Low-cost gas sensor arrays are attractive for mixed-gas monitoring, but deployment-oriented modeling remains challenging because mixed-gas responses are nonlinear, cross-sensitive, and strongly dependent on sensor dynamic states. Existing electronic-...
Quantifying metabolites from various biological samples is necessary for the clinical and biomedical translation of metabolomics research. One of the ongoing challenges in biomedical metabolomics studies is the large-scale quantification of targeted...
Zinc and copper are essential cations involved in numerous biological processes, and variations in their concentrations can cause diseases such as neurodegenerative diseases, diabetes and cancers. Hence, detection and quantification of these cations...
Distributed photovoltaic (PV) systems play an important role in supporting low-carbon and sustainable distribution network development; however, their high-penetration integration can cause nodal overvoltage, as midday PV generation often exceeds loc...
In wind-assisted orchard spraying operations, the dynamic response of leaves—manifested through changes in their posture—critically influences droplet deposition on both sides of the leaf surface and the penetration depth into the canopy....
The lack of access to drinking water is a problem affecting many regions worldwide. In Santa Fe, Argentina, the population uses groundwater as a source of drinking water. Unfortunately, it has high concentrations of As(V), which makes it unsuitable f...
The development of the electrification of aircraft has prompted aviation hydraulic systems to shift from traditional centralized valve actuators (CVAs) to electro-hydrostatic actuators (EHAs). In this paper, aiming at the demand for a quantitative co...
In this review, we explore the complexities of objectively assessing the response to immunotherapy in mycosis fungoides (MF), a prevalent form of cutaneous T-cell lymphoma. The core challenge lies in distinguishing between reactive and malignant lymp...
Background: Cyclosporin A (CyA) is widely investigated for ophthalmic drug-delivery systems, including hydrogel contact lenses, where reliable quantification is essential for evaluating drug loading, release, and formulation performance. However, the...
In 2019, a novel coronavirus emerged in Wuhan in the province of Hubei, China. The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) quickly spread across the globe, causing the neoteric COVID-19 pandemic. SARS-CoV-2 is commonly transmitte...
Non-target screening utilizing liquid chromatography–high-resolution mass spectrometry is increasingly employed for the environmental monitoring of contaminants; however, obtaining quantitative results of detected suspected compounds is challen...
Combination drug treatment plays a central role in addressing complex diseases by enhancing the therapeutic benefit while mitigating adverse effects. However, determining optimal dose levels remains challenging due to additive drug effects, competing...
Pavement cracks pose significant challenges to the driving stability and operational safety of automated guided vehicles (AGV) in industrial and logistics environments. The complex geometry of cracks and their nonlinear coupling with vehicle dynamics...
Piezoelectric structures are widely used in engineering designs including sensors, actuators, and energy-harvesting devices. In this paper, we present the development of a three-dimensional finite element model for simulations of piezoelectric actuat...
Increasing the penetration of variable energy resources (VER) can reduce the inertia and frequency response performance of power systems supported by replacement synchronous power generation. Therefore, it is necessary to manage the VER penetration l...
Research relating to dielectrophoresis (DEP) has been progressing rapidly through time as it is a strong and controllable technique for manipulation, separation, preconcentration, and partitioning of protein. Extensive studies have been carried out o...
7 November 2024
Because soundscapes affect human health and comfort, methodologies for evaluating them through physiological responses have attracted considerable attention. In this study, we proposed a novel method for evaluating visual attention by using eye-track...
High-energy radiation is known to potentially impact the optical performance of silicon-based sensors adversely. Nevertheless, a proper characterization and quantification of possible spectral response degradation effects due to UV stress is technica...
We examined the within-player correlation between external training load (ETL) and perceptual responses to training in a professional male football team (n = 13 outfield players) over an eight-week competitive period. ETL was collected using 10-Hz GP...
30 September 2019
In this review, we critically evaluated the evidence of exposure–response relationships between occupational workload and the risk of hip osteoarthritis. The existing evidence was evaluated in order for us to extrapolate possible doubling risk...
The macronutrient potassium is essential to plant growth, development and stress response. Alligator weed (Alternanthera philoxeroides) has a high tolerance to potassium deficiency (LK) stress. The stem is the primary organ responsible for transporti...
Chlorophyll a concentration (Chla) is a well-proven proxy of biocrust development, photosynthetic organisms’ status, and recovery monitoring after environmental disturbances. However, laboratory methods for the analysis of chlorophyll require d...
The evaluation of seismic performance of existing masonry buildings is a critical issue in assessing the seismic vulnerability of the built environment. With this aim, non-linear static analysis is commonly used, but results are influenced significan...
In this paper, we give an overview of the issues one must consider when designing methods for vibration based health monitoring systems for perforated thin shells especially in relation to frequency response analysis. In particular, we allow either t...
Nanotechnology and polymer engineering are navigating toward new developments to control and overcome complex problems. In the last few decades, polymer engineering has received researchers’ attention and similarly, polymeric network-engineered...
The response forecasting of in-service complex electronic systems remains a challenge due to its uncertainty. An AI-based adaptive surrogate modeling method, including offline and online learning procedures, is proposed in this research for different...
Accurate finite element models are essential for structural condition assessment, yet nominal material properties and idealized boundary conditions can produce systematic discrepancies between numerical and measured dynamics. This study proposes a ph...
There have been many attempts in pharmaceutical industries and academia to improve the pharmacokinetic characteristics of anti-tumor small-molecule drugs by conjugating them with large molecules, such as monoclonal antibodies, called ADCs. In this co...
Given the randomness inherent in fluid dynamics problems and limitations in human cognition, Computational Fluid Dynamics (CFD) modeling and simulation are afflicted with non-negligible uncertainties, casting doubts on the credibility of CFD. Scienti...
To establish a high-fidelity model of engineering structures, this paper introduces an improved Bayesian model updating method for stochastic dynamic models based on frequency response functions (FRFs). A novel validation metric is proposed first wit...
Industrial potato processing generates substantial rejected-tuber streams that are rarely valorized. This study optimized wet-process starch extraction from rejected Solanum tuberosum L. (Pastusa variety) sourced from a Colombian snack processor (Com...
The roller–raceway contact response is a key factor affecting stress concentration, fatigue initiation, and raceway spalling in spherical roller thrust bearings. Uncertainty analysis of this response is therefore important for revealing how pra...
Cavitation damage poses a serious threat to the reliability of morning-glory spillways. This study aims to develop a reliability framework for predicting cavitation damage probability under uncertain operational conditions for the Haraz Dam spillway....
Centralized hot water systems in university dormitories can provide significant energy flexibility through demand response (DR). Thus far, however, existing studies have mainly focused on system-level optimization and have failed to provide a quantit...
Sustainable machining of composite materials requires optimizing conflicting responses influenced by limited experimental datasets, trade-offs, nonlinear process variables, and response variability. This study proposes a hybrid framework (Gaussian Pr...
Chronic thromboembolic pulmonary hypertension (CTEPH) is confirmed by visual analysis of single-photon emission computer tomography (SPECT) ventilation and perfusion (V/Q) images. Defects in the perfusion image discordant with the ventilation image i...
In cancer pharmacology, a drug candidate’s therapeutic potential is typically expressed as its ability to suppress cell growth. Different methods in assessing the cell phenotype and calculating the drug effect have been established. However, in...
Model validation for complex simulation models with multivariate functional responses poses significant challenges, as it involves the dual coupling of physical correlations among variables and field correlations in time-series data. A novel Autoenco...
The analytical solution for the displacements of an anisotropic piezoelectric material in the uniform electric field is presented for practical use in the “global excitation mode” of piezoresponse force microscopy. The solution is given in the Wolfra...
Immune-checkpoint inhibitors (ICIs) have been proven to have great efficacy in non-small cell lung cancer (NSCLC) as single agents or in combination therapy, being capable to induce deep and durable remission. However, severe adverse events may occur...
Millettia pulchra is traditionally used for treating diseases, including joint pain, fever, anemia, and allergies. It is also a potential resource of natural flavonoid derivatives, which represents major constituents of this plant. This study aimed t...
Structural health monitoring is effective if it allows us to identify the condition state of a structure with an appropriate level of confidence. The estimation of the uncertainty of the condition state is relatively straightforward a posteriori, i.e...
Frequency response analysis under uncertainty is computationally expensive. Low-rank approximation techniques can significantly reduce the solution times. Thin perforated cylinders, as with all shells, have specific features affecting the approximati...
Cloud defenders increasingly want to anticipate an attacker’s next move, not merely detect the last one. We study attack-path forecasting in multi-cloud environments: given the partial trace of an in-progress campaign, predict the next ATT&...
Background: Commercial cytokine assays may not span the concentrations encountered in perioperative serum. We examined the extent to which reconstructed enzyme-linked immunosorbent assay data from a total hip arthroplasty cohort could support tempora...
Acrylonitrile butadiene styrene (ABS) offers good mechanical properties and is effective in use to make polymeric structures for industrial applications. It is one of the most common raw material used for printing structures with fused deposition mod...
Incentive-based demand response (DR) programs rely on accurate and trustworthy quantification of customer performance to ensure fair compensation and market efficiency. Estimating the customer baseline load is an important part of this process. It sh...
Bridges are critical infrastructures that support our economic activities and daily lives. Aging bridges have been a major issue for decades, prompting researchers to improve resilience and performance through structural health monitoring. While most...
The release of 1,4-dioxane probably contributes to the deterioration of marine habitats, animal health, and human liver and kidneys. The formulation of 1,4-dioxane in glycols, which has been applied for dehumidifying agents in refineries, may need to...
Background/Objectives: Tumor-infiltrating lymphocytes (TILs) are recognized predictors of response to neoadjuvant chemotherapy (NACT) and prognosis in breast cancer, particularly in triple-negative (TN) and HER2-positive subtypes. However, the additi...
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