Announcements

4 July 2023
Metabolites | Top 10 Cited Review Papers in 2021

1. “L-Carnitine and Acylcarnitines: Mitochondrial Biomarkers for Precision Medicine”
*Editor’s Choice Paper
by Marc R. McCann, Mery Vet George De la Rosa, Gus R. Rosania and Kathleen A. Stringer
Metabolites 2021, 11(1), 51; https://doi.org/10.3390/metabo11010051
Available online: https://www.mdpi.com/2218-1989/11/1/51

2. “The Effects of Plant-Associated Bacterial Exopolysaccharides on Plant Abiotic Stress Tolerance”
by Rafael J. L. Morcillo and Maximino Manzanera
Metabolites 2021, 11(6), 337; https://doi.org/10.3390/metabo11060337
Available online: https://www.mdpi.com/2218-1989/11/6/337

3. “Metabolic Reprogramming of Cancer Cells during Tumor Progression and Metastasis”
by Kenji Ohshima and Eiichi Morii
Metabolites 2021, 11(1), 28; https://doi.org/10.3390/metabo11010028
Available online: https://www.mdpi.com/2218-1989/11/1/28

4. “The Effects of SGLT2 Inhibitors on Lipid Metabolism”
by Zsolt Szekeres, Kalman Toth and Eszter Szabados
Metabolites 2021, 11(2), 87; https://doi.org/10.3390/metabo11020087
Available online: https://www.mdpi.com/2218-1989/11/2/87

5. “Vitamin D Sources, Metabolism, and Deficiency: Available Compounds and Guidelines for Its Treatment”
*Editor’s Choice Paper
by Ligia J. Dominguez, Mario Farruggia, Nicola Veronese and Mario Barbagallo
Metabolites 2021, 11(4), 255; https://doi.org/10.3390/metabo11040255
Available online: https://www.mdpi.com/2218-1989/11/4/255

6. “Apolipoprotein B and Cardiovascular Disease: Biomarker and Potential Therapeutic Target”
by Jennifer Behbodikhah, Saba Ahmed, Ailin Elyasi, Lora J. Kasselman, Joshua De Leon, Amy D. Glass and Allison B. Reiss
Metabolites 2021, 11(10), 690; https://doi.org/10.3390/metabo11100690
Available online: https://www.mdpi.com/2218-1989/11/10/690

7. “Linking Gut Microbiome and Lipid Metabolism: Moving beyond Associations”
*Feature Paper
by Santosh Lamichhane, Partho Sen, Marina Amaral Alves, Henrique C. Ribeiro, Peppi Raunioniemi, Tuulia Hyötyläinen and Matej Orešič
Metabolites 2021, 11(1), 55; https://doi.org/10.3390/metabo11010055
Available online: https://www.mdpi.com/2218-1989/11/1/55

8. “Glutathione Metabolism in Plants under Stress: Beyond Reactive Oxygen Species Detoxification”
by Sonia Dorion, Jasmine C. Ouellet and Jean Rivoal
Metabolites 2021, 11(9), 641; https://doi.org/10.3390/metabo11090641
Available online: https://www.mdpi.com/2218-1989/11/9/641

9. “The Chemistry of Stress: Understanding the ‘Cry for Help’ of Plant Roots”
by Muhammad Syamsu Rizaludin, Nejc Stopnisek, Jos M. Raaijmakers and Paolina Garbeva
Metabolites 2021, 11(6), 357; https://doi.org/10.3390/metabo11060357
Available online: https://www.mdpi.com/2218-1989/11/6/357

10. “Sensing and Signaling of Methionine Metabolism”
by Linda Lauinger and Peter Kaiser
Metabolites 2021, 11(2), 83; https://doi.org/10.3390/metabo11020083
Available online: https://www.mdpi.com/2218-1989/11/2/83

3 July 2023
MDPI Insights: The CEO's Letter #1 - Open Access and Impactful Research

Welcome to the MDPI Insights: The CEO's Letter.

In these monthly letters, I will showcase two key aspects of our work at MDPI: our commitment to empowering researchers and our determination to facilitating open scientific exchange.


Opening Thoughts

The Future is Open, and MDPI is Leading the Way

I strongly believe in a future that embraces openness, where open source, open information, and open access (OA) take center stage. This belief that led me to join MDPI in 2020, and I am honored to have recently been appointed as Chief Executive Officer (CEO). In this capacity, and operating in close liaison with Dr. Lin and MDPI’s senior management, I shall work to build on Dr. Lin’s achievements of the past quarter-century. In this role, I will focus on communication initiatives to promote MDPI's remarkable work and continue to build our company as a trusted leader in OA publishing. For over two decades, MDPI has been at the forefront of reshaping the academic publishing landscape, with OA surpassing subscription-based publishing in 2020. This trajectory is deeply rooted in our history and reflects our unwavering commitment and vision for an open future.

1 Million Published Articles

2023 began with a remarkable achievement for MDPI, as we became the first OA publisher to reach the milestone of 1 million published articles. This represents 2.7 million unique authors who have trusted us with their work, or about a third of all researchers worldwide. As the world's most cited OA publisher, we are proud in sharing these significant milestones.

Our mission remains unchanged: to make science open and accessible to all. We understand the importance of knowledge access, empowering researchers to stay at the forefront of a rapidly changing world. Our diverse range of journals covers a wide spectrum of disciplines, offering cutting-edge insights, trusted tools, and crucial knowledge to address global challenges.

Liberating Science

As the world’s leading OA publisher, MDPI is actively liberating science. We are committed to eliminating the frustrations researchers and the general public face when accessing information, ensuring it is not locked behind paywalls. We firmly believe that everyone has a right to information, and our commitment to open access publishing drives our work.

In this inaugural edition of Insights: The CEO's Letter, I draw inspiration from the upcoming 20th anniversary of the Berlin Declaration on Open Access. Its stated mission reminds us that true impact is achieved when knowledge is widely and readily available to society:

"Our mission of disseminating knowledge is only half complete if the information is not made widely and readily available to society”

Impactful Research

MDPI Publishes Impactful Research: Recognized by Leading Indexing Databases

MDPI journals are indexed in every single top database in the world.

As of June 2023, we have 214 journals indexed within Web of Science, 223 indexed within Scopus, 87 indexed within PubMed and PMC, and 17 indexed within MEDLINE, and these numbers increase every month. We constantly strive to expand the coverage of our journals within leading multi-disciplinary and scope-specific databases, resulting in an incredibly broad range of journals that are indexed within a variety of databases. MDPI has active relationships with approximately 65 well-known databases around the world, and we continue to expand our portfolio every year so that your work can be found, cited, and referenced with ease.

Continued Growth of MDPI Journals

The 2022 Scopus and Web of Science journal citation metrics were officially released in June, and I am pleased to report that 31 MDPI journals received their first CiteScore, taking the total number of journals with a CiteScore to 216. The number of MDPI journals receiving an Impact Factor (IF) also continues to grow with 111 receiving their first, by being covered in the ESCI, bringing our total number of journals with an IF to 208 of which 41 journals received an IF above 4.0. Looking at 2022 CiteScores in the Scopus database, 80% of MDPI journals have a score that ranks them in Q1 or Q2 in at least one subject category.

Publishing impactful science would not be possible without all of our authors, editors and reviewers. Thank you for your contribution and continued support! Together we share the latest scientific insights faster and ensure that your work is accessible to all.

Read more

Interview with Indexing Manager—Constanze Shelhorn

Inside MDPI

Preprints.org: Clarivate adds the Preprint Citation Index to the Web of Science

At MDPI, we are dedicated to driving the advancement of science. Through our initiative, Preprints.org, researchers can publish their work and gain valuable feedback from the broader research community, ensuring rapid progress in their respective fields. This is particularly crucial during times of health and climate challenges, where timely dissemination of findings is essential.

Increased Visibility for Preprints

I am pleased to share that Clarivate recognizes the significance of preprints and has taken a crucial step to enhance their visibility. Clarivate has added the Preprint Citation Index to the Web of Science, encompassing preprints published not only on Preprints.org but also on other reputable repositories.

Looking ahead, the future of preprints appears promising, bolstered by the recent indexing announcement from the Web of Science. As a result, preprints will receive increased visibility, serving as a valuable resource for staying informed about the latest research developments.

Read more

What are Preprints?
The Pros and Cons of Preprints
Preprints and COVID-19
Preprints—The Future of Open Access Publishing?

Coming Together for Science

The First International Conference on Antioxidants: Sources, Methods, Health Benefits and Industrial Applications

In this edition of ‘Coming Together for Science,’ I am pleased to highlight the First International Conference on Antioxidants organized by our conference team in the beautiful city of Barcelona, Spain. The conference attracted over 130 attendees, who engaged in 42 talks, and 89 poster presentations spread across several sessions.

Working Together

Under the leadership of Prof. Dr. Alessandra Napolitano (Department of Chemical Sciences, University of Naples ‘Federico II’, Naples, Italy) and Prof. Dr. Rosa M. Lamuela Raventos (Department of Nutrition, Food Sciences and Gastronomy, University of Barcelona, Spain) as chairs, and supported by the committee members, 10 invited keynote speakers, poster presenters, and all the attendees, this dedicated group of academics came together to discuss the natural sources, methodologies, health benefits, and industrial applications of antioxidants.

Especially noteworthy is the positive feedback received from attendees, with 94% rating the overall organization of the conference as good or excellent. I particularly love the picture above, capturing the gathering of some of the participants. You can browse through more photos in the event gallery located here.

Managing Events With Sciforum

If you are considering hosting your own academic event, I highly recommend checking out Sciforum, MDPI's event management platform. Sciforum simplifies the entire process, making it easy to host your own event by allowing you to focus on what really matters: Science!

Read more

Sciforum: forthcoming events
Spotlight on Antioxidants

Closing Thoughts

Stefan Tochev, Dr. Shu-Kun Lin, Dr. Eric O. Freed, Peter Roth, Wynne Wang, Allison Yang

Viruses and Editorial Quality: Acknowledging the Dedication of our Viruses Journal Team

During a June meeting with Dr. Eric O. Freed, the founding and current Editor-in-Chief of our journal Viruses, I was reminded of the exceptional dedication of our editorial board. Meeting with Eric is a pleasure, as he has a strong commitment and clear vision for the journal. Over the course of two days, we gained a deep understanding of the journal’s expectations and focus on strategic growth, editorial board representation, and engagement.

I am pleased to share that Viruses holds a CiteScore of 7.1 (an increase of 7.57% versus the 2021 metric) and an Impact Factor of 4.7. You can view the journal statistics here. Viruses publishes highly cited papers, and is indexed in renowned databases such as Scopus, SCIE (Web of Science), PubMed, and others, and maintains affiliations with prestigious societies. Moreover, the Viruses team has recently announced an exciting upcoming event titled ‘Viruses 2024 – A World of Viruses,’ scheduled to take place in Barcelona, Spain, from 14–16 February 2024.

Testimonials

If you notice my enthusiasm regarding our editorial service, it’s because the surveys and testimonials we receive speak volumes about the experiences of our authors, reviewers, and guest editors who collaborate with MDPI. The purpose of these letters is to highlight the exceptional work that we do and the experiences we create for the scholars – thus, let me end with this testimonial from an author:

“It was a great pleasure to publish in Viruses Special Issue [Emerging Viruses in Aquaculture]. The submission process was easy. Guest editors were very helpful and provided all the guidance and support as needed. The handling of the manuscript by the Editorial Team was very fast, efficient, and professional. The reviewer’s comments were insightful, and the publication processes were remarkably rapid.”
Ms. Magdalena Stachnik, Państwowy Instytut Weterynaryjny | PIWet

Article in Viruses: Emerging Viral Pathogens in Sturgeon Aquaculture in Poland: Focus on Herpesviruses and Mimivirus Detection

Stefan Tochev
Chief Executive Officer
MDPI AG

28 June 2023
2022 Impact Factors for MDPI Journals

The 2022 citation metrics have been released in the Journal Citation Reports (JCR), and we’re pleased to announce the following results for MDPI journals:

We are thrilled to announce that 90% of our ranked MDPI journals, specifically 86 out of 96 (captured in the table below), are performing above average in Q1 or Q2. This year, Clarivate has expanded its Impact Factor (IF) awards to include journals in the Emerging Sources Citation Index (ESCI) and the Arts and Humanities Citation Index (AHCI), providing greater transparency for the full set of journals indexed in the Web of Science Core Collection. As a result, 111 of MDPI journals have received their first IF in 2023, with 37 journals surpassing an IF of 3.0. In total, 208 MDPI journals have been honored with an IF.

Clarivate explains that by "expanding the coverage but holding to highly selective standards, the [Impact Factor] is now a reliable indicator of trustworthiness, as well as a measure of scholarly impact, at the journal level."

Please visit our blog post where we discuss the release of the latest citation metrics with our Indexing Manager, Dr. Constanze Schelhorn, to find out what's different this time around and how to make use of different metrics available.

Journal Impact Factor Rank Quartile Category
Vaccines 7.8 Q1 Immunology
Medicine, Research & Experimental
Antioxidants 7.0 Q1 Food Science & Technology
Biochemistry & Molecular Biology
Chemistry, Medicinal
Cells 6.0 Q2 Cell Biology
Nutrients 5.9 Q1 Nutrition & Dietetics
International Journal of Molecular Sciences 5.6 Q1 Biochemistry & Molecular Biology
Q2 Chemistry, Multidisciplinary
Journal of Theoretical and Applied Electronic Commerce Research 5.6 Q2 Business
Biomolecules 5.5 Q1 Biochemistry & Molecular Biology
Biosensors 5.4 Q1 Chemistry, Analytical
Instruments & Instrumentation
Q2 Nanoscience & Nanotechnology
Fractal and Fractional 5.4 Q1 Mathematics, Interdisciplinary Applications
Marine Drugs 5.4 Q1 Chemistry, Medicinal
Pharmacology & Pharmacy
Pharmaceutics 5.4 Q1 Pharmacology & Pharmacy
Nanomaterials 5.3 Q1 Physics, Applied
Q2 Chemistry, Multidisciplinary
Materials Science, Multidisciplinary
Nanoscience & Nanotechnology
Cancers 5.2 Q2 Oncology
Foods 5.2 Q1 Food Science & Technology
Polymers 5.0 Q1 Polymer Science
Remote Sensing 5.0 Q1 Geosciences, Multidisciplinary
Q2 Remote Sensing
Imaging Science & Photographic Technology
Environmental Sciences
Antibiotics 4.8 Q1 Pharmacology & Pharmacy
Q2 Infectious Diseases
Drones 4.8 Q2 Remote Sensing
Journal of Functional Biomaterials 4.8 Q2 Engineering, Biomedical
Materials Science, Biomaterials
Biomedicines 4.7 Q1 Pharmacology & Pharmacy
Q2 Biochemistry & Molecular Biology
Medicine, Research & Experimental
Journal of Fungi 4.7 Q2 Mycology
Microbiology
Viruses 4.7 Q2 Virology
Bioengineering 4.6 Q2 Engineering, Biomedical
Gels 4.6 Q1 Polymer Science
Molecules 4.6 Q2 Chemistry, Multidisciplinary
Biochemistry & Molecular Biology
Pharmaceuticals 4.6 Q2 Pharmacology & Pharmacy
Chemistry, Medicinal
Toxics 4.6 Q1 Toxicology
Q2 Environmental Sciences
Biomimetics 4.5 Q1 Engineering, Multidisciplinary
Q2 Materials Science, Biomaterials
Microorganisms 4.5 Q2 Microbiology
Plants 4.5 Q1 Plant Sciences
Biology 4.2 Q2 Biology
Chemosensors 4.2 Q2 Instruments & Instrumentation
Chemistry, Analytical
Electrochemistry
Membranes 4.2 Q2 Engineering, Chemical
Materials Science, Multidisciplinary
Chemistry, Physical
Polymer Science
Toxins 4.2 Q1 Toxicology
Q2 Food Science & Technology
Metabolites 4.2 Q2 Biochemistry & Molecular Biology
Batteries 4.0 Q2 Electrochemistry
Materials Science, Multidisciplinary
Q3 Energy & Fuels
Catalysts 3.9 Q2 Chemistry, Physical
Journal of Clinical Medicine 3.9 Q2 Medicine, General & Internal
Land 3.9 Q2 Environmental Studies
Sensors 3.9 Q2 Instruments & Instrumentation
Chemistry, Analytical
Engineering, Electrical & Electronic
Sustainability 3.9 Q2 Environmental Sciences (SCIE)
Environmental Studies (SSCI)
Q3 Green & Sustainable Science & Technology (SCIE)
Green & Sustainable Science & Technology (SSCI)
Buildings 3.8 Q2 Construction & Building Technology
Engineering, Civil
Agronomy 3.7 Q1 Agronomy
Q2 Plant Sciences
Fermentation 3.7 Q2 Biotechnology & Applied Microbiology
Pathogens 3.7 Q2 Microbiology
Agriculture 3.6 Q1 Agronomy
Diagnostics 3.6 Q2 Medicine, General & Internal
Genes 3.5 Q2 Genetics & Heredity
Journal of Intelligence 3.5 Q2 Psychology, Multidisciplinary
Lubricants 3.5 Q2 Engineering, Mechanical
Processes 3.5 Q2 Engineering, Chemical
Coatings 3.4 Q2 Materials Science, Coatings & Films
Physics, Applied
Q3 Materials Science, Multidisciplinary
ISPRS International Journal of Geo-Information 3.4 Q2 Geography, Physical
Q3 Computer Science, Information Systems
Remote Sensing
Materials 3.4 Q2 Metallurgy & Metallurgical Engineering
Physics, Applied
Physics, Condensed Matter
Q3 Materials Science, Multidisciplinary
Chemistry, Physical
Micromachines 3.4 Q2 Instruments & Instrumentation
Physics, Applied
Chemistry, Analytical
Q3 Nanoscience & Nanotechnology
Water 3.4 Q2 Water Resources
Environmental Sciences
Brain Sciences 3.3 Q3 Neurosciences
Energies 3.2 Q3 Energy & Fuels
Fire 3.2 Q1 Forestry
Q2 Ecology
Life 3.2 Q2 Biology
Current Issues in Molecular Biology 3.1 Q3 Biochemistry & Molecular Biology
Horticulturae 3.1 Q1 Horticulture
Animals 3.0 Q1 Agriculture, Dairy & Animal Science
Veterinary Sciences
Insects 3.0 Q1 Entomology
Atmosphere 2.9 Q3 Meteorology & Atmospheric Sciences
Environmental Sciences
Electronics 2.9 Q2 Engineering, Electrical & Electronic
Physics, Applied
Q3 Computer Science, Information Systems
Forests 2.9 Q1 Forestry
Inorganics 2.9 Q2 Chemistry, Inorganic & Nuclear
Journal of Marine Science and Engineering 2.9 Q1 Engineering, Marine
Q2 Oceanography
Engineering, Ocean
Metals 2.9 Q2 Metallurgy & Metallurgical Engineering
Q3 Materials Science, Multidisciplinary
Tropical Medicine and Infectious Disease 2.9 Q2 Tropical Medicine
Parasitology
Q3 Infectious Diseases
Universe 2.9 Q2 Astronomy & Astrophysics
Physics, Particles & Fields
Healthcare 2.8 Q2 Health Policy & Services (SSCI)
Q3 Health Care Sciences & Services (SCIE)
Applied Sciences 2.7 Q2 Engineering, Multidisciplinary
Physics, Applied
Q3 Chemistry, Multidisciplinary
Materials Science, Multidisciplinary
Crystals 2.7 Q2 Crystallography
Q3 Materials Science, Multidisciplinary
Entropy 2.7 Q2 Physics, Multidisciplinary
Magnetochemistry 2.7 Q2 Chemistry, Inorganic & Nuclear
Q3 Chemistry, Physical
Materials Science, Multidisciplinary
Symmetry 2.7 Q2 Multidisciplinary Sciences
Actuators 2.6 Q2 Instruments & Instrumentation
Engineering, Mechanical
Aerospace 2.6 Q1 Engineering, Aerospace
Behavioral Sciences 2.6 Q2 Psychology, Multidisciplinary
Current Oncology 2.6 Q3 Oncology
Machines 2.6 Q2 Engineering, Mechanical
Q3 Engineering, Electrical & Electronic
Medicina 2.6 Q3 Medicine, General & Internal
Separations 2.6 Q3 Chemistry, Analytical
Minerals 2.5 Q2 Mining & Mineral Processing
Mineralogy
Geochemistry & Geophysics
Children 2.4 Q2 Pediatrics
Diversity 2.4 Q2 Biodiversity Conservation
Q3 Ecology
Journal of Cardiovascular Development and Disease 2.4 Q3 Cardiac & Cardiovascular Systems
Mathematics 2.4 Q1 Mathematics
Photonics 2.4 Q3 Optics
Veterinary Sciences 2.4 Q1 Veterinary Sciences
Fishes 2.3 Q2 Marine & Freshwater Biology
Fisheries
Axioms 2.0 Q2 Mathematics, Applied
Systems 1.9 Q2 Social Sciences, Interdisciplinary
Tomography 1.9 Q3 Radiology, Nuclear Medicine & Medical Imaging


Note: The Journal of Personalized Medicine's Impact Factor was omitted in the original release and will be assigned separately. Please find the data on the journal webpage in due course.

Source: 2022 Journal Impact Factors, Journal Citation Reports TM (Clarivate, 2023)

 

8 June 2023
Metabolites | Issue Cover Articles in 2022

The articles below have been selected as 2022 Issue Cover Articles by the Editorial Office of Metabolites (ISSN: 2218-1989). These articles are from multiple fields within the scope of Metabolites, and we hope they can provide insights and references for scholars in related fields.

1. “TrpNet: Understanding Tryptophan Metabolism across Gut Microbiome”
by Yao Lu, Jasmine Chong, Shiqian Shen, Joey-Bahige Chammas, Lorraine Chalifour and Jianguo Xia
Metabolites 2022, 12(1), 10; https://doi.org/10.3390/metabo12010010
Available online: https://www.mdpi.com/2218-1989/12/1/10

2. “The Role of Aspartate Transaminase to Platelet Ratio Index (APRI) for the Prediction of Non-Alcoholic Fatty Liver Disease (NAFLD) in Severely Obese Children and Adolescents”
by Antonello E. Rigamonti, Adele Bondesan, Eugenia Rondinelli, Silvano G. Cella and Alessandro Sartorio
Metabolites 2022, 12(2), 155; https://doi.org/10.3390/metabo12020155
Available online: https://www.mdpi.com/2218-1989/12/2/155

3. “Lipidomic Profiling Identifies Serum Lipids Associated with Persistent Multisite Musculoskeletal Pain”
by Canchen Ma, Ming Liu, Jing Tian, Guangju Zhai, Flavia Cicuttini, Yvette L. Schooneveldt, Peter J. Meikle, Graeme Jones and Feng Pan
Metabolites 2022, 12(3), 206; https://doi.org/10.3390/metabo12030206
Available online: https://www.mdpi.com/2218-1989/12/3/206

4. “Liver and White/Brown Fat Dystrophy Associates with Gut Microbiota and Metabolomic Alterations in 3×Tg Alzheimer’s Disease Mouse Model”
by Maria Angela Guzzardi, Federica La Rosa, Daniela Campani, Maria Carmen Collado, Daniel Monleon, Andrea Cacciato Insilla, Maria Tripodi, Alessandro Zega, Alessia Dattilo, Maurizia Rossana Brunetto et al.
Metabolites 2022, 12(4), 278; https://doi.org/10.3390/metabo12040278
Available online: https://www.mdpi.com/2218-1989/12/4/278

5. “A Metabolomic Severity Score for Airflow Obstruction and Emphysema”
by Suneeta Godbole, Wassim W. Labaki, Katherine A. Pratte, Andrew Hill, Matthew Moll, Annette T. Hastie, Stephen P. Peters, Andrew Gregory, Victor E. Ortega, Dawn DeMeo et al.
Metabolites 2022, 12(5), 368; https://doi.org/10.3390/metabo12050368
Available online: https://www.mdpi.com/2218-1989/12/5/368

6. “Novel Plasma Metabolomic Markers Associated with Diabetes Progression in Older Puerto Ricans”
by Sona Rivas-Tumanyan, Lorena S. Pacheco, Danielle E. Haslam, Liming Liang, Katherine L. Tucker, Kaumudi J. Joshipura and Shilpa N. Bhupathiraju
Metabolites 2022, 12(6), 513; https://doi.org/10.3390/metabo12060513
Available online: https://www.mdpi.com/2218-1989/12/6/513

7. “Multi-Tissue Time-Domain NMR Metabolomics Investigation of Time-Restricted Feeding in Male and Female Nile Grass Rats”
by Hayden Johnson, Thomas Yates, Gary Leedom, Chidambaram Ramanathan, Melissa Puppa, Marie van der Merwe and Aaryani Tipirneni-Sajja
Metabolites 2022, 12(7), 657; https://doi.org/10.3390/metabo12070657
Available online: https://www.mdpi.com/2218-1989/12/7/657

8. “Metabolomics Markers of COVID-19 Are Dependent on Collection Wave”
by Holly-May Lewis, Yufan Liu, Cecile F. Frampas, Katie Longman, Matt Spick, Alexander Stewart, Emma Sinclair, Nora Kasar, Danni Greener, Anthony D. Whetton et al.
Metabolites 2022, 12(8), 713; https://doi.org/10.3390/metabo12080713
Available online: https://www.mdpi.com/2218-1989/12/8/713

9. “Multi-Omic Admission-Based Prognostic Biomarkers Identified by Machine Learning Algorithms Predict Patient Recovery and 30-Day Survival in Trauma Patients”
by Sultan S. Abdelhamid, Jacob Scioscia, Yoram Vodovotz, Junru Wu, Anna Rosengart, Eunseo Sung, Syed Rahman, Robert Voinchet, Jillian Bonaroti, Shimena Li et al.
Metabolites 2022, 12(9), 774; https://doi.org/10.3390/metabo12090774
Available online: https://www.mdpi.com/2218-1989/12/9/774

10. “Substantial Fat Loss in Physique Competitors Is Characterized by Increased Levels of Bile Acids, Very-Long Chain Fatty Acids, and Oxylipins”
by Heikki V. Sarin, Juha J. Hulmi, Youwen Qin, Michael Inouye, Scott C. Ritchie, Susan Cheng, Jeramie D. Watrous, Thien-Tu C. Nguyen, Joseph H. Lee, Zhezhen Jin et al.
Metabolites 2022, 12(10), 928; https://doi.org/10.3390/metabo12100928
Available online: https://www.mdpi.com/2218-1989/12/10/928

11. “Multi-Omics Investigation into Acute Myocardial Infarction: An Integrative Method Revealing Interconnections amongst the Metabolome, Lipidome, Glycome, and Metallome”
by Si Ying Lim, Felicia Li Shea Lim, Inmaculada Criado-Navarro, Xin Hao Yeo, Hiranya Dayal, Sri Dhruti Vemulapalli, Song Jie Seah, Anna Karen Carrasco Laserna, Xiaoxun Yang, Sock Hwee Tan et al.
Metabolites 2022, 12(11), 1080; https://doi.org/10.3390/metabo12111080
Available online: https://www.mdpi.com/2218-1989/12/11/1080

12. “Effects of SLCO1B1 Genetic Variant on Metabolite Profile in Participants on Simvastatin Treatment”
by Lilian Fernandes Silva, Rowmika Ravi, Jagadish Vangipurapu, Anniina Oravilahti and Markku Laakso
Metabolites 2022, 12(12), 1159; https://doi.org/10.3390/metabo12121159
Available online: https://www.mdpi.com/2218-1989/12/12/1159

8 June 2023
Metabolites | Issue Cover Articles in 2021

The articles below have been selected as 2021 Issue Cover Articles by the Editorial Office of Metabolites (ISSN: 2218-1989). These articles are from multiple fields within the scope of Metabolites, and we hope they can provide insights and references for scholars in related fields.

1. “Metabolic Dynamics of In Vitro CD8+ T Cell Activation”
by Joy Edwards-Hicks, Michael Mitterer, Erika L. Pearce and Joerg M. Buescher
Metabolites 2021, 11(1), 12; https://doi.org/10.3390/metabo11010012
Available online: https://www.mdpi.com/2218-1989/11/1/12

2. “Maternal Metabolome in Pregnancy and Childhood Asthma or Recurrent Wheeze in the Vitamin D Antenatal Asthma Reduction Trial”
*Editor’s Choice Paper
by Mengna Huang, Rachel S. Kelly, Su H. Chu, Priyadarshini Kachroo, Gözde Gürdeniz, Bo L. Chawes, Hans Bisgaard, Scott T. Weiss and Jessica Lasky-Su
Metabolites 2021, 11(2), 65; https://doi.org/10.3390/metabo11020065
Available online: https://www.mdpi.com/2218-1989/11/2/65

3. “Quantitative Assessment of Occipital Metabolic and Energetic Changes in Parkinson’s Patients, Using In Vivo 31P MRS-Based Metabolic Imaging at 7T”
by Xiao-Hong Zhu, Byeong-Yeul Lee, Paul Tuite, Lisa Coles, Abhishek G. Sathe, Chi Chen, Jim Cloyd, Walter C. Low, Clifford J. Steer and Wei Chen
Metabolites 2021, 11(3), 145; https://doi.org/10.3390/metabo11030145
Available online: https://www.mdpi.com/2218-1989/11/3/145

4. “Specialized Metabolites from Ribosome Engineered Strains of Streptomyces clavuligerus
by Arshad Ali Shaikh, Louis-Felix Nothias, Santosh K. Srivastava, Pieter C. Dorrestein and Kapil Tahlan
Metabolites 2021, 11(4), 239; https://doi.org/10.3390/metabo11040239
Available online: https://www.mdpi.com/2218-1989/11/4/239

5. “Metabolic View on Human Healthspan: A Lipidome-Wide Association Study”
*Editor’s Choice Paper
by Justin Carrard, Hector Gallart-Ayala, Denis Infanger, Tony Teav, Jonathan Wagner, Raphael Knaier, Flora Colledge, Lukas Streese, Karsten Königstein, Timo Hinrichs et al.
Metabolites 2021, 11(5), 287; https://doi.org/10.3390/metabo11050287
Available online: https://www.mdpi.com/2218-1989/11/5/287

6. “General Unified Microbiome Profiling Pipeline (GUMPP) for Large Scale, Streamlined and Reproducible Analysis of Bacterial 16S rRNA Data to Predicted Microbial Metagenomes, Enzymatic Reactions and Metabolic Pathways”
by Boštjan Murovec, Leon Deutsch and Blaž Stres
Metabolites 2021, 11(6), 336; https://doi.org/10.3390/metabo11060336
Available online: https://www.mdpi.com/2218-1989/11/6/336

7. “Lipidomic Analysis to Assess Oxidative Stress in Acute Coronary Syndrome and Acute Stroke Patients”
*Editor’s Choice Paper
by Martin Malý, Martin Hajšl, Kamila Bechyňská, Ondřej Kučerka, Martin Šrámek, Jiří Suttnar, Alžběta Hlaváčková, Jana Hajšlová and Vít Kosek
Metabolites 2021, 11(7), 412; https://doi.org/10.3390/metabo11070412
Available online: https://www.mdpi.com/2218-1989/11/7/412

8. “Do Mass Spectrometry-Derived Metabolomics Improve the Prediction of Pregnancy-Related Disorders? Findings from a UK Birth Cohort with Independent Validation”
by Nancy McBride, Paul Yousefi, Ulla Sovio, Kurt Taylor, Yassaman Vafai, Tiffany Yang, Bo Hou, Matthew Suderman, Caroline Relton, Gordon C. S. Smith et al.
Metabolites 2021, 11(8), 530; https://doi.org/10.3390/metabo11080530
Available online: https://www.mdpi.com/2218-1989/11/8/530

9. “Analysis of Metabolic Markers in Patients with Chronic Heart Failure Before and After LVAD Implantation”
by Marion S. Hilse, Tom Kretzschmar, Rudin Pistulli, Marcus Franz, Tarek Bekfani, Daniela Haase, Sophie Neugebauer, Michael Kiehntopf, Jan F. Gummert, Hendrik Milting et al.
Metabolites 2021, 11(9), 615; https://doi.org/10.3390/metabo11090615
Available online: https://www.mdpi.com/2218-1989/11/9/615

10. “Dynamics in Anemia Development and Dysregulation of Iron Homeostasis in Hospitalized Patients with COVID-19”
by Lukas Lanser, Francesco Robert Burkert, Rosa Bellmann-Weiler, Andrea Schroll, Sophie Wildner, Gernot Fritsche and Günter Weiss
Metabolites 2021, 11(10), 653; https://doi.org/10.3390/metabo11100653
Available online: https://www.mdpi.com/2218-1989/11/10/653

11. “Cord Blood Metabolome and BMI Trajectory from Birth to Adolescence: A Prospective Birth Cohort Study on Early Life Biomarkers of Persistent Obesity”
by Tingyi Cao, Jiaxuan Zhao, Xiumei Hong, Guoying Wang, Frank B. Hu, Xiaobin Wang and Liming Liang
Metabolites 2021, 11(11), 739; https://doi.org/10.3390/metabo11110739
Available online: https://www.mdpi.com/2218-1989/11/11/739

12. “Plasma Metabolome Normalization in Rheumatoid Arthritis Following Initiation of Methotrexate and the Identification of Metabolic Biomarkers of Efficacy”
by Matthew R. Medcalf, Pooja Bhadbhade, Ted R. Mikuls, James R. O’Dell, Rebekah L. Gundry and Ryan S. Funk
Metabolites 2021, 11(12), 824; https://doi.org/10.3390/metabo11120824
Available online: https://www.mdpi.com/2218-1989/11/12/824

16 May 2023
Meet Us at the 19th Annual International Conference of the Metabolomics Society, 18–22 June 2023, Niagara Falls, Ontario, Canada


Conference: 19th Annual International Conference of the Metabolomics Society

Date: 18–22 June 2023

Place: Niagara Falls Convention Centre, 6815 Stanley Avenue, Niagara Falls, Ontario, Canada L2G 3Y9

Booth: #T12

MDPI will be attending the 19th Annual International Conference of the Metabolomics Society, which will be held from 18 to 22 June 2023 in downtown Niagara Falls, Canada, at the Niagara Falls Convention Centre.

The conference is the official annual meeting of the Metabolomics Society, and the largest metabolomics meeting worldwide. It will cover the major scientific themes of: technology advances; computational metabolomics, statistics, and bioinformatics; metabolomics in health and disease; and metabolomics of plants, food, environment and microbes. A special theme for this conference will focus on mental health, drug addiction and medicinal cannabis. The scientific program will include plenary and keynote talks, three parallel scientific sessions, interactive poster sessions, sponsor lunches, other networking events and a specially organized parallel session to promote metabolomics research in industry. A strong line-up of both introductory and advanced workshops will take place on Sunday, 18 June, and the morning of Monday, 19 June. To complement the exciting scientific program, the conference will offer a welcome reception, vibrant early career events, a conference dinner and other engaging social activities.

The following MDPI journals will be represented:

Please do not hesitate to reach out (metabolites@mdpi.com) if you plan on attending this conference. Our delegates look forward to meeting you in person and answering any questions that you might have.

For more information about the conference, please visit the following website: https://www.metabolomics2023.org/.

10 May 2023
Meet Us at the ATS (American Thoracic Society) Conference 2023, 21–23 May 2023, Washington DC, USA


Conference: ATS (American Thoracic Society) Conference 2023
Date: 21–23 May 2023
Location: Washington DC, USA

MDPI will be attending ATS 2023 as an exhibitor; we welcome researchers from different backgrounds to visit and share their latest ideas with us.

This conference has been organized by the American Thoracic Society, and it will showcase the latest advances and discoveries in respiratory science, patient care and global respiratory health. At the conference, specialists will share and discuss the latest research and its applications to clinical, basic, and translational science in pulmonary, critical care, and sleep medicine.

The following MDPI journals will be represented:

If you are planning to attend this conference, please do not hesitate to talk with us online. Our delegates look forward to meeting you in person at booth #2606, and answering any questions that you may have. For more information about the conference, please visit the following website: https://conference.thoracic.org/.

20 April 2023
Metabolites | Hot Topic Papers Published in 2022 in the “Advances in Metabolomics” Section

1. “Metabolomics and the Multi-Omics View of Cancer”
by David Wishart
Metabolites 2022, 12(2), 154; https://doi.org/10.3390/metabo12020154
Available online: https://www.mdpi.com/2218-1989/12/2/154

2. “Signatures of Mitochondrial Dysfunction and Impaired Fatty Acid Metabolism in Plasma of Patients with Post-Acute Sequelae of COVID-19 (PASC)”
by Vamsi P. Guntur, Travis Nemkov, Esther de Boer, Michael P. Mohning, David Baraghoshi, Francesca I. Cendali, Inigo San-Millán, Irina Petrache and Angelo D’Alessandro
Metabolites 2022, 12(11), 1026; https://doi.org/10.3390/metabo12111026
Available online: https://www.mdpi.com/2218-1989/12/11/1026

3. “Evaluation of Syrosingopine, an MCT Inhibitor, as Potential Modulator of Tumor Metabolism and Extracellular Acidification”
by Chloe Buyse, Nicolas Joudiou, Aude Warscotte, Elena Richiardone, Lionel Mignion, Cyril Corbet and Bernard Gallez
Metabolites 2022, 12(6), 557; https://doi.org/10.3390/metabo12060557
Available online: https://www.mdpi.com/2218-1989/12/6/557

4. “Vertical Transfer of Metabolites Detectable from Newborn’s Dried Blood Spot Samples Using UPLC-MS: A Chemometric Study”
by Alessandra Olarini, Madeleine Ernst, Gözde Gürdeniz, Min Kim, Nicklas Brustad, Klaus Bønnelykke, Arieh Cohen, David Hougaard, Jessica Lasky-Su, Hans Bisgaard et al.
Metabolites 2022, 12(2), 94; https://doi.org/10.3390/metabo12020094
Available online: https://www.mdpi.com/2218-1989/12/2/94

5. “Optimisation of the HS-SPME/GC-MS Approach by Design of Experiments Combined with Chemometrics for the Classification of Cretan Virgin Olive Oils”
by Artemis Lioupi, Ioannis Sampsonidis, Christina Virgiliou, Vassiliki T. Papoti, Kyriaki G. Zinoviadou, Apostolos Spyros and Georgios Theodoridis
Metabolites 2022, 12(2), 114; https://doi.org/10.3390/metabo12020114
Available online: https://www.mdpi.com/2218-1989/12/2/114

6. “Optimization of LC-MS2 Data Acquisition Parameters for Molecular Networking Applied to Marine Natural Products”
by Sam Afoullouss, Agata Balsam, A. Louise Allcock and Olivier P. Thomas
Metabolites 2022, 12(3), 245; https://doi.org/10.3390/metabo12030245
Available online: https://www.mdpi.com/2218-1989/12/3/245

7. “Camu-Camu Reduces Obesity and Improves Diabetic Profiles of Obese and Diabetic Mice: A Dose-Ranging Study”
by Anne Abot, Amandine Brochot, Nicolas Pomié, Eve Wemelle, Céline Druart, Marion Régnier, Nathalie M. Delzenne, Willem M. de Vos, Claude Knauf and Patrice D. Cani
Metabolites 2022, 12(4), 301; https://doi.org/10.3390/metabo12040301
Available online: https://www.mdpi.com/2218-1989/12/4/301

8. “Mendelian Randomization Analysis Identifies Blood Tyrosine Levels as a Biomarker of Non-Alcoholic Fatty Liver Disease”
by Émilie Gobeil, Ina Maltais-Payette, Nele Taba, Francis Brière, Nooshin Ghodsian, Erik Abner, Jérôme Bourgault, Eloi Gagnon, Hasanga D. Manikpurage, Christian Couture et al.
Metabolites 2022, 12(5), 440; https://doi.org/10.3390/metabo12050440
Available online: https://www.mdpi.com/2218-1989/12/5/440

20 April 2023
Metabolites | Hot Topic Papers Published in 2021 in the “Advances in Metabolomics” Section

1. “Gut Microbiota Dysbiosis Is Associated with Elevated Bile Acids in Parkinson’s Disease”
by Peipei Li, Bryan A. Killinger, Elizabeth Ensink, Ian Beddows, Ali Yilmaz, Noah Lubben, Jared Lamp, Meghan Schilthuis, Irving E. Vega, Randy Woltjer et al.
Metabolites 2021, 11(1), 29; https://doi.org/10.3390/metabo11010029
Available online: https://www.mdpi.com/2218-1989/11/1/29

2. “Metabolomics and Lipidomics: Expanding the Molecular Landscape of Exercise Biology”
*Editor’s Choice Paper
by Mehdi R. Belhaj, Nathan G. Lawler and Nolan J. Hoffman
Metabolites 2021, 11(3), 151; https://doi.org/10.3390/metabo11030151
Available online: https://www.mdpi.com/2218-1989/11/3/151

3. “Salivary Metabolomics for Diagnosis and Monitoring Diseases: Challenges and Possibilities”
by Eelis Hyvärinen, Minttu Savolainen, Jopi J. W. Mikkonen and Arja M. Kullaa
Metabolites 2021, 11(9), 587; https://doi.org/10.3390/metabo11090587
Available online: https://www.mdpi.com/2218-1989/11/9/587

4. “Optical Microscopy-Guided Laser Ablation Electrospray Ionization Ion Mobility Mass Spectrometry: Ambient Single Cell Metabolomics with Increased Confidence in Molecular Identification”
*Editor’s Choice Paper
by Michael J. Taylor, Sara Mattson, Andrey Liyu, Sylwia A. Stopka, Yehia M. Ibrahim, Akos Vertes and Christopher R. Anderton
Metabolites 2021, 11(4), 200; https://doi.org/10.3390/metabo11040200
Available online: https://www.mdpi.com/2218-1989/11/4/200

5. “Metabolomics Diagnosis of COVID-19 from Exhaled Breath Condensate”
by Elettra Barberis, Elia Amede, Shahzaib Khoso, Luigi Castello, Pier Paolo Sainaghi, Mattia Bellan, Piero Emilio Balbo, Giuseppe Patti, Diego Brustia, Mara Giordano et al.
Metabolites 2021, 11(12), 847; https://doi.org/10.3390/metabo11120847
Available online: https://www.mdpi.com/2218-1989/11/12/847

6. “Plasma Metabolome and Lipidome Associations with Type 2 Diabetes and Diabetic Nephropathy”
by Yan Ming Tan, Yan Gao, Guoshou Teo, Hiromi W. L. Koh, E Shyong Tai, Chin Meng Khoo, Kwok Pui Choi, Lei Zhou and Hyungwon Choi
Metabolites 2021, 11(4), 228; https://doi.org/10.3390/metabo11040228
Available online: https://www.mdpi.com/2218-1989/11/4/228

7. “Contribution of Metabolomics to the Understanding of NAFLD and NASH Syndromes: A Systematic Review”
by Cristina Piras, Antonio Noto, Luciano Ibba, Martino Deidda, Vassilios Fanos, Sandro Muntoni, Vera Piera Leoni and Luigi Atzori
Metabolites 2021, 11(10), 694; https://doi.org/10.3390/metabo11100694
Available online: https://www.mdpi.com/2218-1989/11/10/694

8. “Metabolomics Studies in Psoriatic Disease: A Review”
by John Koussiouris, Nikita Looby, Melanie Anderson, Vathany Kulasingam and Vinod Chandran
Metabolites 2021, 11(6), 375; https://doi.org/10.3390/metabo11060375
Available online: https://www.mdpi.com/2218-1989/11/6/375

13 April 2023
Metabolites | Hot Topic Papers Published in 2022 in the “Endocrinology and Clinical Metabolic Research” Section

1. “Salivary Metabolomics for Oral Squamous Cell Carcinoma Diagnosis: A Systematic Review”
by Kacper Nijakowski, Dawid Gruszczyński, Dariusz Kopała and Anna Surdacka
Metabolites 2022, 12(4), 294; https://doi.org/10.3390/metabo12040294
Available online: https://www.mdpi.com/2218-1989/12/4/294


2. “Cardiovascular and Renal Effectiveness of GLP-1 Receptor Agonists vs. Other Glucose-Lowering Drugs in Type 2 Diabetes: A Systematic Review and Meta-Analysis of Real-World Studies”
by Irene Caruso, Angelo Cignarelli, Gian Pio Sorice, Annalisa Natalicchio, Sebastio Perrini, Luigi Laviola and Francesco Giorgino
Metabolites 2022, 12(2), 183; https://doi.org/10.3390/metabo12020183
Available online: https://www.mdpi.com/2218-1989/12/2/183


3. “The Role of Nutraceutical Containing Polyphenols in Diabetes Prevention”
by Iva Fernandes, Joana Oliveira, Aryane Pinho and Eugenia Carvalho
Metabolites 2022, 12(2), 184; https://doi.org/10.3390/metabo12020184
Available online: https://www.mdpi.com/2218-1989/12/2/184


4. “Emerging Role of Nuclear Receptors for the Treatment of NAFLD and NASH”
by Ryan D. Welch, Cyrielle Billon, McKenna Losby, Gonzalo Bedia-Diaz, Yuanying Fang, Amer Avdagic, Bahaa Elgendy, Thomas P. Burris and Kristine Griffett
Metabolites 2022, 12(3), 238; https://doi.org/10.3390/metabo12030238
Available online: https://www.mdpi.com/2218-1989/12/3/238


5. “Extracellular Matrix in Heart Disease: Focus on Circulating Collagen Type I and III Derived Peptides as Biomarkers of Myocardial Fibrosis and Their Potential in the Prognosis of Heart Failure: A Concise Review”
by Asparuh Nikolov and Nikola Popovski
Metabolites 2022, 12(4), 297; https://doi.org/10.3390/metabo12040297
Available online: https://www.mdpi.com/2218-1989/12/4/297


6. “Fetuin-A in Activated Liver Macrophages Is a Key Feature of Non-Alcoholic Steatohepatitis”
by Quentin Etienne, Valérie Lebrun, Mina Komuta, Benoît Navez, Jean-Paul Thissen, Isabelle A. Leclercq and Nicolas Lanthier
Metabolites 2022, 12(7), 625; https://doi.org/10.3390/metabo12070625
Available online: https://www.mdpi.com/2218-1989/12/7/625


7. “Assessment of Fruit and Vegetables Intake with Biomarkers in Children and Adolescents and Their Level of Validation: A Systematic Review”
by Li Yuan, Samuel Muli, Inge Huybrechts, Ute Nöthlings, Wolfgang Ahrens, Augustin Scalbert and Anna Floegel
Metabolites 2022, 12(2), 126; https://doi.org/10.3390/metabo12020126
Available online: https://www.mdpi.com/2218-1989/12/2/126


8. “The Intestinal Barrier—Shielding the Body from Nano- and Microparticles in Our Diet”
by Marlene Schwarzfischer and Gerhard Rogler
Metabolites 2022, 12(3), 223; https://doi.org/10.3390/metabo12030223
Available online: https://www.mdpi.com/2218-1989/12/3/223

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