Special Issues

Metabolites publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue polices and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Metabolic Responses of Plants to Abiotic Stress
edited by and
submission deadline 15 Jul 2024 | 8 articles | Viewed by 10261 | Submission Open
Keywords: climate change; abiotic stress; carbohydrates; nitrogen metabolism; metabolomics; ROS and antioxidants; memory effects; secondary metabolites; epigenetic regulations
(This special issue belongs to the Section Plant Metabolism)
Metabolomics in Disease Mechanisms and Drug Targets
edited by
submission deadline 15 Jul 2024 | 1 articles | Viewed by 2430 | Submission Open
Keywords: metabolomics; disease mechanism; drug target; biomarker; disease prediction
(This special issue belongs to the Section Metabolomic Profiling Technology)
Exploring and Expanding Horizons in Secondary Metabolites: Biosynthesis, Identification, Regulation and Biological Activity
edited by , and Claúdia Quintino Da Rocha
submission deadline 15 Jul 2024 | 1 articles | Viewed by 1488 | Submission Open
Keywords: secondary metabolites; biosynthesis; regulation; identification; plants; microorganisms; marine organisms; animals; bioactivity; drug discovery; natural products
(This special issue belongs to the Section Pharmacology and Drug Metabolism)
The Role of Metabolites in Translational and Clinical Pharmacology
edited by , Xinning Yang, Eva Berglund and Rheem A. Totah
submission deadline 15 Jul 2024 | Viewed by 933 | Submission Open
Keywords: metabolism; transport; ADME; PK; DDI; special populations; endogenous metabolite biomarker; PBPK and PK/PD modeling
(This special issue belongs to the Section Pharmacology and Drug Metabolism)
Inflammation and Oxidative Stress in Age-Related Metabolic Changes and Disorders
edited by , and Grzegorz Dziubanek
submission deadline 15 Jul 2024 | Viewed by 372 | Submission Open
Keywords: nutritional attitudes and behaviors; bioconcentration factor; health risk assessment; dietary exposure; farm-fresh foods; medicinal plants; gut microbiota; dietary supplements; trace elements— Zn; Cu; heavy metals
(This special issue belongs to the Section Nutrition and Metabolism)
Glucose Metabolism in Pregnancy
edited by Moen Gunn-Helen
submission deadline 20 Jul 2024 | 1 articles | Viewed by 1482 | Submission Open
Keywords: glucose metabolism; gestational diabetes; pregnancy; diabetes; glucose
(This special issue belongs to the Section Endocrinology and Clinical Metabolic Research)
The Emerging Role of Metabolomics in Epidemiological Studies of Atherosclerosis and Cardiovascular Disease submission deadline 20 Jul 2024 | Viewed by 579 | Submission Open
Keywords: cardiovascular disease; epidemiology; metabolic disease; metabolomics; multi-omics
(This special issue belongs to the Section Advances in Metabolomics)
The Role of Hepatic Insulin Clearance in Obesity and Type 2 Diabetes
edited by and Richard N. Bergman
submission deadline 25 Jul 2024 | Viewed by 234 | Submission Open
Keywords: insulin clearance; insulin resistance; type 2 diabetes; obesity; hyperinsulinemia
(This special issue belongs to the Section Endocrinology and Clinical Metabolic Research)
Natural Metabolites on Gut Microbiome Modulation
edited by
submission deadline 30 Jul 2024 | 2 articles | Viewed by 8128 | Submission Open
Keywords: natural metabolites; gut microbiome; gut microbiome modulator; human health; human diseases
(This special issue belongs to the Section Advances in Metabolomics)
LC-MS Method Development and Metabolomics Data Analysis
edited by Chaevien S. Clendinen and Lisa Bramer
submission deadline 30 Jul 2024 | Viewed by 310 | Submission Open
Keywords: LC– MS; data visualization; mass spectrometry; NMR; chromatography; metabolomics; lipidomics
(This special issue belongs to the Section Bioinformatics and Data Analysis)
Mass Spectrometry Imaging: Theory, Methods and Applications in Biochemical and Pharmaceutical Research
edited by
submission deadline 31 Jul 2024 | 4 articles | Viewed by 4723 | Submission Open
Keywords: in situ ionization; MS imaging data processing; multimodular imaging; spatial multi-omics; clinical diagnosis; drug research and development; cancer metabolism
(This special issue belongs to the Section Metabolomic Profiling Technology)
Unlocking the Mysteries of Muscle Metabolism in the Animal Sciences submission deadline 31 Jul 2024 | 4 articles | Viewed by 3424 | Submission Open
Keywords: muscle; amino acid metabolism; energy metabolism; metabolites; protein; growth
(This special issue belongs to the Section Animal Metabolism)
Advances in Salivary Metabolomics for Oral and Systemic Diseases
edited by
submission deadline 31 Jul 2024 | 2 articles | Viewed by 2364 | Submission Open
Keywords: metabolomics; salivary metabolites; oral diseases; oral cancer; periodontal diseases; oral microbiome; systemic diseases
(This special issue belongs to the Section Endocrinology and Clinical Metabolic Research)
Metabolomic Profiling in Equine Medicine and Reproduction
edited by and Fulvio Laus
submission deadline 31 Jul 2024 | 1 articles | Viewed by 1886 | Submission Open
Keywords: metabolomic analysis; horse; donkey; mule; equine medicine; equine reproduction; biomarker; metabolite; metabolome
(This special issue belongs to the Section Animal Metabolism)
Recent Advances in Radiation Research
edited by
submission deadline 31 Jul 2024 | 1 articles | Viewed by 1734 | Submission Open
Keywords: ionizing radiation; radiotherapy; space radiation; radiation protection; metabolomics; lipidomics; multi-omics
(This special issue belongs to the Section Advances in Metabolomics)
Drug Metabolism and New Drug Development for Cancers submission deadline 31 Jul 2024 | 1 articles | Viewed by 1493 | Submission Open
Keywords: cancer; new drug development; metabolites; secondary plant metabolites; drug delivery; nanoformulation; anticancer treatment
(This special issue belongs to the Section Pharmacology and Drug Metabolism)
Metabolic Biomarkers and Nutrition in Degenerative Conditions and Gastrointestinal Cancer Surgery
edited by , and Maximos Frountzas
submission deadline 31 Jul 2024 | 1 articles | Viewed by 1490 | Submission Open
Keywords: biomarkers; nutrition; metabolism; metabolomics; degenerative disease; Parkinson’ s disease; Alzheimer’ s disease; cardiovascular disease; gastrointestinal cancer surgery
(This special issue belongs to the Section Nutrition and Metabolism)
Targeting Microbiota and Metabolites for Prevention and Treatment of Human Diseases
edited by and
submission deadline 31 Jul 2024 | 2 articles | Viewed by 1142 | Submission Open
Keywords: microbiota; metabolites; metabolic diseases; cancer; cardiovascular diseases; liver diseases
(This special issue belongs to the Section Endocrinology and Clinical Metabolic Research)
Changing Diagnosis, Treatment and Monitoring of Rare Genetic Disorders in the -Omics Era
edited by Adviye Ayper Tolun and
submission deadline 31 Jul 2024 | Viewed by 242 | Submission Open
Keywords: inborn errors of metabolism; rare genetic diseases; clinical metabolomics; multiomics; biomarker discovery
(This special issue belongs to the Section Integrative Metabolomics)
New Perspectives in the Diagnosis and Treatment of Type 2 Diabetes and Its Complications
edited by Péter Kempler and Zsuzsanna Putz
submission deadline 31 Jul 2024 | Viewed by 227 | Submission Open
Keywords: type 2 diabetes mellitus; microvascular complications; diabetic neuropathy; diabetic nephropathy; diabetic retinopathy; glucose database analysis
(This special issue belongs to the Section Nutrition and Metabolism)
Brain Metabolism Models and Research
edited by Jennifer M. Lynch and
submission deadline 31 Jul 2024 | Viewed by 158 | Submission Open
Keywords: brain mitochondria; brain oxidative stress; neuroinflammation; brain insulin signaling; brain lipid metabolism; brain aging; neurodegenerative diseases; neurodevelopmental disorders; microbiome and brain
(This special issue belongs to the Section Nutrition and Metabolism)
Metabolites and Thyroid
edited by Carolina Castro Porto Silva Janovsky and Caroline Serrano-Nascimento
submission deadline 1 Aug 2024 | Viewed by 259 | Submission Open
Keywords: metabolomics; hypothyroidism; hyperthyroidism; thyroid cancer; thyroid function; endocrine disruptors; lipidomics; proteomics
(This special issue belongs to the Section Nutrition and Metabolism)
New Insights on the Role of Lipid Metabolism in the Development of Cardiac Dysfunction
edited by
submission deadline 1 Aug 2024 | Viewed by 246 | Submission Open
(This special issue belongs to the Section Lipid Metabolism)
Metabolomics-Based Biomarkers for Nutrition and Health
edited by Cheng Zheng and
submission deadline 2 Aug 2024 | 1 articles | Viewed by 1157 | Submission Open
Keywords: biomarker; metabolomics; nutritional epidemiology; disease diagnostics and prevention; risk prediction
(This special issue belongs to the Section Nutrition and Metabolism)
Sports: Nutrition and Metabolism in Relation to Athletes’ Health and Performance
edited by
submission deadline 5 Aug 2024 | 4 articles | Viewed by 4940 | Submission Open
Keywords: sports; physiology; metabolism; nutrition; rapid weight loss; body mass maintenance; performance; energy system contributions
(This special issue belongs to the Section Nutrition and Metabolism)
Effects of Biotic/Abiotic Stress on Plant Metabolism submission deadline 13 Aug 2024 | 8 articles | Viewed by 11999 | Submission Open
Keywords: biotic and abiotic stresses; plant primary and secondary metabolites; plant stress response; plant metabolomics; biologically active plant metabolites; phytochemical composition of plant metabolites; biotechnological production of plant metabolites; biostimulants for plant stress mitigation
(This special issue belongs to the Section Plant Metabolism)
Lifestyle Interventions: A Challenging Therapeutic Strategy for Metabolic Syndrome 2nd Edition submission deadline 15 Aug 2024 | 1 articles | Viewed by 2018 | Submission Open
Keywords: diabetes; metabolic syndrome; insulin resistance; obesity
(This special issue belongs to the Section Endocrinology and Clinical Metabolic Research)
Nutrition and Metabolism in Human Diseases 2nd Edition
edited by
submission deadline 15 Aug 2024 | 1 articles | Viewed by 1258 | Submission Open
Keywords: nutrition; metabolism; nutrient; metabolite; disease
(This special issue belongs to the Section Nutrition and Metabolism)
Honorary Special Issue Dedicated to Prof. Giovanni Targher–the Metabolic Fatty Liver Syndromes: MASLD/MAFLD/NAFLD submission deadline 15 Aug 2024 | 1 articles | Viewed by 845 | Submission Open
Keywords: nonalcoholic fatty liver disease (NAFLD); metabolic associated fatty liver disease (MAFLD); nonalcoholic steatohepatitis (NASH); metabolic dysfunction-associated steatotic liver disease (MASLD); fatty liver
(This special issue belongs to the Section Endocrinology and Clinical Metabolic Research)
Reactive Oxygen Species and Energy Metabolic Alterations in Health and Disease submission deadline 15 Aug 2024 | Viewed by 194 | Submission Open
Keywords: cancer; ROS; glycolysis; mitochondria; autophagy; antioxidant system; glutathione; oxidative phosphorylation
(This special issue belongs to the Section Cell Metabolism)
Effect of Exogenous or Endogenous Regulatory Factors on Metabolic Responses of Plants to Biotic/Abiotic Stress
edited by
submission deadline 18 Aug 2024 | 1 articles | Viewed by 1298 | Submission Open
Keywords: biotic and abiotic stresses; biochemistry and biosynthesis of secondary metabolites; stress response and metabolic regulation; plant metabolomics under stress; lipid metabolism; root exudates composition under stress; exogenous or endogenous regulatory factors; ROS and antioxidants; plant regulation signaling pathways; plant growth promotion and metabolic mechanism
(This special issue belongs to the Section Plant Metabolism)
Metabolomic Advances in Promoting Exercise-Induced Metabolic Changes
edited by and Mara Patrıcia Traina Chacon-Mikahi
submission deadline 20 Aug 2024 | 5 articles | Viewed by 7956 | Submission Open
Keywords: metabolome; metabolites; exercise; physical activity; metabolic signatures
(This special issue belongs to the Section Advances in Metabolomics)
Cellular Metabolism in Neurological Disorders submission deadline 20 Aug 2024 | 3 articles | Viewed by 7557 | Submission Open
Keywords: metabolism  ; neurodegeneration  ; mitochondria  ; glycogen; therapeutic targets; neurons; glia
(This special issue belongs to the Section Cell Metabolism)
Neuronutrition: Metabolomic Insights and Perspectives
edited by and Rocío Campos Vega
submission deadline 30 Aug 2024 | Viewed by 1989 | Submission Open
Keywords: neuronutrition; neurological disorders; nutrition; functional foods; nutraceutical; nutrition physiology; nutriomics
(This special issue belongs to the Section Nutrition and Metabolism)
Metabolism in Aquatic Products
edited by Kuohsun Chiu
submission deadline 30 Aug 2024 | 1 articles | Viewed by 1836 | Submission Open
Keywords: metabolism; physiology; marine biology; fish; shellfish; nutrition; seafood; aquatic organism
(This special issue belongs to the Section Animal Metabolism)
Animal Nutritional Metabolism and Toxicosis Disease
edited by
submission deadline 30 Aug 2024 | 2 articles | Viewed by 1065 | Submission Open
Keywords: high-fat food; mammals; fish; metabolic blocks; toxosis; treatment of disease
(This special issue belongs to the Section Animal Metabolism)
Proteomics and Metabolomics in Veterinary and Animal Health submission deadline 30 Aug 2024 | Viewed by 164 | Submission Open
Keywords: metabolomics; proteomics; bioinformatics; omics data integration; mass spectrometry; veterinary medicine; animal health; biomarker discovery; metabolic pathways; molecular interactions
(This special issue belongs to the Section Integrative Metabolomics)
Dietary Strategies for Metabolic Syndrome submission deadline 31 Aug 2024 | 5 articles | Viewed by 9016 | Submission Open
Keywords: metabolic syndrome; dietary strategies; mediterranean Diet; nutraceuticals; noncommunicable diseases; microbiota
(This special issue belongs to the Section Food Metabolomics)
Molecular Mechanism of Lipid Metabolism in Periparturient Animal Liver
edited by , , Chuang Xu, and Lamei Wang
submission deadline 31 Aug 2024 | 4 articles | Viewed by 7430 | Submission Open
Keywords: periparturient animal; negative energy balance; fat mobilization; lipid metabolism; fatty liver
(This special issue belongs to the Section Animal Metabolism)
Trace Metal Element Metabolism in Biological Systems
edited by and
submission deadline 31 Aug 2024 | 4 articles | Viewed by 6985 | Submission Open
Keywords: trace metal elements; homeostasis mechanism; protein misfolding; protein modification; autophagy; human disease; plant disease; epidemic disease
(This special issue belongs to the Section Nutrition and Metabolism)
Novel Metabolomics and Techniques for Metabolic Disorders in Intestinal Microbiota
edited by and
submission deadline 31 Aug 2024 | 3 articles | Viewed by 6293 | Submission Open
Keywords: intestinal microbiota; metabolomics; LC-MS; GC-MS; virulence factor; microbial and host co-metabolite; metabolic reprogramming; metabolic disorders
(This special issue belongs to the Section Microbiology and Ecological Metabolomics)
Association between Natural Products and the Metabolism in Humans
edited by and
submission deadline 31 Aug 2024 | 2 articles | Viewed by 3524 | Submission Open
Keywords: natural products; molecular mechanisms; metabolic transformation; cell metabolism; ADME; metabolomics; bioactivity
(This special issue belongs to the Section Cell Metabolism)
Editorial Board Members’ Collection Series: Metabolic Pathway Mapping and Enrichment
edited by
submission deadline 31 Aug 2024 | 1 articles | Viewed by 3434 | Submission Open
Keywords: metabolite; metabolomics; systems biology; data analysis; bioinformatics; metabolite pathway mapping; metabolite pathway enrichment analysis (MPEA)
(This special issue belongs to the Section Bioinformatics and Data Analysis)
Obesity and Metabolic Dysfunction: Disease Development and Breaking the Cycle
edited by Paulo Cezar de Freitas Mathias, Lucas Paulo Jacinto Saavedra and
submission deadline 31 Aug 2024 | 2 articles | Viewed by 3298 | Submission Open
Keywords: obesity; diabetes; DOHaD; metabolic programming; treatment; intervention; cardiovascular disease; metabolic syndrome
(This special issue belongs to the Section Endocrinology and Clinical Metabolic Research)
Exercise Physiology and Cardiovascular Metabolism submission deadline 31 Aug 2024 | 1 articles | Viewed by 1730 | Submission Open
Keywords: non-communicable diseases; vascular aging; exercise intervention; hypoxic conditions; cardiometabolic biomarkers; arterial stiffness; endothelial dysfunction; sports performances
(This special issue belongs to the Section Endocrinology and Clinical Metabolic Research)
Environmental Factors Affecting Fish Metabolism submission deadline 31 Aug 2024 | 1 articles | Viewed by 1630 | Submission Open
Keywords: bioaccumulation; biotoxins; drugs and metabolites; molecular biology; nanocontaminants; oxidative stress; physiological condition; OMICs
(This special issue belongs to the Section Animal Metabolism)
Bioactive Compounds in Animal Nutrition Resources and Animal By-Products
edited by and Mario Cuchillo Hilario
submission deadline 31 Aug 2024 | 1 articles | Viewed by 1214 | Submission Open
Keywords: alternative sources; animal nutrition; bioactive compounds; metabolites; animal products; consumer health
(This special issue belongs to the Section Animal Metabolism)
Gut Microbe-Derived Metabolites in the Onset of Chronic Diseases
edited by Jonathan Wei Jie Lee and Adrian Low
submission deadline 31 Aug 2024 | 1 articles | Viewed by 495 | Submission Open
Keywords: gut microbiome; chronic gut disease; sulfidogenic bacteria; methanogens; secondary bile acids; short-chain fatty acids; tryptophan metabolites
(This special issue belongs to the Section Microbiology and Ecological Metabolomics)
Editorial Board Members' Collection Series: Microbial Metabolism in Animal Health
edited by
submission deadline 31 Aug 2024 | Viewed by 331 | Submission Open
Keywords: animal health; metabolite markers; metabolomics; microbial metabolism; microbial metabolite; microbial intervention
(This special issue belongs to the Section Animal Metabolism)
Advancement of Microbiome and Metabolomics in Understanding Immune Homeostasis
edited by Bing Ma and Young Suk Lee
submission deadline 31 Aug 2024 | Viewed by 157 | Submission Open
Keywords: microbiome; metabolite; immune homeostasis; host– microbe interaction; integrative multi-omics; microbial ecology; T cell differentiation; regulation
(This special issue belongs to the Section Microbiology and Ecological Metabolomics)
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