Announcements

7 March 2023
Displaying Co-Authors’ Email Addresses on the Webpage of Published Papers

MDPI is pleased to announce that we now display the co-authors’ email addresses in addition to the corresponding author’s email address on the webpage of published papers, protected by Captcha. For more information about this change, please visit the journal’s instructions for authors page. 

We believe this change will facilitate academic discussions and advance our cause of open science and research. The corresponding authors are responsible for communicating with their co-authors and indicating in our system (https://susy.mdpi.com/) if co-authors would prefer for their email addresses not to be displayed.

23 February 2023
Genes | Editor’s Choice Articles


The Editor’s Choice Articles are based on recommendations by the scientific editors of MDPI journals from around the world. Editors select a small number of articles that have recently been published in the journal that they believe will be particularly interesting to authors, or important in this field. The aim is to provide a snapshot of some of the most exciting work published in the various research areas of the journal.

We are pleased to present the Editor’s Choice Articles published in Genes (ISSN: 2073-4425), and we hope that these papers can help and provide a reference for your academic research. A carefully curated list of high-quality articles can be found below.

1. “Regulation of Ergosterol Biosynthesis in Saccharomyces cerevisiae
by Tania Jordá and Sergi Puig
Genes 2020, 11(7), 795; https://doi.org/10.3390/genes11070795
Available online: https://www.mdpi.com/2073-4425/11/7/795

2. “Histone Deacetylases (HDACs): Evolution, Specificity, Role in Transcriptional Complexes, and Pharmacological Actionability”
by Giorgio Milazzo, Daniele Mercatelli, Giulia Di Muzio, Luca Triboli, Piergiuseppe De Rosa, Giovanni Perini and Federico M. Giorgi
Genes 2020, 11(5), 556; https://doi.org/10.3390/genes11050556
Available online: https://www.mdpi.com/2073-4425/11/5/556

3. “Knee Osteoarthritis: A Review of Pathogenesis and State-Of-The-Art Non-Operative Therapeutic Considerations”
by Dragan Primorac, Vilim Molnar, Eduard Rod, Željko Jeleč, Fabijan Čukelj, Vid Matišić, Trpimir Vrdoljak, Damir Hudetz, Hana Hajsok and Igor Borić
Genes 2020, 11(8), 854; https://doi.org/10.3390/genes11080854
Available online: https://www.mdpi.com/2073-4425/11/8/854

4. “Genomics in Bacterial Taxonomy: Impact on the Genus Pseudomonas
by Jorge Lalucat, Magdalena Mulet, Margarita Gomila and Elena García-Valdés
Genes 2020, 11(2), 139; https://doi.org/10.3390/genes11020139
Available online: https://www.mdpi.com/2073-4425/11/2/139

5. “Clustered DNA Double-Strand Breaks: Biological Effects and Relevance to Cancer Radiotherapy”
by Jac A. Nickoloff, Neelam Sharma and Lynn Taylor
Genes 2020, 11(1), 99; https://doi.org/10.3390/genes11010099
Available online: https://www.mdpi.com/2073-4425/11/1/99

6. “The Changing Epidemiology of Cystic Fibrosis: Incidence, Survival and Impact of the CFTR Gene Discovery”
by Virginie Scotet, Carine L’Hostis and Claude Férec
Genes 2020, 11(6), 589; https://doi.org/10.3390/genes11060589
Available online: https://www.mdpi.com/2073-4425/11/6/589

7. “COVID-19 and Genetic Variants of Protein Involved in the SARS-CoV-2 Entry into the Host Cells”
by Andrea Latini, Emanuele Agolini, Antonio Novelli, Paola Borgiani, Rosalinda Giannini, Paolo Gravina, Andrea Smarrazzo, Mario Dauri, Massimo Andreoni, Paola Rogliani et al.
Genes 2020, 11(9), 1010; https://doi.org/10.3390/genes11091010
Available online: https://www.mdpi.com/2073-4425/11/9/1010

8. “Transcriptional Factors Regulate Plant Stress Responses Through Mediating Secondary Metabolism”
by Tehseen Ahmad Meraj, Jingye Fu, Muhammad Ali Raza, Chenying Zhu, Qinqin Shen, Dongbei Xu and Qiang Wang
Genes 2020, 11(4), 346; https://doi.org/10.3390/genes11040346
Available online: https://www.mdpi.com/2073-4425/11/4/346

9. “Protein Coding and Long Noncoding RNA (lncRNA) Transcriptional Landscape in SARS-CoV-2 Infected Bronchial Epithelial Cells Highlight a Role for Interferon and Inflammatory Response”
by Radhakrishnan Vishnubalaji, Hibah Shaath and Nehad M. Alajez
Genes 2020, 11(7), 760; https://doi.org/10.3390/genes11070760
Available online: https://www.mdpi.com/2073-4425/11/7/760

10. “Regulation of mTORC2 Signaling”
by Wenxiang Fu and Michael N. Hall
Genes 2020, 11(9), 1045; https://doi.org/10.3390/genes11091045
Available online: https://www.mdpi.com/2073-4425/11/9/1045

11. “A Review of the Important Role of CYP2D6 in Pharmacogenomics”
by Christopher Taylor, Ian Crosby, Vincent Yip, Peter Maguire, Munir Pirmohamed and Richard M. Turner
Genes 2020, 11(11), 1295; https://doi.org/10.3390/genes11111295
Available online: https://www.mdpi.com/2073-4425/11/11/1295

12. “Down Regulation and Loss of Auxin Response Factor 4 Function Using CRISPR/Cas9 Alters Plant Growth, Stomatal Function and Improves Tomato Tolerance to Salinity and Osmotic Stress”
by Sarah Bouzroud, Karla Gasparini, Guojian Hu, Maria Antonia Machado Barbosa, Bruno Luan Rosa, Mouna Fahr, Najib Bendaou, Mondher Bouzayen, Agustin Zsögön, Abdelaziz Smouni et al.
Genes 2020, 11(3), 272; https://doi.org/10.3390/genes11030272
Available online: https://www.mdpi.com/2073-4425/11/3/272

13. “Mutation Patterns of Human SARS-CoV-2 and Bat RaTG13 Coronavirus Genomes Are Strongly Biased Towards C>U Transitions, Indicating Rapid Evolution in Their Hosts”
by Roman Matyášek and Aleš Kovařík
Genes 2020, 11(7), 761; https://doi.org/10.3390/genes11070761
Available online: https://www.mdpi.com/2073-4425/11/7/761

14. “Prediction and Analysis of SARS-CoV-2-Targeting MicroRNA in Human Lung Epithelium”
by Jonathan Tak-Sum Chow and Leonardo Salmena
Genes 2020, 11(9), 1002; https://doi.org/10.3390/genes11091002
Available online: https://www.mdpi.com/2073-4425/11/9/1002

15. “A Novel Cuproptosis-Related Prognostic Gene Signature and Validation of Differential Expression in Clear Cell Renal Cell Carcinoma”
by Zilong Bian, Rong Fan and Lingmin Xie
Genes 2022, 13(5), 851; https://doi.org/10.3390/genes13050851
Available online: https://www.mdpi.com/2073-4425/13/5/851

16. “Plasmid Transfer by Conjugation in Gram-Negative Bacteria: From the Cellular to the Community Level”
by Chloé Virolle, Kelly Goldlust, Sarah Djermoun, Sarah Bigot and Christian Lesterlin
Genes 2020, 11(11), 1239; https://doi.org/10.3390/genes11111239
Available online: https://www.mdpi.com/2073-4425/11/11/1239

17. “Efficient Generation and Correction of Mutations in Human iPS Cells Utilizing mRNAs of CRISPR Base Editors and Prime Editors”
by Duran Sürün, Aksana Schneider, Jovan Mircetic, Katrin Neumann, Felix Lansing, Maciej Paszkowski-Rogacz, Vanessa Hänchen, Min Ae Lee-Kirsch and Frank Buchholz
Genes 2020, 11(5), 511; https://doi.org/10.3390/genes11050511
Available online: https://www.mdpi.com/2073-4425/11/5/511

18. “Genetic Modifiers and Rare Mendelian Disease”
by K. M. Tahsin Hassan Rahit and Maja Tarailo-Graovac
Genes 2020, 11(3), 239; https://doi.org/10.3390/genes11030239
Available online: https://www.mdpi.com/2073-4425/11/3/239

19. “Mechanisms of Photoreceptor Death in Retinitis Pigmentosa”
by Fay Newton and Roly Megaw
Genes 2020, 11(10), 1120; https://doi.org/10.3390/genes11101120
Available online: https://www.mdpi.com/2073-4425/11/10/1120

20. “The AP2/ERF Gene Family in Triticum durum: Genome-Wide Identification and Expression Analysis under Drought and Salinity Stresses”
by Sahar Faraji, Ertugrul Filiz, Seyed Kamal Kazemitabar, Alessandro Vannozzi, Fabio Palumbo, Gianni Barcaccia and Parviz Heidari
Genes 2020, 11(12), 1464; https://doi.org/10.3390/genes11121464
Available online: https://www.mdpi.com/2073-4425/11/12/1464

We would like to take this opportunity to thank all of the research groups that submitted manuscripts to Genes. We would appreciate it if you could circulate this document among your colleagues and network. Furthermore, the following opportunities for collaboration may be of interest:

Submitting a Manuscript:
Genes is an open access journal that publishes spotlights, reviews, original research contributions, and short communications. Papers may be submitted via the following link:
https://susy.mdpi.com/user/manuscripts/upload/?journal=genes.

Launching a Special Issue:
You have the opportunity to propose hot topics and edit a Special Issue together with experts in the field. More information can be found at the following link:
https://www.mdpi.com/journalproposal/sendproposalspecialissue/genes.

Joining the Editorial Board:
If you are an active researcher in the field of genetics and are interested in joining the Editorial Board, please do not hesitate to get in touch (genes@mdpi.com).

16 February 2023
Increasing Visibility for Preprints.org – Clarivate adds the Preprint Citation Index to the Web of Science

On 9 February 2023, Clarivate, a global leader in providing trusted insights and analytics, added the Preprint Citation Index to the Web of Science platform, streamlining the research process by allowing researchers to locate and link to preprints alongside other trusted content in the database.

The Preprint Citation Index will act as a bridge to connect cutting-edge preprints with peer-reviewed journal articles published within the Web of Science Core Collection. Alerts can be easily set to monitor new research across several repositories and authors will also be able to include preprints on their Web of Science Research Profile to more accurately display their various research outputs.

As of its launch, the Preprint Citation Index will provide nearly two million preprints from various repositories, including MDPI’s own Preprints.org.

MDPI's Preprints Platform – Preprints.org

To advance Open Science and the fast dissemination of research, MDPI offers researchers a free multidisciplinary preprint platform. Preprints.org accepts submissions from all research areas and offers authors high visibility, permanent archiving, article-level Metrics and immediately citable content by assigning a Digital Object Identifier (DOI) to all preprints.

During submission to any MDPI journal, authors have the option to share their research as a preprint. After an initial screening, the manuscript is available online in 48 hours or less. Once online, preprints can be downloaded, shared, commented on, and cited, providing authors maximum visibility.

We invite you to join the ranks of the over 100k researchers using Preprints.org and share your research.

For more information, please visit Preprints.org.

14 February 2023
Meet Us at the 11th National Conference on Bioinformatics and Systems Biology, 25–27 February 2023, Guangzhou, China


Conference
: 11th National Conference on Bioinformatics and Systems Biology
Date: 25–27 February 2023
Place: Guangzhou, China

MDPI will be attending the 11th National Conference on Bioinformatics and Systems Biology (CCBSB2023) as the exhibitor. The National Academic Conference on Bioinformatics and Systems Biology has been successfully held for ten sessions since its first session in 1998. It is a national event with the highest academic level and the greatest influence in the field of bioinformatics research in China. The theme of the conference is "The Latest Frontier Research of Bioinformatics and Systems Biology and Their Applications", and the topics cover translational informatics and data sharing security, biomedical data mining and computing, genome informatics, artificial intelligence and life sciences, group bioinformatics and integrated biology, non-coding RNA and RNA informatics, network biology, major disease omics informatics, biological macromolecular structure prediction and simulation, bioinformatics algorithm research, biological data resources, bioinformatics and drugs discovery, computational synthetic biology, agricultural and forestry informatics and other bioinformatics, and other frontier directions.

The following MDPI journals will be represented:

If you are attending this conference, please feel free to start a conversation with us. Our delegates look forward to meeting you in person and answering any questions that you may have. For more information about the conference, please visit https://ccbsb2022.casconf.cn/.

9 February 2023
Media Partnership between Genes and the 34th Meeting of the Developmental Biology Section of the Catalan Society of Biology


We are pleased to announce that the 34th meeting of the Developmental Biology Section of the Catalan Society of Biology has set up a free media partnership with Genes (ISSN: 2073-4425). The conference will provide ample opportunities for networking both professionally and socially.

Conference date: 10 Feb 2023
Place: Sala Prat de la Riba, IEC, Spain

This conference brings together the community working in the field of developmental biology. Researchers from different institutions will have the opportunity to spend the day together presenting their results and discussing the latest findings in the field. This meeting is organized by Marta Llimargas (IBMB-CSIC), Barbara Pernaute (CRG), Esteban Hoijman (UB-IDIBELL), Manuel Irimia (CRG) and Marta Morey (UB-IBUB).

For more details, please visit the following link: https://scb.iec.cat/xxxiv-jornada-de-biologia-del-desenvolupament/.

Genes Editorial Office

22 December 2022
Special Issue Mentor Program

We are pleased to announce the launch of a new initiative—the MDPI Special Issue Mentor Program.

This program will enable early career researchers (who must hold a Ph.D. in a related field) to experience editing a Special Issue in MDPI journals, under the mentorship of our experienced Editorial Board Members or other experienced scientists. The mentor program will provide an excellent opportunity for early career scientists to gain editorial experience, and to cultivate their ability to edit scientific research.

The mentee’s responsibilities include:

  • Proposing a Special Issue title and assisting the mentor in preparing a summary (around 200–400 words) and 3–10 keywords describing the background, importance, and goal of the Issue;
  • Writing a brief promotion plan for the Special Issue;
  • Preparing a list of scholars who may be interested in the Issue and personally e-mailing invitations on behalf of Guest Editors;
  • Writing an editorial for the online Special Issue together with the mentor.

The mentor’s responsibilities include:

  • Conducting a final check before the Special Issue is published online;
  • Performing editorial control of the Special Issue and quality control of the publications, both of which must be carried out in a timely manner;
  • Providing suggestions to younger scholars if they have any doubts or concerns regarding submissions;
  • Organizing video calls with young scholars and the Editorial Office regularly to discuss problems and improvement suggestions for the Special Issue;
  • Making and submitting decisions regarding submissions with the assistance of mentees.

Certificates and awards:
After the Special Issue closes, the Editorial Office will provide official certificates for all the mentors and early career researchers.

If you are interested in this opportunity, please send your Special Issue proposal to the Editorial Office of a journal you choose, and we will discuss the process (i.e., mentor collaboration, Special Issue topic feasibility analysis, etc.) in further detail. The full list of MDPI journals is as follows: https://www.mdpi.com/about/journals.

In addition to the new Special Issue Mentor Program, we will continue to welcome all Special Issue proposals focusing on hot research topics.

22 December 2022
Genes | Top 10 Cited Papers in 2021 in the Section “Bioinformatics”


1. “Detection of A-to-I RNA Editing in SARS-COV-2”
by Ernesto Picardi, Luigi Mansi and Graziano Pesole
Genes 2022, 13(1), 41; https://doi.org/10.3390/genes13010041
Full text available online: https://www.mdpi.com/2073-4425/13/1/41

2. “Pyroptosis Patterns Characterized by Distinct Tumor Microenvironment Infiltration Landscapes in Gastric Cancer”
by Renshen Xiang, Yuhang Ge, Wei Song, Jun Ren, Can Kong and Tao Fu
Genes 2021, 12(10), 1535; https://doi.org/10.3390/genes12101535
Full text available online: https://www.mdpi.com/2073-4425/12/10/1535

3. “Machine Learning and Bioinformatics Framework Integration to Potential Familial DCM-Related Markers Discovery”
by Concetta Schiano, Monica Franzese, Filippo Geraci, Mario Zanfardino, Ciro Maiello, Vittorio Palmieri, Andrea Soricelli, Vincenzo Grimaldi, Enrico Coscioni, Marco Salvatore et al.
Genes 2021, 12(12), 1946; https://doi.org/10.3390/genes12121946
Full text available online: https://www.mdpi.com/2073-4425/12/12/1946

4. “PlantMirP2: An Accurate, Fast and Easy-To-Use Program for Plant Pre-miRNA and miRNA Prediction”
by Dashuai Fan, Yuangen Yao and Ming Yi
Genes 2021, 12(8), 1280; https://doi.org/10.3390/genes12081280
Full text available online: https://www.mdpi.com/2073-4425/12/8/1280

5. “Integrated Bioinformatics Analysis Reveals Marker Genes and Potential Therapeutic Targets for Pulmonary Arterial Hypertension”
by Aoqi Li, Jin He, Zhe Zhang, Sibo Jiang, Yun Gao, Yuchun Pan, Huanan Wang and Lenan Zhuang
Genes 2021, 12(9), 1339; https://doi.org/10.3390/genes12091339
Full text available online: https://www.mdpi.com/2073-4425/12/9/1339

6. “Analysis of Codon Usage Patterns of Six Sequenced Brachypodium distachyon Lines Reveals a Declining CG Skew of the CDSs from the 5′-ends to the 3′-ends”
by Jianyong Wang, Yujing Lin and Mengli Xi
Genes 2021, 12(10), 1467; https://doi.org/10.3390/genes12101467
Full text available online: https://www.mdpi.com/2073-4425/12/10/1467

7. “Attention-Based Deep Multiple-Instance Learning for Classifying Circular RNA and Other Long Non-Coding RNA”
by Yunhe Liu, Qiqing Fu, Xueqing Peng, Chaoyu Zhu, Gang Liu and Lei Liu
Genes 2021, 12(12), 2018; https://doi.org/10.3390/genes12122018
Full text available online: https://www.mdpi.com/2073-4425/12/12/2018

8. “Characterizing HIV-1 Genetic Subtypes and Drug Resistance Mutations among Children, Adolescents and Pregnant Women in Sierra Leone”
by George A. Yendewa, Sulaiman Lakoh, Sahr A. Yendewa, Khadijah Bangura, Andrés Tabernilla, Lucia Patiño, Darlinda F. Jiba, Alren O. Vandy, Samuel P. Massaquoi, Nuno S. Osório et al.
Genes 2021, 12(9), 1314; https://doi.org/10.3390/genes12091314
Full text available online: https://www.mdpi.com/2073-4425/12/9/1314

9. “Tandem Mass Tag-Based Quantitative Proteomic Analysis of ISG15 Knockout PK15 Cells in Pseudorabies Virus Infection”
by Wenfeng He, Chen Li, Liangliang Dong, Guoqing Yang and Huimin Liu
Genes 2021, 12(10), 1557; https://doi.org/10.3390/genes12101557
Full text available online: https://www.mdpi.com/2073-4425/12/10/1557

10. “Cell Differentiation Trajectory-Associated Molecular Classification of Osteosarcoma”
by Ankai Xu, Chao Qian, Jinti Lin, Wei Yu, Jiakang Jin, Bing Liu and Huimin Tao
Genes 2021, 12(11), 1685; https://doi.org/10.3390/genes12111685
Full text available online: https://www.mdpi.com/2073-4425/12/11/1685

22 December 2022
Genes | Top 10 Cited Papers in 2020–2021 in the Section “Animal Genetics and Genomics”


1. “Single-Step Genomic Evaluations from Theory to Practice: Using SNP Chips and Sequence Data in BLUPF90”
by Daniela Lourenco, Andres Legarra, Shogo Tsuruta, Yutaka Masuda, Ignacio Aguilar and Ignacy Misztal
Genes 2020, 11(7), 790; https://doi.org/10.3390/genes11070790
Available online: https://www.mdpi.com/2073-4425/11/7/790

2. “Turtle Insights into the Evolution of the Reptilian Karyotype and the Genomic Architecture of Sex Determination”
by Basanta Bista and Nicole Valenzuela
Genes 2020, 11(4), 416; https://doi.org/10.3390/genes11040416
Available online: https://www.mdpi.com/2073-4425/11/4/416

3. “Decoding the Role of Satellite DNA in Genome Architecture and Plasticity—An Evolutionary and Clinical Affair”
by Sandra Louzada, Mariana Lopes, Daniela Ferreira, Filomena Adega, Ana Escudeiro, Margarida Gama-Carvalho and Raquel Chaves
Genes 2020, 11(1), 72; https://doi.org/10.3390/genes11010072
Available online: https://www.mdpi.com/2073-4425/11/1/72

4. “Eicosanoid Signaling in Insect Immunology: New Genes and Unresolved Issues”
by Yonggyun Kim and David Stanley
Genes 2021, 12(2), 211; https://doi.org/10.3390/genes12020211
Available online: https://www.mdpi.com/2073-4425/12/2/211

5. “A Gene-Set Enrichment and Protein–Protein Interaction Network-Based GWAS with Regulatory SNPs Identifies Candidate Genes and Pathways Associated with Carcass Traits in Hanwoo Cattle”
by Krishnamoorthy Srikanth, Seung-Hwan Lee, Ki-Yong Chung, Jong-Eun Park, Gul-Won Jang, Mi-Rim Park, Na Yeon Kim, Tae-Hun Kim, Han-Ha Chai, Won Cheoul Park et al.
Genes 2020, 11(3), 316; https://doi.org/10.3390/genes11030316
Available online: https://www.mdpi.com/2073-4425/11/3/316

6. “Microfluidic Quantitative PCR Detection of 12 Transgenes from Horse Plasma for Gene Doping Control”
by Teruaki Tozaki, Aoi Ohnuma, Mio Kikuchi, Taichiro Ishige, Hironaga Kakoi, Kei-ichi Hirota, Kanichi Kusano and Shun-ichi Nagata
Genes 2020, 11(4), 457; https://doi.org/10.3390/genes11040457
Available online: https://www.mdpi.com/2073-4425/11/4/457

7. “Comprehensive Analysis of Differentially Expressed Profiles of mRNA, lncRNA, and circRNA in the Uterus of Seasonal Reproduction Sheep”
by Yongfu La, Xiaoyun He, Liping Zhang, Ran Di, Xiangyu Wang, Shangquan Gan, Xiaosheng Zhang, Jinlong Zhang, Wenping Hu and Mingxing Chu
Genes 2020, 11(3), 301; https://doi.org/10.3390/genes11030301
Available online: https://www.mdpi.com/2073-4425/11/3/301

8. “Comparative Transcriptome Analysis Suggests Key Roles for 5-Hydroxytryptamlne Receptors in Control of Goose Egg Production”
by Qingyuan Ouyang, Shenqiang Hu, Guosong Wang, Jiwei Hu, Jiaman Zhang, Liang Li, Bo Hu, Hua He, Hehe Liu, Lu Xia et al.
Genes 2020, 11(4), 455; https://doi.org/10.3390/genes11040455
Available online: https://www.mdpi.com/2073-4425/11/4/455

9. “Exploring the lncRNAs Related to Skeletal Muscle Fiber Types and Meat Quality Traits in Pigs”
by Rongyang Li, Bojiang Li, Aiwen Jiang, Yan Cao, Liming Hou, Zengkai Zhang, Xiying Zhang, Honglin Liu, Kee-Hong Kim and Wangjun Wu
Genes 2020, 11(8), 883; https://doi.org/10.3390/genes11080883
Available online: https://www.mdpi.com/2073-4425/11/8/883

10. “Genomic Identification, Evolution and Sequence Analysis of the Heat-Shock Protein Gene Family in Buffalo”
by Saif ur Rehman, Asif Nadeem, Maryam Javed, Faiz-ul Hassan, Xier Luo, Ruqayya Bint Khalid
and Qingyou Liu
Genes 2020, 11(11), 1388; https://doi.org/10.3390/genes11111388
Available online: https://www.mdpi.com/2073-4425/11/11/1388 

16 December 2022
Genes | Top 10 Cited Papers in 2021 in the Section “Epigenomics”


1. “Altered Expression of DAAM1 and PREP Induced by Cadmium Toxicity Is Counteracted by Melatonin in the Rat Testis”
by Massimo Venditti, Mariem Ben Rhouma, Maria Zelinda Romano, Imed Messaoudi, Russel J. Reiter and Sergio Minucci
Genes 2021, 12(7), 1016; https://doi.org/10.3390/genes12071016
Full text available online: https://www.mdpi.com/2073-4425/12/7/1016

2. “Genetics and Epigenetics in Allergic Rhinitis”
by Choi, Bo Yoon, Munsoo Han, Ji Won Kwak and Tae Hoon Kim
Genes 2021, 12(12), 2004; https://doi.org/10.3390/genes12122004
Full text available online: https://www.mdpi.com/2073-4425/12/12/2004

3. “LINCking the Nuclear Envelope to Sperm Architecture”
by Francesco Manfrevola, Florian Guillou, Silvia Fasano, Riccardo Pierantoni and Rosanna Chianese
Genes 2021, 12(5), 658; https://doi.org/10.3390/genes12050658
Full text available online: https://www.mdpi.com/2073-4425/12/5/658

4. “Evolution of Reproductive Life History in Mammals and the Associated Change of Functional Constraints”
by Jiaqi Wu, Takahiro Yonezawa and Hirohisa Kishino
Genes 2021, 12(5), 740; https://doi.org/10.3390/genes12050740
Full text available online: https://www.mdpi.com/2073-4425/12/5/740

5. “Pediatric and Adolescent Oncofertility in Male Patients—From Alpha to Omega”
by Ovidiu Bîcă, Ioan Sârbu and Carmen Iulia Ciongradi
Genes 2021, 12(5), 701; https://doi.org/10.3390/genes12050701
Full text available online: https://www.mdpi.com/2073-4425/12/5/701

6. “Methylation of Host Genes Associated with Coronavirus Infection from Birth to 26 Years”
by Rutu Rathod, Aniruddha Rathod, Parnian Kheirkhah Rahimabad, Jiasong Duan, Hongmei Zhang, S. Hasan Arshad and Wilfried Karmaus
Genes 2021, 12(8), 1198; https://doi.org/10.3390/genes12081198
Full text available online: https://www.mdpi.com/2073-4425/12/8/1198

7. “Prospects in Connecting Genetic Variation to Variation in Fertility in Male Bees”
by Garett P. Slater, Nicholas M. A. Smith and Brock A. Harpur
Genes 2021, 12(8), 1251; https://doi.org/10.3390/genes12081251
Full text available online: https://www.mdpi.com/2073-4425/12/8/1251

8. “Identification of Long Non-Coding RNAs Involved in Porcine Fat Deposition Using Two High-Throughput Sequencing Methods”
by Yibing Liu, Ying Yu, Hong Ao, Fengxia Zhang, Xitong Zhao, Huatao Liu, Yong Shi, Kai Xing and Chuduan Wang
Genes 2021, 12(9), 1374; https://doi.org/10.3390/genes12091374
Full text available online: https://www.mdpi.com/2073-4425/12/9/1374

9. “Epigenetic Regulation of CDH1 Is Altered after HOXB7-Silencing in MDA-MB-468 Triple-Negative Breast Cancer Cells”
by Ana Paço, Joana Leitão-Castro and Renata Freitas
Genes 2021, 12(10), 1575; https://doi.org/10.3390/genes12101575
Full text available online: https://www.mdpi.com/2073-4425/12/10/1575

10. “Aberrant DNA Methylation Mediates the Transgenerational Risk of Metabolic and Chronic Disease Due to Maternal Obesity and Overnutrition”
by Yan Li, Carol A. Pollock and Sonia Saad
Genes 2021, 12(11), 1653; https://doi.org/10.3390/genes12111653
Full text available online: https://www.mdpi.com/2073-4425/12/11/1653

15 December 2022
Genes | Top 10 Cited Papers in 2020–2021 in the Section “Human Genomics and Genetic Diseases”


1. “The Changing Epidemiology of Cystic Fibrosis: Incidence, Survival and Impact of the CFTR Gene Discovery”
by Virginie Scotet, Carine L’Hostis and Claude Férec
Genes 2020, 11(6), 589; https://doi.org/10.3390/genes11060589
Full text available online: https://www.mdpi.com/2073-4425/11/6/589

2. “COVID-19 and Genetic Variants of Protein Involved in the SARS-CoV-2 Entry into the Host Cells”
by Andrea Latini, Emanuele Agolini, Antonio Novelli, Paola Borgiani, Rosalinda Giannini, Paolo Gravina, Andrea Smarrazzo, Mario Dauri, Massimo Andreoni, Paola Rogliani et al.
Genes 2020, 11(9), 1010; https://doi.org/10.3390/genes11091010
Full text available online: https://www.mdpi.com/2073-4425/11/9/1010

3. “Regulation of mTORC2 Signaling”     
by Wenxiang Fu and Michael N. Hall
Genes 2020, 11(9), 1045; https://doi.org/10.3390/genes11091045
Full text available online: https://www.mdpi.com/2073-4425/11/9/1045

4. “A Review of the Important Role of CYP2D6 in Pharmacogenomics”
by Christopher Taylor, Ian Crosby, Vincent Yip, Peter Maguire, Munir Pirmohamed and Richard M. Turner
Genes 2020, 11(11), 1295; https://doi.org/10.3390/genes11111295
Full text available online: https://www.mdpi.com/2073-4425/11/11/1295

5. “Mechanisms of Photoreceptor Death in Retinitis Pigmentosa”
by Fay Newton and Roly Megaw
Genes 2020, 11(10), 1120; https://doi.org/10.3390/genes11101120
Full text available online: https://www.mdpi.com/2073-4425/11/10/1120

6. “Therapeutic Strategies for Duchenne Muscular Dystrophy: An Update”
by Chengmei Sun, Luoan Shen, Zheng Zhang and Xin Xie
Genes 2020, 11(8), 837; https://doi.org/10.3390/genes11080837
Full text available online: https://www.mdpi.com/2073-4425/11/8/837

7. “RET Gene Fusions in Malignancies of the Thyroid and Other Tissues”
by Massimo Santoro, Marialuisa Moccia, Giorgia Federico and Francesca Carlomagno
Genes 2020, 11(4), 424; https://doi.org/10.3390/genes11040424
Full text available online: https://www.mdpi.com/2073-4425/11/4/424

8. “The Microbiome in Cystic Fibrosis Pulmonary Disease”
by Alice Françoise and Geneviève Héry-Arnaud
Genes 2020, 11(5), 536; https://doi.org/10.3390/genes11050536
Full text available online: https://www.mdpi.com/2073-4425/11/5/536 

9. “Extracellular Vesicles Derived from Human Gingival Mesenchymal Stem Cells: A Transcriptomic Analysis”
by Serena Silvestro, Luigi Chiricosta, Agnese Gugliandolo, Jacopo Pizzicannella, Francesca Diomede, Placido Bramanti, Oriana Trubiani and Emanuela Mazzon
Genes 2020, 11(2), 118; https://doi.org/10.3390/genes11020118
Full text available online: https://www.mdpi.com/2073-4425/11/2/118

10. “The Roles of the NLRP3 Inflammasome in Neurodegenerative and Metabolic Diseases and in Relevant Advanced Therapeutic Interventions”
by Rameez Hassan Pirzada, Nasir Javaid and Sangdun Choi
Genes 2020, 11(2), 131; https://doi.org/10.3390/genes11020131
Full text available online: https://www.mdpi.com/2073-4425/11/2/131

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