Lung Diseases: From Cellular and Molecular Mechanisms to Targeted Therapies

A special issue of Cells (ISSN 2073-4409).

Deadline for manuscript submissions: 31 March 2026 | Viewed by 57

Special Issue Editors


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Guest Editor
Department of Internal Medicine V-Pulmonology, Allergology, Respiratory and Environmental Medicine, Saarland University, 66424 Homburg, Germany
Interests: airway diseases
Special Issues, Collections and Topics in MDPI journals

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Guest Editor
Experimental Pharmacology, Center for Molecular Signaling (PZMS), School of Medicine, Saarland University, 66421 Homburg, Germany
Interests: airway diseases

Special Issue Information

Dear Colleagues,

Lung diseases such as pneumonia, asthma, chronic obstructive pulmonary disease (COPD), idiopathic pulmonary fibrosis and cystic fibrosis affect hundreds of millions of people worldwide, profoundly affecting quality of life and substantially contributing to mortality. Impaired lung function is central to these conditions, typically resulting from a pathogenesis involving acute and chronic inflammation, tissue destruction and airway remodelling. As many lung diseases are incurable and often fatal, with current therapies primarily offering symptomatic relief, it is crucial to gain a deeper understanding of the underlying cellular and molecular mechanisms of these diseases.

Emerging technologies, including 3D organoid cultures, single-cell sequencing, spatial transcriptomics and single-cell epigenomics, now offer unparalleled opportunities to analyse disease pathways and reveal new therapeutic targets. By bridging the gap between fundamental biology and clinical application, these approaches offer great potential for developing mechanism-based therapies.

We invite authors to contribute their work to this Special Issue, “Lung Diseases: From Cellular and Molecular Mechanisms to Targeted Therapies”. We welcome original research articles, reviews and methodological studies that enhance our understanding of the complexity of airway diseases. Topics may include, but are not limited to, the mechanisms driving inflammation, tissue destruction, airway remodelling and therapies. Submissions with clear translational relevance are particularly encouraged.

Prof. Dr. Christoph Beisswenger
Prof. Dr. Daniela Yildiz
Guest Editors

Manuscript Submission Information

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Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • lung diseases
  • cellular and molecular mechanisms
  • targeted therapies
  • OMICS
  • single-cell sequencing

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Published Papers

This special issue is now open for submission.
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