Announcements

1. “Altered Expression of DAAM1 and PREP Induced by Cadmium Toxicity Is Counteracted by Melatonin in the Rat Testis”
by Massimo Venditti, Mariem Ben Rhouma, Maria Zelinda Romano, Imed Messaoudi, Russel J. Reiter and Sergio Minucci
Genes 2021, 12(7), 1016; https://doi.org/10.3390/genes12071016
Full text available online: https://www.mdpi.com/2073-4425/12/7/1016

2. “Genetics and Epigenetics in Allergic Rhinitis”
by Choi, Bo Yoon, Munsoo Han, Ji Won Kwak and Tae Hoon Kim
Genes 2021, 12(12), 2004; https://doi.org/10.3390/genes12122004
Full text available online: https://www.mdpi.com/2073-4425/12/12/2004

3. “LINCking the Nuclear Envelope to Sperm Architecture”
by Francesco Manfrevola, Florian Guillou, Silvia Fasano, Riccardo Pierantoni and Rosanna Chianese
Genes 2021, 12(5), 658; https://doi.org/10.3390/genes12050658
Full text available online: https://www.mdpi.com/2073-4425/12/5/658

4. “Evolution of Reproductive Life History in Mammals and the Associated Change of Functional Constraints”
by Jiaqi Wu, Takahiro Yonezawa and Hirohisa Kishino
Genes 2021, 12(5), 740; https://doi.org/10.3390/genes12050740
Full text available online: https://www.mdpi.com/2073-4425/12/5/740

5. “Pediatric and Adolescent Oncofertility in Male Patients—From Alpha to Omega”
by Ovidiu Bîcă, Ioan Sârbu and Carmen Iulia Ciongradi
Genes 2021, 12(5), 701; https://doi.org/10.3390/genes12050701
Full text available online: https://www.mdpi.com/2073-4425/12/5/701

6. “Methylation of Host Genes Associated with Coronavirus Infection from Birth to 26 Years”
by Rutu Rathod, Aniruddha Rathod, Parnian Kheirkhah Rahimabad, Jiasong Duan, Hongmei Zhang, S. Hasan Arshad and Wilfried Karmaus
Genes 2021, 12(8), 1198; https://doi.org/10.3390/genes12081198
Full text available online: https://www.mdpi.com/2073-4425/12/8/1198

7. “Prospects in Connecting Genetic Variation to Variation in Fertility in Male Bees”
by Garett P. Slater, Nicholas M. A. Smith and Brock A. Harpur
Genes 2021, 12(8), 1251; https://doi.org/10.3390/genes12081251
Full text available online: https://www.mdpi.com/2073-4425/12/8/1251

8. “Identification of Long Non-Coding RNAs Involved in Porcine Fat Deposition Using Two High-Throughput Sequencing Methods”
by Yibing Liu, Ying Yu, Hong Ao, Fengxia Zhang, Xitong Zhao, Huatao Liu, Yong Shi, Kai Xing and Chuduan Wang
Genes 2021, 12(9), 1374; https://doi.org/10.3390/genes12091374
Full text available online: https://www.mdpi.com/2073-4425/12/9/1374

9. “Epigenetic Regulation of CDH1 Is Altered after HOXB7-Silencing in MDA-MB-468 Triple-Negative Breast Cancer Cells”
by Ana Paço, Joana Leitão-Castro and Renata Freitas
Genes 2021, 12(10), 1575; https://doi.org/10.3390/genes12101575
Full text available online: https://www.mdpi.com/2073-4425/12/10/1575

10. “Aberrant DNA Methylation Mediates the Transgenerational Risk of Metabolic and Chronic Disease Due to Maternal Obesity and Overnutrition”
by Yan Li, Carol A. Pollock and Sonia Saad
Genes 2021, 12(11), 1653; https://doi.org/10.3390/genes12111653
Full text available online: https://www.mdpi.com/2073-4425/12/11/1653

1. “The Changing Epidemiology of Cystic Fibrosis: Incidence, Survival and Impact of the CFTR Gene Discovery”
by Virginie Scotet, Carine L’Hostis and Claude Férec
Genes 2020, 11(6), 589; https://doi.org/10.3390/genes11060589
Full text available online: https://www.mdpi.com/2073-4425/11/6/589

2. “COVID-19 and Genetic Variants of Protein Involved in the SARS-CoV-2 Entry into the Host Cells”
by Andrea Latini, Emanuele Agolini, Antonio Novelli, Paola Borgiani, Rosalinda Giannini, Paolo Gravina, Andrea Smarrazzo, Mario Dauri, Massimo Andreoni, Paola Rogliani et al.
Genes 2020, 11(9), 1010; https://doi.org/10.3390/genes11091010
Full text available online: https://www.mdpi.com/2073-4425/11/9/1010

3. “Regulation of mTORC2 Signaling”     
by Wenxiang Fu and Michael N. Hall
Genes 2020, 11(9), 1045; https://doi.org/10.3390/genes11091045
Full text available online: https://www.mdpi.com/2073-4425/11/9/1045

4. “A Review of the Important Role of CYP2D6 in Pharmacogenomics”
by Christopher Taylor, Ian Crosby, Vincent Yip, Peter Maguire, Munir Pirmohamed and Richard M. Turner
Genes 2020, 11(11), 1295; https://doi.org/10.3390/genes11111295
Full text available online: https://www.mdpi.com/2073-4425/11/11/1295

5. “Mechanisms of Photoreceptor Death in Retinitis Pigmentosa”
by Fay Newton and Roly Megaw
Genes 2020, 11(10), 1120; https://doi.org/10.3390/genes11101120
Full text available online: https://www.mdpi.com/2073-4425/11/10/1120

6. “Therapeutic Strategies for Duchenne Muscular Dystrophy: An Update”
by Chengmei Sun, Luoan Shen, Zheng Zhang and Xin Xie
Genes 2020, 11(8), 837; https://doi.org/10.3390/genes11080837
Full text available online: https://www.mdpi.com/2073-4425/11/8/837

7. “RET Gene Fusions in Malignancies of the Thyroid and Other Tissues”
by Massimo Santoro, Marialuisa Moccia, Giorgia Federico and Francesca Carlomagno
Genes 2020, 11(4), 424; https://doi.org/10.3390/genes11040424
Full text available online: https://www.mdpi.com/2073-4425/11/4/424

8. “The Microbiome in Cystic Fibrosis Pulmonary Disease”
by Alice Françoise and Geneviève Héry-Arnaud
Genes 2020, 11(5), 536; https://doi.org/10.3390/genes11050536
Full text available online: https://www.mdpi.com/2073-4425/11/5/536 

9. “Extracellular Vesicles Derived from Human Gingival Mesenchymal Stem Cells: A Transcriptomic Analysis”
by Serena Silvestro, Luigi Chiricosta, Agnese Gugliandolo, Jacopo Pizzicannella, Francesca Diomede, Placido Bramanti, Oriana Trubiani and Emanuela Mazzon
Genes 2020, 11(2), 118; https://doi.org/10.3390/genes11020118
Full text available online: https://www.mdpi.com/2073-4425/11/2/118

10. “The Roles of the NLRP3 Inflammasome in Neurodegenerative and Metabolic Diseases and in Relevant Advanced Therapeutic Interventions”
by Rameez Hassan Pirzada, Nasir Javaid and Sangdun Choi
Genes 2020, 11(2), 131; https://doi.org/10.3390/genes11020131
Full text available online: https://www.mdpi.com/2073-4425/11/2/131

MDPI has just become the first open access (OA) publisher to reach the milestone of one million articles published. That is one million articles freely available to all, to circulate and build upon! We are proud to share this special moment with the global scientific community.

This landmark has been reached thanks to the immeasurable support of more than 600,000 expert reviewers, 66,000 editorial board members and 6700 hard-working colleagues across MDPI’s global offices.

Within more than 25 years of publishing, our journals received 2.1 million manuscripts and generated 4.6 million peer review reports to get to one million papers published.

Reaching the milestone of one million articles published reinforces our mission to remove any existing barriers and to make scientific research accessible to all. Since its inception, MDPI’s goal has been to create reliable processes to make science open. This is a path towards facilitating the dissemination of novel insights in scientific communities.

Regular feedback from authors and reviewers shows that our service is greatly appreciated and needed. At the same time, the feedback helps us identify areas for further improvement.

As it stands, a significant share of published research findings remain closed access. More than half of the content published with the most well-known legacy publishers stays behind a paywall, and that is not including articles published in hybrid OA journals, or made available months or years after publication.

A new policy announced by the US administration in August 2022 requires that, as of January 2026, all US federally funded research be made freely and immediately available after publication. While the new policy does not mandate articles be published under an open access license, it is aligned with the open access movement in removing all barriers to research. Similarly, some of the most advanced research institutions in the world intend to have all funded research articles published in open access by 2025.

MDPI is proud to be the leading agent of the transition to open access.

"Thanks a Million" to all the contributors!

1. “Genomics in Bacterial Taxonomy: Impact on the Genus Pseudomonas”
by Jorge Lalucat, Magdalena Mulet, Margarita Gomila and Elena García-Valdés
Genes 2020, 11(2), 139; https://doi.org/10.3390/genes11020139
Full text available online: https://www.mdpi.com/2073-4425/11/2/139

2. “Plasmid Transfer by Conjugation in Gram-Negative Bacteria: From the Cellular to the Community Level”
by Chloé Virolle, Kelly Goldlust, Sarah Djermoun, Sarah Bigot and Christian Lesterlin
Genes 2020, 11(11), 1239; https://doi.org/10.3390/genes11111239
Full text available online: https://www.mdpi.com/2073-4425/11/11/1239 

3. “Farnesol and Tyrosol: Secondary Metabolites with a Crucial quorum-sensing Role in Candida Biofilm Development”
by Célia F. Rodrigues and Lucia Černáková
Genes 2020, 11(4), 444; https://doi.org/10.3390/genes11040444  
Full text available online: https://www.mdpi.com/2073-4425/11/4/444

4. “Butyrate Levels in the Transition from an Infant- to an Adult-Like Gut Microbiota Correlate with Bacterial Networks Associated with Eubacterium Rectale and Ruminococcus Gnavus”
by Morten Nilsen, Carina Madelen Saunders, Inga Leena Angell, Magnus Ø. Arntzen, Karin C. Lødrup Carlsen, Kai-Håkon Carlsen, Guttorm Haugen, Live Heldal Hagen, Monica H. Carlsen, Gunilla Hedlin et al.
Genes 2020, 11(11), 1245; https://doi.org/10.3390/genes11111245  
Full text available online: https://www.mdpi.com/2073-4425/11/11/1245

5. “Genes, Pathways, and Mechanisms Involved in the Virulence of Mucorales”
by Carlos Lax, Carlos Pérez-Arques, María Isabel Navarro-Mendoza, José Tomás Cánovas-Márquez, Ghizlane Tahiri, José Antonio Pérez-Ruiz, Macario Osorio-Concepción, Laura Murcia-Flores, Eusebio Navarro, Victoriano Garre et al.
Genes 2020, 11(3), 317; https://doi.org/10.3390/genes11030317  
Full text available online: https://www.mdpi.com/2073-4425/11/3/317

6. “Comparison of Illumina versus Nanopore 16S rRNA Gene Sequencing of the Human Nasal Microbiota”
by Astrid P. Heikema, Deborah Horst-Kreft, Stefan A. Boers, Rick Jansen, Saskia D. Hiltemann, Willem de Koning, Robert Kraaij, Maria A. J. de Ridder, Chantal B. van Houten, Louis J. Bont et al.
Genes 2020, 11(9), 1105; https://doi.org/10.3390/genes11091105  
Full text available online: https://www.mdpi.com/2073-4425/11/9/1105

7. “Of Drugs and Trypanosomatids: New Tools and Knowledge to Reduce Bottlenecks in Drug Discovery”
by Arijit Bhattacharya, Audrey Corbeil, Rubens L. do Monte-Neto and Christopher Fernandez-Prada
Genes 2020, 11(7), 722; https://doi.org/10.3390/genes11070722  
Full text available online: https://www.mdpi.com/2073-4425/11/7/722

8. “Comparative Genomic Analysis of Lactiplantibacillus plantarum Isolated from Different Niches”
by Bingyong Mao, Ruimin Yin, Xiaoshu Li, Shumao Cui, Hao Zhang, Jianxin Zhao and Wei Chen
Genes 2021, 12(2), 241; https://doi.org/10.3390/genes12020241  
Full text available online: https://www.mdpi.com/2073-4425/12/2/241 

9. “Comparative Genomics Analysis of Lactobacillus ruminis from Different Niches”
by Shuo Wang, Bo Yang, R. Paul Ross, Catherine Stanton, Jianxin Zhao, Hao Zhang and Wei Chen
Genes 2020, 11(1), 70; https://doi.org/10.3390/genes11010070  
Full text available online: https://www.mdpi.com/2073-4425/11/1/70

10. “Hybridization Facilitates Adaptive Evolution in Two Major Fungal Pathogens”
by Himeshi Samarasinghe, Man You, Thomas S. Jenkinson, Jianping Xu and Timothy Y. James
Genes 2020, 11(1), 101; https://doi.org/10.3390/genes11010101  
Full text available online: https://www.mdpi.com/2073-4425/11/1/101

1. “Genetic Modifiers and Rare Mendelian Disease”
by K. M. Tahsin Hassan Rahit and Maja Tarailo-Graovac
Genes 2020, 11(3), 239; https://doi.org/10.3390/genes11030239
Full text available online: https://www.mdpi.com/2073-4425/11/3/239

2. “Rapid Direct Nucleic Acid Amplification Test without RNA Extraction for SARS-CoV-2 Using a Portable PCR Thermocycler”
by Soon Keong Wee, Suppiah Paramalingam Sivalingam and Eric Peng Huat Yap
Genes 2020, 11(6), 664; https://doi.org/10.3390/genes11060664
Full text available online: https://www.mdpi.com/2073-4425/11/6/664 

3. “Relative Abundance of SARS-CoV-2 Entry Genes in the Enterocytes of the Lower Gastrointestinal Tract”
by Jaewon J. Lee, Scott Kopetz, Eduardo Vilar, John Paul Shen, Ken Chen and Anirban Maitra
Genes 2020, 11(6), 645; https://doi.org/10.3390/genes11060645
Full text available online: https://www.mdpi.com/2073-4425/11/6/645

4. “Whole Genome Sequencing of SARS-CoV-2: Adapting Illumina Protocols for Quick and Accurate Outbreak Investigation during a Pandemic”
by Sureshnee Pillay, Jennifer Giandhari, Houriiyah Tegally, Eduan Wilkinson, Benjamin Chimukangara, Richard Lessells, Yunus Moosa, Stacey Mattison, Inbal Gazy, Maryam Fish et al.
Genes 2020, 11(8), 949; https://doi.org/10.3390/genes11080949
Full text available online: https://www.mdpi.com/2073-4425/11/8/949

5. “mRNAsi Index: Machine Learning in Mining Lung Adenocarcinoma Stem Cell Biomarkers”
by Yitong Zhang, Joseph Ta-Chien Tseng, I-Chia Lien, Fenglan Li, Wei Wu and Hui Li
Genes 2020, 11(3), 257; https://doi.org/10.3390/genes11030257
Full text available online: https://www.mdpi.com/2073-4425/11/3/257

6. “Standards for Methods Utilizing Environmental DNA for Detection of Fish Species”
by Lu Shu, Arne Ludwig and Zuogang Peng
Genes 2020, 11(3), 296; https://doi.org/10.3390/genes11030296
Full text available online: https://www.mdpi.com/2073-4425/11/3/296

7. “Analytical Sensitivity and Specificity of Two RT-qPCR Protocols for SARS-CoV-2 Detection Performed in an Automated Workflow”
by Gustavo Barcelos Barra, Ticiane Henriques Santa Rita, Pedro Góes Mesquita, Rafael Henriques Jácomo and Lídia Freire Abdalla Nery
Genes 2020, 11(10), 1183; https://doi.org/10.3390/genes11101183
Full text available online: https://www.mdpi.com/2073-4425/11/10/1183

8. “Delivery Approaches for Therapeutic Genome Editing and Challenges”
by Ilayda Ates, Tanner Rathbone, Callie Stuart, P. Hudson Bridges and Renee N. Cottle
Genes 2020, 11(10), 1113; https://doi.org/10.3390/genes11101113
Full text available online: https://www.mdpi.com/2073-4425/11/10/1113

9. “An Improved Phenotype-Driven Tool for Rare Mendelian Variant Prioritization: Benchmarking Exomiser on Real Patient Whole-Exome Data”
by Valentina Cipriani, Nikolas Pontikos, Gavin Arno, Panagiotis I. Sergouniotis, Eva Lenassi, Penpitcha Thawong, Daniel Danis, Michel Michaelides, Andrew R. Webster, Anthony T. Moore et al.
Genes 2020, 11(4), 460; https://doi.org/10.3390/genes11040460
Full text available online: https://www.mdpi.com/2073-4425/11/4/460

10. “DNA6mA-MINT: DNA-6mA Modification Identification Neural Tool”
by Mobeen Ur Rehman and Kil To Chong
Genes 2020, 11(8), 898; https://doi.org/10.3390/genes11080898
Full text available online: https://www.mdpi.com/2073-4425/11/8/898

1. “Subcellular Localization of miRNAs and Implications in Cellular Homeostasis”
by Minwen Jie, Tong Feng, Wei Huang, Moran Zhang, Yuliang Feng, Hao Jiang and Zhili Wen
Genes 2021, 12(13), 856; https://doi.org/10.3390/genes12060856
Full text available online: https://www.mdpi.com/2073-4425/12/6/856

2. “Ribosomal RNA Transcription Regulation in Breast Cancer”
by Cecelia M. Harold, Amber F. Buhagiar, Yan Cheng and Susan J. Baserga
Genes 2021, 12(4), 502; https://doi.org/10.3390/genes12040502
Full text available online: https://www.mdpi.com/2073-4425/12/4/502

3. “Hsa-miR-375/RASD1 Signaling May Predict Local Control in Early Breast Cancer”
by Barbara Zellinger, Ulrich Bodenhofer, Immanuela A. Engländer, Cornelia Kronberger, Peter Strasser, Brane Grambozov, Gerd Fastner, Markus Stana, Roland Reitsamer Karl Sotlar et al.
Genes 2020, 11(2), 1404; https://doi.org/10.3390/genes11121404
Full text available online: https://www.mdpi.com/2073-4425/11/12/1404

4. “Essential Role of the 14q32 Encoded miRNAs in Endocrine Tumors”
by Lilla Krokker, Attila Patócs and Henriett Butz
Genes 2021, 12(5), 698; https://doi.org/10.3390/genes12050698
Full text available online: https://www.mdpi.com/2073-4425/12/5/698

5. “The Ribosomal Gene Loci—The Power behind the Throne”
by Konstantin I. Panov, Katherine Hannan, Ross D. Hannan and Nadine Hein
Genes 2021, 12(5), 763; https://doi.org/10.3390/genes12050763
Full text available online: https://www.mdpi.com/2073-4425/12/5/763

6. “Spt4 Promotes Pol I Processivity and Transcription Elongation”
by Abigail K. Huffines, Yvonne J. K. Edwards and David A. Schneider
Genes 2021, 12(3), 413; https://doi.org/10.3390/genes12030413
Full text available online: https://www.mdpi.com/2073-4425/12/3/413

7. “Harnessing the Nucleolar DNA Damage Response in Cancer Therapy”
by Jiachen Xuan, Kezia Gitareja, Natalie Brajanovski and Elaine Sanij
Genes 2021, 12(8), 1156; https://doi.org/10.3390/genes12081156
Full text available online: https://www.mdpi.com/2073-4425/12/8/1156

8. “Pincho: A Modular Approach to High Quality De Novo Transcriptomics”
by Randy Ortiz, Priyanka Gera, Christopher Rivera and Juan C. Santos
Genes 2021, 12(7), 953; https://doi.org/10.3390/genes12070953
Full text available online: https://www.mdpi.com/2073-4425/12/7/953

9. “DNA Intercalators Inhibit Eukaryotic Ribosomal RNA Synthesis by Impairing the Initiation of Transcription”
by William J. Andrews, Swagat Ray, Tatiana Panova, Christoph Engel and Konstantin I. Panov
Genes 2021, 12(9), 1412; https://doi.org/10.3390/genes12091412
Full text available online: https://www.mdpi.com/2073-4425/12/9/1412

10. “Computational Identification of Sex-Biased Biomarker MicroRNAs and Genes Associated with Immune Infiltration in Breast Cancer”
by Eric W. Li and Yongsheng Bai
Genes 2021, 12(4), 570; https://doi.org/10.3390/genes12040570
Full text available online: https://www.mdpi.com/2073-4425/12/4/570

1. “Histone Deacetylases (HDACs): Evolution, Specificity, Role in Transcriptional Complexes, and Pharmacological Actionability”
by Giorgio Milazzo, Daniele Mercatelli, Giulia Di Muzio, Luca Triboli, Piergiuseppe De Rosa, Giovanni Perini and Federico M. Giorgi
Genes 2020, 11(5), 556; https://doi.org/10.3390/genes11050556
Full text available online: https://www.mdpi.com/2073-4425/11/5/556

2. “Mutation Patterns of Human SARS-CoV-2 and Bat RaTG13 Coronavirus Genomes Are Strongly Biased Towards C>U Transitions, Indicating Rapid Evolution in Their Hosts”
by Roman Matyášek and Aleš Kovařík
Genes 2020, 11(7), 761; https://doi.org/10.3390/genes11070761
Full text available online: https://www.mdpi.com/2073-4425/11/7/761

3. “Trans-Atlantic Distribution and Introgression as Inferred from Single Nucleotide Polymorphism: Mussels Mytilus and Environmental Factors”
by Roman Wenne, Małgorzata Zbawicka, Lis Bach, Petr Strelkov, Mikhail Gantsevich, Piotr Kukliński, Tomasz Kijewski, John H. McDonald, Kristil Kindem Sundsaasen, Mariann Árnyasi et al.
Genes 2020, 11(5), 530; https://doi.org/10.3390/genes11050530
Full text available online: https://www.mdpi.com/2073-4425/11/5/530

4. “The Biochemistry of Cytoplasmic Incompatibility Caused by Endosymbiotic Bacteria”
by Hongli Chen, Mengwen Zhang and Mark Hochstrasser
Genes 2020, 11(8), 852; https://doi.org/10.3390/genes11080852
Full text available online: https://www.mdpi.com/2073-4425/11/8/852

5. “The Female-Specific W Chromosomes of Birds Have Conserved Gene Contents but Are Not Feminized”
by Luohao Xu and Qi Zhou
Genes 2020, 11(10), 1126; https://doi.org/10.3390/genes11101126
Full text available online: https://www.mdpi.com/2073-4425/11/10/1126

6. “Climate Change and Green Sea Turtle Sex Ratio—Preventing Possible Extinction”
by Jana Blechschmidt, Meike J. Wittmann and Chantal Blüml
Genes 2020, 11(5), 588; https://doi.org/10.3390/genes11050588
Full text available online: https://www.mdpi.com/2073-4425/11/5/588

7. “How Depressing Is Inbreeding? A Meta-Analysis of 30 Years of Research on the Effects of Inbreeding in Livestock”
by Harmen P. Doekes, Piter Bijma and Jack J. Windig
Genes 2021, 12(6), 926; https://doi.org/10.3390/genes12060926
Full text available online: https://www.mdpi.com/2073-4425/12/6/926

8. “Genomic Diversity, Population Structure, and Signature of Selection in Five Chinese Native Sheep Breeds Adapted to Extreme Environments”
by Adam Abied, Alnoor Bagadi, Farhad Bordbar, Yabin Pu, Serafino M. A. Augustino, Xianglan Xue, Feng Xing, Gebremedhin Gebreselassie, Jian-Lin Han, Joram M. Mwacharo et al.
Genes 2020, 11(5), 494; https://doi.org/10.3390/genes11050494
Full text available online: https://www.mdpi.com/2073-4425/11/5/494

9. “Interstitial Telomeric Repeats Are Rare in Turtles”
by Lorenzo Clemente, Sofia Mazzoleni, Eleonora Pensabene Bellavia, Barbora Augstenová, Markus Auer, Peter Praschag, Tomáš Protiva, Petr Velenský, Philipp Wagner, Uwe Fritz et al.
Genes 2020, 11(6), 657; https://doi.org/10.3390/genes11060657
Full text available online: https://www.mdpi.com/2073-4425/11/6/657

10. “Highly Rearranged Karyotypes and Multiple Sex Chromosome Systems in Armored Catfishes from the Genus Harttia (Teleostei, Siluriformes)”
by Geize Aparecida Deon, Larissa Glugoski, Marcelo Ricardo Vicari, Viviane Nogaroto, Francisco de Menezes Cavalcante Sassi, Marcelo de Bello Cioffi, Thomas Liehr, Luiz Antonio Carlos Bertollo and Orlando Moreira-Filho
Genes 2020, 11(11), 1366; https://doi.org/10.3390/genes11111366
Full text available online: https://www.mdpi.com/2073-4425/11/11/1366

1. “Transcriptional Factors Regulate Plant Stress Responses Through Mediating Secondary Metabolism”
by Tehseen Ahmad Meraj, Jingye Fu, Muhammad Ali Raza, Chenying Zhu, Qinqin Shen, Dongbei Xu and Qiang Wang
Genes 2020, 11(4), 346; https://doi.org/10.3390/genes11040346
Available online: https://doi.org/10.3390/genes11040346

2. “Down Regulation and Loss of Auxin Response Factor 4 Function Using CRISPR/Cas9 Alters Plant Growth, Stomatal Function and Improves Tomato Tolerance to Salinity and Osmotic Stress”
by Sarah Bouzroud, Karla Gasparini, Guojian Hu, Maria Antonia Machado Barbosa, Bruno Luan Rosa, Mouna Fahr, Najib Bendaou, Mondher Bouzayen, Agustin Zsögön, Abdelaziz Smouni et al.
Genes 2020, 11(3), 272; https://doi.org/10.3390/genes11030272
Available online: https://doi.org/10.3390/genes11030272

3. “The AP2/ERF Gene Family in Triticum durum: Genome-Wide Identification and Expression Analysis under Drought and Salinity Stresses”
by Sahar Faraji, Ertugrul Filiz, Seyed Kamal Kazemitabar, Alessandro Vannozzi, Fabio Palumbo, Gianni Barcaccia and Parviz Heidari
Genes 2020, 11(12), 1464; https://doi.org/10.3390/genes11121464
Available online: https://doi.org/10.3390/genes11121464

4. “Controlling Apomixis: Shared Features and Distinct Characteristics of Gene Regulation”
by Anja Schmidt
Genes 2020, 11(3), 329; https://doi.org/10.3390/genes11030329
Available online: https://doi.org/10.3390/genes11030329

5. “Harnessing Crop Wild Diversity for Climate Change Adaptation”
by Andrés J. Cortés and Felipe López-Hernández
Genes 2021, 12(5), 783; https://doi.org/10.3390/genes12050783
Available online: https://doi.org/10.3390/genes12050783

6. “Genome-Wide Analysis of Potassium Channel Genes in Rice: Expression of the OsAKT and OsKAT Genes under Salt Stress”
by Zahra Musavizadeh, Hamid Najafi-Zarrini, Seyed Kamal Kazemitabar, Seyed Hamidreza Hashemi, Sahar Faraji, Gianni Barcaccia and Parviz Heidari
Genes 2021, 12(5), 784; https://doi.org/10.3390/genes12050784
Available online: https://doi.org/10.3390/genes12050784

7. “Low Temperature Promotes Anthocyanin Biosynthesis and Related Gene Expression in the Seedlings of Purple Head Chinese Cabbage (Brassica rapa L.)”
by Qiong He, Yanjing Ren, Wenbin Zhao, Ru Li and Lugang Zhang
Genes 2020, 11(1), 81; https://doi.org/10.3390/genes11010081
Available online: https://doi.org/10.3390/genes11010081

8. “Plants’ Epigenetic Mechanisms and Abiotic Stress”
by Matin Miryeganeh
Genes 2021, 12(8), 1106; https://doi.org/10.3390/genes12081106
Available online: https://doi.org/10.3390/genes12081106

9. “HD-ZIP Gene Family: Potential Roles in Improving Plant Growth and Regulating Stress-Responsive Mechanisms in Plants”
by Rahat Sharif, Ali Raza, Peng Chen, Yuhong Li, Enas M. El-Ballat, Abdur Rauf, Christophe Hano and Mohamed A. El-Esawi
Genes 2021, 12(8), 1256; https://doi.org/10.3390/genes12081256
Available online: https://doi.org/10.3390/genes12081256

10. “The Critical Role of miRNAs in Regulation of Flowering Time and Flower Development”
by Saquib Waheed and Lihui Zeng
Genes 2020, 11(3), 319; https://doi.org/10.3390/genes11030319
Available online: https://doi.org/10.3390/genes11030319

We are pleased to announce that the website of the MDPI Sustainability Foundation has been revamped! For the past couple of months, our UX UI team and front-end developers have been working hard to launch the website in time for the opening of the Sustainability Awards nominations.

The website is not the only thing that has had a remodeling. Indeed, the format of the Emerging Sustainability Leader Award (ESLA) has been updated. ESLA is now a competition open to individual researchers or start-ups founded by researchers under the age of 35. Nominee applications will go through 2 rounds of selection until the final 3 are decided. The finalists will then be invited to give pitch presentations during the Award Ceremony to win either first place (10,000 USD) or runner-up (2 x 5000 USD).

The World Sustainability Award, on the other hand, remains the same: a total prize money of 100,000 USD is up for grabs by senior individual researchers or groups of researchers from the international research community.

Nominations for both the World Sustainability Award and the Emerging Sustainability Leader award are now open! Check out our new website for more information on how to nominate.

1. “Clustered DNA Double-Strand Breaks: Biological Effects and Relevance to Cancer Radiotherapy”
by Jac A. Nickoloff, Neelam Sharma and Lynn Taylor
Genes 2020, 11(1), 99; https://doi.org/10.3390/genes11010099
Full text available online: https://www.mdpi.com/2073-4425/11/1/99

2. “Protein Coding and Long Noncoding RNA (lncRNA) Transcriptional Landscape in SARS-CoV-2 Infected Bronchial Epithelial Cells Highlight a Role for Interferon and Inflammatory Response”
by Radhakrishnan Vishnubalaji, Hibah Shaath and Nehad M. Alajez
Genes 2020, 11(7), 760; https://doi.org/10.3390/genes11070760
Full text available online: https://www.mdpi.com/2073-4425/11/7/760

3. “Prediction and Analysis of SARS-CoV-2-Targeting MicroRNA in Human Lung Epithelium”
by Jonathan Tak-Sum Chow and Leonardo Salmena
Genes 2020, 11(9), 1002; https://doi.org/10.3390/genes11091002
Full text available online: https://www.mdpi.com/2073-4425/11/9/1002

4. “Replication Stress, DNA Damage, Inflammatory Cytokines and Innate Immune Response”
by Sandrine Ragu, Gabriel Matos-Rodrigues and Bernard S. Lopez
Genes 2020, 11(4), 409; https://doi.org/10.3390/genes11040409
Full text available online: https://www.mdpi.com/2073-4425/11/4/409

5. “Circulatory miR-133b and miR-21 as Novel Biomarkers in Early Prediction and Diagnosis of Coronary Artery Disease”
by Dinesh Kumar, Rajiv Narang, Vishnubhatla Sreenivas, Vandana Rastogi, Jagriti Bhatia, Daman Saluja and Kamna Srivastava
Genes 2020, 11(2), 164; https://doi.org/10.3390/genes11020164
Full text available online: https://www.mdpi.com/2073-4425/11/2/164

6. “DNA Replication Stress and Chromosomal Instability: Dangerous Liaisons”
by Therese Wilhelm, Maha Said and Valeria Naim
Genes 2020, 11(6), 642; https://doi.org/10.3390/genes11060642
Full text available online: https://www.mdpi.com/2073-4425/11/6/642

7. “HMGA2 as a Critical Regulator in Cancer Development”
by Behzad Mansoori, Ali Mohammadi, Henrik J. Ditzel, Pascal H. G. Duijf, Vahid Khaze, Morten F. Gjerstorff and Behzad Baradaran
Genes 2021, 12(2), 269; https://doi.org/10.3390/genes12020269
Full text available online: https://www.mdpi.com/2073-4425/12/2/269

8. “Inhibition of Angiotensin-Converting Enzyme Ameliorates Renal Fibrosis by Mitigating DPP-4 Level and Restoring Antifibrotic MicroRNAs”
by Swayam Prakash Srivastava, Julie E. Goodwin, Keizo Kanasaki and Daisuke Koya
Genes 2020, 11(2), 211; https://doi.org/10.3390/genes11020211
Full text available online: https://www.mdpi.com/2073-4425/11/2/211

9. “Analysis of RNA Modifications by Second- and Third-Generation Deep Sequencing: 2020 Update”
by Yuri Motorin and Virginie Marchand
Genes 2021, 12(2), 278; https://doi.org/10.3390/genes12020278
Full text available online: https://www.mdpi.com/2073-4425/12/2/278

10. “History of DNA Helicases”
by Robert M. Brosh, Jr. and Steven W. Matson
Genes 2020, 11(3), 255; https://doi.org/10.3390/genes11030255
Full text available online: https://www.mdpi.com/2073-4425/11/3/255