New Insights in Diversity Oriented Synthesis

Dear Colleagues,

Diversity oriented synthesis (DOS) is a well established and powerful strategy for the synthesis of highly diversified collections of compounds. DOS requires the availability of efficient synthetic pathways, which should be environmentally benign, short, selective, and atom economical. Stereocontrol can in some instances be an important challenge too. This means that in the future the main question will no longer be "if" but "how efficiently" a molecule (or a collection of similar molecules) can be synthesized. This Special Issue is focussed on two main topics, accordingly with a new philosophy within organic synthesis based on the sustainability: a) the valorization of the starting materials, which should be easily accessible possibly from "bio-based" renewable materials (for example biomass or waste), with the aim to replace in the next future the oil-based chemistry; b) the efficiency of the synthetic methodologies planned to transform the starting materials into the new molecules. In particular catalytic methodologies, including biocatalysis, organocatalysis, photocatalysis, transition metal-based domino or one-pot reactions, can offer an excellent contribute to this goal. Moreover, Multicomponent reactions and green synthetic pathways can support as well the sustainability of the synthtic metodologies, allowing at the same time a diversity oriented approach.

Communications, full papers and short reviews on this topic are really appreciated and welcome.

Prof. Renata Riva
Guest Editor

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