Prevention, Early Detection, and Surgical Oncology in Hepatocellular Carcinoma, Pancreatic Cancer, and Gastrointestinal Cancer

A special issue of Cancers (ISSN 2072-6694). This special issue belongs to the section "Cancer Causes, Screening and Diagnosis".

Deadline for manuscript submissions: 30 October 2025 | Viewed by 881

Special Issue Editors


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Guest Editor
Division of Gastroenterology and Hepatology, Department of Internal Medicine, Taipei Medical University—Shuang Ho Hospital, New Taipei City 23561, Taiwan
Interests: hepatitis; hepatocellular carcinoma; gastric cancer

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Guest Editor
Division of Gastroenterology, Department of Internal Medicine, MacKay Memorial Hospital, Taipei 104217, Taiwan
Interests: colorectal adenoma; H. pylori; MASH

Special Issue Information

Dear Colleagues,

Early detection plays a crucial role in improving outcomes in hepatocellular carcinoma (HCC), pancreatic cancer, and gastrointestinal (GI) cancers. Advanced imaging techniques, biomarker testing, and regular surveillance in high-risk populations are essential in identifying these malignancies at an early, more treatable stage. Surgical oncology remains the cornerstone of curative treatment for these cancers. For HCC, liver resection or transplantation offers the best chance of long-term survival when the disease is detected early. Pancreatic cancer, often diagnosed at advanced stages, can be treated with surgical resection combined with neoadjuvant or adjuvant therapies to improve prognosis. In GI cancers, such as colorectal or gastric cancer, minimally invasive surgical techniques and enhanced recovery protocols have significantly improved patient outcomes. Interdisciplinary approaches integrating surgery into targeted therapies and immunotherapy are increasingly important in the management of these cancers. Continued research into early detection methods and precision oncology offers hope in terms of reducing mortality and enhancing quality of life in affected patients.

We are particularly interested in manuscripts that explore early detection and the role of surgery in HCC, pancreatic cancer, and other gastrointestinal cancers.

Dr. Mingyao Chen
Dr. Kuang-Chun Hu
Guest Editors

Manuscript Submission Information

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Keywords

  • early image detection in cancer
  • biomarker of cancer
  • surgical treatment
  • gastrointestinal cancer

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Published Papers (1 paper)

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Review

14 pages, 628 KiB  
Review
Screening in Gastrointestinal Malignancies—Recent Trials and Advancements
by Natalia Czerw, Andrzej Deptała, Anna Badowska-Kozakiewicz, Aleksandra Czerw, Olga Partyka, Monika Pajewska, Katarzyna Sygit, Magdalena Michalska, Izabela Gąska, Grażyna Dykowska, Zofia Sienkiewicz, Elżbieta Grochans, Szymon Grochans, Anna Cybulska, Daria Schneider-Matyka, Ewa Bandurska, Weronika Ciećko, Jaroslaw Drobnik, Piotr Pobrotyn, Joanna Furtak-Pobrotyn, Dagmara Pokorna-Kałwak, Urszula Grata-Borkowska, Michal Marczak, Petre Iltchev and Remigiusz Kozlowskiadd Show full author list remove Hide full author list
Cancers 2025, 17(6), 975; https://doi.org/10.3390/cancers17060975 - 13 Mar 2025
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Abstract
Gastrointestinal cancers, especially colorectal cancer, represent a major health care issue. According to the data, the incidence of these cancers exceeds 50/100,000, mainly in high-income countries. Risk factors for the disease include genetic factors (i.e., Lynch syndrome) and lifestyle factors, e.g., overweight and [...] Read more.
Gastrointestinal cancers, especially colorectal cancer, represent a major health care issue. According to the data, the incidence of these cancers exceeds 50/100,000, mainly in high-income countries. Risk factors for the disease include genetic factors (i.e., Lynch syndrome) and lifestyle factors, e.g., overweight and obesity, smoking tobacco products, low-fiber diet, and low physical activity. When diagnosed early, gastrointestinal cancers can, in most cases, be effectively treated. This review focuses on the presentation of research in the area of screening and its results. It provides insights into current trends in research on methods of early cancer detection and improving screening reporting. Differing levels of screening reporting are one of the main challenges faced by researchers in this field. Research on this issue should be conducted in parallel with research on methods of early diagnosis. Finally, the development of diagnostic methods and communication with patients are important elements of public health. Full article
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