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Announcements
8 June 2023
Metabolites | Issue Cover Articles in 2021
The articles below have been selected as 2021 Issue Cover Articles by the Editorial Office of Metabolites (ISSN: 2218-1989). These articles are from multiple fields within the scope of Metabolites, and we hope they can provide insights and references for scholars in related fields.
1. “Metabolic Dynamics of In Vitro CD8+ T Cell Activation” |
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2. “Maternal Metabolome in Pregnancy and Childhood Asthma or Recurrent Wheeze in the Vitamin D Antenatal Asthma Reduction Trial” |
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3. “Quantitative Assessment of Occipital Metabolic and Energetic Changes in Parkinson’s Patients, Using In Vivo 31P MRS-Based Metabolic Imaging at 7T” |
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4. “Specialized Metabolites from Ribosome Engineered Strains of Streptomyces clavuligerus” |
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5. “Metabolic View on Human Healthspan: A Lipidome-Wide Association Study” |
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6. “General Unified Microbiome Profiling Pipeline (GUMPP) for Large Scale, Streamlined and Reproducible Analysis of Bacterial 16S rRNA Data to Predicted Microbial Metagenomes, Enzymatic Reactions and Metabolic Pathways” |
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7. “Lipidomic Analysis to Assess Oxidative Stress in Acute Coronary Syndrome and Acute Stroke Patients” |
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8. “Do Mass Spectrometry-Derived Metabolomics Improve the Prediction of Pregnancy-Related Disorders? Findings from a UK Birth Cohort with Independent Validation” |
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9. “Analysis of Metabolic Markers in Patients with Chronic Heart Failure Before and After LVAD Implantation” |
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10. “Dynamics in Anemia Development and Dysregulation of Iron Homeostasis in Hospitalized Patients with COVID-19” |
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11. “Cord Blood Metabolome and BMI Trajectory from Birth to Adolescence: A Prospective Birth Cohort Study on Early Life Biomarkers of Persistent Obesity” |
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12. “Plasma Metabolome Normalization in Rheumatoid Arthritis Following Initiation of Methotrexate and the Identification of Metabolic Biomarkers of Efficacy” |
16 May 2023
Meet Us at the 19th Annual International Conference of the Metabolomics Society, 18–22 June 2023, Niagara Falls, Ontario, Canada

Conference: 19th Annual International Conference of the Metabolomics Society
Date: 18–22 June 2023
Place: Niagara Falls Convention Centre, 6815 Stanley Avenue, Niagara Falls, Ontario, Canada L2G 3Y9
Booth: #T12
MDPI will be attending the 19th Annual International Conference of the Metabolomics Society, which will be held from 18 to 22 June 2023 in downtown Niagara Falls, Canada, at the Niagara Falls Convention Centre.
The conference is the official annual meeting of the Metabolomics Society, and the largest metabolomics meeting worldwide. It will cover the major scientific themes of: technology advances; computational metabolomics, statistics, and bioinformatics; metabolomics in health and disease; and metabolomics of plants, food, environment and microbes. A special theme for this conference will focus on mental health, drug addiction and medicinal cannabis. The scientific program will include plenary and keynote talks, three parallel scientific sessions, interactive poster sessions, sponsor lunches, other networking events and a specially organized parallel session to promote metabolomics research in industry. A strong line-up of both introductory and advanced workshops will take place on Sunday, 18 June, and the morning of Monday, 19 June. To complement the exciting scientific program, the conference will offer a welcome reception, vibrant early career events, a conference dinner and other engaging social activities.
The following MDPI journals will be represented:
- Metabolites;
- Agronomy;
- Antioxidants;
- Applied Biosciences;
- BioMed;
- BioMedInformatics;
- Biomolecules;
- Cancers;
- Cells;
- Children;
- CIMB;
- Diseases;
- Foods;
- Genes;
- JPM;
- Nutrients;
- Plants.
Please do not hesitate to reach out (metabolites@mdpi.com) if you plan on attending this conference. Our delegates look forward to meeting you in person and answering any questions that you might have.
For more information about the conference, please visit the following website: https://www.metabolomics2023.org/.
10 May 2023
Meet Us at the ATS (American Thoracic Society) Conference 2023, 21–23 May 2023, Washington DC, USA

Conference: ATS (American Thoracic Society) Conference 2023
Date: 21–23 May 2023
Location: Washington DC, USA
MDPI will be attending ATS 2023 as an exhibitor; we welcome researchers from different backgrounds to visit and share their latest ideas with us.
This conference has been organized by the American Thoracic Society, and it will showcase the latest advances and discoveries in respiratory science, patient care and global respiratory health. At the conference, specialists will share and discuss the latest research and its applications to clinical, basic, and translational science in pulmonary, critical care, and sleep medicine.
The following MDPI journals will be represented:
- JCM;
- Medicina;
- Clinics and Practice;
- JPM;
- Cancers;
- Medicines;
- Healthcare;
- Metabolites;
- Children;
- Brain Sciences.
If you are planning to attend this conference, please do not hesitate to talk with us online. Our delegates look forward to meeting you in person at booth #2606, and answering any questions that you may have. For more information about the conference, please visit the following website: https://conference.thoracic.org/.
20 April 2023
Metabolites | Hot Topic Papers Published in 2022 in the “Advances in Metabolomics” Section
1. “Metabolomics and the Multi-Omics View of Cancer”
by David Wishart
Metabolites 2022, 12(2), 154; https://doi.org/10.3390/metabo12020154
Available online: https://www.mdpi.com/2218-1989/12/2/154
2. “Signatures of Mitochondrial Dysfunction and Impaired Fatty Acid Metabolism in Plasma of Patients with Post-Acute Sequelae of COVID-19 (PASC)”
by Vamsi P. Guntur, Travis Nemkov, Esther de Boer, Michael P. Mohning, David Baraghoshi, Francesca I. Cendali, Inigo San-Millán, Irina Petrache and Angelo D’Alessandro
Metabolites 2022, 12(11), 1026; https://doi.org/10.3390/metabo12111026
Available online: https://www.mdpi.com/2218-1989/12/11/1026
3. “Evaluation of Syrosingopine, an MCT Inhibitor, as Potential Modulator of Tumor Metabolism and Extracellular Acidification”
by Chloe Buyse, Nicolas Joudiou, Aude Warscotte, Elena Richiardone, Lionel Mignion, Cyril Corbet and Bernard Gallez
Metabolites 2022, 12(6), 557; https://doi.org/10.3390/metabo12060557
Available online: https://www.mdpi.com/2218-1989/12/6/557
4. “Vertical Transfer of Metabolites Detectable from Newborn’s Dried Blood Spot Samples Using UPLC-MS: A Chemometric Study”
by Alessandra Olarini, Madeleine Ernst, Gözde Gürdeniz, Min Kim, Nicklas Brustad, Klaus Bønnelykke, Arieh Cohen, David Hougaard, Jessica Lasky-Su, Hans Bisgaard et al.
Metabolites 2022, 12(2), 94; https://doi.org/10.3390/metabo12020094
Available online: https://www.mdpi.com/2218-1989/12/2/94
5. “Optimisation of the HS-SPME/GC-MS Approach by Design of Experiments Combined with Chemometrics for the Classification of Cretan Virgin Olive Oils”
by Artemis Lioupi, Ioannis Sampsonidis, Christina Virgiliou, Vassiliki T. Papoti, Kyriaki G. Zinoviadou, Apostolos Spyros and Georgios Theodoridis
Metabolites 2022, 12(2), 114; https://doi.org/10.3390/metabo12020114
Available online: https://www.mdpi.com/2218-1989/12/2/114
6. “Optimization of LC-MS2 Data Acquisition Parameters for Molecular Networking Applied to Marine Natural Products”
by Sam Afoullouss, Agata Balsam, A. Louise Allcock and Olivier P. Thomas
Metabolites 2022, 12(3), 245; https://doi.org/10.3390/metabo12030245
Available online: https://www.mdpi.com/2218-1989/12/3/245
7. “Camu-Camu Reduces Obesity and Improves Diabetic Profiles of Obese and Diabetic Mice: A Dose-Ranging Study”
by Anne Abot, Amandine Brochot, Nicolas Pomié, Eve Wemelle, Céline Druart, Marion Régnier, Nathalie M. Delzenne, Willem M. de Vos, Claude Knauf and Patrice D. Cani
Metabolites 2022, 12(4), 301; https://doi.org/10.3390/metabo12040301
Available online: https://www.mdpi.com/2218-1989/12/4/301
8. “Mendelian Randomization Analysis Identifies Blood Tyrosine Levels as a Biomarker of Non-Alcoholic Fatty Liver Disease”
by Émilie Gobeil, Ina Maltais-Payette, Nele Taba, Francis Brière, Nooshin Ghodsian, Erik Abner, Jérôme Bourgault, Eloi Gagnon, Hasanga D. Manikpurage, Christian Couture et al.
Metabolites 2022, 12(5), 440; https://doi.org/10.3390/metabo12050440
Available online: https://www.mdpi.com/2218-1989/12/5/440
20 April 2023
Metabolites | Hot Topic Papers Published in 2021 in the “Advances in Metabolomics” Section
1. “Gut Microbiota Dysbiosis Is Associated with Elevated Bile Acids in Parkinson’s Disease”
by Peipei Li, Bryan A. Killinger, Elizabeth Ensink, Ian Beddows, Ali Yilmaz, Noah Lubben, Jared Lamp, Meghan Schilthuis, Irving E. Vega, Randy Woltjer et al.
Metabolites 2021, 11(1), 29; https://doi.org/10.3390/metabo11010029
Available online: https://www.mdpi.com/2218-1989/11/1/29
2. “Metabolomics and Lipidomics: Expanding the Molecular Landscape of Exercise Biology”
*Editor’s Choice Paper
by Mehdi R. Belhaj, Nathan G. Lawler and Nolan J. Hoffman
Metabolites 2021, 11(3), 151; https://doi.org/10.3390/metabo11030151
Available online: https://www.mdpi.com/2218-1989/11/3/151
3. “Salivary Metabolomics for Diagnosis and Monitoring Diseases: Challenges and Possibilities”
by Eelis Hyvärinen, Minttu Savolainen, Jopi J. W. Mikkonen and Arja M. Kullaa
Metabolites 2021, 11(9), 587; https://doi.org/10.3390/metabo11090587
Available online: https://www.mdpi.com/2218-1989/11/9/587
4. “Optical Microscopy-Guided Laser Ablation Electrospray Ionization Ion Mobility Mass Spectrometry: Ambient Single Cell Metabolomics with Increased Confidence in Molecular Identification”
*Editor’s Choice Paper
by Michael J. Taylor, Sara Mattson, Andrey Liyu, Sylwia A. Stopka, Yehia M. Ibrahim, Akos Vertes and Christopher R. Anderton
Metabolites 2021, 11(4), 200; https://doi.org/10.3390/metabo11040200
Available online: https://www.mdpi.com/2218-1989/11/4/200
5. “Metabolomics Diagnosis of COVID-19 from Exhaled Breath Condensate”
by Elettra Barberis, Elia Amede, Shahzaib Khoso, Luigi Castello, Pier Paolo Sainaghi, Mattia Bellan, Piero Emilio Balbo, Giuseppe Patti, Diego Brustia, Mara Giordano et al.
Metabolites 2021, 11(12), 847; https://doi.org/10.3390/metabo11120847
Available online: https://www.mdpi.com/2218-1989/11/12/847
6. “Plasma Metabolome and Lipidome Associations with Type 2 Diabetes and Diabetic Nephropathy”
by Yan Ming Tan, Yan Gao, Guoshou Teo, Hiromi W. L. Koh, E Shyong Tai, Chin Meng Khoo, Kwok Pui Choi, Lei Zhou and Hyungwon Choi
Metabolites 2021, 11(4), 228; https://doi.org/10.3390/metabo11040228
Available online: https://www.mdpi.com/2218-1989/11/4/228
7. “Contribution of Metabolomics to the Understanding of NAFLD and NASH Syndromes: A Systematic Review”
by Cristina Piras, Antonio Noto, Luciano Ibba, Martino Deidda, Vassilios Fanos, Sandro Muntoni, Vera Piera Leoni and Luigi Atzori
Metabolites 2021, 11(10), 694; https://doi.org/10.3390/metabo11100694
Available online: https://www.mdpi.com/2218-1989/11/10/694
8. “Metabolomics Studies in Psoriatic Disease: A Review”
by John Koussiouris, Nikita Looby, Melanie Anderson, Vathany Kulasingam and Vinod Chandran
Metabolites 2021, 11(6), 375; https://doi.org/10.3390/metabo11060375
Available online: https://www.mdpi.com/2218-1989/11/6/375
13 April 2023
Metabolites | Hot Topic Papers Published in 2022 in the “Endocrinology and Clinical Metabolic Research” Section
1. “Salivary Metabolomics for Oral Squamous Cell Carcinoma Diagnosis: A Systematic Review”
by Kacper Nijakowski, Dawid Gruszczyński, Dariusz Kopała and Anna Surdacka
Metabolites 2022, 12(4), 294; https://doi.org/10.3390/metabo12040294
Available online: https://www.mdpi.com/2218-1989/12/4/294
2. “Cardiovascular and Renal Effectiveness of GLP-1 Receptor Agonists vs. Other Glucose-Lowering Drugs in Type 2 Diabetes: A Systematic Review and Meta-Analysis of Real-World Studies”
by Irene Caruso, Angelo Cignarelli, Gian Pio Sorice, Annalisa Natalicchio, Sebastio Perrini, Luigi Laviola and Francesco Giorgino
Metabolites 2022, 12(2), 183; https://doi.org/10.3390/metabo12020183
Available online: https://www.mdpi.com/2218-1989/12/2/183
3. “The Role of Nutraceutical Containing Polyphenols in Diabetes Prevention”
by Iva Fernandes, Joana Oliveira, Aryane Pinho and Eugenia Carvalho
Metabolites 2022, 12(2), 184; https://doi.org/10.3390/metabo12020184
Available online: https://www.mdpi.com/2218-1989/12/2/184
4. “Emerging Role of Nuclear Receptors for the Treatment of NAFLD and NASH”
by Ryan D. Welch, Cyrielle Billon, McKenna Losby, Gonzalo Bedia-Diaz, Yuanying Fang, Amer Avdagic, Bahaa Elgendy, Thomas P. Burris and Kristine Griffett
Metabolites 2022, 12(3), 238; https://doi.org/10.3390/metabo12030238
Available online: https://www.mdpi.com/2218-1989/12/3/238
5. “Extracellular Matrix in Heart Disease: Focus on Circulating Collagen Type I and III Derived Peptides as Biomarkers of Myocardial Fibrosis and Their Potential in the Prognosis of Heart Failure: A Concise Review”
by Asparuh Nikolov and Nikola Popovski
Metabolites 2022, 12(4), 297; https://doi.org/10.3390/metabo12040297
Available online: https://www.mdpi.com/2218-1989/12/4/297
6. “Fetuin-A in Activated Liver Macrophages Is a Key Feature of Non-Alcoholic Steatohepatitis”
by Quentin Etienne, Valérie Lebrun, Mina Komuta, Benoît Navez, Jean-Paul Thissen, Isabelle A. Leclercq and Nicolas Lanthier
Metabolites 2022, 12(7), 625; https://doi.org/10.3390/metabo12070625
Available online: https://www.mdpi.com/2218-1989/12/7/625
7. “Assessment of Fruit and Vegetables Intake with Biomarkers in Children and Adolescents and Their Level of Validation: A Systematic Review”
by Li Yuan, Samuel Muli, Inge Huybrechts, Ute Nöthlings, Wolfgang Ahrens, Augustin Scalbert and Anna Floegel
Metabolites 2022, 12(2), 126; https://doi.org/10.3390/metabo12020126
Available online: https://www.mdpi.com/2218-1989/12/2/126
8. “The Intestinal Barrier—Shielding the Body from Nano- and Microparticles in Our Diet”
by Marlene Schwarzfischer and Gerhard Rogler
Metabolites 2022, 12(3), 223; https://doi.org/10.3390/metabo12030223
Available online: https://www.mdpi.com/2218-1989/12/3/223
13 April 2023
Metabolites | Hot Topic Papers Published in 2022 in the “Bioinformatics and Data Analysis” Section
1. “A Modular and Expandable Ecosystem for Metabolomics Data Annotation in R”
by Johannes Rainer, Andrea Vicini, Liesa Salzer, Jan Stanstrup, Josep M. Badia, Steffen Neumann, Michael A. Stravs, Vinicius Verri Hernandes, Laurent Gatto, Sebastian Gibb et al.
Metabolites 2022, 12(2), 173; https://doi.org/10.3390/metabo12020173
Available online: https://www.mdpi.com/2218-1989/12/2/173
2. “A Checklist for Reproducible Computational Analysis in Clinical Metabolomics Research”
by Xinsong Du, Juan J. Aristizabal-Henao, Timothy J. Garrett, Mathias Brochhausen, William R. Hogan and Dominick J. Lemas
Metabolites 2022, 12(1), 87; https://doi.org/10.3390/metabo12010087
Available online: https://www.mdpi.com/2218-1989/12/1/87
3. “Machine Learning Applied to Omics Datasets Predicts Mortality in Patients with Alcoholic Hepatitis”
by Bei Gao, Tsung-Chin Wu, Sonja Lang, Lu Jiang, Yi Duan, Derrick E. Fouts, Xinlian Zhang, Xin-Ming Tu and Bernd Schnabl
Metabolites 2022, 12(1), 41; https://doi.org/10.3390/metabo12010041
Available online: https://www.mdpi.com/2218-1989/12/1/41
4. “Machine Learning Approaches to Identify Discriminative Signatures of Volatile Organic Compounds (VOCs) from Bacteria and Fungi Using SPME-DART-MS”
by Mehak Arora, Stephen C. Zambrzycki, Joshua M. Levy, Annette Esper, Jennifer K. Frediani, Cassandra L. Quave, Facundo M. Fernández and Rishikesan Kamaleswaran
Metabolites 2022, 12(3), 232; https://doi.org/10.3390/metabo12030232
Available online: https://www.mdpi.com/2218-1989/12/3/232
5. “Evaluating the Accuracy of the QCEIMS Approach for Computational Prediction of Electron Ionization Mass Spectra of Purines and Pyrimidines”
by Jesi Lee, Tobias Kind, Dean Joseph Tantillo, Lee-Ping Wang and Oliver Fiehn
Metabolites 2022, 12(1), 68; https://doi.org/10.3390/metabo12010068
Available online: https://www.mdpi.com/2218-1989/12/1/68
6. “A Multi-Label Classifier for Predicting the Most Appropriate Instrumental Method for the Analysis of Contaminants of Emerging Concern”
by Nikiforos Alygizakis, Vasileios Konstantakos, Grigoris Bouziotopoulos, Evangelos Kormentzas, Jaroslav Slobodnik and Nikolaos S. Thomaidis
Metabolites 2022, 12(3), 199; https://doi.org/10.3390/metabo12030199
Available online: https://www.mdpi.com/2218-1989/12/3/199
7. “JPA: Joint Metabolic Feature Extraction Increases the Depth of Chemical Coverage for LC-MS-Based Metabolomics and Exposomics”
by Jian Guo, Sam Shen, Min Liu, Chenjingyi Wang, Brian Low, Ying Chen, Yaxi Hu, Shipei Xing, Huaxu Yu, Yu Gao et al.
Metabolites 2022, 12(3), 212; https://doi.org/10.3390/metabo12030212
Available online: https://www.mdpi.com/2218-1989/12/3/212
8. “Quantitative Comparison of Statistical Methods for Analyzing Human Metabolomics Data”
by Mir Henglin, Brian L. Claggett, Joseph Antonelli, Mona Alotaibi, Gino Alberto Magalang, Jeramie D. Watrous, Kim A. Lagerborg, Gavin Ovsak, Gabriel Musso, Olga V. Demler et al.
Metabolites 2022, 12(6), 519; https://doi.org/10.3390/metabo12060519
Available online: https://www.mdpi.com/2218-1989/12/6/519
13 April 2023
Metabolites | Hot Topic Papers Published in 2022 in the “Metabolomic Profiling Technology” Section
1. “Comparison of Lysis and Detachment Sample Preparation Methods for Cultured Triple-Negative Breast Cancer Cells Using UHPLC–HRMS-Based Metabolomics”
by Blake R. Rushing, Madison Schroder and Susan C. J. Sumner
Metabolites 2022, 12(2), 168; https://doi.org/10.3390/metabo12020168
Available online: https://www.mdpi.com/2218-1989/12/2/168
2. “Photobiomodulation at Different Wavelengths Boosts Mitochondrial Redox Metabolism and Hemoglobin Oxygenation: Lasers vs. Light-Emitting Diodes In Vivo”
by Tyrell Pruitt, Caroline Carter, Xinlong Wang, Anqi Wu and Hanli Liu
Metabolites 2022, 12(2), 103; https://doi.org/10.3390/metabo12020103
Available online: https://www.mdpi.com/2218-1989/12/2/103
3. “Systematic Evaluation of HILIC Stationary Phases for Global Metabolomics of Human Plasma”
*Editor’s Choice Paper
by Farideh Hosseinkhani, Luojiao Huang, Anne-Charlotte Dubbelman, Faisa Guled, Amy C. Harms and Thomas Hankemeier
Metabolites 2022, 12(2), 165; https://doi.org/10.3390/metabo12020165
Available online: https://www.mdpi.com/2218-1989/12/2/165
4. “Patient Stratification in Sepsis: Using Metabolomics to Detect Clinical Phenotypes, Sub-Phenotypes and Therapeutic Response”
by Humma Hussain, Kritchai Vutipongsatorn, Beatriz Jiménez and David B. Antcliffe
Metabolites 2022, 12(5), 376; https://doi.org/10.3390/metabo12050376
Available online: https://www.mdpi.com/2218-1989/12/5/376
5. “Broadband-NIRS System Identifies Epileptic Focus in a Child with Focal Cortical Dysplasia—A Case Study”
by Aikaterini Vezyroglou, Peter Hebden, Isabel De Roever, Rachel Thornton, Subhabrata Mitra, Alan Worley, Mariana Alves, Emma Dean, Judith Helen Cross and Ilias Tachtsidis
Metabolites 2022, 12(3), 260; https://doi.org/10.3390/metabo12030260
Available online: https://www.mdpi.com/2218-1989/12/3/260
6. “MALDI Mass Spectrometry Imaging Highlights Specific Metabolome and Lipidome Profiles in Salivary Gland Tumor Tissues”
by Eduardo Sommella, Emanuela Salviati, Vicky Caponigro, Manuela Grimaldi, Simona Musella, Alessia Bertamino, Luigi Cacace, Remo Palladino, Giuseppe Di Mauro, Federico Marini et al.
Metabolites 2022, 12(6), 530; https://doi.org/10.3390/metabo12060530
Available online: https://www.mdpi.com/2218-1989/12/6/530
7. “Automated Sample Preparation and Data Collection Workflow for High-Throughput In Vitro Metabolomics”
*Editor’s Choice Paper
by Julia M. Malinowska, Taina Palosaari, Jukka Sund, Donatella Carpi, Gavin R. Lloyd, Ralf J. M. Weber, Maurice Whelan and Mark R. Viant
Metabolites 2022, 12(1), 52; https://doi.org/10.3390/metabo12010052
Available online: https://www.mdpi.com/2218-1989/12/1/52
8. “Simultaneous Quantification of Steroid Hormones Using hrLC-MS in Endocrine Tissues of Male Rats and Human Samples”
by Guillermo Bordanaba-Florit, Sebastiaan van Liempd, Diana Cabrera, Félix Royo and Juan Manuel Falcón-Pérez
Metabolites 2022, 12(8), 714; https://doi.org/10.3390/metabo12080714
Available online: https://www.mdpi.com/2218-1989/12/8/714
13 April 2023
Metabolites | Hot Topic Papers Published in 2022 in the “Environmental Metabolomics” Section
1. “Mycorrhiza-Tree-Herbivore Interactions: Alterations in Poplar Metabolome and Volatilome”
by Prasath Balaji Sivaprakasam Padmanaban, Maaria Rosenkranz, Peiyuan Zhu, Moritz Kaling, Anna Schmidt, Philippe Schmitt-Kopplin, Andrea Polle and Jörg-Peter Schnitzler
Metabolites 2022, 12(2), 93; https://doi.org/10.3390/metabo12020093
Available online: https://www.mdpi.com/2218-1989/12/2/93
2. “Kinetic Modeling of Saccharomyces cerevisiae Central Carbon Metabolism: Achievements, Limitations, and Opportunities”
by David Lao-Martil, Koen J. A. Verhagen, Joep P. J. Schmitz, Bas Teusink, S. Aljoscha Wahl and Natal A. W. van Riel
Metabolites 2022, 12(1), 74; https://doi.org/10.3390/metabo12010074
Available online: https://www.mdpi.com/2218-1989/12/1/74
3. “Environmental Metabolomics Promises and Achievements in the Field of Aquatic Ecotoxicology: Viewed through the Pharmaceutical Lens”
by Thibaut Dumas, Frédérique Courant, Hélène Fenet and Elena Gomez
Metabolites 2022, 12(2), 186; https://doi.org/10.3390/metabo12020186
Available online: https://www.mdpi.com/2218-1989/12/2/186
4. “Exploring Thermal Sensitivities and Adaptations of Oxidative Phosphorylation Pathways”
by Hélène Lemieux and Pierre U. Blier
Metabolites 2022, 12(4), 360; https://doi.org/10.3390/metabo12040360
Available online: https://www.mdpi.com/2218-1989/12/4/360
5. “Spatially Mapping the Baseline and Bisphenol-A Exposed Daphnia magna Lipidome Using Desorption Electrospray Ionization—Mass Spectrometry”
by Matthew J. Smith, Ralf J. M. Weber and Mark R. Viant
Metabolites 2022, 12(1), 33; https://doi.org/10.3390/metabo12010033
Available online: https://www.mdpi.com/2218-1989/12/1/33
6. “TransDiscovery: Discovering Biotransformation from Human Microbiota by Integrating Metagenomic and Metabolomic Data”
by Donghui Yan, Liu Cao, Muqing Zhou and Hosein Mohimani
Metabolites 2022, 12(2), 119; https://doi.org/10.3390/metabo12020119
Available online: https://www.mdpi.com/2218-1989/12/2/119
7. “Early Biological Modulations Resulting from 1-Week Venlafaxine Exposure of Marine Mussels Mytilus galloprovincialis Determined by a Metabolomic Approach”
by Gaëlle Ramirez, Elena Gomez, Thibaut Dumas, David Rosain, Olivier Mathieu, Hélène Fenet and Frédérique Courant
Metabolites 2022, 12(3), 197; https://doi.org/10.3390/metabo12030197
Available online: https://www.mdpi.com/2218-1989/12/3/197
8. “Amplified Drought and Seasonal Cycle Modulate Quercus pubescens Leaf Metabolome”
by Amélie Saunier, Stéphane Greff, James D. Blande, Caroline Lecareux, Virginie Baldy, Catherine Fernandez and Elena Ormeño
Metabolites 2022, 12(4), 307; https://doi.org/10.3390/metabo12040307
Available online: https://www.mdpi.com/2218-1989/12/4/307
13 April 2023
Metabolites | Hot Topic Papers Published in 2022 in the “Animal Metabolism” Section
1. “Tea Polyphenols Protect the Mammary Gland of Dairy Cows by Enhancing Antioxidant Capacity and Regulating the TGF-β1/p38/JNK Pathway”
by Ran Xu, Mengran Zhu, Jingwen Cao and Mengyao Guo
Metabolites 2022, 12(11), 1009; https://doi.org/10.3390/metabo12111009
Available online: https://www.mdpi.com/2218-1989/12/11/1009
2. “Prenatal Supplementation in Beef Cattle and Its Effects on Plasma Metabolome of Dams and Calves”
by Fernando José Schalch Junior, Guilherme Henrique Gebim Polizel, Fernando Augusto Correia Queiroz Cançado, Arícia Christofaro Fernandes, Isabela Mortari, Pedro Ratto Lisboa Pires, Heidge Fukumasu, Miguel Henrique de Almeida Santana and Arlindo Saran Netto
Metabolites 2022, 12(4), 347; https://doi.org/10.3390/metabo12040347
Available online: https://www.mdpi.com/2218-1989/12/4/347
3. “Maternal Nutrient Restriction Disrupts Gene Expression and Metabolites Associated with Urea Cycle, Steroid Synthesis, Glucose Homeostasis, and Glucuronidation in Fetal Calf Liver”
by Susumu Muroya, Yi Zhang, Kounosuke Otomaru, Kazunaga Oshima, Ichiro Oshima, Mitsue Sano, Sanggun Roh, Koichi Ojima and Takafumi Gotoh
Metabolites 2022, 12(3), 203; https://doi.org/10.3390/metabo12030203
Available online: https://www.mdpi.com/2218-1989/12/3/203
4. “Cryoprotective Metabolites Are Sourced from Both External Diet and Internal Macromolecular Reserves during Metabolic Reprogramming for Freeze Tolerance in Drosophilid Fly, Chymomyza costata”
by Martin Moos, Jaroslava Korbelová, Tomáš Štětina, Stanislav Opekar, Petr Šimek, Robert Grgac and Vladimír Koštál
Metabolites 2022, 12(2), 163; https://doi.org/10.3390/metabo12020163
Available online: https://www.mdpi.com/2218-1989/12/2/163
5. “Qualitative and Quantitative Effects of Fatty Acids Involved in Heart Diseases”
by Hidenori Moriyama, Jin Endo, Hidehiko Ikura, Hiroki Kitakata, Mizuki Momoi, Yoshiki Shinya, Seien Ko, Genki Ichihara, Takahiro Hiraide, Kohsuke Shirakawa et al.
Metabolites 2022, 12(3), 210; https://doi.org/10.3390/metabo12030210
Available online: https://www.mdpi.com/2218-1989/12/3/210
6. “Production of Hydroxy Fatty Acids, Precursors of γ-Hexalactone, Contributes to the Characteristic Sweet Aroma of Beef”
by Shuji Ueda, Mana Hosoda, Kumi Kasamatsu, Masahiro Horiuchi, Rio Nakabayashi, Bubwoong Kang, Masakazu Shinohara, Hiroki Nakanishi, Takayo Ohto-Nakanishi, Minoru Yamanoue and Yasuhito Shirai
Metabolites 2022, 12(4), 332; https://doi.org/10.3390/metabo12040332
Available online: https://www.mdpi.com/2218-1989/12/4/332
7. “Comparative Metabolomics of Small Molecules Specifically Expressed in the Dorsal or Ventral Marginal Zones in Vertebrate Gastrula”
by Yukako Suzuki, Ryosuke Hayasaka, Masako Hasebe, Satsuki Ikeda, Tomoyoshi Soga, Masaru Tomita, Akiyoshi Hirayama and Hiroki Kuroda
Metabolites 2022, 12(6), 566; https://doi.org/10.3390/metabo12060566
Available online: https://www.mdpi.com/2218-1989/12/6/566
8. “Relationships between Milk and Blood Biochemical Parameters and Metabolic Status in Dairy Cows during Lactation”
by Biljana Andjelić, Radojica Djoković, Marko Cincović, Snežana Bogosavljević-Bošković, Milun Petrović, Jelena Mladenović and Aleksandar Čukić
Metabolites 2022, 12(8), 733; https://doi.org/10.3390/metabo12080733
Available online: https://www.mdpi.com/2218-1989/12/8/733