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236 Results Found

  • Article
  • Open Access
564 Views
14 Pages

This paper proposes improving the dynamic characteristics of a personal mobility device (PMD) battery charger using fuzzy logic control (FLC). Recently, as the use of PMD has expanded, research on the PMD battery charger has also been actively conduc...

(This article belongs to the Section Power Electronics)
  • Article
  • Open Access
17 Citations
3,807 Views
16 Pages

19 February 2021

This paper addresses the validation of a robust vision-based pose estimation technique using a Photonic Mixer Device (PMD) sensor as a single visual sensor in the close-range phase of spacecraft rendezvous. First, it was necessary to integrate the de...

(This article belongs to the Section Sensing and Imaging)
  • Article
  • Open Access
13 Citations
7,993 Views
22 Pages

Close Range Tracking of an Uncooperative Target in a Sequence of Photonic Mixer Device (PMD) Images

  • Ksenia Klionovska,
  • Jacopo Ventura,
  • Heike Benninghoff and
  • Felix Huber

10 January 2018

This paper presents a pose estimation routine for tracking attitude and position of an uncooperative tumbling spacecraft during close range rendezvous. The key innovation is the usage of a Photonic Mixer Device (PMD) sensor for the first time during...

  • Article
  • Open Access
10 Citations
7,649 Views
7 Pages

Thermodynamic Analysis on the Aging of THPP, ZPP and BKNO3 Explosive Charges in PMDs

  • Kyung Min Kim,
  • Sung Il Choi,
  • Ki Heon Eom,
  • Gil Hwan Ahn and ,
  • Jong Gyu Paik,
  • Byung Tae Ryu,
  • Yong Ha Kim and
  • Yong Sun Won
  • + 3 authors+ 0 author

10 January 2019

The aging of explosive charges in pyrotechnic mechanical devices (PMDs) significantly affects the reliability of their performance. Aging decreases the explosive power of explosive charges via pre-oxidation by external sources of oxygen. In this stud...

(This article belongs to the Special Issue Selected Papers from 6th Asian Conference onInnovative Energy & Environmental Chemical Engineering and The 16th Asian Conference on Fluidized‐bed and Three‐phase Reactor (ASCON‐IEEChE 2018))
  • Case Report
  • Open Access
10 Citations
4,123 Views
10 Pages

The Risk of Malignant Degeneration of Müllerian Derivatives in PMDS: A Review of the Literature

  • Federica Gagliardi,
  • Augusto Lauro,
  • Livia De Anna,
  • Domenico Tripodi and ,
  • Anna Esposito,
  • Flavio Forte,
  • Daniele Pironi,
  • Eleonora Lori,
  • Patrizia Alba Gentile and
  • Vito D’Andrea
  • + 7 authors+ 2 authors

25 April 2023

Persistent Müllerian Duct Syndrome (PMDS) is a rare autosomal recessive disorder of sex development characterized by the presence of fallopian tubes, uterus and upper one-third of the vagina in individuals with XY genotype and normal male phenot...

(This article belongs to the Special Issue Innovative Surgical Researches)
  • Article
  • Open Access
2,394 Views
14 Pages

A Wavefront Integration Algorithm Based on Radial Basis Function for Off-Axis PMD

  • Heyan Wang,
  • Dahai Li,
  • Xinwei Zhang,
  • Renhao Ge and
  • Wanxing Zheng

3 January 2023

Sampled points on a measured surface are not evenly spaced on rectangular grids but, rather, have a more general quadrilateral geometry due to the perspective effect of the off-axis configuration, which is extensively utilized in phase measuring defl...

  • Article
  • Open Access
5 Citations
9,496 Views
13 Pages

CMOS Image Sensors and Plasma Processes: How PMD Nitride Charging Acts on the Dark Current

  • Yolène Sacchettini,
  • Jean-Pierre Carrère,
  • Romain Duru,
  • Jean-Pierre Oddou and ,
  • Vincent Goiffon and
  • Pierre Magnan
  • + 1 author+ 0 author

14 December 2019

Plasma processes are known to be prone to inducing damage by charging effects. For CMOS image sensors, this can lead to dark current degradation both in value and uniformity. An in-depth analysis, motivated by the different degrading behavior of two...

(This article belongs to the Special Issue Special issue on the 2019 International Image Sensor Workshop (IISW2019))
  • Article
  • Open Access
537 Views
16 Pages

7 February 2026

This paper proposes a transient response enhancement of a personal mobility device (PMD) battery charger using a rule-based fuzzy logic control (RBFLC) method. PMD encompasses various applications, including electric kickboards, electric scooters, an...

(This article belongs to the Special Issue Advanced Modeling and Design of Vibration and Wave Systems)
  • Article
  • Open Access
879 Views
19 Pages

MSeqDR PMD-VR: An Expert-Curated Virtual Registry of 11,000 Mitochondrial Disease Cases Established Through Literature Mining and Generative AI Augmentation

  • Lishuang Shen,
  • Marie T. Lott,
  • Elizabeth M. Mccormick,
  • Colleen C. Muraresku and ,
  • Kierstin Keller,
  • Douglas C. Wallace,
  • Zarazuela Zolkipli-Cunningham,
  • Shamima Rahman,
  • Marni J. Falk and
  • Xiaowu Gai
  • + 5 authors+ 0 author

30 June 2026

Background/Objectives: Patient registries are essential for rare disease research, yet the extensive genetic and phenotypic heterogeneity of primary mitochondrial diseases (PMDs) makes traditional registry development slow and resource-intensive. We...

(This article belongs to the Special Issue Mitochondrial Genetics in Health and Disease)
  • Article
  • Open Access
3 Citations
4,684 Views
7 Pages

A Combined Study of TEM-EDS/XPS and Molecular Modeling on the Aging of THPP, ZPP, and BKNO3 Explosive Charges in PMDs under Accelerated Aging Conditions

  • Kyung Min Kim,
  • Junwoo Lee,
  • Sung Il Choi,
  • Gil Hwan Ahn and ,
  • Jong Gyu Paik,
  • Byung Tae Ryu,
  • Yong Ha Kim and
  • Yong Sun Won
  • + 3 authors+ 0 author

2 January 2019

The aging mechanism of explosive charges in pyrotechnic mechanical devices (PMDs) is pre-oxidations of their fuels (TiH2 for THPP, Zr for ZPP, and B for BKNO3) by external oxygen. The effect of water on the aging of explosive charges was thus investi...

(This article belongs to the Special Issue Selected Papers from 6th Asian Conference onInnovative Energy & Environmental Chemical Engineering and The 16th Asian Conference on Fluidized‐bed and Three‐phase Reactor (ASCON‐IEEChE 2018))
  • Article
  • Open Access
7 Citations
6,817 Views
11 Pages

Dengue fever is an acute disease caused by the dengue virus and transmitted primarily by the mosquito Aedes aegypti. The current strategy for dengue prevention is vector control including the use of topical repellents to reduce mosquito biting. Altho...

(This article belongs to the Special Issue Integrated Pest Management)
  • Article
  • Open Access
3 Citations
1,906 Views
11 Pages

An Iterative Deflectometry Method of Reconstruction of Separate Specular Surfaces

  • Cheng Liu,
  • Jianhua Liu,
  • Yanming Xing,
  • Xiaohui Ao and ,
  • Hongda Shen and
  • Chunguang Yang
  • + 1 author+ 0 author

2 March 2025

Phase measuring deflectometry (PMD) plays a more and more significant role in the measurement of specular surfaces. However, most of the deflectometric methods are only suitable for continuous specular surfaces, but not for the discontinuous surfaces...

(This article belongs to the Section Optical Sensors)
  • Article
  • Open Access
5 Citations
4,901 Views
15 Pages

Background: We developed a novel polymer insect repellent conjugate for extended release and decreased skin permeation of the volatile insect repellent p-menthane-3,8-diol (PMD). Methods: PMD was conjugated with acryloyl chloride via an ester bond to...

(This article belongs to the Section Drug Targeting and Design)
  • Article
  • Open Access
23 Citations
4,747 Views
14 Pages

24 October 2019

Phase-measuring deflectometry (PMD)-based methods have been widely used in the measurement of the three-dimensional (3D) shape of specular objects, and the existing PMD methods utilize visible light. However, specular surfaces are sensitive to ambien...

(This article belongs to the Section Optical Sensors)
  • Review
  • Open Access
27 Citations
8,817 Views
20 Pages

Mutation of Proteolipid Protein 1 Gene: From Severe Hypomyelinating Leukodystrophy to Inherited Spastic Paraplegia

  • Guy Khalaf,
  • Claudia Mattern,
  • Mélina Begou,
  • Odile Boespflug-Tanguy and ,
  • Charbel Massaad and
  • Liliane Massaad-Massade
  • + 1 author+ 0 author

Pelizaeus–Merzbacher Disease (PMD) is an inherited leukodystrophy affecting the central nervous system (CNS)—a rare disorder that especially concerns males. Its estimated prevalence is 1.45–1.9 per 100,000 individuals in the general...

(This article belongs to the Section Neurobiology and Clinical Neuroscience)
  • Article
  • Open Access
1,294 Views
21 Pages

Association of Mediterranean Diet Scores with Psychological Distress in Pregnancy: The Japan Environment and Children’s Study

  • Yuri Takahashi,
  • Zen Watanabe,
  • Noriyuki Iwama,
  • Natsumi Kumagai and ,
  • Hirotaka Hamada,
  • Hikaru Karumai-Mori,
  • Seiya Izumi,
  • Emi Yokoyama,
  • Yasuno Takahashi and
  • The Japan Environment and Children’s Study Group
  • + 20 authors+ 15 authors

25 November 2025

Background/Objectives: Perinatal mental disorders are important health issues that affect both mothers and their children. The Mediterranean diet (MD) is one of the most well-recognized healthy dietary patterns worldwide. Recent evidence suggests tha...

(This article belongs to the Section Nutrition in Women)
  • Article
  • Open Access
7 Citations
4,393 Views
24 Pages

Oxygraphy Versus Enzymology for the Biochemical Diagnosis of Primary Mitochondrial Disease

  • Matthew J Bird,
  • Isabelle Adant,
  • Petra Windmolders,
  • Ingrid Vander Elst and ,
  • Catarina Felgueira,
  • Ruqaiah Altassan,
  • Sarah C Gruenert,
  • Bart Ghesquière,
  • Peter Witters and
  • Pieter Vermeersch
  • + 6 authors+ 1 author

10 October 2019

Primary mitochondrial disease (PMD) is a large group of genetic disorders directly affecting mitochondrial function. Although next generation sequencing technologies have revolutionized the diagnosis of these disorders, biochemical tests remain essen...

(This article belongs to the Special Issue Genetic Metabolic Diagnostics)
  • Article
  • Open Access
9 Citations
5,210 Views
8 Pages

17 January 2022

Persistent Müllerian duct syndrome (PMDS) is a rare autosomal recessive disorder of sexual development in males, defined by the presence of Müllerian remnants with otherwise normal sexual differentiation. Mutations in anti-Müllerian ho...

(This article belongs to the Special Issue Genetics of Complex Human Disease)
  • Article
  • Open Access
3 Citations
3,234 Views
17 Pages

Modeling the Carbothermal Chlorination Mechanism of Titanium Dioxide in Molten Salt Using a Deep Neural Network Potential

  • Enhao Zhang,
  • Xiumin Chen,
  • Jie Zhou,
  • Huapeng Wu and ,
  • Yunmin Chen,
  • Haiguang Huang,
  • Jianjun Li and
  • Qian Yang
  • + 3 authors+ 0 author

2 February 2025

The molten salt chlorination method is one of the two main methods for producing titanium tetrachloride, an important intermediate product in the titanium industry. To effectively improve chlorination efficiency and reduce unnecessary waste salt gene...

(This article belongs to the Topic AI and Computational Methods for Modelling, Simulations and Optimizing of Advanced Systems: Innovations in Complexity)
  • Article
  • Open Access
2 Citations
1,996 Views
25 Pages

Phase Measuring Deflectometry for Wafer Thin-Film Stress Mapping

  • Yang Gao,
  • Xinjun Wan,
  • Kunying Hsin,
  • Jiaqing Tao and ,
  • Zhuoyi Yin and
  • Fujun Yang
  • + 1 author+ 0 author

18 December 2025

Wafer-level thin-film stress measurement is essential for reliable semiconductor fabrication. However, existing techniques present limitations in practice. Interferometry achieves high precision but at a cost that becomes prohibitive for large wafers...

(This article belongs to the Section Optical Sensors)
  • Article
  • Open Access
7 Citations
4,951 Views
22 Pages

20 December 2020

As a typical application of indirect-time-of-flight (ToF) technology, photonic mixer device (PMD) solid-state array Lidar has gained rapid development in recent years. With the advantages of high resolution, frame rate and accuracy, the equipment is...

(This article belongs to the Section Remote Sensors)
  • Article
  • Open Access
22 Citations
10,143 Views
20 Pages

Range Camera Self-Calibration Based on Integrated Bundle Adjustment via Joint Setup with a 2D Digital Camera

  • Mozhdeh Shahbazi,
  • Saeid Homayouni,
  • Mohammad Saadatseresht and
  • Mehran Sattari

8 September 2011

Time-of-flight cameras, based on Photonic Mixer Device (PMD) technology, are capable of measuring distances to objects at high frame rates, however, the measured ranges and the intensity data contain systematic errors that need to be corrected. In th...

(This article belongs to the Section Physical Sensors)
  • Article
  • Open Access
263 Views
14 Pages

Ameliorative Effects of Citrus Unshiu Peel Extract in Cellular and Mouse Models of Pelizaeus–Merzbacher Disease

  • Miyu Yamamoto,
  • Hideya Sakaguchi,
  • Moeri Yagi,
  • Yuta Muraki and ,
  • Akinori Nishi,
  • Hideji Yako,
  • Junji Yamauchi and
  • Yuki Miyamoto
  • + 3 authors+ 0 author

30 September 2026

Hypomyelinating leukodystrophy 1 (HLD1), also known as Pelizaeus–Merzbacher disease (PMD), is a severe X-linked hereditary hypomyelinating/demyelinating disorder caused primarily by genomic duplications or multiplications that lead to the incre...

(This article belongs to the Special Issue Advanced Studies on Bioactive Natural Products for Human Health)
  • Article
  • Open Access
5 Citations
5,342 Views
21 Pages

17 February 2019

The photonic mixer device (PMD) solid-state array lidar, as a three-dimensional imaging technology, has attracted research attention in recent years because of its low cost, high frame rate, and high reliability. To address the disadvantages of tradi...

(This article belongs to the Special Issue Depth Sensors and 3D Vision)
  • Article
  • Open Access
1 Citations
3,587 Views
29 Pages

Low-Current High-Voltage Pulsed Atmospheric Arc Plasma Jet: Nanoparticle Emission from the Cathodic Spot

  • Dariusz Korzec,
  • Florian Freund,
  • Isabelle Doelfs,
  • Florian Zacherl and ,
  • Lucas Kudala and
  • Hans-Peter Rabl
  • + 1 author+ 0 author

28 October 2025

The atmospheric pressure plasma jet (APPJ) is a popular type of cold atmospheric plasma (CAP). APPJs based on a pulsed atmospheric arc (PAA) are widely spread in industrial processing. A plasma jet of this type, PlasmaBrush PB3 (PB3), is a subject of...

(This article belongs to the Special Issue Feature Papers in Plasma Sciences 2025)
  • Article
  • Open Access
5,567 Views
16 Pages

Small GTP-binding proteins of the Rab family regulate intracellular vesicle trafficking across many aspects of the transport system. Among these, Rab9 is recognized for its role in controlling the transport system not only around the trans-Golgi netw...

  • Article
  • Open Access
9 Citations
3,904 Views
12 Pages

Analysis and Investigation of Dual-Polarized Color LED Based Visible Light Communication System

  • Yun-Cheng Yang,
  • Chien-Hung Yeh,
  • Shien-Kuei Liaw,
  • Chi-Wai Chow and ,
  • Wei-Hung Hsu and
  • Bo-Yin Wang
  • + 1 author+ 0 author

To increase the data capacity of a light-emitting diode (LED) based visible light communication (VLC) transmission, a polarization-division-multiplexing (PMD) green (G)- and blue (B)- light-based transmitter (Tx) module is demonstrated here. It was d...

(This article belongs to the Special Issue Optical Network and Access Technologies)
  • Review
  • Open Access
62 Citations
6,762 Views
19 Pages

28 February 2020

As oral squamous cell carcinoma (OSCC) can develop from potentially malignant disorders (PMDs), it is critical to develop methods for early detection to improve the prognosis of patients. Epithelial–mesenchymal transition (EMT) plays an importa...

(This article belongs to the Special Issue Head and Neck Cancers)
  • Article
  • Open Access
48 Citations
16,068 Views
21 Pages

18 April 2012

In this paper experimental comparisons between two Time-of-Flight (ToF) cameras are reported in order to test their performance and to give some procedures for testing data delivered by this kind of technology. In particular, the SR-4000 camera by Me...

(This article belongs to the Special Issue Time-of-Flight Range-Imaging Cameras)
  • Article
  • Open Access
2 Citations
2,576 Views
13 Pages

The brain changes in response to sensory signals it is exposed to. It has been shown that long term potentiation-like neuroplasticity can be experimentally induced via visual paired-associative stimulation (V-PAS). V-PAS combines afferent visual stim...

(This article belongs to the Special Issue Brain Plasticity and Motor Control—Series II)
  • Article
  • Open Access
7 Citations
3,718 Views
19 Pages

1 December 2020

Considerable efforts are being made to reduce CO2 emissions and thereby solve the problems of environmental pollution and global warming. Technologies for environmentally friendly transportation are being developed using batteries. In particular, wit...

(This article belongs to the Section Power Electronics)
  • Review
  • Open Access
1 Citations
3,243 Views
24 Pages

The progress made in several fields after 2023 is rather significant. Attenuation achieved by the best HCFs was reduced to 0.05–0.10 dB/km at 1550 nm, while the lowest attenuation achieved in a single-mode fiber with a pure silica core equals 0...

(This article belongs to the Special Issue Advances in Hollow-Core Optical Fibers: From Fundamentals to Applications)
  • Brief Report
  • Open Access
4 Citations
2,553 Views
11 Pages

Heightened Procoagulation after Post-Operative Thromboprophylaxis Completion in Patients with Metastatic Bone Disease from Primary Colorectal Cancer

  • Lisa Yamaura,
  • Daniel Young,
  • Leslie Skeith,
  • Michael J. Monument and ,
  • Craig N. Jenne,
  • Antoine Dufour,
  • Prism Schneider and
  • Ejaife O. Agbani
  • + 3 authors+ 0 author

13 December 2022

Background: Platelets play a role in venous thromboembolism (VTE) and in mediating colorectal cancer (CRC) progression. Still, platelets’ role in hypercoagulability after surgical intervention for metastatic bone disease (MBD) is ill-defined. M...

(This article belongs to the Section General Surgery)
  • Article
  • Open Access
878 Views
26 Pages

14 May 2026

The phase transformation characteristics of Sn-Pb-Bi ternary alloys with four representative Bi/Pb mass fraction ratios (0, 0.14, 0.33, and 0.60) were systematically investigated using the deep potential molecular dynamics (DeePMD) method over a temp...

(This article belongs to the Special Issue Application of First Principles and Molecular Dynamics Calculations to Metallic Material Design)
  • Article
  • Open Access
423 Views
34 Pages

PMDS-YOLO: A Lightweight Deep Learning Model for Non-Destructive Citrus Fruit Diameter Estimation and Quality Grading

  • Hang Liu,
  • Zhiyong Cao,
  • Zifei Ma,
  • Binyuan Zhong and ,
  • Siyu Li,
  • Yulin Li,
  • Aiying Yin,
  • Ziyi Yang,
  • Rong Liu and
  • Tong Li
  • + 7 authors+ 2 authors

11 September 2026

Citrus fruit size is a core quality attribute that determines commercial value and market acceptance. In postharvest processing, rapid, accurate, and non-destructive diameter estimation is an essential prerequisite for automated grading, yet existing...

(This article belongs to the Section Food Engineering and Technology)
  • Review
  • Open Access
10 Citations
4,148 Views
25 Pages

Relationships between Cognitive Functioning and Powered Mobility Device Use: A Scoping Review

  • Alice Pellichero,
  • Lisa K. Kenyon,
  • Krista L. Best,
  • Marie-Eve Lamontagne and ,
  • Marie Denise Lavoie,
  • Éric Sorita and
  • François Routhier
  • + 2 authors+ 0 author

Background. Powered mobility devices (PMD) promote independence, social participation, and quality of life for individuals with mobility limitations. However, some individuals would benefit from PMD, but may be precluded access. This is particularly...

(This article belongs to the Section Digital Health)
  • Article
  • Open Access
3 Citations
4,203 Views
16 Pages

The Process of Home-Visiting Nurses Supporting People with Mental Disorders

  • Fumi Ohtake,
  • Maiko Noguchi-Watanabe and
  • Kumiko Morita

The number of people with mental disorders (PMD) living in the community is increasing; however, it is unclear how home-visiting nurses (HVNs) supporting them in the community acquire their support skills. This study aimed to reveal the process of ho...

(This article belongs to the Special Issue Community-Based Mental Health Promotion and Psychosocial Support)
  • Article
  • Open Access
4 Citations
8,664 Views
12 Pages

The Provision of Powered Mobility Devices in Italy: Linking Process with Outcomes

  • Lorenzo Desideri,
  • Devis Trioschi,
  • Roberta Agusto,
  • Martina Bizzarri and ,
  • Gianantonio Spagnolin,
  • Sabrina Cantelli,
  • Caterina Paolini,
  • Massimiliano Malavasi and
  • Claudio Bitelli
  • + 4 authors+ 0 author

The present paper reports on a series of studies conducted at the Regional Center for Assistive Technology (Centro Regionale Ausili, CRA) in Bologna, Italy. Our purpose was to identify a set of internationally validated instruments and a training cir...

(This article belongs to the Special Issue Outcomes Measurement for Rehabilitation and Assistive Technology: International Perspectives)
  • Review
  • Open Access
1 Citations
5,273 Views
16 Pages

Pellucid Marginal Degeneration: A Comprehensive Review of Pathophysiology, Diagnosis, and Management Strategies

  • Michael Tsatsos,
  • Konstantina Koulotsiou,
  • Ioannis Giachos,
  • Ioannis Tsinopoulos and
  • Nikolaos Ziakas

22 July 2025

Purpose: Pellucid Marginal Degeneration (PMD) is a rare ectatic corneal disorder characterized by inferior peripheral thinning and significant irregular astigmatism. Despite its clinical similarities to keratoconus, PMD presents unique diagnostic and...

(This article belongs to the Section Ophthalmology)
  • Article
  • Open Access
2,592 Views
33 Pages

A WCA-Based Evaluation Approach for Matching Analysis of the Construction Process

  • Hongyu Ye,
  • Hong Zhang,
  • Minjie Sun,
  • Yihan Lv and ,
  • Wensheng Yang,
  • Yinan Gong,
  • Baolin Huang and
  • Meng Cong
  • + 3 authors+ 0 author

8 August 2024

Assessing construction process optimization and efficiency is crucial for the industry, yet quantitative methods for comparison are lacking. We propose the process matching degree (PMD) to quantitatively assess construction processes, enhancing effic...

(This article belongs to the Special Issue Research on BIM—Integrated Construction Operation Simulation)
  • Feature Paper
  • Article
  • Open Access
1 Citations
786 Views
25 Pages

21 January 2026

Planned Missing Designs (PMDs) allow for different sets or patterns of variables to be collected from sample units. While the typical motivation for PMDs is to manage respondent burden, they can also reduce data collection costs and provide flexibili...

  • Article
  • Open Access
85 Views
12 Pages

Transplant-Associated Decline in Pectoral Muscle Density Following Autologous Hematopoietic Stem Cell Transplantation: A Longitudinal CT-Based Study

  • Taner Tan,
  • Zeynep Atceken,
  • Efe Semercioğlu,
  • Erdem Çığ and ,
  • Ahmet Umur Topçu and
  • Sinem Civriz Bozdağ
  • + 1 author+ 0 author

6 November 2026

Background and Objectives: Autologous hematopoietic stem cell transplantation (AHSCT) can lead to skeletal muscle loss owing to the catabolic state and inflammatory burden it induces. Pectoral muscle density (PMD), measured on thoracic CT, is a valua...

(This article belongs to the Special Issue Hematologic Malignancies: Diagnosis, Prognosis and Management)
  • Review
  • Open Access
7 Citations
5,580 Views
12 Pages

30 June 2024

Perimenopausal depression (PMD) is a psychological disorder that occurs in women during perimenopause. In addition to the common clinical symptoms of depression, it often manifests as a perimenopausal complication, and its notable cause is the declin...

(This article belongs to the Section Psychiatry)
  • Review
  • Open Access
63 Citations
18,131 Views
53 Pages

Clinical and Genetic Overview of Paroxysmal Movement Disorders and Episodic Ataxias

  • Giacomo Garone,
  • Alessandro Capuano,
  • Lorena Travaglini,
  • Federica Graziola and ,
  • Fabrizia Stregapede,
  • Ginevra Zanni,
  • Federico Vigevano,
  • Enrico Bertini and
  • Francesco Nicita
  • + 4 authors+ 0 author

Paroxysmal movement disorders (PMDs) are rare neurological diseases typically manifesting with intermittent attacks of abnormal involuntary movements. Two main categories of PMDs are recognized based on the phenomenology: Paroxysmal dyskinesias (PxDs...

(This article belongs to the Special Issue Molecular Mechanisms, Physiopathology and Therapeutic Management of Episodic Ataxia)
  • Article
  • Open Access
12 Citations
4,494 Views
23 Pages

Hypomyelinating Leukodystrophy 7 (HLD7)-Associated Mutation of POLR3A Is Related to Defective Oligodendroglial Cell Differentiation, Which Is Ameliorated by Ibuprofen

  • Sui Sawaguchi,
  • Kenji Tago,
  • Hiroaki Oizumi,
  • Katsuya Ohbuchi and ,
  • Masahiro Yamamoto,
  • Kazushige Mizoguchi,
  • Yuki Miyamoto and
  • Junji Yamauchi
  • + 3 authors+ 0 author

22 December 2021

Hypomyelinating leukodystrophy 7 (HLD7) is an autosomal recessive oligodendroglial cell-related myelin disease, which is associated with some nucleotide mutations of the RNA polymerase 3 subunit a (polr3a) gene. POLR3A is composed of the catalytic co...

  • Article
  • Open Access
3 Citations
5,205 Views
33 Pages

Hypomyelinating Leukodystrophy 8 (HLD8)-Associated Mutation of POLR3B Leads to Defective Oligodendroglial Morphological Differentiation Whose Effect Is Reversed by Ibuprofen

  • Sui Sawaguchi,
  • Rimi Suzuki,
  • Hiroaki Oizumi,
  • Katsuya Ohbuchi and ,
  • Kazushige Mizoguchi,
  • Masahiro Yamamoto,
  • Yuki Miyamoto and
  • Junji Yamauchi
  • + 3 authors+ 0 author

16 February 2022

POLR3B and POLR3A are the major subunits of RNA polymerase III, which synthesizes non-coding RNAs such as tRNAs and rRNAs. Nucleotide mutations of the RNA polymerase 3 subunit b (polr3b) gene are responsible for hypomyelinating leukodystrophy 8 (HLD8...

  • Article
  • Open Access
9 Citations
5,152 Views
22 Pages

Microfabrication Process Development for a Polymer-Based Lab-on-Chip Concept Applied in Attenuated Total Reflection Fourier Transform Infrared Spectroelectrochemistry

  • Noah Atkinson,
  • Tyler A. Morhart,
  • Garth Wells,
  • Grace T. Flaman and ,
  • Eric Petro,
  • Stuart Read,
  • Scott M. Rosendahl,
  • Ian J. Burgess and
  • Sven Achenbach
  • + 4 authors+ 0 author

8 July 2023

Micro electro-mechanical systems (MEMS) combining sensing and microfluidics functionalities, as are common in Lab-on-Chip (LoC) devices, are increasingly based on polymers. Benefits of polymers include tunable material properties, the possibility of...

(This article belongs to the Section Sensor Materials)
  • Review
  • Open Access
13 Citations
5,434 Views
15 Pages

p53, A Victim of the Prion Fashion

  • Olivier Billant,
  • Gaëlle Friocourt,
  • Pierre Roux and
  • Cécile Voisset

13 January 2021

Identified in the late 1970s as an oncogene, a driving force leading to tumor development, p53 turned out to be a key tumor suppressor gene. Now p53 is considered a master gene regulating the transcription of over 3000 target genes and controlling a...

(This article belongs to the Special Issue The Isoforms of the p53 Gene Family and Their Role in Cancer and Aging:Selection Papers from International p53/p63/p73 Isoforms Workshop)
  • Article
  • Open Access
7 Citations
3,231 Views
14 Pages

20 March 2021

There is an urgent need for the development of elastic dielectric materials for flexible organic field effect transistors (OFETs). In this work, detailed analysis of the AC and DC electrical conductivity of a series of flexible poly(dimethylsiloxane)...

(This article belongs to the Special Issue Printed Organic Electronics—Solution Processable Polymers and Interlayers)
  • Review
  • Open Access
30 Citations
8,861 Views
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21 July 2017

Type 2 diabetes (T2D) is characterised by hyperglycaemia resulting from defective insulin secretion, insulin resistance, or both. The impact of over-nutrition and reduced physical activity, evidenced by the exponential rise in obesity and the prevale...

(This article belongs to the Special Issue Effects of Polyphenol-Rich Foods on Human Health)

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