There are presented the generalized results of studies of performance degradation of hydrogen sensors based on MISFET with structure Pd-Ta2O5-SiO2-Si. It was shown how responses’ parameters change during long-term tests of sensors under repeated hydr...
We present the generalized experimental results of performance degradation of hydrogen sensors based on metal-insulator-semiconductor field effect transistor (MISFET)with the structure Pd-Ta2O5-SiO2-Si. The n-channel MISFET elements were fabricated o...
Flexible roofs are sensitive to wind actions because they are light, and their deformability can induce local or global instability. In most cases, their design requires experimental wind tunnel testing to investigate the aeroelastic phenomena and th...
In humans, age-associated degrading changes, widely observed in molecular and cellular processes underly the time-dependent decline in spatial navigation, time perception, cognitive and psychological abilities, and memory. Cross-talk of biological, c...
Chromate has been shown to dysregulate epigenetic mechanisms such as DNA methylation, leading to changes in gene expression and genomic instability. However, most in vitro studies are limited to short incubation periods, although chronic exposure may...
Weakly consolidated sandstone reservoirs in the Bohai region are susceptible to sand production and wellbore instability during high-water-cut production because water–rock interaction progressively degrades rock strength while reservoir deplet...
Piezoelectric energy harvesters can transform the mechanical strain into electrical energy. The microelectromechanical transformation device is often composed of piezoelectric cantilevers and has been largely experimented. Most resonances have been d...
Rock slopes involved in extensive landslide processes are often characterized by complex morphodynamics acting at different scales of space and time, responsible for different evolutionary scenarios. Mass Rock Creep (MRC) is a critical process for lo...
The stability of underground building foundations in fractured rock masses is a critical concern in geotechnical engineering, particularly for urban projects situated in complex geological settings. In such environments, the interaction between weak...
Curcumin (CUR) is a natural compound with anticancer potential; however, its poor water solubility, instability, and rapid degradation limit its therapeutic use. To address these issues, we developed CUR-loaded nanoparticles (CUR-NPs) based on chitos...
Reversine is a small-molecule Aurora kinase inhibitor known for its pro-apoptotic effects and potential to remodel chromatin architecture. Although its impact on mitotic regulation is established, its effects on telomere dynamics and nuclear organiza...
Outcomes for patients following major peripheral nerve injury are extremely poor. Despite advanced microsurgical techniques, the recovery of function is limited by an inherently slow rate of axonal regeneration. In particular, a time-dependent deteri...
Cognitive fatigability is the time-dependent destabilization of cognitive performance under sustained demand and is distinct from subjective fatigue. Neurophysiological effects may persist after demand. To link performance instability during demand w...
Background: Genomic instability, a hallmark of cancer, leads to copy number variations disrupting gene dosage balance and contributing to tumor progression. One of the most affected oncogenes is MYC, whose overexpression is tightly regulated to avoid...
To address the insufficient damping and instability tendency of metal coil spring isolators subjected to intense impact loading, a multi-stage vibration isolation configuration integrating polyurethane, springs, and eddy current dampers is proposed....
Transforming growth factor-β (TGF-β) signaling plays a central role in lung tissue homeostasis, coordinating epithelial repair, immune resolution, and stromal remodeling following injury. However, persistent or dysregulated TGF-β activ...
Tennis requires the integration of physiological, technical, and cognitive abilities during intermittent high-intensity exercise; however, it remains unclear whether tennis-specific exercise induces different acute responses from duration-matched hig...
Siphon vertical axial-flow pump systems are widely used in large-scale low-head pumping stations, irrigation and drainage projects, urban flood control, and water diversion engineering, where safe and stable operation is essential for hydraulic syste...
Today, time-varying delays may result from a communication network’s engagement in frequency control services. These delays have an impact on the effectiveness of the load frequency control (LFC) system, which can occasionally lead to power sys...
While the estimation of the critical velocity for fluidelastic instability of tube arrays has received considerable attention for decades, the studies intended to analyze the post-stable behavior have been scarce. However, the behavior of the system...
The ability to predict the expected internal behaviour of a given solid-propellant rocket motor under transient conditions is important. Research towards predicting and quantifying undesirable transient axial combustion instability symptoms typically...
Incremental subsidence induced by sequential longwall panel extraction is associated with panel interaction and progressive instability of the disturbed rock mass. However, the governing mechanisms and the coupled effects of panel and pillar geometri...
In this paper periodic and quasi-periodic behavior of a food chain model with three trophic levels are studied. Michaelis-Menten type ratio-dependent functional response is considered. There are two equilibrium points of the system. It is found out t...
The models of excitation of quasiperiodic ELF/VLF emissions with spectral shape repetition periods from 10 to 300 s are discussed. The primary cause of quasiperiodic (QP) emissions is cyclotron instability of electron radiation belts. Relatively slow...
Li-rich Mn-based layered oxides are promising cathodes for high-specific-energy lithium-ion batteries because they combine high reversible capacity with relatively abundant manganese. Their capacity advantage originates from coupled cationic–an...
The management of irrigation main canals are studied in this research. One way of improving this is designing an efficient automatic control system of the water that flows through the canal pools, which is usually carried out by PI controllers. Howev...
Metabolic reprogramming and genomic instability are key hallmarks of cancer, the combined analysis of which has gained recent popularity. Given the emerging evidence indicating the role of oncometabolites in DNA damage repair and its routine use in b...
Hierarchical Reinforcement Learning (HRL) is effective for long-horizon and sparse-reward tasks by decomposing complex decision processes, but its real-world application remains limited due to instability between levels, inefficient subgoal schedulin...
The stability of surface gas extraction boreholes in longwall-mining-disturbed zones is constrained by instability driven by mining-induced overburden movement, yet the stage-dependent evolution of overburden displacement fields under large mining he...
Second-order Ordinary Differential Equations (ODEs) with discontinuous forcing have numerous applications in engineering and computational sciences. The analysis of the solution spaces of non-homogeneous ODEs is difficult due to the complexities in m...
Background: Large language models (LLMs) are increasingly used for musculoskeletal health information, yet their safety in time-sensitive shoulder and elbow presentations with red-flag features remains insufficiently defined. We evaluated safety beha...
The Mediterranean region is affected by considerable daily and seasonal temperature variations due to intense solar radiation. In mid-seasons, thermal excursions can exceed tens of degrees thus influencing the long-term behaviour of jointed rock mass...
Friction-induced unstable vibration caused by nonlinear stator–rotor friction and electromechanical coupling is a critical dynamic stability issue in aircraft electric braking systems, potentially degrading braking performance and operational s...
Communication is increasingly present for managing and controlling critical infrastructures strengthening their cyber interdependencies. In electric power systems, grid splitting is a topical communication-critical application. It amounts to separati...
The European Union is increasingly confronted with a convergence of sustainability, democratic, and security-related challenges that affect the conditions for long-term transformation. While sustainable development and democratic resilience are often...
Results from a pilot program to assess boundary mixing processes along the northern continental slope of the Gulf of Mexico are presented. We report a novel attempt to utilize a turbulence flux sensor on a conventional mooring. These data document ma...
Ovarian cancer is one of the most common causes of death in women as survival is highly dependent on the stage of the disease. Ovarian cancer is typically diagnosed in the late stage due to the fact that in the early phases is mostly asymptomatic. Ge...
Checkpoint kinase 1 (Chk1) is a key mediator of the DNA damage response that regulates cell cycle progression, DNA damage repair, and DNA replication. Small-molecule Chk1 inhibitors sensitize cancer cells to genotoxic agents and have shown preclinica...
Piled floating pontoons are public access structures that provide a link between land and sea. Despite floating pontoons being frequented by the public, there is limited data available to coastal or maritime engineers detailing the dynamic motions (a...
Background: Prolonged intermittent fasting is associated with metabolic and immune adaptation; however, the extent to which transcriptional immune responses translate into systemic inflammatory changes, and how these processes relate to autophagy, se...
Tailings dam safety is a cornerstone of green and sustainable mine development. The instability of such facilities directly threatens the safety of surrounding ecosystems, human lives, and property, contravening the Sustainable Development Goals rega...
The induction of T cell-mediated immunity is crucial in vaccine development. The most effective vaccine is likely to employ both cellular and humoral immune responses. The efficacy of a vaccine depends on T cells activated by antigen-presenting cells...
Histone H2AX plays a crucial role in molecular and cellular responses to DNA damage and in the maintenance of genome stability. It is downstream of ataxia telangiectasia mutated (ATM) damage signaling pathway and there is an emerging role of the tran...
In this study, we aimed to evaluate the cellular response of healthy human fibroblasts induced by different types of ultra-low-fluence radiations, including gamma rays, neutrons and high linear energy transfer (LET) heavy ions. NB1RGB cells were pret...
Decentralized agricultural gasification remains constrained by the thermochemical instability of high-alkali residues, such as straw and stalks. This operational bottleneck is defined by a narrow thermal window: oxidation core temperatures are typica...
In the context of deep mining and green low-carbon transition, this study characterizes the thermo-mechanical evolution and fracture mechanisms of cemented tailings backfill (CTB) through systematic experiments conducted at 20–60 °C across...
The asymptotical properties of a special dynamic two-person game are examined under best-response dynamics in both discrete and continuos time scales. The direction of strategy changes by the players depend on the best responses to the strategies of...
This study proposes a mathematical framework for predicting complete response-time distributions associated with parametric video-game configurations. Each configuration is encoded as a point in a normalized metric space, and the statistical descript...
Modelling for very fast transients (VFTs) requires good knowledge of the behaviour of gas insulated substation (GIS) components when subjected to high frequencies. Modelling usually takes the form of circuit-based insulation coordination type studies...
Replication fork stalling generates a variety of responses, most of which cause an increase in single-stranded DNA. ssDNA is a primary signal of replication distress that activates cellular checkpoints. It is also a potential source of genome instabi...
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