nicola, Pierangelo Santori, Luca Maroni, Ludovico Abenavoli and Emidio Scarpellini
Metabolites 2022, 12(7), 647; https://doi.org/10.3390/metabo12070647
Available online: https://www.mdpi.com/2218-1989/12/7/647

6. “Identification of New Natural Sources of Flavour and Aroma Metabolites from Solid-State Fermentation of Agro-Industrial By-Products”
by Melodie A. Lindsay, Ninna Granucci, David R. Greenwood and Silas G. Villas-Boas
Metabolites 2022, 12(2), 157; https://doi.org/10.3390/metabo12020157
Available online: https://www.mdpi.com/2218-1989/12/2/157

7. “Non-Invasive Monitoring of Inflammation in Inflammatory Bowel Disease Patients during Prolonged Exercise via Exhaled Breath Volatile Organic Compounds”
by Ben Henderson, Joris Meurs, Carlijn R. Lamers, Guilherme Lopes Batista, Dušan Materić, Carlo G. Bertinetto, Coen C. W. G. Bongers, Rupert Holzinger, Frans J. M. Harren, Jeroen J. Jansen et al.
Metabolites 2022, 12(3), 224; https://doi.org/10.3390/metabo12030224
Available online: https://www.mdpi.com/2218-1989/12/3/224

8. “Microbial Interactions in Kombucha through the Lens of Metabolomics”
by Thierry Tran, Chloé Roullier-Gall, François Verdier, Antoine Martin, Philippe Schmitt-Kopplin, Hervé Alexandre, Cosette Grandvalet and Raphaëlle Tourdot-Maréchal
Metabolites 2022, 12(3), 235; https://doi.org/10.3390/metabo12030235
Available online: https://www.mdpi.com/2218-1989/12/3/235

1. “Glutamate Efflux across the Blood–Brain Barrier: New Perspectives on the Relationship between Depression and the Glutamatergic System”
by Benjamin Fredrick Gruenbaum, Alexander Zlotnik, Amit Frenkel, Ilya Fleidervish and Matthew Boyko
Metabolites 2022, 12(5), 459; https://doi.org/10.3390/metabo12050459
Available online: https://www.mdpi.com/2218-1989/12/5/459

2. “In Vitro Metabolism of Helenalin Acetate and 11α,13-Dihydrohelenalin Acetate: Natural Sesquiterpene Lactones from Arnica”
by Franziska M. Jürgens, Matthias Behrens, Hans-Ulrich Humpf, Sara M. Robledo and Thomas J. Schmidt
Metabolites 2022, 12(1), 88; https://doi.org/10.3390/metabo12010088
Available online: https://www.mdpi.com/2218-1989/12/1/88

3. “Lipidomics in Understanding Pathophysiology and Pharmacologic Effects in Inflammatory Diseases: Considerations for Drug Development”
by Kabir Ahluwalia, Brandon Ebright, Kingsley Chow, Priyal Dave, Andrew Mead, Roy Poblete, Stan G. Louie and Isaac Asante
Metabolites 2022, 12(4), 333; https://doi.org/10.3390/metabo12040333
Available online: https://www.mdpi.com/2218-1989/12/4/333

4. “The Glycobiology of Pulmonary Arterial Hypertension”
by Shia Vang, Phillip Cochran, Julio Sebastian Domingo, Stefanie Krick and Jarrod Wesley Barnes
Metabolites 2022, 12(4), 316; https://doi.org/10.3390/metabo12040316
Available online: https://www.mdpi.com/2218-1989/12/4/316

5. “Availability and Metabolic Fate of Olive Phenolic Alcohols Hydroxytyrosol and Tyrosol in the Human GI Tract Simulated by the In Vitro GIDM–Colon Model”
by Maria Eleni Sakavitsi, Annelies Breynaert, Theodora Nikou, Stef Lauwers, Luc Pieters, Nina Hermans and Maria Halabalaki
Metabolites 2022, 12(5), 391; https://doi.org/10.3390/metabo12050391
Available online: https://www.mdpi.com/2218-1989/12/5/391

6. “Infection Biomarkers Based on Metabolomics”
by Rúben Araújo, Luís F. N. Bento, Tiago A. H. Fonseca, Cristiana P. Von Rekowski, Bernardo Ribeiro da Cunha and Cecília R. C. Calado
Metabolites 2022, 12(2), 92; https://doi.org/10.3390/metabo12020092
Available online: https://www.mdpi.com/2218-1989/12/2/92

7. “Effects of Selen on the Antidepressant-like Activity of Agents Affecting the Adenosinergic Neurotransmission”
by Aleksandra Szopa, Mariola Herbet, Ewa Poleszak, Karolina Bogatko, Marta Ostrowska-Leśko, Katarzyna Świąder, Jarosław Szponar and Anna Serefko
Metabolites 2022, 12(7), 586; https://doi.org/10.3390/metabo12070586
Available online: https://www.mdpi.com/2218-1989/12/7/586

8. “Human Hepatocyte 4-Acetoxy-N,N-Diisopropyltryptamine Metabolite Profiling by Reversed-Phase Liquid Chromatography Coupled with High-Resolution Tandem Mass Spectrometry”
by Sara Malaca, Marilyn A. Huestis, Leonardo Lattanzio, Luigi T. Marsella, Adriano Tagliabracci, Jeremy Carlier and Francesco P. Busardò
Metabolites 2022, 12(8), 705; https://doi.org/10.3390/metabo12080705
Available online: https://www.mdpi.com/2218-1989/12/8/705

1. “Metabolomic Studies in Inner Ear Pathologies”
by Luc Boullaud, Hélène Blasco, Thuy-Trân Trinh and David Bakhos
Metabolites 2022, 12(3), 214; https://doi.org/10.3390/metabo12030214
Available online: https://www.mdpi.com/2218-1989/12/3/214

2. “Biomarkers of Endothelial Damage in Distinct Phases of Multisystem Inflammatory Syndrome in Children”
by Monica Gelzo, Antonietta Giannattasio, Marco Maglione, Stefania Muzzica, Carolina D’Anna, Filippo Scialò, Thaililja Gagliardo, Michela Grieco, Vincenzo Tipo and Giuseppe Castaldo
Metabolites 2022, 12(8), 680; https://doi.org/10.3390/metabo12080680
Available online: https://www.mdpi.com/2218-1989/12/8/680

3. “Modulation of Fecal Metabolites by Heat Stress and Diet, and Their Association with Inflammation and Leaky Gut Markers in Dairy Cows”
by Alexis Ruiz-González, Daniel Enrique Rico and Jorge Eduardo Rico
Metabolites 2022, 12(2), 142; https://doi.org/10.3390/metabo12020142
Available online: https://www.mdpi.com/2218-1989/12/2/142

4. “Effects of Acute and Chronic Resistance Exercise on the Skeletal Muscle Metabolome”
by Sebastian Gehlert, Patrick Weinisch, Werner Römisch-Margl, Richard T. Jaspers, Anna Artati, Jerzy Adamski, Kenneth A. Dyar, Thorben Aussieker, Daniel Jacko, Wilhelm Bloch et al.
Metabolites 2022, 12(5), 445; https://doi.org/10.3390/metabo12050445
Available online: https://www.mdpi.com/2218-1989/12/5/445

5. “Metabolomic Analysis of Severe Osteoarthritis in a Spanish Population of Women Compared to Healthy and Osteoporotic Subjects”
by Clara Pertusa, Damián Mifsut, José Manuel Morales, Juan J. Tarín, Antonio Cano, Daniel Monleón and Miguel Ángel García-Pérez
Metabolites 2022, 12(8), 677; https://doi.org/10.3390/metabo12080677
Available online: https://www.mdpi.com/2218-1989/12/8/677

6. “Co-Expression Network and Integrative Analysis of Metabolome and Transcriptome Uncovers Biological Pathways for Fertility in Beef Heifers”
by Priyanka Banerjee, Soren P. Rodning, Wellison J. S. Diniz and Paul W. Dyce
Metabolites 2022, 12(8), 708; https://doi.org/10.3390/metabo12080708
Available online: https://www.mdpi.com/2218-1989/12/8/708

7. “Estimated Renal Metabolomics at Reperfusion Predicts One-Year Kidney Graft Function”
by Thomas Verissimo, Anna Faivre, Sebastian Sgardello, Maarten Naesens, Sophie de Seigneux, Gilles Criton and David Legouis
Metabolites 2022, 12(1), 57; https://doi.org/10.3390/metabo12010057
Available online: https://www.mdpi.com/2218-1989/12/1/57

8. “Sex Dimorphism in the Metabolome of Metabolic Syndrome in Morbidly Obese Individuals”
by Serena Pisoni, Vannina G. Marrachelli, Jose M. Morales, Sabrina Maestrini, Anna M. Di Blasio and Daniel Monleón
Metabolites 2022, 12(5), 419; https://doi.org/10.3390/metabo12050419
Available online: https://www.mdpi.com/2218-1989/12/5/419

1. “Gut Microbiota Metabolites in Major Depressive Disorder—Deep Insights into Their Pathophysiological Role and Potential Translational Applications”
by Miguel A. Ortega, Miguel Angel Alvarez-Mon, Cielo García-Montero, Oscar Fraile-Martinez, Luis G. Guijarro, Guillermo Lahera, Jorge Monserrat, Paula Valls, Fernando Mora, Roberto Rodríguez-Jiménez et al.
Metabolites 2022, 12(1), 50; https://doi.org/10.3390/metabo12010050
Available online: https://www.mdpi.com/2218-1989/12/1/50

2. “Nonalcoholic Fatty Liver Disease and Endocrine Axes—A Scoping Review”
by Madalena Von-Hafe, Marta Borges-Canha, Catarina Vale, Ana Rita Leite, João Sérgio Neves, Davide Carvalho and Adelino Leite-Moreira
Metabolites 2022, 12(4), 298; https://doi.org/10.3390/metabo12040298
Available online: https://www.mdpi.com/2218-1989/12/4/298

3. “Involvement of TauT/SLC6A6 in Taurine Transport at the Blood–Testis Barrier”
by Yoshiyuki Kubo, Sakiko Ishizuka, Takeru Ito, Daisuke Yoneyama, Shin-ichi Akanuma and Ken-ichi Hosoya
Metabolites 2022, 12(1), 66; https://doi.org/10.3390/metabo12010066
Available online: https://www.mdpi.com/2218-1989/12/1/66

4. “The Sensory Mechanisms of Nutrient-Induced GLP-1 Secretion”
by Anna Pii Hjørne, Ida Marie Modvig and Jens Juul Holst
Metabolites 2022, 12(5), 420; https://doi.org/10.3390/metabo12050420
Available online: https://www.mdpi.com/2218-1989/12/5/420

5. “Taurine Ameliorates Streptozotocin-Induced Diabetes by Modulating Hepatic Glucose Metabolism and Oxidative Stress in Mice”
by Shigeru Murakami, Kohei Funahashi, Natsuki Tamagawa, Ma Ning and Takashi Ito
Metabolites 2022, 12(6), 524; https://doi.org/10.3390/metabo12060524
Available online: https://www.mdpi.com/2218-1989/12/6/524

6. “Central Taurine Attenuates Hyperthermia and Isolation Stress Behaviors Augmented by Corticotropin-Releasing Factor with Modifying Brain Amino Acid Metabolism in Neonatal Chicks”
by Mohamed Z. Elhussiny, Phuong V. Tran, Yuriko Tsuru, Shogo Haraguchi, Elizabeth R. Gilbert, Mark A. Cline, Takashi Bungo, Mitsuhiro Furuse and Vishwajit S. Chowdhury
Metabolites 2022, 12(1), 83; https://doi.org/10.3390/metabo12010083
Available online: https://www.mdpi.com/2218-1989/12/1/83

7. “How Gut Microbes Nurture Intestinal Stem Cells: A Drosophila Perspective”
by Constantina Neophytou and Chrysoula Pitsouli
Metabolites 2022, 12(2), 169; https://doi.org/10.3390/metabo12020169
Available online: https://www.mdpi.com/2218-1989/12/2/169

8. “Colon Cancer: From Epidemiology to Prevention”
by Kyriaki Katsaounou, Elpiniki Nicolaou, Paris Vogazianos, Cameron Brown, Marios Stavrou, Savvas Teloni, Pantelis Hatzis, Agapios Agapiou, Elisavet Fragkou, Georgios Tsiaoussis et al.
Metabolites 2022, 12(6), 499; https://doi.org/10.3390/metabo12060499
Available online: https://www.mdpi.com/2218-1989/12/6/499