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161 Results Found

  • Article
  • Open Access
31 Citations
7,310 Views
12 Pages

Evaluating a Machine Learning Tool for the Classification of Pathological Uptake in Whole-Body PSMA-PET-CT Scans

  • Annette Erle,
  • Sobhan Moazemi,
  • Susanne Lütje,
  • Markus Essler and ,
  • Thomas Schultz and
  • Ralph A. Bundschuh
  • + 1 author+ 0 author

29 July 2021

The importance of machine learning (ML) in the clinical environment increases constantly. Differentiation of pathological from physiological tracer-uptake in positron emission tomography/computed tomography (PET/CT) images is considered time-consumin...

  • Article
  • Open Access
47 Citations
6,203 Views
11 Pages

Machine Learning Facilitates Hotspot Classification in PSMA-PET/CT with Nuclear Medicine Specialist Accuracy

  • Sobhan Moazemi,
  • Zain Khurshid,
  • Annette Erle,
  • Susanne Lütje and ,
  • Markus Essler,
  • Thomas Schultz and
  • Ralph A. Bundschuh
  • + 2 authors+ 0 author

Gallium-68 prostate-specific membrane antigen positron emission tomography (68Ga-PSMA-PET) is a highly sensitive method to detect prostate cancer (PC) metastases. Visual discrimination between malignant and physiologic/unspecific tracer accumulation...

(This article belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)
  • Article
  • Open Access
20 Citations
4,673 Views
29 Pages

Adipose Tissue-Derived Extracellular Vesicles Contribute to Phenotypic Plasticity of Prostate Cancer Cells

  • Allison Mathiesen,
  • Bronson Haynes,
  • Ryan Huyck,
  • Michael Brown and
  • Anca Dobrian

Metastatic prostate cancer is one of the leading causes of male cancer deaths in the western world. Obesity significantly increases the risk of metastatic disease and is associated with a higher mortality rate. Systemic chronic inflammation can resul...

(This article belongs to the Special Issue Exosomes in Cancer Diagnosis and Therapy 2.0)
  • Review
  • Open Access
58 Citations
17,073 Views
42 Pages

13 February 2025

Malware has emerged as a significant threat to end-users, businesses, and governments, resulting in financial losses of billions of dollars. Cybercriminals have found malware to be a lucrative business because of its evolving capabilities and ability...

(This article belongs to the Section Internet of Things)
  • Article
  • Open Access
5 Citations
3,452 Views
16 Pages

Predicting Response to [177Lu]Lu-PSMA Therapy in mCRPC Using Machine Learning

  • Kaiyuan Gong,
  • Baptiste Magnier,
  • Salomé L’hostis,
  • Fanny Borrely and ,
  • Sébastien Le Bon,
  • Nadine Houede,
  • Adel Mamou,
  • Laurent Maimoun,
  • Pierre Olivier Kotzki and
  • Vincent Boudousq
  • + 5 authors+ 0 author

23 October 2024

Background/Objectives: Radioligandtherapy (RLT) with [177Lu]Lu-PSMA has been newly introduced as a routine treatment for metastatic castration-resistant prostate cancer (mCRPC). However, not all patients can tolerate the entire therapeutic sequence,...

(This article belongs to the Section Omics/Informatics)
  • Article
  • Open Access
84 Citations
5,866 Views
21 Pages

Immunomodulatory, Antioxidant Activity and Cytotoxic Effect of Sulfated Polysaccharides from Porphyridium cruentum. (S.F.Gray) Nägeli

  • Virginia Casas-Arrojo,
  • Juan Decara,
  • María de los Ángeles Arrojo-Agudo,
  • Claudia Pérez-Manríquez and
  • Roberto T. Abdala-Díaz

24 March 2021

Porphyridium cruentum is a unicellular microalga that can synthesize and secrete to the culture medium-high amounts of polysaccharides. In this study, the immunomodulatory, cytotoxic effect and antioxidant activity of the sulfated polysaccharides (Pc...

  • Article
  • Open Access
14 Citations
4,561 Views
12 Pages

Effect of Water Storage on Hardness and Interfacial Strength of Resin Composite Luting Agents Bonded to Surface-Treated Monolithic Zirconia

  • Emmanouil-George Tzanakakis,
  • Maria Dimitriadi,
  • Ioannis Tzoutzas,
  • Petros Koidis and ,
  • Spiros Zinelis and
  • George Eliades
  • + 1 author+ 0 author

4 July 2021

Background: Durable bonding between resin composite luting agents (CLA) and zirconia is still a matter of controversy. The purpose of this study was to evaluate the effect of water storage on hardness and interfacial strength of three CLA, a non-adhe...

(This article belongs to the Topic Advances in Dental Biomaterials and Oral Tissues Engineering)
  • Article
  • Open Access
1 Citations
1,186 Views
13 Pages

Production, Purification, and Application of a Biomolecule with Herbicidal Activity Produced by Fusarium fujikuroi in Submerged Cultivation

  • Silvana Schmaltz,
  • Clair Walker,
  • Keli Souza da Silva,
  • Renata Gulart Ninaus and ,
  • Cláudia Braga Dutra,
  • Luiza Andrea Schmidt,
  • Gilson Zeni and
  • Marcio Antonio Mazutti
  • + 3 authors+ 0 author

This study investigated the production, purification, and evaluation of a microbial metabolite with herbicidal activity produced by Fusarium fujikuroi via submerged fermentation. The purified compound (PC) was obtained through organic solvent extract...

(This article belongs to the Special Issue 10th Anniversary of Fermentation: Feature Papers in Section "Industrial Fermentation")
  • Article
  • Open Access
10 Citations
2,857 Views
22 Pages

Antimicrobial and Mycotoxin Reducing Properties of Lactic Acid Bacteria and Their Influence on Blood and Feces Parameters of Newborn Calves

  • Paulina Zavistanaviciute,
  • Modestas Ruzauskas,
  • Ramunas Antanaitis,
  • Mindaugas Televicius and ,
  • Vita Lele,
  • Antonello Santini and
  • Elena Bartkiene
  • + 2 authors+ 0 author

27 October 2023

The aim of this study was to evaluate the influence of in acid whey (AW) multiplied Lactiplantibacillus plantarum LUHS135 (L.pl135), Lacticaseibacillus paracasei LUHS244 (L.pc244), and their biomass combination on newborn calves’ feces and bloo...

(This article belongs to the Section Animal Nutrition)
  • Article
  • Open Access
1 Citations
845 Views
4 Pages

Protein C System in Patients with Idiopathic Pulmonary Fibrosis—Preliminary Report

  • Anna Kiziewicz,
  • Ewa Żekanowska,
  • Krzysztof Cieśliński and
  • Krzysztof Góralczyk

22 June 2008

Introduction: The natural anticoagulant—activated protein C system plays an important role in the pathogenesis of idiopathic pulmonary fibrosis. The purpose of this study was to evaluate the concentration of protein C (PC), protein S (PS), thrombomod...

  • Proceeding Paper
  • Open Access
1 Citations
2,201 Views
7 Pages

10 November 2020

The application of medium-chain triglycerides (MCT) in food items can pave the way for its increased utilization and for consumers to avail of its benefits. Preliminary studies have indicated that soymilk enrichment with MCT requires the application...

(This article belongs to the Proceedings of The 1st International Electronic Conference on Food Science and Functional Foods)
  • Article
  • Open Access
17 Citations
4,487 Views
15 Pages

Targeted Metabolomics Analysis on Obstructive Sleep Apnea Patients after Multilevel Sleep Surgery

  • Abdulmohsen Alterki,
  • Shibu Joseph,
  • Thangavel Alphonse Thanaraj,
  • Irina Al-Khairi and ,
  • Preethi Cherian,
  • Arshad Channanath,
  • Devarajan Sriraman,
  • Mahmoud A. K. Ebrahim,
  • Alaaeldin Ibrahim and
  • Mohamed Abu-Farha
  • + 9 authors+ 4 authors

1 September 2020

Background: Obstructive sleep apnea (OSA) is caused by partial or complete obstruction of the upper airways. Corrective surgeries aim at removing obstructions in the nasopharynx, oropharynx, and hypopharynx. OSA is associated with an increased risk o...

(This article belongs to the Section Metabolomic Profiling Technology)
  • Proceeding Paper
  • Open Access
220 Views
11 Pages

The use of post-consumer scrap (PCS) in aluminium structural components is a challenging but important strategy for reducing carbon footprint in the automotive industry. However, introducing PCS increases uncertainty and compositional variation, whic...

(This article belongs to the Proceedings of The 16th International Aluminium Conference)
  • Feature Paper
  • Article
  • Open Access
3 Citations
4,517 Views
26 Pages

5 February 2025

The self-administration of meloxicam via medicated feed is a novel concept that could enable non-invasive, pre-emptive and long-term analgesia. Forty Bos taurus male calves were randomly allocated to four treatment groups: no castration (PC), surgica...

(This article belongs to the Special Issue Developments in Therapeutic Drugs for Pain Management in Animals)
  • Communication
  • Open Access
14 Citations
3,485 Views
11 Pages

Mutation Analysis of Pancreatic Juice and Plasma for the Detection of Pancreatic Cancer

  • Iris J. M. Levink,
  • Maurice P. H. M. Jansen,
  • Zakia Azmani,
  • Wilfred van IJcken and ,
  • Ronald van Marion,
  • Maikel P. Peppelenbosch,
  • Djuna L. Cahen,
  • Gwenny M. Fuhler and
  • Marco J. Bruno
  • + 4 authors+ 0 author

23 August 2023

Molecular profiling may enable earlier detection of pancreatic cancer (PC) in high-risk individuals undergoing surveillance and allow for personalization of treatment. We hypothesized that the detection rate of DNA mutations is higher in pancreatic j...

(This article belongs to the Special Issue Pancreatic Disease: From Molecular Basis to Novel Therapies)
  • Article
  • Open Access
19 Citations
5,325 Views
14 Pages

Phytoremediation of PAH- and Cu-Contaminated Soil by Cannabis sativa L.: Preliminary Experiments on a Laboratory Scale

  • Ilaria Gabriele,
  • Francesco Bianco,
  • Marco Race,
  • Stefano Papirio and
  • Giovanni Esposito

18 January 2023

This study proposes the phytoremediation of phenanthrene (PHE)-, pyrene (PYR)-, and copper (Cu)-contaminated soil by Cannabis sativa L. The experimental campaign was conducted in 300 mL volume pots over a 50 d period using different initial polycycli...

(This article belongs to the Section Pollution Prevention, Mitigation and Sustainability)
  • Article
  • Open Access
1 Citations
929 Views
27 Pages

Immunological Mechanisms and Machine Learning Applications in Post-COVID-19 Syndrome: A Narrative Review

  • Leonid P. Churilov,
  • Anna Starshinova,
  • Igor Kudryavtsev,
  • Artem Rubinstein and ,
  • Olesya Koroteeva,
  • Anastasia Kulpina,
  • Varvara A. Ryabkova,
  • Adilya Sabirova,
  • Polina Sobolevskaia and
  • Dmitry Kudlay
  • + 6 authors+ 1 author

Post-COVID-19 syndrome (PCS), also referred to as post-acute sequelae of SARS-CoV-2 infection (PASC), represents a heterogeneous set of persistent clinical manifestations developing after acute infection. These conditions are associated with immune d...

(This article belongs to the Special Issue Coronavirus: Epidemiology, Diagnosis, Pathogenesis and Control)
  • Article
  • Open Access
22 Citations
3,247 Views
22 Pages

Photocatalytic, Antimicrobial, and Cytotoxic Efficacy of Biogenic Silver Nanoparticles Fabricated by Bacillus amyloliquefaciens

  • Ahmed M. Eid,
  • Saad El-Din Hassan,
  • Mohammed F. Hamza,
  • Samy Selim and ,
  • Mohammed S. Almuhayawi,
  • Mohammed H. Alruhaili,
  • Muyassar K. Tarabulsi,
  • Mohammed K. Nagshabandi and
  • Amr Fouda
  • + 4 authors+ 0 author

30 June 2024

The biomass filtrate of the endophytic bacterial strain Bacillus amyloliquefaciens Fa.2 was utilized for the eco-friendly production of silver nanoparticles (Ag-NPs). The yellowish-brown color’s optical properties showed a maximum surface plasm...

(This article belongs to the Special Issue Applications and New Trends in Catalysts and Photocatalytic Nanomaterials for Environmental Remediation)
  • Article
  • Open Access
70 Views
28 Pages

Optimization of Phycocyanin Production from Arthrospira platensis: Response Surface Modeling and FTIR Characterization

  • Josue Duarte-Cuesta,
  • Diego Barzallo,
  • Samuel Valle-Asan,
  • Rafael Lazo-Sulca and ,
  • Samanta Benavides-Villarreal,
  • Gustavo Vaca-Triviño and
  • Miguel Reinoso-Sanchez
  • + 2 authors+ 0 author

10 November 2026

Arthrospira platensis provides a cyanobacterial source of C-phycocyanin (C-PC). We evaluated 15 Box–Behnken experimental runs across 13 distinct factor combinations, varying NaHCO3 addition (5–20 g L−1), illuminance (3500–9500...

(This article belongs to the Special Issue Rational Design and Optimization of Catalysts for Biomass Valorization)
  • Article
  • Open Access
45 Citations
3,935 Views
13 Pages

Procyanidins Alleviated Cerebral Ischemia/Reperfusion Injury by Inhibiting Ferroptosis via the Nrf2/HO-1 Signaling Pathway

  • Lei Chen,
  • Jie Huang,
  • Zi-Meng Yao,
  • Xiao-Rong Sun and ,
  • Xu-Hui Tong,
  • Miao Hu,
  • Ying Zhang and
  • Shu-Ying Dong
  • + 3 authors+ 0 author

20 April 2023

Procyanidins (PCs), which are organic antioxidants, suppress oxidative stress, exhibit anti−apoptotic properties, and chelate metal ions. The potential defense mechanism of PCs against cerebral ischemia/reperfusion injury (CIRI) was investigate...

  • Article
  • Open Access
29 Citations
7,444 Views
16 Pages

Evidence of Protein Adsorption in Pegylated Liposomes: Influence of Liposomal Decoration

  • Marc Sangrà,
  • Joan Estelrich,
  • Raimon Sabaté,
  • Alba Espargaró and
  • Maria Antònia Busquets

10 February 2017

In order to contribute to a better knowledge of the events involved in the formation of the protein corona when nanoparticles (NPs) come in contact with proteins, we report a study about the changes on the physicochemical properties of pristine, PEGy...

  • Article
  • Open Access
32 Citations
5,989 Views
15 Pages

HPLC-DAD Determination of Nitrite and Nitrate in Human Saliva Utilizing a Phosphatidylcholine Column

  • Małgorzata Tatarczak-Michalewska,
  • Jolanta Flieger,
  • Justyna Kawka,
  • Wojciech Płaziński and ,
  • Wojciech Flieger,
  • Eliza Blicharska and
  • Dariusz Majerek
  • + 2 authors+ 0 author

The aim of this research was to optimize the separation and quantitative determination of nitrites and nitrates in human saliva. HPLC with UV absorption (HPLC/DAD) using a phosphatidylcholine column (IAM.PC.DD2 Regis HPLC) was applied in this assay....

(This article belongs to the Section Analytical Chemistry)
  • Article
  • Open Access
7 Citations
3,594 Views
28 Pages

29 September 2023

Pancreatic cancer (PC) has one of the lowest survival rates among all major types of cancer. Consequently, it is one of the leading causes of mortality worldwide. Serum biomarkers historically correlate well with the early prognosis of post-surgical...

(This article belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)
  • Article
  • Open Access
52 Citations
6,538 Views
22 Pages

Developing a Simulated Online Model That Integrates GNSS, Accelerometer and Weather Data to Detect Parturition Events in Grazing Sheep: A Machine Learning Approach

  • Eloise S. Fogarty,
  • David L. Swain,
  • Greg M. Cronin,
  • Luis E. Moraes and ,
  • Derek W. Bailey and
  • Mark Trotter
  • + 1 author+ 0 author

25 January 2021

In the current study, a simulated online parturition detection model is developed and reported. Using a machine learning (ML)-based approach, the model incorporates data from Global Navigation Satellite System (GNSS) tracking collars, accelerometer e...

(This article belongs to the Section Animal System and Management)
  • Article
  • Open Access
3 Citations
2,714 Views
18 Pages

Anthelmintic-Like Activity and Ultrastructure Changes Produced by Two Polyphenolic Combinations against Cooperia punctata Adult Worms and Infective Larvae

  • Elke von Son-de Fernex,
  • Estefanía Zúñiga-Olivos,
  • Luis Felipe Jiménez-García and
  • Pedro Mendoza-de Gives

Cooperia punctata is one of the most prevalent gastrointestinal nematodes affecting cattle under grazing conditions, and the increasing reports of anthelmintic resistance forces researchers to look for novel control measures. Previous reports have pr...

(This article belongs to the Section Parasitic Pathogens)
  • Article
  • Open Access
1 Citations
928 Views
12 Pages

Analysis of Operator Expertise in MRI/TRUS Fusion-Guided Prostate Biopsy

  • Rouvier Al-Monajjed,
  • Lars Schimmöller,
  • Jale Lakes,
  • Anna Herzum and ,
  • Anne Hübner,
  • Isabelle Bußhoff,
  • Tim Ullrich,
  • Alexandra Ljimani,
  • Irene Esposito and
  • Matthias Boschheidgen
  • + 8 authors+ 3 authors

28 November 2025

Background/Objectives: This study analyzed the impact of operator experience on the detection of PC and csPC using a standardized MRI/TRUS-fusion biopsy protocol in an experienced high-volume center. Methods: Men with mpMRI and subsequent combined TB...

(This article belongs to the Section Cancer Causes, Screening and Diagnosis)
  • Article
  • Open Access
21 Citations
8,220 Views
18 Pages

Evaluation of Machine Learning Algorithms for Early Diagnosis of Deep Venous Thrombosis

  • Eduardo Enrique Contreras-Luján,
  • Enrique Efrén García-Guerrero,
  • Oscar Roberto López-Bonilla,
  • Esteban Tlelo-Cuautle and ,
  • Didier López-Mancilla and
  • Everardo Inzunza-González
  • + 1 author+ 0 author

Deep venous thrombosis (DVT) is a disease that must be diagnosed quickly, as it can trigger the death of patients. Nowadays, one can find different ways to determine it, including clinical scoring, D-dimer, ultrasonography, etc. Recently, scientists...

(This article belongs to the Special Issue Numerical and Evolutionary Optimization 2021)
  • Article
  • Open Access
1,133 Views
23 Pages

Integrating GWAS and Machine Learning to Dissect the Genetic Basis of Flowering Time and Vernalization-Type Differentiation in Brassica napus

  • Ye Hua,
  • Zhen Huang,
  • Xiaoyue Zhu,
  • Ruixin Zhang and ,
  • Lei Gong,
  • Haiqing Liu and
  • Yongjun Shu
  • + 2 authors+ 0 author

Flowering time is an important trait affecting regional adaptation and yield stability in rapeseed (Brassica napus). To dissect the genetic basis of flowering time and vernalization-type differentiation in B. napus, this study integrated genome-wide...

(This article belongs to the Special Issue Application of Machine Learning in Horticultural Production)
  • Article
  • Open Access
2 Citations
1,491 Views
25 Pages

The presence of sea ice threatens low ice-class vessels’ navigation safety in the Arctic, and traditional Navigation Risk Assessment Models based on sea ice parameters have been widely used to guide safe passages for ships operating in ice regi...

(This article belongs to the Section Ocean Engineering)
  • Article
  • Open Access
1,651 Views
19 Pages

Distribution and Phylogenetic Diversity of Synechococcus-like Cyanobacteria in the Late Autumn Picophytoplankton of the Kara Sea: The Role of Atlantic and Riverine Water Masses

  • Tatiana A. Belevich,
  • Irina A. Milyutina,
  • Andrey B. Demidov,
  • Olga V. Vorob’eva and ,
  • Alexander A. Polukhin,
  • Sergey A. Shchuka and
  • Aleksey V. Troitsky
  • + 2 authors+ 0 author

22 August 2025

Increased Atlantic water transport and river discharge are more pronounced effects of global warming at high latitudes. Both phenomena may lead to changes in the species composition of small-celled algae populations in marine ecosystems, as well as t...

(This article belongs to the Section Plant Systematics, Taxonomy, Nomenclature and Classification)
  • Article
  • Open Access
21 Citations
3,787 Views
11 Pages

Infectivity and Morphology of Bovine Coronavirus Inactivated In Vitro by Cationic Photosensitizers

  • Vladimir Zhukhovitsky,
  • Natalia Shevlyagina,
  • Margarita Zubasheva,
  • Leonid Russu and ,
  • Vladimir Gushchin,
  • Gennady Meerovich and
  • Marina Strakhovskaya
  • + 2 authors+ 0 author

15 May 2022

Bovine coronaviruses (BCoVs), which cause gastrointestinal and respiratory diseases in cattle, and are genetically related to the human coronavirus HCoV-OC43, which is responsible for up to 10% of common colds, attract increased attention. We applied...

(This article belongs to the Special Issue Viruses Research in Russia 2022)
  • Article
  • Open Access
1 Citations
1,198 Views
11 Pages

Liquid Trisilanol i-Octyl POSS Achieves Rapid Hemostasis and Pneumostasis in Experimental Lung Injury

  • Michelle Tucci,
  • Robert C. O′Brien,
  • Joseph D. Lichtenhan,
  • Hamed Benghuzzi and
  • Drew Hildebrandt

Background/Objectives: No effective intervention currently exists for non-compressible pulmonary injury, especially in a prehospital setting. Visco-liquids like trisilanol i-octyl POSS could remedy this. POSS resists hemorrhage and activates clotting...

  • Article
  • Open Access
1 Citations
1,443 Views
18 Pages

Cytoimmunological Profile of Lower Airways in Post-COVID-19 Syndrome (PCS): Predictive Value of Bronchoalveolar Lavage

  • Justyna Dolna-Michno,
  • Piotr Kopiński,
  • Grzegorz Przybylski,
  • Ewa Wypasek and ,
  • Magdalena Szymańska,
  • Ewelina Wędrowska,
  • Klaudia Mikołajczyk,
  • Tomasz Senderek and
  • Maciej Gagat
  • + 4 authors+ 0 author

12 May 2025

Background: It has yet to be determined whether the immunocytological profile of the bronchoalveolar lavage (BAL) in respiratory post-COVID syndrome (PCS) reflects the risk of persistent interstitial lung disease (ILD), including pulmonary fibrosis....

(This article belongs to the Special Issue Novel Insights into COVID-19-Associated Complications and Sequelae)
  • Article
  • Open Access
30 Citations
6,752 Views
13 Pages

Sub-ppb Level Detection of BTEX Gaseous Mixtures with a Compact Prototype GC Equipped with a Preconcentration Unit

  • Irene Lara-lbeas,
  • Alberto Rodríguez-Cuevas,
  • Christina Andrikopoulou,
  • Vincent Person and ,
  • Lucien Baldas,
  • Stéphane Colin and
  • Stéphane Le Calvé
  • + 2 authors+ 0 author

13 March 2019

In this work, a compact gas chromatograph prototype for near real-time benzene, toluene, ethylbenzene and xylenes (BTEX) detection at sub-ppb levels has been developed. The system is composed of an aluminium preconcentrator (PC) filled with Basolite...

(This article belongs to the Special Issue Gas Flows in Microsystems)
  • Article
  • Open Access
13 Citations
4,415 Views
13 Pages

30 April 2021

The study was conducted to investigate the effects of replacing antibiotic growth promoters (AGPs) with an egg immunoglobulin (IgY) combined with phytomolecules (PM) on the growth rate, serum immunity, and intestinal health of weaned pigs challenged...

(This article belongs to the Special Issue Feeding Strategies to Minimize the Use of Antimicrobials and Zinc Oxide in Pig Production)
  • Article
  • Open Access
176 Views
21 Pages

Procyanidin Protects Against Polystyrene Microplastic-Induced Male Reproductive Injury Through the NRF2/SLC7A11/GPX4 Pathway

  • Shihui Zhang,
  • Qiang Shan,
  • Boshi Xu,
  • Shuo Li and ,
  • Zheng Cao,
  • Yanan Li and
  • Lijia Zhao
  • + 2 authors+ 0 author

27 October 2026

Polystyrene microplastics (PS-MPs) are ubiquitous environmental contaminants of emerging concern owing to their potential adverse effects on male reproductive health. However, the mechanisms underlying PS-MP-induced reproductive injury remain poorly...

(This article belongs to the Section Animal Reproduction)
  • Article
  • Open Access
17 Citations
4,644 Views
13 Pages

13 October 2022

The efficacy of Moringa oleifera seed extract (MSE) in broiler nutrition is unknown. Thus, this study evaluated the effect of administering MSE through drinking water on physiological responses, carcass and meat quality traits, and bone parameters in...

(This article belongs to the Section Food Science and Technology)
  • Article
  • Open Access
2 Citations
1,167 Views
9 Pages

Association between Asthma Control Test, Pulmonary Function Tests and Non-Specific Bronchial Hyperresponsiveness in Assessing the Level of Asthma Control

  • Iwona Florentyna Grzelewska-Rzymowska,
  • Joanna Mikołajczyk,
  • Jadwiga Kroczyńska-Bednarek and
  • Paweł Górski

Introduction: Global Initiative for Asthma (GINA) reports emphasize the use of validated and simple tools in order to assess the level of asthma control, as the Asthma Control Test (ACT). However, an ACT does not include assessment of airway inflamma...

  • Article
  • Open Access
31 Citations
4,484 Views
11 Pages

The Photosensitizer Octakis(cholinyl)zinc Phthalocyanine with Ability to Bind to a Model Spike Protein Leads to a Loss of SARS-CoV-2 Infectivity In Vitro When Exposed to Far-Red LED

  • Kirill Sharshov,
  • Mariya Solomatina,
  • Olga Kurskaya,
  • Ilya Kovalenko and ,
  • Ekaterina Kholina,
  • Vladimir Fedorov,
  • Gennady Meerovich,
  • Andrew Rubin and
  • Marina Strakhovskaya
  • + 4 authors+ 0 author

9 April 2021

Photodynamic inactivation of pathogenic microorganisms can be successfully used to eradicate pathogens in localized lesions, infected liquid media, and on various surfaces. This technique utilizes the photosensitizer (PS), light, and molecular oxygen...

(This article belongs to the Special Issue State-of-the-Art Respiratory Viruses Research in Russia)
  • Article
  • Open Access
1 Citations
3,786 Views
18 Pages

Electrospray Beta-Glucan Particle Coated PVP/CA Electrospun Mat as a Potential Scaffold for Dental Tissue Regeneration

  • Thanutham Somboonchokephisal,
  • Pratchaya Tipduangta,
  • Sarawut Kumphune and
  • Tanida Srisuwan

5 October 2025

Regenerative endodontic procedures (REPs) are a promising treatment for immature teeth with pulpal necrosis. However, the outcomes remain unpredictable, partly due to scaffold limitations. Beta-glucan (BG), a bioactive polysaccharide with regenerativ...

(This article belongs to the Section Biobased and Biodegradable Polymers)
  • Article
  • Open Access
7 Citations
2,380 Views
13 Pages

Combination of the Topical Photodynamic Therapy of Chloroaluminum Phthalocyanine Liposomes with Fexinidazole Oral Self-Emulsifying System as a New Strategy for Cutaneous Leishmaniasis Treatment

  • Raphaela Ariany Silva,
  • Danielle Soter Damasio,
  • Larissa Dutra Coelho,
  • Eliane de Morais-Teixeira and ,
  • Celso M. Queiroz-Junior,
  • Paulo Eduardo Souza,
  • Ricardo Bentes Azevedo,
  • Antônio Tedesco,
  • Lucas Antônio Ferreira and
  • Marta Gontijo Aguiar
  • + 6 authors+ 1 author

Cutaneous leishmaniasis (CL) is a neglected tropical disease. The treatment is restricted to drugs, such as meglumine antimoniate and amphotericin B, that exhibit toxic effects, high cost, long-term treatment, and limited efficacy. The development of...

(This article belongs to the Special Issue Advanced Liposomes for Drug Delivery, 2nd Edition)
  • Article
  • Open Access
3 Citations
1,873 Views
12 Pages

An experimental study by the Paul-Ehrlich Institute (PEI) demonstrated that temperatures between 35 and 37 °C are too high for the growth of some bacterial strains (e.g., Pseudomonas fluorescens), leading to false negative results. Thus, the ques...

(This article belongs to the Special Issue Safety of Platelet Components: Past, Present and Future)
  • Article
  • Open Access
4 Citations
6,125 Views
13 Pages

A Novel PAA Derivative with Enhanced Drug Efficacy in Pancreatic Cancer Cell Lines

  • Ali Alsuraifi,
  • Paul Kong Thoo Lin,
  • Anthony Curtis,
  • Dimitrios A. Lamprou and
  • Clare Hoskins

22 September 2018

Nanoparticles have been shown to be effective drug carriers in cancer therapy. Pancreatic cancer forms dense tumours which are often resistant to drug molecules. In order to overcome such multidrug resistance, new drug entities, novel delivery system...

(This article belongs to the Special Issue Nano Drug Carriers)
  • Article
  • Open Access
22 Citations
5,906 Views
15 Pages

Quality Parameters of Wheat Bread with the Addition of Untreated Cheese Whey

  • Charikleia Tsanasidou,
  • Ioanna Kosma,
  • Anastasia Badeka and
  • Michael Kontominas

11 December 2021

Τhe present study was carried out to evaluate wheat bread of three different flour compositions prepared by replacing water with untreated cheese whey (WCB). Bread prepared with water was taken as the control (CB). All breads were stored at 24 &p...

(This article belongs to the Section Food Chemistry)
  • Article
  • Open Access
6 Citations
3,727 Views
12 Pages

ML216-Induced BLM Helicase Inhibition Sensitizes PCa Cells to the DNA-Crosslinking Agent Cisplatin

  • Xiao-Yan Ma,
  • Jia-Fu Zhao,
  • Yong Ruan,
  • Wang-Ming Zhang and ,
  • Lun-Qing Zhang,
  • Zheng-Dong Cai and
  • Hou-Qiang Xu
  • + 2 authors+ 0 author

12 December 2022

Using standard DNA-damaging medicines with DNA repair inhibitors is a promising anticancer tool to achieve better therapeutic responses and reduce therapy-related side effects. Cell viability assay, neutral comet assay, western blotting (WB), and cel...

  • Article
  • Open Access
21 Citations
3,672 Views
14 Pages

30 January 2023

Activity monitoring has become a necessary demand for weak people to guarantee their safety. The paper proposed a Parallel Training Logical Execution (PTLE) system using machine learning (ML) models on a microelectromechanical system (MEMS) accelerom...

(This article belongs to the Section Wearables)
  • Article
  • Open Access
16 Citations
5,729 Views
18 Pages

Enrichment of 3D-Printed k-Carrageenan Food Gel with Callus Tissue of Narrow-Leaved Lupin Lupinus angustifolius

  • Kseniya Belova,
  • Elena Dushina,
  • Sergey Popov,
  • Andrey Zlobin and ,
  • Ekaterina Martinson,
  • Fedor Vityazev and
  • Sergey Litvinets
  • + 2 authors+ 0 author

6 January 2023

The aim of the study is to develop and evaluate the printability of k-carrageenan inks enriched with callus tissue of lupin (L. angustifolius) and to determine the effect of two lupin calluses (LA14 and LA16) on the texture and digestibility of 3D-pr...

(This article belongs to the Special Issue Recent Developments in Food Gels)
  • Article
  • Open Access
7 Citations
4,015 Views
17 Pages

How Attention Changes in Response to Carbohydrate Mouth Rinsing

  • Thomas J. Hosang,
  • Sylvain Laborde,
  • Andreas Löw,
  • Michael Sprengel and ,
  • Niels Baum and
  • Thomas Jacobsen
  • + 1 author+ 0 author

6 July 2023

Research investigating the effects of carbohydrate (CHO) mouth rinsing on neurocognitive functions is currently limited and has yielded inconsistent results. In this study, we employed the event-related potential (ERP) electroencephalography techniqu...

(This article belongs to the Section Sports Nutrition)
  • Article
  • Open Access
1,789 Views
15 Pages

A Dual-Aptamer Electrochemical Sensor for Simultaneous Detection of L-Lactate and Prostate-Specific Antigen

  • Ziheng Hu,
  • Xiaoqian Zhou,
  • Haicheng Song,
  • Fuliang Wei and ,
  • Zhenzhen Li and
  • Lingyan Feng
  • + 1 author+ 0 author

Accurate analysis of prostate cancer (PC)-related biomarkers requires sensing platforms capable of sensitive and multiplex detection in complex biological environments. Herein, we propose a signal-on electrochemical aptamer-based sensor (E-AB) for th...

(This article belongs to the Topic Biomarkers of Disease: Discovery and Clinical Applications)
  • Review
  • Open Access
11 Citations
3,678 Views
22 Pages

Predicting Immunotherapy Efficacy with Machine Learning in Gastrointestinal Cancers: A Systematic Review and Meta-Analysis

  • Sara Szincsak,
  • Péter Király,
  • Gabor Szegvari,
  • Mátyás Horváth and ,
  • David Dora and
  • Zoltan Lohinai
  • + 1 author+ 0 author

Machine learning (ML) algorithms hold the potential to outperform the selection of patients for immunotherapy (ICIs) compared to previous biomarker studies. We analyzed the predictive performance of ML models and compared them to traditional clinical...

(This article belongs to the Special Issue Recent Advances in Gastrointestinal Cancer, 2nd Edition)

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