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Chemistry Proceedings, Volume 14, Issue 1

ECSOC 2023 2023 - 115 articles

The 27th International Electronic Conference on Synthetic Organic Chemistry

Online | 15–30 November 2023

Volume Editor: Julio A. Seijas, Universidade de Santiago de Compostela, Spain

Cover Story: The Electronic Conferences on Synthetic Organic Chemistry (ECSOC) have been hosting a series of online conferences since 1997, thanks to the original initiative by MDPI and later with the valuable contribution of the University of Santiago de Compostela (Spain). This volume compiles all the presentations from the 27th International Electronic Conference on Synthetic Organic Chemistry, held virtually from November 15 to 30, 2023. In addition to organic synthesis, it also covers various topics such as bioorganic chemistry, medicinal and natural product chemistry, microwave-assisted synthesis, polymer and supramolecular chemistry, and computational chemistry. The remarkable participation in this conference has solidified its position as the longest-running event in Internet history, serving as an invaluable platform for researchers across multiple countries.
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Articles (115)

  • Proceeding Paper
  • Open Access
799 Views
4 Pages

Green and Eco-Friendly Multicomponent Synthesis of 2-Hydroxypyridines Under Free Solvent Conditions

  • Djamila Benzenine,
  • Fatima Belhadj,
  • Zahira Kibou,
  • M. Pilar Vázquez-Tato,
  • Julio A. Seijas and
  • Noureddine Choukchou-Braham

17 November 2023

2-Hydroxypyridines (or commonly named 2-pyridones) are widespread nitrogen heterocycles in natural and synthetic products and their applications in biological, pharmaceutical and agrochemical compounds are becoming increasingly important. Therefore,...

  • Proceeding Paper
  • Open Access
878 Views
5 Pages

Multicomponent, Solvent-Free Synthesis of 4-Substituted Aminopyrido[2,3-d]pyrimidines Derivatives

  • Fatima Belhadj,
  • Zahira Kibou,
  • Julio A. Seijas,
  • Maria Pilar Vázquez-Tato and
  • Noureddine Choukchou-Braham

15 November 2023

4-substituted aminopyrido [2,3-d]pyrimidines derivatives 1a–f were synthesized via the multicomponent reaction of 2-aminopyridines, triethyl orthoformate, and diverse primary amines under solvent-free conditions. The present work creates a vari...

  • Proceeding Paper
  • Open Access
1,312 Views
5 Pages

Synthesis and Reactivity of 2-Acetylthiophenes Derivatives

  • Hadjer Missoum,
  • Yazid Datoussaid,
  • Noureddine Choukchou-braham,
  • Julio A. Seijas and
  • Maria Pilar Vázquez-Tato

15 November 2023

Thiophene is a five-membered sulfur containing a heteroaromatic ring. Its presence in compounds of therapeutic interest is remarkable, leading to various studies to develop strategies to synthesize new biologically active thiophene analogues. Due to...

  • Proceeding Paper
  • Open Access
908 Views
5 Pages

Synthesis and Characterization of New 3-Cyano-2-Pyridone Derivatives as Fluorescent Scaffolds

  • Asmaa Kebaili,
  • Fatima Belhadj,
  • Zahira Kibou,
  • Julio A. Seijas,
  • M. Pilar Vazquez Tato and
  • Noureddine Choukchou-Braham

15 November 2023

2-pyridones are among the most widely used nitrogen-containing heterocyclic derivatives in various fields due to their structural properties and biological and therapeutic activities. Therefore, their synthesis has become a major focus of organic che...

  • Proceeding Paper
  • Open Access
1,031 Views
4 Pages

Pyridine Derivatives as Fluorescent Sensors for Cations

  • Ikram Baba-Ahmed,
  • Zahira Kibou,
  • Julio A. Seijas,
  • Ridha Hassaine,
  • Fatiha Nouali,
  • M. Pilar Vázquez-Tato and
  • Noureddine Choukchou-Braham

15 November 2023

A fluorescence grating sensor based on a pyridine derivative was synthesized. The results showed that it can rapidly identify and detect toxic heavy metal ions, such as Cr2+, Hg2+, Ni2+ and Co2+. When these toxic heavy metal ions were added to the fl...

  • Proceeding Paper
  • Open Access
1,415 Views
6 Pages

One-Pot Synthesis of Tetrazole–Triazole Bis-Heterocycles via Ugi–Azide Reaction

  • Fidel Rodriguez-Lopez,
  • Carlos Zárate-Hernández,
  • Manuel A. Rentería-Gómez and
  • Rocío Gámez-Montaño

15 November 2023

Bioisosteres of amide bonds such as 4,5-disubstituted-1,2,3-triazoles (4,5-DS-1,2,3-Ts) and 1,5-disubstituted tetrazoles (1,5-DST) are present in compounds with important biological activities like those that are antineoplastic, antibacterial, antifu...

  • Proceeding Paper
  • Open Access
993 Views
5 Pages

Organocatalytic Properties of 3,4-Dihydroxyprolines

  • Ramón J. Estévez,
  • Rosalino Balo,
  • Andrés Fernández and
  • Juan C. Estévez

15 November 2023

The synthesis and organocatalytic properties of (2S,3R,4R)-3,4-bis((tert-butyldimethylsilyl)oxy)pyrrolidine-2-carboxylic acid are reported. Using the aldol condensation of cyclohexanone with p-nitrobenzaldehyde as a model, a yield of 86%, an enantiom...

  • Proceeding Paper
  • Open Access
1,942 Views
18 Pages

Biological Docking and BSA Binding Studies of 1,4-Disubstituted Piperdine Containing 1,2,4-Triazoles: Comparative Synthesis Leveraging Microwave-Assisted and Conventional Protocols

  • Javed Iqbal,
  • Naeem Akhtar Virk,
  • Aziz Ur Rehman,
  • Aleksey Kuznetsov,
  • Shahid Rasool,
  • Muhammad Yasir and
  • Syed Adnan Ali Shah

15 November 2023

A biologically effective study regarding the synthesis of a library of hybrids based on a triazole ring, propanamide and azinane was performed in this study. The targeted hybrids, 9a–9l, were synthesized through a multistep protocol followed by...

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Chem. Proc. - ISSN 2673-4583Creative Common CC BY license