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Most Cited

  • Review
  • Open Access
305 Citations
42,140 Views
20 Pages

9 January 2023

Plant genetic resources (PGRs) are the total hereditary material, which includes all the alleles of various genes, present in a crop species and its wild relatives. They are a major resource that humans depend on to increase farming resilience and pr...

  • Review
  • Open Access
160 Citations
19,286 Views
18 Pages

miRNAs: Potential as Biomarkers and Therapeutic Targets for Cancer

  • Atonu Chakrabortty,
  • Daniel J. Patton,
  • Bruce F. Smith and
  • Payal Agarwal

29 June 2023

MicroRNAs (miRNAs) are single-stranded, non-coding RNA molecules that regulate gene expression post-transcriptionally by binding to messenger RNAs. miRNAs are important regulators of gene expression, and their dysregulation is implicated in many huma...

  • Review
  • Open Access
127 Citations
15,439 Views
36 Pages

Multi-Omics Pipeline and Omics-Integration Approach to Decipher Plant’s Abiotic Stress Tolerance Responses

  • Rajib Roychowdhury,
  • Soumya Prakash Das,
  • Amber Gupta,
  • Parul Parihar,
  • Kottakota Chandrasekhar,
  • Umakanta Sarker,
  • Ajay Kumar,
  • Devade Pandurang Ramrao and
  • Chinta Sudhakar

16 June 2023

The present day’s ongoing global warming and climate change adversely affect plants through imposing environmental (abiotic) stresses and disease pressure. The major abiotic factors such as drought, heat, cold, salinity, etc., hamper a plant&rs...

  • Review
  • Open Access
123 Citations
34,127 Views
21 Pages

9 March 2023

Autism spectrum disorder (ASD) consists of a group of heterogeneous genetic neurobehavioral disorders associated with developmental impairments in social communication skills and stereotypic, rigid or repetitive behaviors. We review common behavioral...

  • Review
  • Open Access
121 Citations
36,682 Views
21 Pages

Real-Time Polymerase Chain Reaction: Current Techniques, Applications, and Role in COVID-19 Diagnosis

  • I Made Artika,
  • Yora Permata Dewi,
  • Ita Margaretha Nainggolan,
  • Josephine Elizabeth Siregar and
  • Ungke Antonjaya

16 December 2022

Successful detection of the first SARS-CoV-2 cases using the real-time polymerase chain reaction (real-time PCR) method reflects the power and usefulness of this technique. Real-time PCR is a variation of the PCR assay to allow monitoring of the PCR...

  • Review
  • Open Access
108 Citations
21,046 Views
42 Pages

The Hexosamine Biosynthesis Pathway: Regulation and Function

  • Alysta Paneque,
  • Harvey Fortus,
  • Julia Zheng,
  • Guy Werlen and
  • Estela Jacinto

18 April 2023

The hexosamine biosynthesis pathway (HBP) produces uridine diphosphate-N-acetyl glucosamine, UDP-GlcNAc, which is a key metabolite that is used for N- or O-linked glycosylation, a co- or post-translational modification, respectively, that modulates p...

  • Review
  • Open Access
83 Citations
13,253 Views
23 Pages

Genetic and Epigenetic Etiology of Inflammatory Bowel Disease: An Update

  • Sara Jarmakiewicz-Czaja,
  • Magdalena Zielińska,
  • Aneta Sokal and
  • Rafał Filip

16 December 2022

Inflammatory bowel disease (IBD) is a chronic disease with periods of exacerbation and remission of the disease. The etiology of IBD is not fully understood. Many studies point to the presence of genetic, immunological, environmental, and microbiolog...

  • Review
  • Open Access
83 Citations
32,061 Views
23 Pages

Impact of Advanced Paternal Age on Fertility and Risks of Genetic Disorders in Offspring

  • Aris Kaltsas,
  • Efthalia Moustakli,
  • Athanasios Zikopoulos,
  • Ioannis Georgiou,
  • Fotios Dimitriadis,
  • Evangelos N. Symeonidis,
  • Eleftheria Markou,
  • Theologos M. Michaelidis,
  • Dung Mai Ba Tien and
  • Ioannis Giannakis
  • + 6 authors

14 February 2023

The average age of fathers at first pregnancy has risen significantly over the last decade owing to various variables, including a longer life expectancy, more access to contraception, later marriage, and other factors. As has been proven in several...

  • Review
  • Open Access
81 Citations
36,546 Views
32 Pages

Genes and Athletic Performance: The 2023 Update

  • Ekaterina A. Semenova,
  • Elliott C. R. Hall and
  • Ildus I. Ahmetov

8 June 2023

Phenotypes of athletic performance and exercise capacity are complex traits influenced by both genetic and environmental factors. This update on the panel of genetic markers (DNA polymorphisms) associated with athlete status summarises recent advance...

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Genes - ISSN 2073-4425Creative Common CC BY license