Large-scale low earth orbit (LEO) satellite constellation projects are increasingly adopting inter-satellite links (ISLs) to enable their autonomous and collaborative operation. Due to the large number of satellite constellation network nodes and the...
Uranium, a cornerstone for nuclear energy, facilitates a clean and efficient energy conversion. In the era of global clean energy initiatives, uranium resources have emerged as a vital component for achieving sustainability and clean power. To fulfil...
BDS-3 faces challenges in achieving precision orbit determination (POD) due to the difficulty of establishing a globally uniform distribution of independently operated ground tracking stations. The use of onboard BDS-3 observations collected by low E...
Islatravir is a novel nucleoside reverse transcriptase translocation inhibitor recently approved for the treatment of HIV-1 infection in virologically suppressed PLWH. While we previously documented high-level phenotypic resistance to islatravir (ISL...
Cost- and time-intensive porcine translational disease models offer great opportunities to test drugs and therapies for pathological cardiac hypertrophy and can be supported by porcine cell culture models that provide further insights into basic dise...
Background: Uveal melanoma (UM) represents the most prevalent primary intraocular malignancy in adults, yet patients harboring GNAQ/GNA11 mutations face particularly poor prognoses with median survival of merely 6–12 months following metastasis...
Genetic factors play a critical role in the development of human diseases. Recently, several molecular genetic studies have provided multiple lines of evidence for a critical role of genetic factors in the expression of human bladder exstrophy-epispa...
Tetralogy of Fallot (TOF) is the most common cyanotic congenital heart disease in newborns. ISL1 is a master transcription factor in second heart field development, whereas the roles of ISL1 gene promoter variants in TOF patients have not been geneti...
The LIM homeodomain transcription factor ISL1 is essential for the different aspects of neuronal development and maintenance. In order to study the role of ISL1 in the auditory system, we generated a transgenic mouse (Tg) expressing Isl1 under the Pa...
The Isle of Man is a large island which lies in the middle of the northern Irish Sea between Britain and Ireland and, because of its insularity and size, has an impoverished flora compared with the two main islands. This has been the case throughout...
There is concern regarding the amount of fruit and vegetables consumed and high sugar intakes in children’s diets. Regional dietary differences in the British Isles could underlie variations in health outcomes, but little is known about these differe...
Unconsolidated sandstone uranium deposits exploited by the in situ leaching (ISL) method, contain complex tetravalent and hexavalent uranium compounds, mostly as UO2 and UO3 oxides that have different dissolution rates in sulfuric acid solutions. Thi...
Patients with triple-negative breast cancer have few therapeutic strategy options. In this study, we investigated the effect of isoliquiritigenin (ISL) on the proliferation of triple-negative breast cancer cells. We found that treatment with ISL inhi...
Islatravir (ISL) is the first-in-class nucleoside reverse transcriptase translocation inhibitor (NRTtI) with novel modes of action. Data on ISL resistance are currently limited, particularly to HIV-1 non-B subtypes. This study aimed to assess prevale...
Inter-satellite links (ISLs) can improve the performance of the Global Navigation Satellite System (GNSS) in terms of precise orbit determination, communication, and data-exchange capabilities. This research aimed to evaluate a simulation-based proce...
2,2′,4,4′-Tetrabrominated biphenyl ether (BDE-47) is a polybrominated diphenyl ether (PBDE) homologue that is ubiquitous in biological samples and highly toxic to humans and other organisms. Prior research has confirmed that BDE-47 can in...
Sign language is a visual language for communication used by hearing-impaired people with the help of hand and finger movements. Indian Sign Language (ISL) is a well-developed and standard way of communication for hearing-impaired people living in In...
The Isles of Scilly are an archipelago of islands in the far southwest of the UK which contain numerous beds of wild bivalve molluscs which are recreationally harvested for local consumption. However, the islands have never previously been assessed f...
Theperformanceoftheglobalnavigationsatellitesystem(GNSS)canbeenhancedsignificantly by introducing the inter-satellite links (ISL) of a navigation constellation. In particular, the improvement of the position, velocity, and time accuracy, and the reali...
Inter-Satellite Link (ISL) technology in GNSS constellations improves Monitoring and Control (M&C), data dissemination, and accuracy of ODTS products. ISL-enabled networks can distribute data via Single (SH) or Multiple Hop (MH) routing logics: t...
The 27 September 2021 damaging mainshock (Mw6.0) is the first known strong earthquake that ruptured the Arkalochori area, Crete Isl., Greece, during the entire historical period, making it an unexpected event in the long-term sense. The area is chara...
When analyzing tumors by histopathology, endocrine pathologists have traditionally been restricted to a few key immunohistochemical markers related to secretory vesicles in order to pinpoint neuroendocrine differentiation—most notably Chromogranin A...
Sign languages are important for the deaf and hard-of-hearing communities, as they provide a means of communication and expression. However, many people outside of the deaf community are not familiar with sign languages, which can lead to communicati...
Harbinger elements are DNA transposons that are widespread from plants to vertebrates but absent from mammalian genomes. Among vertebrates, teleost fish are the clade presenting not only the largest number of species but also the highest diversity of...
Background: Bereavement is an inevitable event that can cause pain, discomfort, and negative consequences in daily life. Spirituality and religiosity can help people cope with loss and bereavement. Sometimes, however, the death of a loved one can cha...
This study presents an integrated geophysical and hydrogeological characterization of fault systems in the sandstone-hosted uranium deposit within the K1b2 Ore Horizon of the Bayin Gobi Basin. Employing 3D seismic exploration with 64-fold coverage an...
In global navigation satellite systems (GNSS), the system time reference is maintained by the ground control segment and kept traceable to UTC, enabling inter-system compatibility and interoperability. Advances in onboard atomic-clock stability and i...
Satellite communication is inevitable due to the Internet of Everything and the exponential increase in the usage of smart devices. Satellites have been used in many applications to make human life safe, secure, sophisticated, and more productive. Th...
The integration of sign language recognition systems into digital platforms has the potential to bridge communication gaps between the deaf community and the broader population. This paper introduces an advanced Israeli Sign Language (ISL) recognitio...
The fossil burrower bug Eocenocydnus lisi described from the Late Eocene of the Isle of Wight, UK, is analysed using a parallel, cross-eyed viewing method. The species, tentatively placed in the subfamily Sehirinae, is redescribed and its systematic...
This paper describes the design and principle of operation of a 20 m laser strainmeter of unequal-arm type created on the basis of a Michelson interferometer and frequency-stabilized helium–neon laser. The interferometry methods used allow the...
The medieval British Isles were marked by a lively monastic presence throughout the entire period. Groups of monks, nuns, regular canons and canonesses, and friars established communities even in the furthermost reaches of the territory, and by doing...
Low and Medium Earth Orbit (LEO/MEO) satellite constellations have emerged as a compelling architectural paradigm for delivering multipurpose services. In this study, we investigate the joint optimization of communication and positioning performance...
This Special Issue of Birds is focused on a number of ways in which people and birds interact with nature, and the example discussed here incorporates four of the seven relationships noted. These are: how birds and birding connect people with nature,...
Deploying deep learning segmentation models on embedded hardware requires reducing their numerical precision through quantization, an optimization whose aim is not to improve segmentation quality but to preserve it while reducing latency and energy c...
This study aims to recover, interpret and analyse the early meteorological observations made in Venice by Bernardino Zendrini from 1738 to 1743. Zendrini used a cistern barometer, an Amontons-type air thermometer and an additional mercury thermometer...
Centring on embodiment, gendered eco-spiritual responses to nature, enchantment and environmental crises in the Anthropocene, this paper explores engagement with nature as a spiritual experience and resource through ‘Celtic’ Christian pra...
Solar irradiance is a critical factor influencing the reliability of optical inter-satellite links (O-ISLs). Despite its significance, limited research has focused on addressing this challenge. This work investigates the impact of solar irradiation o...
The segmentation of abnormal regions is vital in smart manufacturing. The blurring sauce-packet leakage segmentation task (BSLST) is designed to distinguish the sauce packet and the leakage’s foreground and background at the pixel level. Howeve...
With the maturation of reusable launch vehicle technology and satellite mass-production capabilities, global mega-constellation projects have entered a phase of rapid expansion. Inter-satellite networking is a key approach for enhancing constellation...
This paper presents the results of geomorphological investigations carried out on the Lilas River fan delta in central Evia Isl., Greece. A geomorphological map has been prepared using Digital Elevation Model analysis, aerial photos and Google Earth...
Over one-third of the Earth’s population resides or works within 200 km of the coast. The increasing threat of coastal hazards with predicted climate change will impact many global citizens. Coastal dune systems serve as a natural first line of...
Moose (Alces alces) are generalist herbivores, but are important aquatic-terrestrial ecotone specialists. Aquatic macrophytes are a high-quality food source for moose during summer, but the importance of aquatic food sources to the moose diet is diff...
Accurate and automated segmentation of ischemic stroke lesions from magnetic resonance imaging (MRI) data is crucial for rapid clinical diagnosis, treatment planning, and patient prognosis. This study presents a comprehensive evaluation of various de...
In next-generation Low-Earth-Orbit (LEO) satellite networks, securing inter-satellite communication links (ISLs) through strong authentication is essential due to the network’s dynamic and distributed structure. Traditional authentication syste...
This paper presents a new energy–economy system modelling approach, developed specifically for energy system planning in non-interconnected islands, aiming for decarbonization. Energy system planning is an essential tool to shape the energy tra...
Architects’ approach towards colour in architectural design evolved radically in the recent 50 years, and ranges from a modernist aversion to a vernacular appreciation. These changes were linked to the development of culture, technology and sci...
A smart city application has been realized and tested. It is a fully remote controlled isle of lamp posts based on new technologies. It has been designed and organized in different hierarchical layers, which perform local activities to physically con...
Ischaemic stroke constitutes a leading cause of global disability. Rapid extraction of the infarct core from multimodal computed tomography perfusion (CTP) imaging guides reperfusion therapy and clinical decision-making. Deep learning algorithms auto...
Merkel cell carcinoma (MCC) is an uncommon malignancy of the skin arising from cells located in the deeper layers of the epidermis called Merkel cells. This malignancy rarely presents as a metastatic disease, and the field is therefore deficient in r...
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