The Interplay Between Nutrition, Fasting, and Metabolic Health
A special issue of Nutrients (ISSN 2072-6643). This special issue belongs to the section "Nutrition and Metabolism".
Deadline for manuscript submissions: 20 May 2026 | Viewed by 9
Special Issue Editor
Interests: fasting; gut microbiota; environmental health
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
This Special Issue, "The Interplay Between Nutrition, Fasting, and Metabolic Health," focuses on the synergistic effects of different fasting patterns and nutritional factors, thoroughly exploring their mechanisms and impacts on metabolic regulation. We will systematically investigate various fasting strategies—including intermittent fasting (time-restricted eating and alternate-day fasting), periodic fasting (5:2 diet and fasting-mimicking diet), and prolonged fasting—with particular emphasis on how these dietary patterns influence body health through nutritional pathways such as nutrient metabolism, energy balance, and gut microbiota.
Key nutritional topics of interest include the following:
- Metabolic adaptation mechanisms of macronutrients under different fasting regimens;
- Interactive effects of dietary patterns and fasting cycles on metabolic flexibility;
- Synergistic role of specific nutrients (e.g., polyphenols and dietary fiber) in metabolic regulation during fasting periods;
- Combined effects of fasting and nutritional interventions on metabolic syndrome-related parameters (body composition, glucose homeostasis, and lipid profile).
We welcome human studies across different life stages, physical activity levels, and metabolic backgrounds, including observational studies, randomized controlled trials, systematic reviews, and mechanistic investigations. By integrating the intersecting fields of nutritional science and fasting research, this issue aims to provide theoretical foundations and practical guidance for precision nutrition interventions.
Dr. Robin Mesnage
Guest Editor
Manuscript Submission Information
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Keywords
- prolonged fasting
- intermittent fasting
- metabolic health
- nutrient metabolism
- time-restricted eating
- dietary patterns
- gut microbiota
- muscle preservation
- lipid metabolism
- insulin sensitivity
- low-caloric intake
- inflammatory markers
- mitochondrial function
- clinical outcomes
- energy metabolism
- weight loss
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