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Citations	Article
695	A Historical Overview of Natural Products in Drug Discovery by Daniel A. Dias, Sylvia Urban and Ute Roessner
153	Software Tools and Approaches for Compound Identification of LC-MS/MS Data in Metabolomics by Ivana Blaženović, Tobias Kind, Jian Ji and Oliver Fiehn
150	Carbonic Anhydrase Inhibition and the Management of Hypoxic Tumors by Claudiu T. Supuran
135	A Guideline to Univariate Statistical Analysis for LC/MS-Based Untargeted Metabolomics-Derived Data by Maria Vinaixa, Sara Samino, Isabel Saez, Jordi Duran, Joan J. Guinovart and Oscar Yanes
130	Breath Analysis in Disease Diagnosis: Methodological Considerations and Applications by Célia Lourenço and Claire Turner
125	NMR Spectroscopy for Metabolomics Research by Abdul-Hamid Emwas, Raja Roy, Ryan T. McKay, Leonardo Tenori, Edoardo Saccenti, G. A. Nagana Gowda, Daniel Raftery, Fatimah Alahmari, Lukasz Jaremko, Mariusz Jaremko and David S. Wishart
121	Breath Analysis as a Potential and Non-Invasive Frontier in Disease Diagnosis: An Overview by Jorge Pereira, Priscilla Porto-Figueira, Carina Cavaco, Khushman Taunk, Srikanth Rapole, Rahul Dhakne, Hampapathalu Nagarajaram and José S. Câmara
115	A Review of Applications of Metabolomics in Cancer by Richard D. Beger
115	Advances in Electronic-Nose Technologies for the Detection of Volatile Biomarker Metabolites in the Human Breath by Alphus D. Wilson
111	Mass Spectrometry Based Lipidomics: An Overview of Technological Platforms by Harald C. Köfeler, Alexander Fauland, Gerald N. Rechberger and Martin Trötzmüller

Citations	Article
6	Glucagon-Like Peptide-1 Receptor Agonists for Treatment of Nonalcoholic Fatty Liver Disease and Nonalcoholic Steatohepatitis: An Updated Meta-Analysis of Randomized Controlled Trials by Alessandro Mantovani, Graziana Petracca, Giorgia Beatrice, Alessandro Csermely, Amedeo Lonardo and Giovanni Targher
4	Sodium-Glucose Cotransporter-2 Inhibitors for Treatment of Nonalcoholic Fatty Liver Disease: A Meta-Analysis of Randomized Controlled Trials by Alessandro Mantovani, Graziana Petracca, Alessandro Csermely, Giorgia Beatrice and Giovanni Targher
4	Biostimulants for Plant Growth and Mitigation of Abiotic Stresses: A Metabolomics Perspective by Lerato Nephali, Lizelle A. Piater, Ian A. Dubery, Veronica Patterson, Johan Huyser, Karl Burgess and Fidele Tugizimana
3	Prediction of Autoimmune Diseases by Targeted Metabolomic Assay of Urinary Organic Acids by Dimitris Tsoukalas, Vassileios Fragoulakis, Evangelos Papakonstantinou, Maria Antonaki, Athanassios Vozikis, Aristidis Tsatsakis, Ana Maria Buga, Mihaela Mitroi and Daniela Calina
3	Metabolic Signatures of the Exposome—Quantifying the Impact of Exposure to Environmental Chemicals on Human Health by Matej Orešič, Aidan McGlinchey, Craig E. Wheelock and Tuulia Hyötyläinen
3	Sensing and Signaling of Methionine Metabolism by Linda Lauinger and Peter Kaiser
3	Gut Microbiota Dysbiosis Is Associated with Elevated Bile Acids in Parkinson’s Disease by Peipei Li, Bryan A. Killinger, Elizabeth Ensink, Ian Beddows, Ali Yilmaz, Noah Lubben, Jared Lamp, Meghan Schilthuis, Irving E. Vega, Randy Woltjer, J. Andrew Pospisilik, Patrik Brundin, Lena Brundin, Stewart F. Graham and Viviane Labrie
2	Integration of Lipidomics and Transcriptomics Reveals Reprogramming of the Lipid Metabolism and Composition in Clear Cell Renal Cell Carcinoma by Giuseppe Lucarelli, Matteo Ferro, Davide Loizzo, Cristina Bianchi, Daniela Terracciano, Francesco Cantiello, Lauren N. Bell, Stefano Battaglia, Camillo Porta, Angela Gernone, Roberto A. Perego, Eugenio Maiorano, Ottavio de Cobelli, Giuseppe Castellano, Leonardo Vincenti, Pasquale Ditonno and Michele Battaglia
2	Developmental Programming and Glucolipotoxicity: Insights on Beta Cell Inflammation and Diabetes by Marlon E. Cerf
2	Anti-Adipogenic Effect of Theabrownin Is Mediated by Bile Acid Alternative Synthesis via Gut Microbiota Remodeling by Junliang Kuang, Xiaojiao Zheng, Fengjie Huang, Shouli Wang, Mengci Li, Mingliang Zhao, Chao Sang, Kun Ge, Yitao Li, Jiufeng Li, Cynthia Rajani, Xiaohui Ma, Shuiping Zhou, Aihua Zhao and Wei Jia

Citations	Article
79	MetaboAnalystR 3.0: Toward an Optimized Workflow for Global Metabolomics by Zhiqiang Pang, Jasmine Chong, Shuzhao Li and Jianguo Xia
17	Machine Learning Applications for Mass Spectrometry-Based Metabolomics by Ulf W. Liebal, An N. T. Phan, Malvika Sudhakar, Karthik Raman and Lars M. Blank
13	Carbonic Anhydrase Inhibitors Targeting Metabolism and Tumor Microenvironment by Andrea Angeli, Fabrizio Carta, Alessio Nocentini, Jean-Yves Winum, Raivis Zalubovskis, Atilla Akdemir, Valentina Onnis, Wagdy M. Eldehna, Clemente Capasso, Giuseppina De Simone, Simona Maria Monti, Simone Carradori, William A. Donald, Shoukat Dedhar and Claudiu T. Supuran
12	The Pentose Phosphate Pathway Dynamics in Cancer and Its Dependency on Intracellular pH by Khalid O. Alfarouk, Samrein B. M. Ahmed, Robert L. Elliott, Amanda Benoit, Saad S. Alqahtani, Muntaser E. Ibrahim, Adil H. H. Bashir, Sari T. S. Alhoufie, Gamal O. Elhassan, Christian C. Wales, Laurent H. Schwartz, Heyam S. Ali, Ahmed Ahmed, Patrick F. Forde, Jesus Devesa, Rosa A. Cardone, Stefano Fais, Salvador Harguindey and Stephan J. Reshkin
11	Dyslipidemia: A Trigger for Coronary Heart Disease in Romanian Patients with Diabetes by Mihnea-Alexandru Găman, Matei-Alexandru Cozma, Elena-Codruța Dobrică, Nicolae Bacalbașa, Ovidiu Gabriel Bratu and Camelia Cristina Diaconu
10	The Bovine Metabolome by Aidin Foroutan, Carolyn Fitzsimmons, Rupasri Mandal, Hamed Piri-Moghadam, Jiamin Zheng, AnChi Guo, Carin Li, Le Luo Guan and David S. Wishart
9	Metabolomics and Multi-Omics Integration: A Survey of Computational Methods and Resources by Tara Eicher, Garrett Kinnebrew, Andrew Patt, Kyle Spencer, Kevin Ying, Qin Ma, Raghu Machiraju and Ewy A. Mathé
8	Metabolite Changes during Postharvest Storage: Effects on Fruit Quality Traits by Delphine M. Pott, José G. Vallarino and Sonia Osorio
7	Current Status of Metabolomic Biomarker Discovery: Impact of Study Design and Demographic Characteristics by Vladimir Tolstikov, A. James Moser, Rangaprasad Sarangarajan, Niven R. Narain and Michael A. Kiebish
7	Metabolomic Biomarkers for Detection, Prognosis and Identifying Recurrence in Endometrial Cancer by Kelechi Njoku, Caroline J.J Sutton, Anthony D. Whetton and Emma J. Crosbie

Citations	Article
125	NMR Spectroscopy for Metabolomics Research by Abdul-Hamid Emwas, Raja Roy, Ryan T. McKay, Leonardo Tenori, Edoardo Saccenti, G. A. Nagana Gowda, Daniel Raftery, Fatimah Alahmari, Lukasz Jaremko, Mariusz Jaremko and David S. Wishart
79	MetaboAnalystR 3.0: Toward an Optimized Workflow for Global Metabolomics by Zhiqiang Pang, Jasmine Chong, Shuzhao Li and Jianguo Xia
59	A Comprehensive Review on Medicinal Plants as Antimicrobial Therapeutics: Potential Avenues of Biocompatible Drug Discovery by Uttpal Anand, Nadia Jacobo-Herrera, Ammar Altemimi and Naoufal Lakhssassi
46	MolNetEnhancer: Enhanced Molecular Networks by Integrating Metabolome Mining and Annotation Tools by Madeleine Ernst, Kyo Bin Kang, Andrés Mauricio Caraballo-Rodríguez, Louis-Felix Nothias, Joe Wandy, Christopher Chen, Mingxun Wang, Simon Rogers, Marnix H. Medema, Pieter C. Dorrestein and Justin J.J. van der Hooft
32	Translational Metabolomics: Current Challenges and Future Opportunities by Farhana R. Pinu, Seyed Ali Goldansaz and Jacob Jaine
32	Pre-Analytical Factors that Affect Metabolite Stability in Human Urine, Plasma, and Serum: A Review by Victoria L. Stevens, Elise Hoover, Ying Wang and Krista A. Zanetti
25	Metabolomics-Based Studies Assessing Exercise-Induced Alterations of the Human Metabolome: A Systematic Review by Camila A. Sakaguchi, David C. Nieman, Etore F. Signini, Raphael M. Abreu and Aparecida M. Catai
22	From Samples to Insights into Metabolism: Uncovering Biologically Relevant Information in LC-HRMS Metabolomics Data by Julijana Ivanisevic and Elizabeth J. Want
20	Effects of Long-Term Storage at −80 °C on the Human Plasma Metabolome by Antje Wagner-Golbs, Sebastian Neuber, Beate Kamlage, Nicole Christiansen, Bianca Bethan, Ulrike Rennefahrt, Philipp Schatz and Lars Lind
20	The metaRbolomics Toolbox in Bioconductor and beyond by Jan Stanstrup, Corey D. Broeckling, Rick Helmus, Nils Hoffmann, Ewy Mathé, Thomas Naake, Luca Nicolotti, Kristian Peters, Johannes Rainer, Reza M. Salek, Tobias Schulze, Emma L. Schymanski, Michael A. Stravs, Etienne A. Thévenot, Hendrik Treutler, Ralf J. M. Weber, Egon Willighagen, Michael Witting and Steffen Neumann

Citations	Article
153	Software Tools and Approaches for Compound Identification of LC-MS/MS Data in Metabolomics by Ivana Blaženović, Tobias Kind, Jian Ji and Oliver Fiehn
125	NMR Spectroscopy for Metabolomics Research by Abdul-Hamid Emwas, Raja Roy, Ryan T. McKay, Leonardo Tenori, Edoardo Saccenti, G. A. Nagana Gowda, Daniel Raftery, Fatimah Alahmari, Lukasz Jaremko, Mariusz Jaremko and David S. Wishart
108	Systems Biology and Multi-Omics Integration: Viewpoints from the Metabolomics Research Community by Farhana R. Pinu, David J. Beale, Amy M. Paten, Konstantinos Kouremenos, Sanjay Swarup, Horst J. Schirra and David Wishart
107	MetaboAnalystR 2.0: From Raw Spectra to Biological Insights by Jasmine Chong, Mai Yamamoto and Jianguo Xia
79	MetaboAnalystR 3.0: Toward an Optimized Workflow for Global Metabolomics by Zhiqiang Pang, Jasmine Chong, Shuzhao Li and Jianguo Xia
64	CFM-ID 3.0: Significantly Improved ESI-MS/MS Prediction and Compound Identification by Yannick Djoumbou-Feunang, Allison Pon, Naama Karu, Jiamin Zheng, Carin Li, David Arndt, Maheswor Gautam, Felicity Allen and David S. Wishart
59	A Comprehensive Review on Medicinal Plants as Antimicrobial Therapeutics: Potential Avenues of Biocompatible Drug Discovery by Uttpal Anand, Nadia Jacobo-Herrera, Ammar Altemimi and Naoufal Lakhssassi
46	MolNetEnhancer: Enhanced Molecular Networks by Integrating Metabolome Mining and Annotation Tools by Madeleine Ernst, Kyo Bin Kang, Andrés Mauricio Caraballo-Rodríguez, Louis-Felix Nothias, Joe Wandy, Christopher Chen, Mingxun Wang, Simon Rogers, Marnix H. Medema, Pieter C. Dorrestein and Justin J.J. van der Hooft
35	Critical Review of Volatile Organic Compound Analysis in Breath and In Vitro Cell Culture for Detection of Lung Cancer by Zhunan Jia, Abhijeet Patra, Viknish Krishnan Kutty and Thirumalai Venkatesan
32	Translational Metabolomics: Current Challenges and Future Opportunities by Farhana R. Pinu, Seyed Ali Goldansaz and Jacob Jaine

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9730	New Strategies for the Treatment of Phenylketonuria (PKU) by Pietro Strisciuglio and Daniela Concolino
9321	Unraveling Biochemical Pathways Affected by Mitochondrial Dysfunctions Using Metabolomic Approaches by Stéphane Demine, Nagabushana Reddy, Patricia Renard, Martine Raes and Thierry Arnould
8461	Comprehensive Circulatory Metabolomics in ME/CFS Reveals Disrupted Metabolism of Acyl Lipids and Steroids by Arnaud Germain, Dinesh K. Barupal, Susan M. Levine and Maureen R. Hanson
8390	A Guideline to Univariate Statistical Analysis for LC/MS-Based Untargeted Metabolomics-Derived Data by Maria Vinaixa, Sara Samino, Isabel Saez, Jordi Duran, Joan J. Guinovart and Oscar Yanes
8370	Alkylation or Silylation for Analysis of Amino and Non-Amino Organic Acids by GC-MS? by Silas G. Villas-Bôas, Kathleen F. Smart, Subathira Sivakumaran and Geoffrey A. Lane
8266	A Review of Applications of Metabolomics in Cancer by Richard D. Beger
7947	The Complex Role of Branched Chain Amino Acids in Diabetes and Cancer by Thomas M. O'Connell
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2130	Pathway Tools Visualization of Organism-Scale Metabolic Networks by Suzanne Paley, Richard Billington, James Herson, Markus Krummenacker and Peter D. Karp
1972	Gut Microbiota Dysbiosis Is Associated with Elevated Bile Acids in Parkinson’s Disease by Peipei Li, Bryan A. Killinger, Elizabeth Ensink, Ian Beddows, Ali Yilmaz, Noah Lubben, Jared Lamp, Meghan Schilthuis, Irving E. Vega, Randy Woltjer, J. Andrew Pospisilik, Patrik Brundin, Lena Brundin, Stewart F. Graham and Viviane Labrie
1951	Prediction of Autoimmune Diseases by Targeted Metabolomic Assay of Urinary Organic Acids by Dimitris Tsoukalas, Vassileios Fragoulakis, Evangelos Papakonstantinou, Maria Antonaki, Athanassios Vozikis, Aristidis Tsatsakis, Ana Maria Buga, Mihaela Mitroi and Daniela Calina
1938	Single-Step Extraction Coupled with Targeted HILIC-MS/MS Approach for Comprehensive Analysis of Human Plasma Lipidome and Polar Metabolome by Jessica Medina, Vera van der Velpen, Tony Teav, Yann Guitton, Hector Gallart-Ayala and Julijana Ivanisevic
1870	Linking Gut Microbiome and Lipid Metabolism: Moving beyond Associations by Santosh Lamichhane, Partho Sen, Marina Amaral Alves, Henrique C. Ribeiro, Peppi Raunioniemi, Tuulia Hyötyläinen and Matej Orešič
1400	*Elevated Trehalose Levels in C. elegans daf-2* Mutants Increase Stress Resistance, Not Lifespan** by Madina Rasulova, Aleksandra Zečić, Jose Manuel Monje Moreno, Lieselot Vandemeulebroucke, Ineke Dhondt and Bart P. Braeckman
1385	Metabolic Predictors of Equine Performance in Endurance Racing by Anna Halama, Joao M. Oliveira, Silvio A. Filho, Muhammad Qasim, Iman W. Achkar, Sarah Johnson, Karsten Suhre and Tatiana Vinardell
1380	Cholesterol Activates Cyclic AMP Signaling in Metaplastic Acinar Cells by Francesca Grisan, Martina Spacci, Carlotta Paoli, Andrea Costamagna, Marco Fantuz, Miriam Martini, Konstantinos Lefkimmiatis and Alessandro Carrer
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2644	Machine Learning Applications for Mass Spectrometry-Based Metabolomics by Ulf W. Liebal, An N. T. Phan, Malvika Sudhakar, Karthik Raman and Lars M. Blank
2538	Comprehensive Meta-Analysis of COVID-19 Global Metabolomics Datasets by Zhiqiang Pang, Guangyan Zhou, Jasmine Chong and Jianguo Xia
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1972	Gut Microbiota Dysbiosis Is Associated with Elevated Bile Acids in Parkinson’s Disease by Peipei Li, Bryan A. Killinger, Elizabeth Ensink, Ian Beddows, Ali Yilmaz, Noah Lubben, Jared Lamp, Meghan Schilthuis, Irving E. Vega, Randy Woltjer, J. Andrew Pospisilik, Patrik Brundin, Lena Brundin, Stewart F. Graham and Viviane Labrie
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1938	Single-Step Extraction Coupled with Targeted HILIC-MS/MS Approach for Comprehensive Analysis of Human Plasma Lipidome and Polar Metabolome by Jessica Medina, Vera van der Velpen, Tony Teav, Yann Guitton, Hector Gallart-Ayala and Julijana Ivanisevic
1892	A High-Throughput Method for the Comprehensive Analysis of Terpenes and Terpenoids in Medicinal Cannabis Biomass by Christian Krill, Simone Rochfort and German Spangenberg
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5566	NMR Spectroscopy for Metabolomics Research by Abdul-Hamid Emwas, Raja Roy, Ryan T. McKay, Leonardo Tenori, Edoardo Saccenti, G. A. Nagana Gowda, Daniel Raftery, Fatimah Alahmari, Lukasz Jaremko, Mariusz Jaremko and David S. Wishart
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1655	Comprehensive Meta-Analysis of COVID-19 Global Metabolomics Datasets by Zhiqiang Pang, Guangyan Zhou, Jasmine Chong and Jianguo Xia
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