Special Issue "Role and Application of Stem Cells in Regenerative Medicine"
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Pathology, Diagnostics, and Therapeutics".
Deadline for manuscript submissions: 31 August 2019.
Dr. Jacopo Pizzicannella
ASL02 Lanciano-Vasto Chieti, Ss. Annunziata Hospital, Chieti, Italy
Interests: translational medicine; stem cells biology; oral stem cells; regenerative medicine
Mesenchymal stem cells (MSCs) are currently being used in preclinical and clinical trials for their aptitude to promote wound healing and tissue regeneration.
In particular, oral-derived Mesenchymal Stem Cells (oral-MSCs) represent accessible sites available for stem cell collection and they can be used in regenerative medicine, avoiding the ethical concerns. They can be derived from different oral tissues, such as human exfoliated deciduous teeth (SHED), periodontal ligament (PDLSCs), dental follicle progenitor cells (DFPCs), apical papilla (SCAP), dental pulp (DPSCs) and gingival tissue (GMSCs), and posses multipotential, proliferation and differentiation abilities. Moreover, oral-MSCs represent paracrine and immunomodulatory capacity, an innovative tool for the treatment of various degenerative and traumathic processes, including skeletal and maxilla-facial degeneration, trauma or ischemia injuries, neurodegenerative, as well as immune disorders.
This Special Issue, “Role and Application of Stem Cells in Regenerative Medicine”, of the International Journal of Molecular Sciences will comprise a selection of research papers and reviews that will contribute in the evaluation of aptitude, in particular, of oral-MSCs and their secretome in terms of tissue regeneration, as a starting point for the fabrication of 3D-living constructs for future clinical applications.
Moreover, to better understand the molecular mechanisms involved in tissue regeneration, in vitro and in vivo studies will provide a possible high impact in the development of stem cell based regeneration strategies and in the identification of the key biological regulation processes that remain uncovered.
Prof. Dr. Oriana Trubiani
Dr. Jacopo Pizzicannella
Dr. Francesca Diomede
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- Mesenchymal stem cells
- Tissue reggeneration
- Regenerative medicine
- Immunomodulatory process