Announcements
4 July 2025
MDPI’s Newly Launched Journals in June 2025
Six new journals covering a range of subjects launched their inaugural issues in June 2025. We are excited to be able to share with you the newest research rooted in the value of open access. We are pleased to present the latest research and to make it accessible to all.
We extend our sincere thanks to all the Editorial Board Members for their commitment and expertise. Each journal is dedicated to upholding strong editorial standards through a thorough peer review process, ensuring impactful open access scholarship.
Please feel free to browse and discover more about the new journals below.
| Journal | Founding Editor-in-Chief | Journal Topics (Selected) |
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Prof. Dr. Chang-Pu Sun, China Academy of Engineering Physics, Beijing, China; Computational Science Research Center, China Editorial | View inaugural issue |
quantum information and phenomena; condensed matter physics and statistical physics; atomic, molecular, and optical physics; computational physics and mathematical methods View journal scope | Submit an article |
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Prof. Dr. Hualiang Lin, Sun Yat-sen University, China; Prof. Dr. Jose L. Domingo, Universitat Rovira i Virgili, Spain Editorial | View inaugural issue |
green and organic food; green infrastructures; green exercise; environmental impact of the healthcare sector; effects of climate change on human health | View journal scope | Submit an article |
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Prof. Dr. Francesco Veglio, University of L’Aquila, Italy Editorial | View inaugural issue |
ultra-pure substances; water purification; air purification; gas purification; inorganic chemical purification; purification technologies View journal scope | Submit an article |
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Prof. Dr. Junxing Zheng, Huazhong University of Science and Technology, China Editorial | View inaugural issue |
computer-aided design and engineering; artificial intelligence and machine learning; building information modeling (BIM) and digital twins; robotics and automation in construction; smart sensors and Internet of Things (IoT); intelligent control systems and facilities management View journal scope | Submit an article |
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Prof. Dr. Assunta Di Vaio, University of Naples Parthenope, Italy Editorial | View inaugural issue |
sustainability, managerial, and biodiversity accounting; carbon management accounting; corporate social responsibility; artificial intelligence and disclosure View journal scope | Submit an article |
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Prof. Dr. Changjun Liu, Sichuan University, China Editorial | View inaugural issue |
bioeffects of electromagnetic waves; electromagnetic science and engineering; microwave, millimeter-wave, and terahertz technologies; metamaterials and metasurfaces; communication, sensing, and networks; energy, power, and sustainable applications; quantum and emerging technologies; artificial intelligence and advanced fabrication View journal scope | Submit an article |
2 July 2025
MDPI INSIGHTS: The CEO's Letter #24 - 2024 Impact Factor & CiteScore, MDPI Summits France & USA, Tu Youyou Award
Welcome to the MDPI Insights: The CEO's Letter.
In these monthly letters, I will showcase two key aspects of our work at MDPI: our commitment to empowering researchers and our determination to facilitating open scientific exchange.
Opening Thoughts
MDPI’s 2024 Impact Factor Highlights
For those of our readers who are new to academic publishing, you may have heard some news in June around the Impact Factor release. Every year, typically in June, Clarivate releases its annual Journal Citation Reports (JCR), which include Journal Impact Factors (JIF). This metric is widely used in academic publishing to reflect the average number of citations received by recent articles in each journal.
While Impact Factor is just one of many indicators of journal influence, it remains a major milestone for authors, editors, and publishers. It’s used to assess journal visibility, researcher recognition, and scholarly reach. Throughout our international meetings and events, it’s clear that the Impact Factor is something many of our authors and editorial board members care about, as it can influence where they choose to submit an article and the funding they receive for their research.
“These results reflect the trust that the scholarly community places in MDPI”
MDPI’s 2024 Impact Factor Highlights
- 298 MDPI journals received a Journal Impact Factor.
- 60 journals earned their first-ever Impact Factor
- To put this in perspective: MDPI’s 60 new journal acceptances into the Web of Science was the second highest number of any publisher in 2024, behind Elsevier and ahead of Springer Nature. Our 87% acceptance rate for journals submitted to Web of Science shows the strength of our editorial process and our proven ability to develop journals aligned with Clarivate’s 24 evaluation criteria.
- Notably, Textiles, Mathematics, International Journal of Neonatal Screening, Smart Cities, Systems, and Pharmaceutics ranked in the top 10% in their respective categories, highlighting their growing influence and prestige within their academic fields. This shows that high-quality indexing goes beyond visibility; it upholds credibility and trust.
- 193 MDPI journals are now ranked in the top 50% (Q1/Q2) of their subject categories.
- What does this mean, and why is it important? Journals are ranked by quartiles within their field, based on their Impact Factor. Q1 represents the top 25% of journals in their category, Q2 the next 25%, and so on. Being in Q1 or Q2 shows that a journal is performing well relative to other journals in its category. Authors and institutions often look at quartile rankings when choosing where to publish – it’s an important indicator of visibility and recognition, within its respective category.
- 116 of our previously ranked journals increased their Impact Factor.
- 14 MDPI journals achieved an Impact Factor of 5.0 or higher, suggesting a high degree of influence and visibility.
These results reflect our staff's hard work: from our editorial and production teams to our indexing, communications, and data teams, and beyond. This also reflects the trust that the scholarly community places in MDPI, reinforcing the message that when researchers publish with MDPI, they publish with impact.
Open Access with Impact
As the leading fully open access publisher, our journals have received a total of 18.4 million citations in the Web of Science by the end of 2024, reflecting the growing reach and engagement of research published with MDPI. We are committed to making scientific research freely accessible to everyone, everywhere. With the support of more than 4.2 million contributing authors, we’re proud to support the global shift toward open access.
Further Reading
If you’d like to better understand how journals get indexed and why Impact Factors matter, please read this recent interview with Dr. Constanze Schelhorn (Head of Indexing). It gives you a behind-the-scenes look at the role our indexing team plays in supporting journal indexing and visibility.
You can also read our official news announcement shared last week: MDPI Journals in the 2024 Journal Citation Reports.
Thank you to everyone, from our authors and reviewers to our editors and internal teams, who contributed to the progress of our journal indexing in 2024. We’re continuing to build journals that are recognized and trusted across disciplines.
Impactful Research
MDPI Journals See Continued Growth in 2024 CiteScore Results
Continuing our indexing updates, I’m pleased to share that MDPI has achieved strong results in the latest CiteScore metrics, released on 5 June by Scopus. These results reflect the collective efforts of our editors, reviewers, authors, and internal teams, with their dedication to quality and visibility in scientific publishing. You can read the full announcement here.
2024 Highlights:
- 322 MDPI journals received a CiteScore (up from 274 last year).
- 283 journals (88%) are ranked in Q1 or Q2 of their subject categories.
- 237 journals (85%) saw an increase in their CiteScore compared to last year.
- 48 journals received a CiteScore for the first time.
- 39 journals are now placed in the top 10% of their subject areas.
“This growth highlights our commitment to supporting open, trusted science”
What is CiteScore and how is it measured?
CiteScore metrics are developed by Elsevier as an alternative to the Impact Factor. They measure the citation impact of journals and can be accessed freely on Scopus. The metric represents the yearly average number of citations to recent articles published in a journal. If you’re interested in learning more about citation metrics and how we use them, check out this blog post.
Why is this important?
These results show the growing recognition for, and impact of, MDPI journals across disciplines. CiteScore rankings help researchers, institutions, and funders assess where high-quality work is being published. This growth improves our journals’ positioning in the publishing landscape and highlights our commitment to supporting open, trusted science.
Inside MDPI
Highlights from the MDPI USA Summit in Boston (5–6 June)
With several Summits already behind us, I think this is a good time to reflect on the purpose of these Summits.
Why do we organize MDPI Summits?
These one-and-a-half-day, invite-only gatherings are designed to improve our relationships with Chief Editors who lead our journals and are respected voices in their fields. The Summits aim to:
- Share MDPI’s values, achievements, editorial practices, and local market collaborations.
- Collect feedback on MDPI operations and journal practices.
- Empower Chief Editors to confidently represent MDPI beyond the Summit.
While Chief Editors know their journals well, these events help them better understand MDPI. We want them to be ambassadors for our brand. The aim is for them to walk away informed, engaged, and equipped to share positively about MDPI.
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About the Boston Summit
Held on 5–6 June, our first USA Summit gathered over 25 Chief Editors to learn more about MDPI’s activities and collaborations in the USA. The program included presentations, Q&A, and a panel discussion.
Agenda Highlights:
Moderated by Summer Huggard (Operations Manager [Toronto], MDPI), the program featured:
- MDPI Overview and USA Collaboration – Stefan Tochev (CEO, MDPI)
- AI in Publishing and MDPI's Actions – Feichi Lu (Junior Data Scientist, MDPI)
- MDPI Editorial Process and Research Integrity – Dr. Giulia Stefenelli (Scientific Communications Lead, MDPI)
- Panel Discussion – Stefan, Feichi, Giulia, Claudia
- Society Partnerships – Dr. Clàudia Aunós (Society Partnerships Senior Manager, MDPI)
- Voice of the Customer and Closing Remarks – Stefan Tochev (CEO, MDPI)
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MDPI & the USA: Facts and Figures
- With over 216,000 publications, the USA is MDPI’s second-largest contributor after China.
- In 2024, the USA ranked 2nd in total submissions and 2nd in total MDPI publications, with more than 28,200 publications.
- As of 2020, the cumulative number of authors from the USA until April 2025 was 352,099.
- As at April 2025, there are more than 12,035 active Editorial Board Members (EBMs) from the USA, with 55% having an H-index over 26.
- Among them, 96 serve as Editors-in-Chief (EiC) and 218 as section-Editors-in-Chief (SEiC)
- MDPI has more than 920 Institutional Open Access Program agreements worldwide, with over 130 from the USA.
A special thanks to our Toronto team, and everyone who worked behind the scenes to make this event run smoothly.
Coming Together for Science
Highlights from the MDPI France Summit in Paris (12–13 June)
We completed our first MDPI France Summit in Paris last week, and it was a special event. Attendees were engaged from beginning to end, remaining after hours to network and collaborate.
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Why a France Summit?
We chose to host a France Summit in view of the recent challenges MDPI has faced with the National Centre for Scientific Research (CNRS). What we took away from the event is that our authors and editors very much appreciate and enjoy working with us, but we need to address the concerns raised by CNRS, around Article Processing Charges (APCs) and the funding of gold open access publications.
“Our authors and editors very much enjoy working with us”
Some of the claims made in the June 2023 interview with Alain Schuhl, the Deputy CEO for Science at the CNRS, are simply not factual. For example, they state that MDPI’s “average APC charges per article are now around the same as Springer Nature’s.” Here is the relevant passage, reproduced verbatim:
This is not accurate.
A recent preprint analysing APC data from Elsevier, Springer Nature, Wiley, PLOS, MDPI, and Frontiers (2019–2023) shows that MDPI’s average APCs remain significantly lower than those of Springer Nature and several other major publishers.
The MDPI Summits are part of our outreach and communication efforts to address misconceptions and clarify MDPI’s position as one of the most accessible and affordable major gold open access publishers in the world.
Summit Overview
Held on 12–13 June, the France Summit gathered over 20 Chief Editors to learn more about MDPI’s activities and collaborations in France. Many of these editors are influential in their institutions and professional societies. Several also have connections to CNRS, which makes this an important opportunity to clarify how we operate and build trust through open and transparent communication and hopefully turn our editors into informed advocates of MDPI.
Summit Feedback
The feedback has been very positive, with most attendees completing the post-event survey and all rating the experience as Excellent or Good. A few highlights:
- “The whole thing was highly professional and, above all, provided quantified details that will allow us to better answer questions surrounding MDPI.”
- “The summit was an opportunity to meet personally various people directly engaged in the organization and policies of MDPI, which made it possible to clarify some important points concerning publishing with MDPI.”
- “Very well organized! A great opportunity to see all French MDPI partners and editors.”
Program Highlights:
Moderated by Miruna Adelina Nicolcioiu (Senior Conference Producer), the program featured:
- MDPI Overview and France Collaboration – Stefan Tochev (CEO)
- MDPI Editorial Process and Peer-Review Quality – Dr. Marta Colomer (Public Affairs Specialist)
- Institutional Partnerships and Open Access Funding Models – Becky Castellon (Institutional Partnerships Manager)
- AI in Publishing and MDPI's Actions – Daniele Raimondi (Data Scientist)
- Publication Ethics: Global Trends – Diana Cristina Apodaritei (Research Integrity Specialist)
- Closing Remarks – Stefan Tochev
- Panel Discussion – Diana, Becky, Prof. Dr. Patrick Da Cost, and Stefan
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MDPI & France: Facts and Figures
- With over 51,000 publications, France is MDPI's tenth-largest contributor, and fifth largest among EU countries after Italy, Spain, Germany, and Poland.
- As of 2020, the cumulative number of authors from France until April 2025 was 87,592.
- As at April 2025, there are more than 2,800 active Editorial Board Members (EBMs) from France, with 59% having an H-index over 26.
- Among them, 22 serve as Editors-in-Chief (EiC) and 61 as section-Editors-in-Chief (SEiC)
- In 2024, IJMS, JCM, and Molecules were the top three MDPI journals in terms of submissions from French-affiliated authors.
Special thanks to our colleagues from Romanian offices for organizing this successful event.
Closing Thoughts
Richard DiMarchi and Rolf Müller Share the 2024 Tu Youyou Award
As we wrap up this month’s newsletter, I’d like to take a moment to recognize the winners of the 2024 Tu Youyou Award, presented by our journal Molecules. I am pleased to share that the 2024 Tu Youyou Award has been conferred upon Richard DiMarchi and Rolf Müller, in recognition of their significant contributions to natural products chemistry and medicinal chemistry.
I invite you to read the editorial co-authored by the Tu Youyou Award Committee, which highlights the significance of the award and the remarkable impact of the recipients’ research.
A sincere thank-you to the 2024 Award Committee for their dedication and selection process, and congratulations once again to this year’s honourees. Your work exemplifies the kind of research MDPI is proud to support and amplify.
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About the Tu Youyou Award For further information about the award and the winners, please visit the Tu Youyou Award website. |
Chief Executive Officer
MDPI AG
24 June 2025
Metabolites | Highly Cited Papers Published in 2023–2024 and Hot Topic Special Issues in the “Plant Metabolism” Section
We are delighted to share some of the highly cited papers from the Section “Plant Metabolism” that were published in Metabolites (ISSN: 2218-1989) in 2023 and 2024. In addition, some Special Issues related to this topic are currently open for submission.
The following is a list of articles and Special Issues that we believe will be interest of you:
1. “Centella asiatica and Its Metabolite Asiatic Acid: Wound Healing Effects and Therapeutic Potential”
by Lúcio Ricardo Leite Diniz, Leonardo Luiz Calado, Allana Brunna Sucupira Duarte and Damião Pergentino de Sousa
Metabolites 2023, 13(2), 276; https://doi.org/10.3390/metabo13020276
Available online: https://www.mdpi.com/2218-1989/13/2/276
2. “The Role of Quorum Sensing Molecules in Bacterial–Plant Interactions”
by Jan Majdura, Urszula Jankiewicz, Agnieszka Gałązka and Sławomir Orzechowski
Metabolites 2023, 13(1), 114; https://doi.org/10.3390/metabo13010114
Available online: https://www.mdpi.com/2218-1989/13/1/114
3. “Biosynthetic Pathways of Hormones in Plants”
by Andrzej Bajguz and Alicja Piotrowska-Niczyporuk
Metabolites 2023, 13(8), 884; https://doi.org/10.3390/metabo13080884
Available online: https://www.mdpi.com/2218-1989/13/8/884
4. “Phytochemicals and Regulation of NF-kB in Inflammatory Bowel Diseases: An Overview of In Vitro and In Vivo Effects”
by Lucas Fornari Laurindo, Ana Rita de Oliveira dos Santos, Antonelly Cassio Alves de Carvalho, Marcelo Dib Bechara, Elen Landgraf Guiguer, Ricardo de Alvares Goulart, Renata Vargas Sinatora, Adriano Cressoni Araújo and Sandra Maria Barbalho
Metabolites 2023, 13(1), 96; https://doi.org/10.3390/metabo13010096
Available online: https://www.mdpi.com/2218-1989/13/1/96
5. “Optimization of Phenolic Compounds Extraction and Antioxidant Activity from Inonotus hispidus Using Ultrasound-Assisted Extraction Technology”
by Liliana Machado-Carvalho, Tânia Martins, Alfredo Aires and Guilhermina Marques
Metabolites 2023, 13(4), 524; https://doi.org/10.3390/metabo13040524
Available online: https://www.mdpi.com/2218-1989/13/4/524
6. “Metabolomics Reveals Antioxidant Metabolites in Colored Rice Grains”
by Jinyan Zhu, Ruizhi Wang, Yu Zhang, Yanyao Lu, Shuo Cai and Qiangqiang Xiong
Metabolites 2024, 14(2), 120; https://doi.org/10.3390/metabo14020120
Available online: https://www.mdpi.com/2218-1989/14/2/120
7. “Widely Targeted Metabolomic Analysis Provides New Insights into the Effect of Rootstocks on Citrus Fruit Quality”
by Min Wang, Yang Chen, Shuang Li, Jianjun Yu, Lei Yang and Lin Hong
Metabolites 2024, 14(4), 242; https://doi.org/10.3390/metabo14040242
Available online: https://www.mdpi.com/2218-1989/14/4/242
8. “Phylogenetic and Expression Analysis of the Sucrose Synthase and Sucrose Phosphate Synthase Gene Family in Potatoes”
by Jun Hu, Yanfeng Duan, Jinxue Hu, Shuqing Zhang and Guangcun Li
Metabolites 2024, 14(1), 70; https://doi.org/10.3390/metabo14010070
Available online: https://www.mdpi.com/2218-1989/14/1/70
9. “5-ALA, DTA-6, and Nitrogen Mitigate NaCl Stress by Promoting Photosynthesis and Carbon Metabolism in Rice Seedlings”
by Yaxin Wang, Chaolu Tan, Yinghao Li, Fengyan Meng, Youwei Du, Shuyu Zhang, Wenxin Jiang, Naijie Feng, Liming Zhao and Dianfeng Zheng
Metabolites 2024, 14(3), 142; https://doi.org/10.3390/metabo14030142
Available online: https://www.mdpi.com/2218-1989/14/3/142
10. “Effect of Arbuscular Mycorrhizal Fungi and Rock Phosphate on Growth, Physiology, and Biochemistry of Carob under Water Stress and after Rehydration in Vermicompost-Amended Soil”
by Abderrahim Boutasknit, Mohamed Ait-El-Mokhtar, Boujemaa Fassih, Raja Ben-Laouane, Said Wahbi and Abdelilah Meddich
Metabolites 2024, 14(4), 202; https://doi.org/10.3390/metabo14040202
Available online: https://www.mdpi.com/2218-1989/14/4/202
Special Issues:
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“Roles of Plant Secondary Metabolites in Preventing and Treating Chemotherapy-Induced Side Effects” |
“Phytochemicals and Pharmacological Significance of Plant Secondary Metabolites in Medicine” |
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“Analysis of Specialized Metabolites in Natural Products” |
“Unlocking Nature's Toolbox: Advances in Plant Metabolites Identification” |
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“Identification of Plant Metabolites: Characterization and Biological Activities, 2nd Edition” |
“Plant Biotic and Abiotic Stress Responses and Tolerance: Phytohormonal and Metabolic Insights” |
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24 June 2025
Metabolites | Highly Cited Papers Published in 2023–2024 and Hot Topic Special Issues in the “Nutrition and Metabolism” Section
We are delighted to share some of the highly cited papers from the Section “Nutrition and Metabolism” that were published in Metabolites (ISSN: 2218-1989) in 2023 and 2024. In addition, some Special Issues related to this topic are currently open for submission.
The following is a list of articles and Special Issues that we believe will be interest of you:
1. “Obesity-Induced Brain Neuroinflammatory and Mitochondrial Changes”
by Luisa O. Schmitt and Joana M. Gaspar
Metabolites 2023, 13(1), 86; https://doi.org/10.3390/metabo13010086
Available online: https://www.mdpi.com/2218-1989/13/1/86
2. “Antioxidants as Protection against Reactive Oxidative Stress in Inflammatory Bowel Disease”
by Sara Jarmakiewicz-Czaja, Katarzyna Ferenc and Rafał Filip
Metabolites 2023, 13(4), 573; https://doi.org/10.3390/metabo13040573
Available online: https://www.mdpi.com/2218-1989/13/4/573
3. “A Machine-Learning Approach to Target Clinical and Biological Features Associated with Sarcopenia: Findings from Northern and Southern Italian Aging Populations”
by Roberta Zupo, Alessia Moroni, Fabio Castellana, Clara Gasparri, Feliciana Catino, Luisa Lampignano, Simone Perna, Maria Lisa Clodoveo, Rodolfo Sardone and Mariangela Rondanelli
Metabolites 2023, 13(4), 565; https://doi.org/10.3390/metabo13040565
Available online: https://www.mdpi.com/2218-1989/13/4/565
4. “Maternal Mineral Nutrition Regulates Fetal Genomic Programming in Cattle: A Review”
by Muhammad Anas, Wellison J. S. Diniz, Ana Clara B. Menezes, Lawrence P. Reynolds, Joel S. Caton, Carl R. Dahlen and Alison K. Ward
Metabolites 2023, 13(5), 593; https://doi.org/10.3390/metabo13050593
Available online: https://www.mdpi.com/2218-1989/13/5/593
5. “Obesity, Dietary Fats, and Gastrointestinal Cancer Risk-Potential Mechanisms Relating to Lipid Metabolism and Inflammation”
by Kathleen A. J. Mitchelson, Fiona O’Connell, Jacintha O’Sullivan and Helen M. Roche
Metabolites 2024, 14(1), 42; https://doi.org/10.3390/metabo14010042
Available online: https://www.mdpi.com/2218-1989/14/1/42
6. “Iron Absorption: Molecular and Pathophysiological Aspects”
by Margherita Correnti, Elena Gammella, Gaetano Cairo and Stefania Recalcati
Metabolites 2024, 14(4), 228; https://doi.org/10.3390/metabo14040228
Available online: https://www.mdpi.com/2218-1989/14/4/228
7. “Physiological Perturbations in Combat Sports: Weight Cycling and Metabolic Function—A Narrative Review”
by Modesto A. Lebron, Jeffrey R. Stout and David H. Fukuda
Metabolites 2024, 14(2), 83; https://doi.org/10.3390/metabo14020083
Available online: https://www.mdpi.com/2218-1989/14/2/83
8. “Serum Uric Acid/Serum Creatinine Ratio and Cardiovascular Mortality in Diabetic Individuals—The Uric Acid Right for Heart Health (URRAH) Project”
by Lanfranco D’Elia, Maria Masulli, Pietro Cirillo, Agostino Virdis, Edoardo Casiglia, Valerie Tikhonoff, Fabio Angeli, Carlo Maria Barbagallo, Michele Bombelli, Federica Cappelli et al.
Metabolites 2024, 14(3), 164; https://doi.org/10.3390/metabo14030164
Available online: https://www.mdpi.com/2218-1989/14/3/164
9. “The Effect of L-Carnitine on Critical Illnesses Such as Traumatic Brain Injury (TBI), Acute Kidney Injury (AKI), and Hyperammonemia (HA)”
by Bharti Sharma, Lee Schmidt, Cecilia Nguyen, Samantha Kiernan, Jacob Dexter-Meldrum, Zachary Kuschner, Scott Ellis, Navin D. Bhatia, George Agriantonis, Jennifer Whittington et al.
Metabolites 2024, 14(7), 363; https://doi.org/10.3390/metabo14070363
Available online: https://www.mdpi.com/2218-1989/14/7/363
10. “Relationships and Mendelian Randomization of Gut Microbe-Derived Metabolites with Metabolic Syndrome Traits in the METSIM Cohort”
by Sahereh Mirzaei, Holli A. DeVon, Rita M. Cantor, Arjen J. Cupido, Calvin Pan, Sung Min Ha, Lilian Fernandes Silva, James R. Hilser, Jaana Hartiala, Hooman Allayee et al.
Metabolites 2024, 14(3), 174; https://doi.org/10.3390/metabo14030174
Available online: https://www.mdpi.com/2218-1989/14/3/174
11. “Grape/Blueberry Anthocyanins and Their Gut-Derived Metabolites Attenuate LPS/Nigericin-Induced Inflammasome Activation by Inhibiting ASC Speck Formation in THP-1 Monocytes”
by Inken Behrendt, Isabella Röder, Frank Will, Gabriela Michel, Elvira Friedrich, Daniela Grote, Zoe Martin, Hanna Pauline Dötzer, Mathias Fasshauer, Martin Speckmann et al.
Metabolites 2024, 14(4), 203; https://doi.org/10.3390/metabo14040203
Available online: https://www.mdpi.com/2218-1989/14/4/203
12. “Effects of the Menstrual Cycle and Hormonal Contraceptive Use on Metabolic Outcomes, Strength Performance, and Recovery: A Narrative Review”
by Hannah E. Cabre, Lacey M. Gould, Leanne M. Redman and Abbie E. Smith-Ryan
Metabolites 2024, 14(7), 347; https://doi.org/10.3390/metabo14070347
Available online: https://www.mdpi.com/2218-1989/14/7/347
13. “Fetal Hepatic Lipidome Is More Greatly Affected by Maternal Rate of Gain Compared with Vitamin and Mineral Supplementation at day 83 of Gestation”
by Ana Clara B. Menezes, Carl R. Dahlen, Kacie L. McCarthy, Cierrah J. Kassetas, Friederike Baumgaertner, James D. Kirsch, Sheri T. Dorsam, Tammi L. Neville, Alison K. Ward, Pawel P. Borowicz et al.
Metabolites 2023, 13(2), 175; https://doi.org/10.3390/metabo13020175
Available online: https://www.mdpi.com/2218-1989/13/2/175
14. “Effectiveness of Intermittent Hypoxia–Hyperoxia Therapy in Different Pathologies with Possible Metabolic Implications”
by Andreea-Bianca Uzun, Mădălina Gabriela Iliescu, Liliana-Elena Stanciu, Elena-Valentina Ionescu, Rodica Ana Ungur, Viorela Mihaela Ciortea, Laszlo Irsay, Irina Motoașcă, Marius Nicolae Popescu, Florina Ligia Popa et al.
Metabolites 2023, 13(2), 181; https://doi.org/10.3390/metabo13020181
Available online: https://www.mdpi.com/2218-1989/13/2/181
15. “The Link between Trace Metal Elements and Glucose Metabolism: Evidence from Zinc, Copper, Iron, and Manganese-Mediated Metabolic Regulation”
by Zhendong Sun, Yuzhuo Shao, Kunhao Yan, Tianzhao Yao, Lulu Liu, Feifei Sun, Jiarui Wu and Yunpeng Huang
Metabolites 2023, 13(10), 1048; https://doi.org/10.3390/metabo13101048
Available online: https://www.mdpi.com/2218-1989/13/10/1048
Special Issues:
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“Nutritional Intervention and Metabolic Health: Multi-Omics Insights” |
“Advances in Murine Models for Metabolic Diseases: Insights into Diabetes, Obesity, and Cardiovascular Conditions” |
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“Bioactive Food Ingredients in Prevention and Alleviation of Metabolic Diseases” |
“Metabolomics Techniques in Nutrition and Pharmacy Research” |
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“Nutrition, Metabolism and Physiology in Aquatic Animals” |
“Plant-Derived Molecules in Prevention of Metabolic and Oxidative Stress-Related Diseases” |
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“Neuronutrition: Metabolomic Insights and Perspectives” |
“Brain Metabolic Alterations in Neurodegenerative Diseases” |
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24 June 2025
Metabolites | Highly Cited Papers Published in 2023–2024 and Hot Topic Special Issues in the “Bioinformatics and Data Analysis” Section
We are delighted to share some of the highly cited papers from the Section “Bioinformatics and Data Analysis” that were published in Metabolites (ISSN: 2218-1989) in 2023 and 2024. In addition, some Special Issues related to this topic are currently open for submission.
The following is a list of articles and Special Issues that we believe will be interest of you:
1. “Integrating Omics Data in Genome-Scale Metabolic Modeling: A Methodological Perspective for Precision Medicine”
by Partho Sen and Matej Orešič
Metabolites 2023, 13(7), 855; https://doi.org/10.3390/metabo13070855
Available online: https://www.mdpi.com/2218-1989/13/7/855
2. “Obstructive Sleep Apnea, Metabolic Dysfunction, and Periodontitis—Machine Learning and Statistical Analyses of the Dental, Oral, Medical Epidemiological (DOME) Big Data Study”
by Noya Ytzhaik, Dorit Zur, Chen Goldstein and Galit Almoznino
Metabolites 2023, 13(5), 595; https://doi.org/10.3390/metabo13050595
Available online: https://www.mdpi.com/2218-1989/13/5/595
3. “Context-Specific Genome-Scale Metabolic Modelling and Its Application to the Analysis of COVID-19 Metabolic Signatures”
by Miha Moškon and Tadeja Režen
Metabolites 2023, 13(1), 126; https://doi.org/10.3390/metabo13010126
Available online: https://www.mdpi.com/2218-1989/13/1/126
4. “The Omics Dashboard for Interactive Exploration of Metabolomics and Multi-Omics Data”
by Suzanne Paley and Peter D. Karp
Metabolites 2024, 14(1), 65; https://doi.org/10.3390/metabo14010065
Available online: https://www.mdpi.com/2218-1989/14/1/65
5. “Explainable AI to Facilitate Understanding of Neural Network-Based Metabolite Profiling Using NMR Spectroscopy”
by Hayden Johnson and Aaryani Tipirneni-Sajja
Metabolites 2024, 14(6), 332; https://doi.org/10.3390/metabo14060332
Available online: https://www.mdpi.com/2218-1989/14/6/332
6. “MAD HATTER Correctly Annotates 98% of Small Molecule Tandem Mass Spectra Searching in PubChem”
by Martin A. Hoffmann, Fleming Kretschmer, Marcus Ludwig and Sebastian Böcker
Metabolites 2023, 13(3), 314; https://doi.org/10.3390/metabo13030314
Available online: https://www.mdpi.com/2218-1989/13/3/314
7. “Comparison of Compound Identification Tools Using Data Dependent and Data Independent High-Resolution Mass Spectrometry Spectra”
by Rosalie Nijssen, Marco H. Blokland, Robin S. Wegh, Erik de Lange, Stefan P. J. van Leeuwen,
Bjorn J. A. Berendsen and Milou G. M. van de Schans
Metabolites 2023, 13(7), 777; https://doi.org/10.3390/metabo13070777
Available online: https://www.mdpi.com/2218-1989/13/7/777
8. “Optimization Strategies for Mass Spectrometry-Based Untargeted Metabolomics Analysis of Small Polar Molecules in Human Plasma”
by Michał Kaczmarek, Nanyun Zhang, Ludmila Buzhansky, Sharon Gilead and Ehud Gazit
Metabolites 2023, 13(8), 923; https://doi.org/10.3390/metabo13080923
Available online: https://www.mdpi.com/2218-1989/13/8/923
9. “md_harmonize: A Python Package for Atom-Level Harmonization of Public Metabolic Databases”
by Huan Jin and Hunter N. B. Moseley
Metabolites 2023, 13(12), 1199; https://doi.org/10.3390/metabo13121199
Available online: https://www.mdpi.com/2218-1989/13/12/1199
10. “metabCombiner 2.0: Disparate Multi-Dataset Feature Alignment for LC-MS Metabolomics”
by Hani Habra, Jennifer L. Meijer, Tong Shen, Oliver Fiehn, David A. Gaul, Facundo M. Fernández, Kaitlin R. Rempfert, Thomas O. Metz, Karen E. Peterson, Charles R. Evans et al.
Metabolites 2024, 14(2), 125; https://doi.org/10.3390/metabo14020125
Available online: https://www.mdpi.com/2218-1989/14/2/125
11. “Implementation of FAIR Practices in Computational Metabolomics Workflows—A Case Study”
by Mahnoor Zulfiqar, Michael R. Crusoe, Birgitta König-Ries, Christoph Steinbeck, Kristian Peters and Luiz Gadelha
Metabolites 2024, 14(2), 118; https://doi.org/10.3390/metabo14020118
Available online: https://www.mdpi.com/2218-1989/14/2/118
12. “Predicting the Pathway Involvement of Metabolites Based on Combined Metabolite and Pathway Features”
by Erik D. Huckvale and Hunter N. B. Moseley
Metabolites 2024, 14(5), 266; https://doi.org/10.3390/metabo14050266
Available online: https://www.mdpi.com/2218-1989/14/5/266
Special Issues:
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“Biostatistics and Bioinformatics in Metabolomics Research: From Study Design and Analytics to Clinical Insights and Public Health Implications” |
“Machine Learning Applications in Metabolomics Analysis: 2nd Edition” |
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“Machine Learning in Metabolomics: Unlocking the Future of Data Analysis” |
“Metabolomics and Computational Research on Drugs and Diseases” |
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24 June 2025
Metabolites | Highly Cited Papers Published in 2023–2024 and Hot Topic Special Issues in the “Metabolomic Profiling Technology” Section
We are delighted to share some of the highly cited papers from the Section “Metabolomic Profiling Technology” that were published in Metabolites (ISSN: 2218-1989) in 2023 and 2024. In addition, some Special Issues related to this topic are currently open for submission.
The following is a list of articles and Special Issues that we believe will be interest of you:
1. “Therapeutic and Toxic Effects of Valproic Acid Metabolites”
by Natalia A. Shnayder, Violetta V. Grechkina, Aiperi K. Khasanova, Elena N. Bochanova, Evgenia A. Dontceva, Marina M. Petrova, Azat R. Asadullin, German A. Shipulin, Kuanysh S. Altynbekov, Mustafa Al-Zamil et al.
Metabolites 2023, 13(1), 134; https://doi.org/10.3390/metabo13010134
Available online: https://www.mdpi.com/2218-1989/13/1/134
2. “Instrumental Drift in Untargeted Metabolomics: Optimizing Data Quality with Intrastudy QC Samples”
by Andre Märtens, Johannes Holle, Brit Mollenhauer, Andre Wegner, Jennifer Kirwan and Karsten Hiller
Metabolites 2023, 13(5), 665; https://doi.org/10.3390/metabo13050665
Available online: https://www.mdpi.com/2218-1989/13/5/665
3. “Revolutionizing Blood Collection: Innovations, Applications, and the Potential of Microsampling Technologies for Monitoring Metabolites and Lipids”
by Eleonora Bossi, Elena Limo, Lisa Pagani, Nicole Monza, Simone Serrao, Vanna Denti, Giuseppe Astarita and Giuseppe Paglia
Metabolites 2024, 14(1), 46; https://doi.org/10.3390/metabo14010046
Available online: https://www.mdpi.com/2218-1989/14/1/46
4. “Challenges in the Metabolomics-Based Biomarker Validation Pipeline”
by Shenghan Li, Nikita Looby, Vinod Chandran and Vathany Kulasingam
Metabolites 2024, 14(4), 200; https://doi.org/10.3390/metabo14040200
Available online: https://www.mdpi.com/2218-1989/14/4/200
5. “Optimized Mass Spectrometry Detection of Thyroid Hormones and Polar Metabolites in Rodent Cerebrospinal Fluid”
by Ryann M. Fame, Ilhan Ali, Maria K. Lehtinen, Naama Kanarek and Boryana Petrova
Metabolites 2024, 14(2), 79; https://doi.org/10.3390/metabo14020079
Available online: https://www.mdpi.com/2218-1989/14/2/79
6. “Accurate Prediction of 1H NMR Chemical Shifts of Small Molecules Using Machine Learning”
by Tanvir Sajed, Zinat Sayeeda, Brian L. Lee, Mark Berjanskii, Fei Wang, Vasuk Gautam and David S. Wishart
Metabolites 2024, 14(5), 290; https://doi.org/10.3390/metabo14050290
Available online: https://www.mdpi.com/2218-1989/14/5/290
7. “An Overview of Pre-Analytical Factors Impacting Metabolomics Analyses of Blood Samples”
by Amy Thachil, Li Wang, Rupasri Mandal, David Wishart and Tom Blydt-Hansen
Metabolites 2024, 14(9), 474; https://doi.org/10.3390/metabo14090474
Available online: https://www.mdpi.com/2218-1989/14/9/474
8. “Volumetric Absorptive Microsampling in the Analysis of Endogenous Metabolites”
by Daniel Marques de Sá e Silva, Marlene Thaitumu, Georgios Theodoridis, Michael Witting and Helen Gika
Metabolites 2023, 13(10), 1038; https://doi.org/10.3390/metabo13101038
Available online: https://www.mdpi.com/2218-1989/13/10/1038
9. “Metabolic Bile Acid Profile Impairments in Dogs Affected by Chronic Inflammatory Enteropathy”
by Rossana Comito, Emanuele Porru, Nicolò Interino, Matteo Conti, Rossella Terragni, Roberto Gotti, Marco Candela, Patrizia Simoni, Aldo Roda and Jessica Fiori
Metabolites 2023, 13(9), 980; https://doi.org/10.3390/metabo13090980
Available online: https://www.mdpi.com/2218-1989/13/9/980
10. “Evaluation of Lipid Extraction Protocols for Untargeted Analysis of Mouse Tissue Lipidome”
by Ashraf M. Omar and Qibin Zhang
Metabolites 2023, 13(9), 1002; https://doi.org/10.3390/metabo13091002
Available online: https://www.mdpi.com/2218-1989/13/9/1002
11. “Opening the Random Forest Black Box of 1H NMR Metabolomics Data by the Exploitation of Surrogate Variables”
by Soeren Wenck, Thorsten Mix, Markus Fischer, Thomas Hackl and Stephan Seifert
Metabolites 2023, 13(10), 1075; https://doi.org/10.3390/metabo13101075
Available online: https://www.mdpi.com/2218-1989/13/10/1075
12. “Comparison of Various Extraction Approaches for Optimized Preparation of Intracellular Metabolites from Human Mesenchymal Stem Cells and Fibroblasts for NMR-Based Study”
by Slavomíra Nováková, Eva Baranovičová, Zuzana Hatoková, Gábor Beke, Janka Pálešová, Romana Záhumenská, Bibiána Baďurová, Mária Janíčková, Ján Strnádel, Erika Halašová et al.
Metabolites 2024, 14(5), 268; https://doi.org/10.3390/metabo14050268
Available online: https://www.mdpi.com/2218-1989/14/5/268
13. “NMR Precision Metabolomics: Dynamic Peak Sum Thresholding and Navigators for Highly Standardized and Reproducible Metabolite Profiling of Clinical Urine Samples”
by Alessia Trimigno, Nicole R. Holderman, Chen Dong, Kari D. Boardman, Jifang Zhao and Elizabeth M. O’Day
Metabolites 2024, 14(5), 275; https://doi.org/10.3390/metabo14050275
Available online: https://www.mdpi.com/2218-1989/14/5/275
14. “Efficient SABRE-SHEATH Hyperpolarization of Potent Branched-Chain-Amino-Acid Metabolic Probe [1-13C]ketoisocaproate”
by Isaiah Adelabu, Md Raduanul H. Chowdhury, Shiraz Nantogma, Clementinah Oladun, Firoz Ahmed, Lukas Stilgenbauer, Marianna Sadagurski, Thomas Theis, Boyd M. Goodson and Eduard Y. Chekmenev
Metabolites 2023, 13(2), 200; https://doi.org/10.3390/metabo13020200
Available online: https://www.mdpi.com/2218-1989/13/2/200
15. “Analysis of Volatile Organic Compounds in Exhaled Breath Following a COMEX-30 Treatment Table”
by Feiko J. M. de Jong, Thijs T. Wingelaar, Paul Brinkman, Pieter-Jan A. M. van Ooij, Anke H. Maitland-van der Zee, Markus W. Hollmann and Rob A. van Hulst
Metabolites 2023, 13(3), 316; https://doi.org/10.3390/metabo13030316
Available online: https://www.mdpi.com/2218-1989/13/3/316
Special Issues:
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“Integration of Emerging Technologies in Metabolite Analysis” |
“NMR-Based Metabolomics in Biomedicine and Food Science” |
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“New Technology and Workflows for Advancing Metabolomics” |
“Application of NMR in Food Metabolomics” |
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“Mass Spectrometry-Based Technology for Metabolic Profiling” |
“Mass Spectrometry Imaging and Spatial Metabolomics” |
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“Advances in LC-MS-Based Metabolomics: From (Un)targeted Screening to Structural Elucidation” |
“The Role of Isotope Tracers in Investigating Metabolic Disorders” |
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24 June 2025
Metabolites | Highly Cited Papers Published in 2023–2024 and Hot Topic Special Issues in the “Food Metabolomics” Section
We are delighted to share some of the highly cited papers from the Section “Food Metabolomics” that were published in Metabolites (ISSN: 2218-1989) in 2023 and 2024. In addition, some Special Issues related to this topic are currently open for submission.
The following is a list of articles and Special Issues that we believe will be interest of you:
1. “Unexpected Value of Honey Color for Prediction of a Non-Enzymatic H2O2 Production and Honey Antibacterial Activity: A Perspective”
by Katrina Brudzynski
Metabolites 2023, 13(4), 526; https://doi.org/10.3390/metabo13040526
Available online: https://www.mdpi.com/2218-1989/13/4/526
2. “Mycotoxin Contamination Status of Cereals in China and Potential Microbial Decontamination Methods”
by Jing Zhang, Xi Tang, Yifan Cai and Wen-Wen Zhou
Metabolites 2023, 13(4), 551; https://doi.org/10.3390/metabo13040551
Available online: https://www.mdpi.com/2218-1989/13/4/551
3. “Qualitative Analysis of Polyphenols in Glycerol Plant Extracts Using Untargeted Metabolomics”
by Joseph Robert Nastasi 1, Venea Dara Daygon, Vassilis Kontogiorgos and Melissa A. Fitzgerald
Metabolites 2023, 13(4), 566; https://doi.org/10.3390/metabo13040566
Available online: https://www.mdpi.com/2218-1989/13/4/566
4. “Efficacy Confirmation Test of Black Cumin (Nigella sativa L.) Seeds Extract Using a High-Fat Diet Mouse Model”
by Khawaja Muhammad Imran Bashir, Joo Wan Kim, Jong-Kyu Kim, Yoon-Seok Chun, Jae-Suk Choi and Sae-Kwang Ku
Metabolites 2023, 13(4), 501; https://doi.org/10.3390/metabo13040501
Available online: https://www.mdpi.com/2218-1989/13/4/501
5. “Donkey Colostrum and Milk: How Dietary Probiotics Can Affect Metabolomic Profile, Alkaline Sphingomyelinase and Alkaline Phosphatase Activity”
by Fulvio Laus, Luca Laghi, Marilena Bazzano, Maria Grazia Cifone, Benedetta Cinque, Yaosen Yang and Andrea Marchegiani
Metabolites 2023, 13(5), 622; https://doi.org/10.3390/metabo13050622
Available online: https://www.mdpi.com/2218-1989/13/5/622
6. “Hypolipidemic Effects of Beetroot Juice in SHR-CRP and HHTg Rat Models of Metabolic Syndrome: Analysis of Hepatic Proteome”
by Jan Šilhavý, Petr Mlejnek, Miroslava Šimáková, Hana Malínská, Irena Marková, Martina Hüttl, Denisa Miklánková, Ludmila Kazdová, Marek Vrbacký, Alena Pecinová et al.
Metabolites 2023, 13(2), 192; https://doi.org/10.3390/metabo13020192
Available online: https://www.mdpi.com/2218-1989/13/2/192
7. “Comprehensive Strategies for Metabolic Syndrome: How Nutrition, Dietary Polyphenols, Physical Activity, and Lifestyle Modifications Address Diabesity, Cardiovascular Diseases, and Neurodegenerative Conditions”
by Giovanni Martemucci, Mohamad Khalil, Alessio Di Luca, Hala Abdallah and Angela Gabriella D’Alessandro
Metabolites 2024, 14(6), 327; https://doi.org/10.3390/metabo14060327
Available online: https://www.mdpi.com/2218-1989/14/6/327
8. “Potential of Chlorogenic Acid in the Management of Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD): Animal Studies and Clinical Trials—A Narrative Review”
by Agnieszka Ziółkiewicz, Przemysław Niziński, Jakub Soja, Tomasz Oniszczuk, Maciej Combrzyński, Adrianna Kondracka and Anna Oniszczuk
Metabolites 2024, 14(6), 346; https://doi.org/10.3390/metabo14060346
Available online: https://www.mdpi.com/2218-1989/14/6/346
9. “New Implications of Metabolites and Free Fatty Acids in Quality Control of Crossbred Wagyu Beef during Wet Aging Cold Storage”
by Shuji Ueda, Yuka Yoshida, Biniam Kebede, Chiaki Kitamura, Ryo Sasaki, Masakazu Shinohara, Itsuko Fukuda and Yasuhito Shirai
Metabolites 2024, 14(2), 95; https://doi.org/10.3390/metabo14020095
Available online: https://www.mdpi.com/2218-1989/14/2/95
10. “Metabolomics Reveals the Effects of Nitrogen/Phosphorus/Potassium (NPK) Fertilizer Levels on Cucumber Fruit Raised in Different Nutrient Soils”
by Na-Rae Lee, Yangmin X. Kim, Yerim Lee, Chanwook Lee, Yosung Song, Hyejin Park, Choong Hwan Lee and Yejin Lee
Metabolites 2024, 14(2), 102; https://doi.org/10.3390/metabo14020102
Available online: https://www.mdpi.com/2218-1989/14/2/102
11. “Time-Course Metabolomic Analysis: Production of Betaine Structural Analogs by Fungal Fermentation of Seaweed”
by Nao Inoue, Keisuke Tsuge, Teruyoshi Yanagita, Akira Oikawa and Koji Nagao
Metabolites 2024, 14(4), 201; https://doi.org/10.3390/metabo14040201
Available online: https://www.mdpi.com/2218-1989/14/4/201
Special Issues:
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“Emerging Applications of Metabolomics in Fermented Food” |
“New Insights into Microalgae Metabolism” |
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“Metabolomics in Food Science and Nutrition Using GC-MS” |
“Advances in Food Metabolomics for Functional Food Development and Analysis” |
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“Effects of Micronutrients on Human Metabolism” |
“Advances in Food Sciences: Metabolomics to Unravel the Complexity of Food Metabolites” |
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24 June 2025
Metabolites | Highly Cited Papers Published in 2023–2024 and Hot Topic Special Issues in the “Integrative Metabolomics” Section
We are delighted to share some of the highly cited papers from the Section “Integrative Metabolomics” that were published in Metabolites (ISSN: 2218-1989) in 2023 and 2024. In addition, some Special Issues related to this topic are currently open for submission.
The following is a list of articles and Special Issues that we believe will be interest of you:
1. “Activity of Microbial-Derived Phenolic Acids and Their Conjugates against LPS-Induced Damage in Neuroblastoma Cells and Macrophages”
by Dolores González de Llano, Mikel Roldán, Laura Parro, Begoña Bartolomé and M. Victoria Moreno-Arribas
Metabolites 2023, 13(1), 108; https://doi.org/10.3390/metabo13010108
Available online: https://www.mdpi.com/2218-1989/13/1/108
2. “Metabolic Contributions to Pathobiology of Asthma”
by Tamanna Roshan Lal, Laura Reck Cechinel, Robert Freishtat and Deepa Rastogi
Metabolites 2023, 13(2), 212; https://doi.org/10.3390/metabo13020212
Available online: https://www.mdpi.com/2218-1989/13/2/212
3. “Crucial Regulatory Role of Organokines in Relation to Metabolic Changes in Non-Diabetic Obesity”
by Hajnalka Lőrincz, Sándor Somodi, Balázs Ratku, Mariann Harangi and György Paragh
Metabolites 2023, 13(2), 270; https://doi.org/10.3390/metabo13020270
Available online: https://www.mdpi.com/2218-1989/13/2/270
4. “Childhood Obesity and the Cryptic Language of the Microbiota: Metabolomics’ Upgrading”
by Alice Bosco, Michele Loi, Giulia Pinna, Roberta Pintus, Vassilios Fanos and Angelica Dessì
Metabolites 2023, 13(3), 414; https://doi.org/10.3390/metabo13030414
Available online: https://www.mdpi.com/2218-1989/13/3/414
5. “Metabolomic Studies in Inborn Errors of Metabolism: Last Years and Future Perspectives”
by Marcello Cossu, Roberta Pintus, Marco Zaffanello, Michele Mussap, Fabiola Serra, Maria Antonietta Marcialis and Vassilios Fanos
Metabolites 2023, 13(3), 447; https://doi.org/10.3390/metabo13030447
Available online: https://www.mdpi.com/2218-1989/13/3/447
6. “What Has Longitudinal ‘Omics’ Studies Taught Us about Irritable Bowel Syndrome? A Systematic Review”
by Qin Xiang Ng, Chun En Yau, Clyve Yu Leon Yaow, Ryan Ian Houe Chong, Nicolette Zy-Yin Chong, Seth En Teoh, Yu Liang Lim, Alex Yu Sen Soh, Wee Khoon Ng and Julian Thumboo
Metabolites 2023, 13(4), 484; https://doi.org/10.3390/metabo13040484
Available online: https://www.mdpi.com/2218-1989/13/4/484
7. “Iodine and Thyroid Maternal and Fetal Metabolism during Pregnancy”
by Charles Mégier, Grégoire Dumery and Dominique Luton
Metabolites 2023, 13(5), 633; https://doi.org/10.3390/metabo13050633
Available online: https://www.mdpi.com/2218-1989/13/5/633
8. “Development of a Urine Metabolomics Biomarker-Based Prediction Model for Preeclampsia during Early Pregnancy”
by Yaqi Zhang, Karl G. Sylvester, Bo Jin, Ronald J. Wong, James Schilling, C. James Chou, Zhi Han, Ruben Y. Luo, Lu Tian, Subhashini Ladella et al.
Metabolites 2023, 13(6), 715; https://doi.org/10.3390/metabo13060715
Available online: https://www.mdpi.com/2218-1989/13/6/715
9. “Dietary Patterns, Gut Microbiota Remodeling, and Cardiometabolic Disease”
by Letizia Guiducci, Giuseppina Nicolini and Francesca Forini
Metabolites 2023, 13(6), 760; https://doi.org/10.3390/metabo13060760
Available online: https://www.mdpi.com/2218-1989/13/6/760
10. “Made in the Womb: Maternal Programming of Offspring Cardiovascular Function by an Obesogenic Womb”
by Mariana S. Diniz, Luís F. Grilo, Carolina Tocantins, Inês Falcão-Pires and Susana P. Pereira
Metabolites 2023, 13(7), 845; https://doi.org/10.3390/metabo13070845
Available online: https://www.mdpi.com/2218-1989/13/7/845
11. “Metabolite Biomarkers of Prolonged and Intensified Pain and Distress in Head and Neck Cancer Patients Undergoing Radio- or Chemoradiotherapy by Means of NMR-Based Metabolomics—A Preliminary Study”
by Łukasz Boguszewicz, Alicja Heyda, Mateusz Ciszek, Agata Bieleń, Agnieszka Skorupa, Jolanta Mrochem-Kwarciak, Krzysztof Składowski and Maria Sokół
Metabolites 2024, 14(1), 60; https://doi.org/10.3390/metabo14010060
Available online: https://www.mdpi.com/2218-1989/14/1/60
12. “Integrated Transcriptomics and Metabolomics Analysis Reveals the Effects of Cutting on the Synthesis of Flavonoids and Saponins in Chinese Herbal Medicine Astragalus mongholious”
by Xu Guo, Xiang Yan, Yuanyuan Wang, Zhiyong Shi, Jingping Niu, Jianping Liang and Xiaoyun Jia
Metabolites 2024, 14(2), 97; https://doi.org/10.3390/metabo14020097
Available online: https://www.mdpi.com/2218-1989/14/2/97
13. “Metabolomics and Lipidomics Analyses Aid Model Classification of Type 2 Diabetes in Non-Human Primates”
by Peining Tao, Stacey Conarello, Thomas P. Wyche, Nanyan Rena Zhang, Keefe Chng, John Kang and Theodore R. Sana
Metabolites 2024, 14(3), 159; https://doi.org/10.3390/metabo14030159
Available online: https://www.mdpi.com/2218-1989/14/3/159
14. “Pancreatic Beta Cell Function in Infants Varies by Maternal Weight”
by Lisa R. Staimez, Anubrati Dutta, Yara S. Beyh, Ruby Gupta, Hari Krishna Noule, Vyakaranam Sapna, Kothapally Deepa, Aryeh D. Stein, K.M. Venkat Narayan, Dorairaj Prabhakaran et al.
Metabolites 2024, 14(4), 208; https://doi.org/10.3390/metabo14040208
Available online: https://www.mdpi.com/2218-1989/14/4/208
Special Issues:
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“Insights into Metabolism, Diagnostics and Therapeutics of Cancer and Tumor Microenvironment by NMR Spectroscopy” |
“Advances in Metabolomics and Multi-Omics Integration” |
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“Harnessing the Power of NMR Metabolomics in Unraveling Metabolic Diseases” |
“Artificial Intelligence and Machine Learning in Metabolomics” |
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24 June 2025
Metabolites | Highly Cited Papers Published in 2023–2024 and Hot Topic Special Issues in the “Environmental Metabolomics” Section
We are delighted to share some of the highly cited papers from the Section “Environmental Metabolomics” that were published in Metabolites (ISSN: 2218-1989) in 2023 and 2024. In addition, some Special Issues related to this topic are currently open for submission.
The following is a list of articles and Special Issues that we believe will be interest of you:
1. “The Relationship between Phthalates and Diabetes: A Review”
by Melissa Mariana and Elisa Cairrao
Metabolites 2023, 13(6), 746; https://doi.org/10.3390/metabo13060746
Available online: https://www.mdpi.com/2218-1989/13/6/746
2. “Impact of Heavy Metal Exposure on Mytilus galloprovincialis Spermatozoa: A Metabolomic Investigation”
by Gennaro Lettieri, Carmela Marinaro, Rosaria Notariale, Pasquale Perrone, Martina Lombardi, Alessio Trotta, Jacopo Troisi and Marina Piscopo
Metabolites 2023, 13(8), 943; https://doi.org/10.3390/metabo13080943
Available online: https://www.mdpi.com/2218-1989/13/8/943
3. “Suitability of Short- and Long-Term Storage of Volatile Organic Compounds Samples in Syringe-Based Containers: A Comparison Study”
by Paulo Henrique Costa Santos, Pedro Catalão Moura and Valentina Vassilenko
Metabolites 2023, 13(8), 903; https://doi.org/10.3390/metabo13080903
Available online: https://www.mdpi.com/2218-1989/13/8/903
4. “Effects of Ecologically Relevant Concentrations of Cadmium on the Microbiota, Short-Chain Fatty Acids, and FFAR2 Expression in Zebrafish”
by Wenxin Jiang, Xi Wang, Yaxin Wang, Youwei Du, Shuyu Zhang, Hang Zhou, Naijie Feng, Dianfeng Zheng, Guohui Ma and Liming Zhao
Metabolites 2023, 13(5), 657; https://doi.org/10.3390/metabo13050657
Available online: https://www.mdpi.com/2218-1989/13/5/657
5. “S-ABA Enhances Rice Salt Tolerance by Regulating Na+/K+ Balance and Hormone Homeostasis”
by Wenxin Jiang, Xi Wang, Yaxin Wang, Youwei Du, Shuyu Zhang, Hang Zhou, Naijie Feng, Dianfeng Zheng, Guohui Ma and Liming Zhao
Metabolites 2024, 14(4), 181; https://doi.org/10.3390/metabo14040181
Available online: https://www.mdpi.com/2218-1989/14/4/181
6. “Cell Adhesion Molecules in Schizophrenia Patients with Metabolic Syndrome”
by Anastasiia S. Boiko, Irina A. Mednova, Elena G. Kornetova, Arkadiy V. Semke, Nikolay A. Bokhan and Svetlana A. Ivanova
Metabolites 2023, 13(3), 376; https://doi.org/10.3390/metabo13030376
Available online: https://www.mdpi.com/2218-1989/13/3/376
7. “An Exploratory Study of the Metabolite Profiling from Pesticides Exposed Workers”
by Daniela Magalhães Nolasco, Michele P. R. Mendes, Luiz Paulo de Aguiar Marciano, Luiz Filipe Costa, Adriana Nori De Macedo, Isarita Martins Sakakibara, Alessandra Cristina Pupin Silvério, Maria José N. Paiva and Leiliane C. André
Metabolites 2023, 13(5), 596; https://doi.org/10.3390/metabo13050596
Available online: https://www.mdpi.com/2218-1989/13/5/596
8. “Investigating the Acute Metabolic Effects of the N-Methyl Carbamate Insecticide, Methomyl, on Mouse Liver”
by Amy M. Groswald, Tyler C. Gripshover, Walter H. Watson, Banrida Wahlang, Jianzhu Luo, Loretta L. Jophlin and Matthew C. Cave
Metabolites 2023, 13(8), 901; https://doi.org/10.3390/metabo13080901
Available online: https://www.mdpi.com/2218-1989/13/8/901
9. “Evaluation of the Aquatic Toxicity of Several Triazole Fungicides”
by Bianca-Vanesa Boros, Diana-Larisa Roman and Adriana Isvoran
Metabolites 2024, 14(4), 197; https://doi.org/10.3390/metabo14040197
Available online: https://www.mdpi.com/2218-1989/14/4/197
10. “Volatile Organic Compounds in Cellular Headspace after Hyperbaric Oxygen Exposure: An In Vitro Pilot Study”
by Feiko J. M. de Jong, Thijs A. Lilien, Dominic W. Fenn, Thijs T. Wingelaar, Pieter-Jan A. M. van Ooij, Anke H. Maitland-van der Zee, Markus W. Hollmann, Rob A. van Hulst and Paul Brinkman
Metabolites 2024, 14(5), 281; https://doi.org/10.3390/metabo14050281
Available online: https://www.mdpi.com/2218-1989/14/5/281
Special Issues:
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“Targeted and Non-Targeted LC- and GC-HRMS Workflows for the Analysis of Emerging Contaminants and the Environmental Exposome” |
“Environmental Metabolites Insights into Health and Disease” |
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23 June 2025
Metabolites | Highly Cited Papers Published in 2023–2024 and Hot Topic Special Issues in the “Endocrinology and Clinical Metabolic Research” Section
We are delighted to share some of the highly cited papers from the Section “Endocrinology and Clinical Metabolic Research” that were published in Metabolites (ISSN: 2218-1989) in 2023 and 2024. In addition, some Special Issues related to this topic are currently open for submission.
The following is a list of articles and Special Issues that we believe will be interest of you:
1. “Metabolic Signatures Elucidate the Effect of Body Mass Index on Type 2 Diabetes”
by Qiuling Dong, Sidra Sidra, Christian Gieger, Rui Wang-Sattler, Wolfgang Rathmann, Cornelia Prehn, Jerzy Adamski, Wolfgang Koenig, Annette Peters, Harald Grallert et al.
Metabolites 2023, 13(2), 227; https://doi.org/10.3390/metabo13020227
Available online: https://www.mdpi.com/2218-1989/13/2/227
2. “The Engagement of Cytochrome P450 Enzymes in Tryptophan Metabolism”
by Anna Haduch, Ewa Bromek, Wojciech Kuban and Władysława Anna Daniel
Metabolites 2023, 13(5), 629; https://doi.org/10.3390/metabo13050629
Available online: https://www.mdpi.com/2218-1989/13/5/629
3. “Metabolic Role of Autophagy in the Pathogenesis and Development of NAFLD”
by Lingxuan An, Ulrich Wirth, Dominik Koch, Malte Schirren, Moritz Drefs, Dionysios Koliogiannis, Hanno Niess, Joachim Andrassy, Markus Guba, Alexandr V. Bazhin et al.
Metabolites 2023, 13(1), 101; https://doi.org/10.3390/metabo13010101
Available online: https://www.mdpi.com/2218-1989/13/1/101
4. “Application of Artificial Neural Networks (ANN) to Elucidate the Connections among Smell, Obesity with Related Metabolic Alterations, and Eating Habit in Patients with Weight Excess”
by Fernanda Velluzzi, Andrea Deledda, Mauro Lombardo, Michele Fosci, Roberto Crnjar, Enzo Grossi and Giorgia Sollai
Metabolites 2023, 13(2), 206; https://doi.org/10.3390/metabo13020206
Available online: https://www.mdpi.com/2218-1989/13/2/206
5. “Endpoints in NASH Clinical Trials: Are We Blind in One Eye?”
by Amedeo Lonardo, Stefano Ballestri, Alessandro Mantovani, Giovanni Targher and Fernando Bril
Metabolites 2024, 14(1), 40; https://doi.org/10.3390/metabo14010040
Available online: https://www.mdpi.com/2218-1989/14/1/40
6. “Metformin and the Liver: Unlocking the Full Therapeutic Potential”
by Federica Perazza, Laura Leoni, Santo Colosimo, Alessandra Musio, Giulia Bocedi, Michela D’Avino, Giulio Agnelli, Alba Nicastri, Chiara Rossetti, Federica Sacilotto et al.
Metabolites 2024, 14(4), 186; https://doi.org/10.3390/metabo14040186
Available online: https://www.mdpi.com/2218-1989/14/4/186
7. “Salivary Metabolites Produced by Oral Microbes in Oral Diseases and Oral Squamous Cell Carcinoma: A Review”
by Bina Kashyap and Arja Kullaa
Metabolites 2024, 14(5), 277; https://doi.org/10.3390/metabo14050277
Available online: https://www.mdpi.com/2218-1989/14/5/277
8. “Role of the Adrenal Medulla in Hypoglycaemia-Associated Autonomic Failure—A Diabetic Perspective”
by Manjula Senthilkumaran, Coen Koch, Mauritz Frederick Herselman and Larisa Bobrovskaya
Metabolites 2024, 14(2), 100; https://doi.org/10.3390/metabo14020100
Available online: https://www.mdpi.com/2218-1989/14/2/100
9. “Unraveling the Evolutionary Diet Mismatch and Its Contribution to the Deterioration of Body Composition”
by Sandi Assaf, Jason Park, Naveed Chowdhry, Meghasree Ganapuram, Shelbin Mattathil, Rami Alakeel and Owen J. Kelly
Metabolites 2024, 14(7), 379; https://doi.org/10.3390/metabo14070379
Available online: https://www.mdpi.com/2218-1989/14/7/379
10. “Obesity in Pregnancy as a Risk Factor in Maternal and Child Health—A Retrospective Cohort Study”
by Miriam Orós, Marta Lorenzo, María Catalina Serna, Júlia Siscart, Daniel Perejón and Blanca Salinas-Roca
Metabolites 2024, 14(1), 56; https://doi.org/10.3390/metabo14010056
Available online: https://www.mdpi.com/2218-1989/14/1/56
Special Issues:
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“Obesity and Metabolic Health” |
“Advancements in Reproductive Medicine: Unlocking the Secrets of the Ovary and Sperm for Fertility and Beyond” |
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“Energy Metabolism in Neurodegenerative Diseases” |
“Metabolic Programming of Hepatic Organ Function—2nd Edition” |
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“Metabolism in Kidney Disease” |
“Primary Hyperparathyroidism: Mechanisms and Treatment” |
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“Metabolic Syndrome in Polycystic Ovary Syndrome” |
“Research on Biomarkers for Cardiometabolic Risk in Metabolic Syndrome” |
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