Chemistry Proceedings, Volume 3, Issue 1

(2E)-3-(3,4-Dichlorophenyl)-N-arylprop-2-enanilides were designed as potential bioactive agents. Six compounds were mono- and di-chlorinated also on the anilide ring. Since the biological activities of molecules are influenced by lipophilicity, the h...

Polyphenols are attracting increasing attention in the discovery of useful agents for the treatment of neurodegenerative diseases. Thelesperma megapotamicum (Spreng.) Kuntze belongs to the family Asteraceae, which is known to have a high antioxidant...

Limonium brasiliense (Boiss.) Kuntze (Plumbaginaceae) is a medicinal plant that is popularly used in the folk medicine. In this study, we examined xanthine oxidase (XO) inhibitory activity of the aqueous fraction of Limonium brasiliense extract and i...

Organophosphorus compounds play an important role in the medicinal- or agricultural industry, and in the human body as well. Over the last years, heterocyclic phosphonates have received growing interest due to their potential biological activity. An...

An efficient and sustainable copper-catalyzed protocol has been developed for the preparation of amidines via nucleophilic addition of amines into nitriles. The reaction proceeded smoothly at 100 °C in the presence of CuCl, Cs2CO3, and 2,2/-bipyridin...

2,4,6-Trichloro-1,3,5-triazine (TCT) offers the unique ability to undergo sequential nucleophilic substitution reactions using regular nucleophiles (first Cl replacement at 0 °C, second at RT, and third at >90 °C), making s-triazine a privileged s...

Iminosugars are sugar mimetics present in plants and microorganisms that were first reported in the 1960s. [...]

The presence of tetrahydropyrans and other sized oxacycles in natural products with interesting pharmacological properties has prompted researchers to try to develop new strategies for their selective synthesis. Moreover, these methodologies enable t...

It has been found that usnic acid carbonyl groups can be hydrogenated by the action of H2/Pd(C). Thus, two new dibenzofuran derivatives were synthesized.

The sensing behavior of a calix[4]arene-oxacyclophane-carbazole conjugate (1) towards Cu(I) ions was investigated. Contrary to the noteworthy sensitivity and selectivity previously found for Cu(II), the affinity of 1 for Cu(I) cations is much lower....