Phidianidines A and B are two novel marine indole alkaloids bearing an uncommon 1,2,4-oxadiazole ring and exhibiting various biological activities. Our previous research showed that the synthesized phidianidine analogs had the potential to inhibit th...
Today, the development of electrified commercial vehicles requires efficient validation methods that enable early system testing while maintaining consistency between development and testing models. Hardware-in-the-Loop (HiL) testing provides a suita...
This review focuses upon the use of nitroso Diels–Alder reactions as a structural complexity generating reaction that has been so far a quite scarcely treated topic, despite its potential. In particular, the use of N-acyl-1,2-dihydropyridines a...
Pterolobirin H (3), a cassane diterpene isolated from the roots of Pterolobium macropterum, exhibits important anti-inflammatory and anticancer properties. However, its relatively complex tetracyclic structure makes it difficult to obtain by chemical...
This paper presents a planar four-bar approximate motion synthesis technique that uses only pole locations. Synthesis for rigid-body guidance determines the linkage dimensions that guide a body in a desired manner. The desired motion is specified wit...
Farmland ecosystems provide multiple ecosystem functions and ecosystem services and underpin regional ecological security and integrity. Despite substantial progress in FESFS research, integrated syntheses linking ecological mechanisms, multiple ecos...
Planar multi-loop mechanisms often generate a large number of non-isomorphic candidate topological graphs during automatic synthesis, making it difficult to efficiently identify configurations that satisfy engineering-oriented functional requirements...
N6-methyladenosine (m6A) methylation functions as a vital post-transcriptional and epigenetic modification in higher plants regulated by α-ketoglutarate-dependent dioxygenases (ALKBH). However, the role of ALKBH genes in oriental melon (Cucumis...
Reducing the specific energy consumption of reverse osmosis (RO) processes motivates the development of new membrane materials that have enhanced water permeability while maintaining low salt permeability (high rejection). Nanocomposite membranes hav...
Additive manufacturing of lightweight or functional structures by selective laser beam (SLM) or electron beam melting (EBM) is widespread, especially in the field of medical applications. SLM and EBM processes were applied to prepare Ti6Al4V test spe...
The increasing demand for sustainable and environmentally synthesis routes has driven significant interest in biogenic precursors for nanomaterial fabrication. Among these, egg-derived materials—including eggshell, eggshell membrane (ESM), egg...
3d transition metals-catalyzed C–H bond functionalizations represent nowadays an important tool in organic synthesis, appearing as the most promising alternative to cross-coupling reactions. Among 3d transition metals, iron found widespread app...
MXenes, a rapidly expanding family of two-dimensional transition-metal carbides and nitrides, are increasingly viewed as strong candidates for defense-oriented multifunctional systems because they combine metallic conductivity, surface tunability, me...
The exploitation of metallacarboranes’ potential in various fields of research and practical applications requires the availability of convenient and versatile methods for their functionalization with various functional moieties and/or linkers...
Background: Proximal–distal orientation of nerve autografts (graft polarity) is an important consideration in peripheral nerve repair, but the literature is inconsistent on whether reversing graft polarity improves regeneration. With these disp...
Although various synthetic methodologies including organic synthesis, polymer chemistry, and materials science are the main contributors to the production of functional materials, the importance of regulation of nanoscale structures for better perfor...
After synthesis of transmembrane proteins (TMPs), they are transferred and inserted into plasma membranes to play biological functions. Crucially, orientation of TMPs in membranes determines whether they have biological activities. In cellular enviro...
A layer-by-layer method has been developed for the synthesis of metal-organic frameworks (MOFs) and their deposition on functionalized organic surfaces. The approach is based on the sequential immersion of functionalized organic surfaces into solutio...
The design, construction, and operation of devices and machines at the molecular scale using the bottom-up approach captivates a lot of interest in nanoscience. Particularly intriguing are interlocked molecular architectures, which are ideal candidat...
With the widespread application and functional complexity of deep neural networks (DNNs), the demand for training samples is increasing. This elevated requirement also extends to DNN-based SAR object detection. Most public SAR object detection datase...
(1) Background: The continuous growth of rehabilitation literature makes evidence synthesis increasingly challenging. Lexical network analysis may provide quantitative information on the organization of scientific knowledge. This study aimed to chara...
A functionally graded composite NiAl-AlMg6 was prepared using the pressure of gaseous reaction products (impurity gases) produced during the synthesis of reactive powders in a sealed reactor. It has been shown that this method can be used to prepare...
Trends in the dynamically developing application of biocatalysis for the synthesis and modification of polymers over the past 5 years are considered, with an emphasis on the production of biodegradable, biocompatible and functional polymeric material...
Functionally substituted 1,2,5-oxadiazole 2-oxides (furoxans) are important pharmaceutical scaffolds used for the preparation of various pharmacologically active substances. Furoxans bearing hydrazone functionality are considered as promising drug ca...
Magnetic iron oxide nanoparticles (MIONPs) represent a versatile magnetic nanoparticle (NP) system with considerable, yet underexplored, potential in diverse applications, particularly in emerging biomedical fields such as magnetic resonance imaging,...
The Diels–Alder cycloaddition between bisdienes and bisdienophile incorporating the 7-oxa-bicyclo[2.2.1]heptane unit are well known to show high diastereoselectivity that can be exploited for the synthesis of molecular belts. The related bisdiene 5,6...
Global Navigation Satellite Systems (GNSS) underpin maritime Positioning, Navigation, and Timing (PNT), supporting bridge functions such as the Automatic Identification System (AIS), the Electronic Chart Display and Information System (ECDIS), radar...
Zinc oxide nanoparticles (ZnO-NPs) have gained increasing attention across food, biomedical, environmental, and many industrial fields due to their antimicrobial properties, chemical stability, and favorable physicochemical characteristics. In parall...
Public participation is integral to contemporary planning and decision-making, yet knowledge of methods beyond formally prescribed procedures remains fragmented across the academic and practice-oriented literature. Terminological inconsistencies and...
The main purpose of the paper is to present technology mapping of FSM (finite state machine) oriented to LUT (look-up table)-based FPGA (field-programmable gate array). The combinational part of an automaton, which consists of a transition block and...
We report the synthesis and properties of a new thiazolothiazole (TzTz)-based semiconducting polymer incorporating the dithienothienothiophenebisimide (TBI) unit, named PTzTBI. PTzTBI showed relatively deep HOMO and LUMO energy levels of −5.48...
Although the synthesis of molybdenum disulfide (MoS2) on sapphire has made a lot of progress, how the substrate surface affects the growth still needs to be further studied. Herein, the impact of the sapphire step height on the growth of monolayer Mo...
The Advanced Encryption Standard (AES-128) is widely used in high-speed secure communication systems, requiring efficient ASIC-oriented hardware implementations. To ensure that the implementation achieves full functional correctness and coverage, thi...
23 August 2021
There is an increasing call for recovery-oriented services but few reviews have been undertaken regarding such interventions. This review aims to synthesize evidence on recovery services to improve the lives of adults living with severe mental illnes...
Tuta absoluta (Meyrick) is an important invasive pest that seriously affects the yield and quality of tomatoes. In this study, based on the previously obtained transcriptome data, a total of 25,123 SSR loci and 332,537 SNP loci were identified. The i...
Drawing on a systematic review of both international and Chinese-language scholarship on counter-urbanization in China, this article proposes a comprehensive typology of counter-urbanization migrations—consisting of eight types of new migrants&...
The recent development in polymer science has gone beyond the traditional linear and randomly functionalizable macromolecules to the architected polymer systems, which integrate modular synthesis and dynamic responsiveness. Although the literature re...
Enzyme catalysis is a very active research area in organic chemistry, because biocatalysts are compatible with and can be adjusted to many reaction conditions, as well as substrates. Their integration in multicomponent reactions (MCRs) allows for sim...
A general Rh-catalyzed addition reaction of nitrogen containing heterocycles to internal allenes is reported. Starting from racemic internal allenes a dynamic kinetic resolution (DKR) provides N-allylated triazoles and tetrazoles. Simultaneous contro...
N-containing heteroaromatics are important substructures found in numerous natural or synthetic alkaloids. The diversity of the structures encountered, as well as their biological and pharmaceutical relevance, have motivated research aimed at the dev...
Osteocalcin (Ocn), which is specifically produced by osteoblasts, and is the most abundant non-collagenous protein in bone, was demonstrated to inhibit bone formation and function as a hormone, which regulates glucose metabolism in the pancreas, test...
Magnetic graphene composites have emerged as a frontier material platform, offering designable properties and multifunctional integration across environmental, biomedical, electromagnetic, and energy applications. Despite extensive research, a cohere...
Complex psychosis is a clinically relevant rehabilitation construct rather than a formal diagnostic category and refers to psychotic illness associated with treatment-resistant symptoms, functional impairment, and additional cognitive, psychiatric, n...
Multicomponent processes are beneficial tools for the synthesis of heterocycles. As densely substituted bifunctional electrophiles, ynones are essential intermediates by applying cyclocondensations or cycloadditions in numerous heterocycle syntheses....
MXenes have emerged as a rapidly expanding family of two-dimensional transition-metal carbides, nitrides, and carbonitrides, characterized by exceptional compositional diversity, tunable surface chemistry, metallic conductivity, hydrophilicity, mecha...
Palladium-catalysed reactions have had a large impact on synthetic organic chemistry and have found many applications in target-oriented synthesis. Their widespread use in organic synthesis is due to the mild conditions associated with the reactions...
In this work, we report a green synthesis of zinc oxide (ZnO) nanoparticles using aqueous and ethanolic extracts of Tradescantia spathacea (purple maguey) as bioreducing and stabilizing agents, which are plant extracts not previously employed for met...
Amblyopia is increasingly conceptualized as a neurodevelopmental visual disorder that often arises from discordant binocular visual experience during early life and is associated with abnormal binocular interactions, interocular suppression, orientat...
Background/Objectives: Oral tongue squamous cell carcinoma (OTSCC) remains clinically challenging because conventional clinicopathological markers do not fully explain variability in recurrence and survival. This systematic review and functional meta...
Polylactic acid (PLA) is chosen as a material-extrusion additive-manufacturing (AM) feedstock due to its bio-origin, degradability, processability, and design for geometries. The mechanical, thermal, toughness, and functional limitations of neat PLA...
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