Background/Objectives: Antinuclear antibody testing by indirect immunofluorescence on HEp-2 cells (ANA-IIF) remains the reference test for systemic autoimmune rheumatic diseases (SARD). However, complete serological characterization requires integrat...
Colonoscopy procedure has been the key screening method to detect colorectal cancer (CRC). As a fatal disease, CRC needs early detection. The COVID-19 pandemic caused screening tests (colonoscopy) to be halted and delayed. As a result, there could be...
A compound collection of pronounced structural diversity was comprehensively screened for inhibitors of the DNA damage-related kinase CK1. The collection was evaluated in vitro. A potent and selective CK1 inhibitor was discovered and its capacity to...
The current study aimed to create an electrostatic window screen to keep stable flies and houseflies out of cattle barns. The screen comprised three identical framed metal nets arranged in parallel at specific intervals. The central net was connected...
Research methods that predict Fe bioavailability for humans can be extremely useful in evaluating food fortification strategies, developing Fe-biofortified enhanced staple food crops and assessing the Fe bioavailability of meal plans that include suc...
Coagulation assays currently employed are often low throughput, require specialized equipment and/or require large blood/plasma samples. This study describes the development, optimization and early application of a generic low-volume and high-through...
Objective: To analyze trends in screening and invasive prenatal diagnosis of chromosome abnormalities (CA) over a 13-year period and correlate them to changes in the national prenatal screening policy. Methods: We retrospectively reviewed Down syndro...
High-throughput screening is a potent technique to accelerate the discovery and development of new materials. By performing massive synthesis and characterization processes in parallel, it can rapidly discover materials with desired components, struc...
Gastrointestinal cancers, especially colorectal cancer, represent a major health care issue. According to the data, the incidence of these cancers exceeds 50/100,000, mainly in high-income countries. Risk factors for the disease include genetic facto...
Influenza is an acute respiratory infection caused by the influenza virus, but few drugs are available for its treatment. Consequently, researchers have been engaged in efforts to discover new antiviral mechanisms that can lay the foundation for nove...
The increase of data collection in various domains calls for an adaptation of methods of visualization to tackle magnitudes exceeding the number of available pixels on screens and challenging interactivity. This growth of datasets size has been suppo...
Thiazole and piperazine are two important heterocyclic rings that play a prominent role in nature and have a broad range of applications in agricultural and medicinal chemistry. Herein, we report the parallel synthesis of a library of diverse piperaz...
Our previous results reported that compared to sickle cell patients who were not screened at birth, those who benefited from it had a lower incidence of a first bacteremia and a reduced number and days of hospitalizations. In this context, this artic...
This review examines the progress of electrostatic spore-trapping research and the potential for the practical application of electrostatic apparatuses in powdery mildew control. These apparatuses produce an electric field by charging an insulated co...
The imidazole-4,5-dicarboxylic acid scaffold is readily derivatized with amino acid esters to afford symmetrically- and dissymmetrically-disubstituted imidazole-4,5-dicarboxamides with intramolecularly hydrogen bonded conformations that predispose th...
In the laser screen velocity measuring (LSVM) system, there is a deviation in the consistency of the optoelectronic response between the start light screen and the stop light screen. When the projectile passes through the light screen, the projectile...
This article presents a novel model for the management of air cargo shipment screening. Previous research has focused solely on making the air cargo screening process as efficient as possible. These scientific papers did not look at the costs generat...
Smartphone industries are seeking to maximize screen size, but a perfect full-screen phone is not yet available due to the unoccupied area required for the mobile antennas. Since a touchscreen is coated with transparent conductive layers, antennas be...
The identification and optimization of electrode materials is of great importance in the study of (flow and solid state) batteries, industrial electrocatalysis and analytical devices such as sensors. To identify useful materials from a virtually unbo...
A simple setup, which is suitable for parallel deposition of homogenous liquids with a precise volume (dosage), is presented. First, liquid is dispensed as an array of droplets onto a superhydrophobic dosage plate, featuring a 3 × 3 array of ho...
Recent osteochondral repair strategies highlight the promise of mesenchymal progenitors, an accessible stem cell source with osteogenic and chondrogenic potential, used in conjunction with biomaterials for tissue engineering. For this, regenerative m...
Background: Patient education materials (PEMS) are frequently used to help patients make cancer screening decisions. However, because PEM are typically developed by experts, they might inadequately address patient barriers to screening. We co-created...
To address the issues of high pod damage rate and unpicked pod rate in the picking device of peanut picking combine harvesters during the harvesting of sun-dried peanuts, a low-damage peanut picking device was developed. This device combines flat pin...
A high-throughput (HT) screening platform developed at hte with the application focus on automotive catalysis is described. hte HT units are configured for performing steady-state testing, as well as dynamic tests with fast feed switches, such as lea...
Sudden onset of anosmia is a phenomenon often associated with developing COVID-19 disease and has even been described as an initial isolated symptom in individual cases. In this case-control study, we investigated the feasibility of this condition as...
The imidazole-4,5-dicarboxylic acid scaffold is readily derivatized with amino acid esters and alkanamines to afford compounds with intramolecularly hydrogen bonded conformations that mimic substituted purines and therefore are hypothesized to be pot...
Amidst growing demand for meat products, concerns regarding their authenticity and safety have intensified, primarily due to potential fraudulent substitutions of cheaper meats, which are not accurately labeled. This study presents a novel strategy f...
Recently expanded reports of multidrug-resistant fungal infections underscore the need to develop new and more efficient methods for antifungal drug discovery. A ubiquitous problem in natural product drug discovery campaigns is the rediscovery of kno...
Although fundus fluorescein angiography (FFA) is a very effective retinal imaging tool for ophthalmic diagnosis, the requirement of intravenous injection of harmful fluorescein dye limits its application. As a screening diagnostic method that reduces...
In this study, the optical refractive constants of the (5, 5) SWBNNT and (5, 5) SWCNT systems were calculated in both parallel and perpendicular directions of the tube axis by using Quantum ESPRESSO and YAMBO code. It also extended the optical behavi...
The aim of this paper is to investigate the geometry of lightlike hypersurfaces in an
Paediatric acute myeloid leukaemia (AML) is a heterogeneous disease characterised by the malignant transformation of myeloid precursor cells with impaired differentiation. Standard therapy for paediatric AML has remained largely unchanged for over fo...
The development of therapeutic interventions for diseases necessitates a crucial step known as drug screening, wherein potential substances with medicinal properties are rigorously evaluated. This process has undergone a transformative evolution, dri...
Screening for genomic sequence variants in genes of predictive and prognostic significance is an integral part of precision medicine. Next-generation sequencing (NGS) technologies are progressively becoming platforms of choice to facilitate this, owi...
The number of remote sensing satellites has increased rapidly in parallel with the advancement of space technology and the rising demand in the space industry. Consequently, the observation effectiveness evaluation of remote sensing satellites has re...
The application of next-generation sequencing (NGS) to characterize cancer genomes has resulted in the discovery of numerous genetic markers. Consequently, the number of markers that warrant routine screening in molecular diagnostic laboratories, oft...
Ante-mortem bovine tuberculosis (bTB) tests for buffaloes include the single comparative intradermal tuberculin test (SCITT), interferon-gamma (IFN-γ) release assay (IGRA) and IFN-γ-inducible protein 10 release assay (IPRA). Although para...
The multiple frequency driving method (MFDM) capacitive touch system (CTS), which drives transmit (TX) electrodes in parallel, has been developed to improve the touch-sensitivity of large touch screens at high speed. However, when driving multiple TX...
The incidence of Severe Combined Immunodeficiency (SCID) in Manitoba, (1/15,000), is at least three to four times higher than the national average and that reported from other jurisdictions. It is overrepresented in two population groups: Mennonites...
How to rapidly and accurately screen bioactive components from complex natural products remains a major challenge. In this study, a screening platform for pancreatic lipase (PL) inhibitors was established by combining magnetic beads-based ligand fish...
Newborn screening for congenital hypothyroidism remains challenging decades after broad implementation worldwide. Testing protocols are not uniform in terms of targets (TSH and/or T4) and protocols (parallel vs. sequential testing; one or two specime...
Analog signals from gas sensors are used to recognize all types of VOC (Volatile Organic Compound) substances, such as toxic gases, tobacco or ethanol. The processes to recognize these substances include acquisition, treatment and machine learning fo...
Extracts of plants from the Malaysian rainforest and other fragile habitats are being researched intensively for identification of beneficial biological actions, with assessment of antioxidant behavior being a common component of such assessments. A...
In 1959, 63 years after the death of John Langdon Down, Jérôme Lejeune discovered trisomy 21 as the genetic reason for Down syndrome. Screening for Down syndrome has been applied since the 1960s by using maternal age as the risk parameter. Since then...
G-quadruplexes (G4s) are of vital biological significance and G4-specific ligands with conformational selectivity show great application potential in disease treatment and biosensing. RHAU, a RNA helicase associated with AU-rich element, exerts biolo...
29 August 2025
Background: Neurocysticercosis (NCC) and HIV co-infection frequently occur in sub-Saharan Africa, yet the accuracy of available serological tests for NCC in immunosuppressed patients is uncertain. Methodology: We performed a cross-sectional diagnosti...
So far, airport security screening has only been analysed in terms of efficiency, level of service, and protection against any acts of unlawful interference. Screening procedures have not yet addressed the need to limit operator-to-passenger contact....
This work provides a method for the development of conductive water-based printing inks for gravure, flexography and screen-printing incorporating commercial resins that are already used in the printing industry. The development of the respective con...
Kinase signaling plays an important role in acquired epilepsy, but only a small percentage of the total kinome has been investigated in this context. A major roadblock that prevents the systematic investigation of the contributions of kinase signalin...
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