- Editorial
2,360 Views
1 Page
Sclerosis is a medical condition characterized by the hardening of tissues and can affect organs, the nervous system, and the vascular system [...]
- 38 daysTime to First Decision
Sclerosis, Volume 1, Issue 1
June 2023 - 8 articles
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Articles (8)
- Case Report
2,903 Views
7 Pages
Isolated Myelopathy in Occult Breast Carcinoma with Negative Paraneoplastic Antibodies: A Case Report of a Rare Condition
- Loredana Paciolla,
- Giulia Galli,
- Domizia Vecchio,
- Samuel Padelli,
- Cristoforo Comi,
- Roberto Cantello and
- Eleonora Virgilio
Isolated paraneoplastic myelopathy (IPM) is a rare neurological manifestation of systemic cancer and represents an intermediate-risk phenotype of disease according to the diagnostic criteria for Paraneoplastic Neurologic Syndromes (PNS). Here, we pre...
- Case Report
2,737 Views
9 Pages
Is It Lupus? Is It Neuromyelitis Optica Spectrum Disorder (NMOSD)?—Why Not Both?
- Niklas Alexander Kaempfer,
- Mathias Fousse,
- Michael Kettner,
- Klaus Fassbender and
- Daniel Janitschke
Multiple sclerosis (MS) and neuromyelitis optica spectrum disorders (NMOSD) are among the commonly considered differential diagnoses in patients with inflammatory central nervous system (CNS)-diseases. Formerly diagnosed competing autoimmune diseases...
- Feature Paper
- Article
9 Citations
6,022 Views
24 Pages
A Pilot Randomised Control Trial of an Online Acceptance and Commitment Therapy (ACT) Resilience Training Program for People with Multiple Sclerosis
- Kenneth I. Pakenham and
- Giulia Landi
Background: This pilot study explored the effectiveness and feasibility of an online version of a group acceptance and commitment therapy (ACT) resilience training intervention for people with multiple sclerosis (PwMS), called e-READY for Multiple Sc...
- Case Report
2,153 Views
5 Pages
COQ7-Related Juvenile-Onset Motor Neuronopathy: A New Pathogenetic Dysfunction Associated with Motor Neuron Disease
- Paulo Victor Sgobbi de Souza,
- Igor Braga Farias,
- Paulo de Lima Serrano,
- Bruno de Mattos Lombardi Badia,
- Ana Carolina dos Santos Jorge,
- Glenda Barbosa Barros,
- Hélvia Bertoldo de Oliveira,
- Samia Rogatis Calil,
- Isabela Danziato Fernandes and
- Roberta Correa Ribeiro
- + 5 authors
A 38-year-old Brazilian man presented with slowly progressive quadriparesis since age 11 years. He progressed over 15 years with symptoms restricted to the lower limbs, and since then, with a progressive compromise of the upper limbs. His deceased br...
- Perspective
2 Citations
8,854 Views
13 Pages
Multiple Sclerosis and Sodium Toxicity: Controversy and Future Directions for Low-Salt Interventions
- Ronald B. Brown
Salt intake is associated with multiple sclerosis; however, controversial findings that challenge this association rely primarily on methods that do not measure total sodium storage within the body, such as food surveys and urinary sodium excretion....
- Case Report
2 Citations
4,281 Views
4 Pages
Anti-Yo Paraneoplastic Cerebellar Degeneration and Breast Cancer: A Long Survival of Persistent Cerebellar Syndrome
- Gianluca Avino,
- Fabiola De Marchi,
- Roberto Cantello and
- Letizia Mazzini
Paraneoplastic neurological syndromes (PNS) occur in 1–3% of all cancer patients with several cancer-related neurologic diseases involving any part of the nervous system. Paraneoplastic cerebellar degeneration (PCD) is a specific type of PNS ch...
- Case Report
1 Citations
2,105 Views
4 Pages
Benign COVID-19 in an Aggressive Case of Aquaporin-4 Neuromyelitis Optica Treated with Tocilizumab
- Domizia Vecchio,
- Claudio Solaro,
- Eleonora Virgilio,
- Paola Naldi,
- Rugiada Bottero,
- Fabio Masuccio,
- Marco Capobianco and
- Roberto Cantello
Aggressive neuromyelitis optica spectrum disorders (NMOSDs) with antibodies (Abs) against aquaporin-4 (AQP4) can be treated by blocking the interleukin 6 (IL6) pathways with tocilizumab. This IL6-inhibitor was employed to treat coronavirus disease 20...
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Sclerosis - ISSN 2813-3064