AI

Background and Objectives: Post-hepatectomy liver failure (PHLF) remains the leading cause of mortality following hepatic resection, with reported incidence rates ranging from 1.2% to 32%. Traditional scoring systems such as the Child–Pugh score, Model for End-Stage Liver Disease (MELD), and Albumin–Bilirubin (ALBI) grade have demonstrated limited predictive accuracy for PHLF. Machine learning (ML) algorithms have emerged as promising tools capable of integrating complex, multidimensional clinical data to improve predictive performance. This systematic review aims to evaluate the current evidence on ML-based prediction models for PHLF, assessing their predictive accuracy, methodological quality, clinical applicability, and the key variables utilized across models. Methods: A systematic literature search was conducted across PubMed, Embase, Web of Science, and the Cochrane Library from inception to January 2026. Studies that developed or validated ML models for predicting PHLF after hepatic resection were included. The Prediction Model Risk of Bias Assessment Tool (PROBAST) was used to evaluate the risk of bias. Data on model performance, algorithms employed, sample sizes, predictor variables, and validation strategies were extracted. The review was conducted in accordance with the PRISMA 2020 guidelines and registered in PROSPERO. Results: Twelve PubMed-verified studies involving 6913 patients were retained in the final analysis. Publication years ranged from 2020 to 2025, with five studies published in 2025. Gradient boosting approaches (LightGBM/XGBoost or phase-specific boosting models) were the most frequent best-performing architectures, while ANN/deep learning, radiomics-integrated, and ensemble approaches also showed clinically relevant discrimination. Best reported non-training AUCs ranged from 0.7927 to 0.981 (median, 0.873). The strongest generalization signals came from studies with temporal, external, or prospective validation structures. Common predictor domains included bilirubin-based liver function measures, coagulation variables, platelet count, volumetry or extent of resection, imaging-derived radiomics features, and perioperative dynamic data. Conclusions: Machine learning models remain promising for PHLF prediction, but the evidence base is smaller and more heterogeneous than the original draft suggested. Performance is highest in studies that combine clinical liver-reserve markers with imaging or perioperative temporal data; however, widespread clinical adoption is still limited by retrospective design predominance, inconsistent outcome definitions, and incomplete external validation. Full article

In recent years, with the advancement of production technology in the manufacturing industry, the scheduling problems that rely on modeling in real-world scenarios have gradually evolved into complex process flows. Aiming at the limited problem modeling capabilities of existing scheduling problems, this study proposes Multi-Stage Flexible Job Shop Scheduling Problem (MS-FJSP). MS-FJSP alters the fixed operation processing sequence of jobs in conventional scheduling problems and introduces staged processing to incorporate flexible constraints on operation selection. Furthermore, MS-FJSP modifies the constraint of unique machine compatibility, enabling arbitrary adjustments to machine combinations according to processing requirements. To address the complex flexibility and large-scale solution space of MS-FJSP, we propose a particle swarm optimization algorithm based on double neighborhood tabu search (TS-PSO). Specifically, the PSO algorithm determines a superior neighborhood structure for this problem, while the TS algorithm improves and optimizes the solution quality within the neighborhood of this solution structure. We verify the algorithm’s performance using a dataset consisting of 12,000 MS-FJSP instances and an MS-FJSP instance modeled from a real-world scheduling scenario. Experimental results demonstrate that TS-PSO can achieve excellent solution quality within a reasonable time, and MS-FJSP possesses efficient modeling capability for real-world scheduling scenarios. Full article

Optical coherence tomography plays a critical role in diagnosing retinal diseases, yet automated deep learning classification is hindered by severe class imbalance in which rare pathologies are underrepresented and frequently misclassified, a limitation rarely exposed by the aggregate metrics reported in most prior work. We investigate a targeted intermediate-supervision framework, in which a secondary classifier head is attached to mid-level backbone features and jointly optimized with the primary classifier using inverse-frequency weighted loss. Unlike conventional deep supervision, which is primarily aimed at optimizing stability, the proposed formulation is used here to improve minority-class representation under severe OCT class imbalance. The method is evaluated on ResNet-18, ResNet-50, EfficientNet-B0, and ViT-B/16 using a four-class OCT dataset, with full per-class metrics reported across a systematic ablation of the auxiliary weight λ. EfficientNet-B0 achieved the best performance at λ = 0.3, attaining 97.78% accuracy, an AUROC of 0.995, and a Drusen F1-score of 93.51%, a gain of 2.64 percentage points over the unweighted baseline. Vision Transformers showed greater sensitivity to background padding artifacts than convolutional models. Grad-CAM and Attention Rollout analyses confirm that auxiliary supervision improves the localization of clinically relevant retinal structures, supporting its potential for interpretable, class-balanced automated OCT diagnosis. Full article

Machine learning has a wide range of applications, including classification, which categorizes elements based on their characteristics. This paper addresses the challenge of optimizing attribute weighting while assessing two crossover operators on differential evolution optimization and increasing the performance of the k-nearest neighbors classification algorithm (KNN). We use a differential evolution optimization method and assess the performance of both the differential evolution and the harmony crossover operators. Finally, the optimization method uses the accuracy of a KNN classification algorithm as a fitness function. The results show that the proposed method significantly enhances the KNN performance while proposing an alternative for other classification models such as neural networks and Random Forest. Full article

This paper presents an innovative methodology detecting out-of-distribution individuals based on a multimodal contrastive learning approach. The system combines voice and facial image data by projecting them into a shared representation in the embedding space, enable accurate identification of previously unseen individuals. This approach overcomes the limitations of traditional methods by providing more robust and consistent detection in dynamic scenarios, using advanced neural networks and optimized contrastive losses. Specifically, the main contribution of this work is the introduction of a multimodal contrastive framework that performs cross-modal consistency verification between facial and vocal representations, enabling reliable detection of out-of-distribution individuals without the need for identity gallery retrieval. Experimental results on multiple datasets highlight the effectiveness of the system, with accuracy above 90% in detecting in-distribution samples in all evaluated cases. Regarding the identification of out-of-distribution cases, the system maintains outstanding performance, achieving values close to 90% on average, with some datasets exceeding 95%. These results underscore its ability to recognize both known identities and handle unknown data, even under challenging conditions. This approach represents a significant advancement in the multimodal recognition of individuals, with potential applications in critical areas such as security, surveillance, and human–computer interaction. Full article

Technical documents differ from general text corpora in ways that complicate retrieval-augmented generation (RAG). Evidence for a single answer is often distributed across numbered clauses, tables, figures, captions, and ordered procedures rather than expressed in one passage. Standard RAG pipelines typically flatten these elements into independent chunks. This can break the document relations needed for exact evidence tracing. We introduce TechDocRAG, a relation-preserving framework for technical document question answering. The framework represents each document as a heterogeneous element graph and aligns three retrieval views for each element: technical identifiers, semantic summaries, and raw evidence. At query time, retrieval proceeds from identifier-aware recall to summary-level reranking and raw evidence bundling. We evaluate TechDocRAG on four benchmarks with more than 7500 evaluated question–answer pairs covering product manuals, engineering documents, and long multimodal PDFs. Across the suite, TechDocRAG improves the mean end-to-end score by 20.3 points over the strongest flat baseline and by 9.3 points over the strongest non-flat baseline. On the evidence-annotated subset, the strict raw evidence hit rate increases from 0.510 to 0.942. Resource profiling shows query time latency comparable to standard hybrid retrieval. Robustness tests show gradual degradation under relation loss, but clear sensitivity to severe identifier corruption. Overall, the results indicate that reliable RAG for technical documents depends less on retrieving more passages than on preserving the relations that make evidence interpretable. Full article

Artificial intelligence techniques have made notable progress in supporting learning processes, with increasing adoption across educational contexts. However, despite the increasing work on AI-assisted techniques, explicit and implicit learning mechanisms in AI educational assistants have not been systematically categorised. The study of how these techniques aid in and are implemented for learning remains underexplored. Therefore, a more systematic categorisation of how these techniques support learning through user interaction is needed. This paper presents a systematic review of 38 studies published between 2000 and 2024, spanning domains including programming education, cognitive skills, language learning, and the AI field. This review was conducted and reported in accordance with the PRISMA 2020 guidelines. In this review, we propose a taxonomy of explicit and implicit learning features. We analyse implementation aspects (e.g., knowledge representation, algorithms, and interaction modalities) and synthesise how prior work evaluates learning support capabilities. The findings show that (i) 79% of reviewed studies support explicit and 21% supported implicit learning through interaction; (ii) written interaction dominates (45%), followed by visualisation (34%), while voice-based interaction remains underrepresented (9%); (iii) some implementations lack details (e.g., knowledge bases and validation methods); and (iv) evaluation practices remain uneven, with most studies relying on experiment evaluation, highlighting the need for robust evaluation practices. Full article

Galaxy morphology combines measurable structural properties with subjective visual interpretation, limiting strictly hard-label classifications. This study proposes a framework designed to compare physically derived and human-based galaxy classifications while explicitly accounting for uncertainty and interpretability. Using photometric and structural features from the Sloan Digital Sky Survey (SDSS), physical groupings are obtained through Fuzzy C-Means clustering, enabling gradual transitions via soft memberships. Human clusters are constructed from Galaxy Zoo 2 debiased vote fractions, capturing aggregated perceptual judgments. Supervised models are trained to predict both physical and human cluster assignments from the same set of physical variables, providing a quantitative assessment of structural coherence and perceptual–physical alignment. SHAP-based explainability identifies the relative influence of color and concentration parameters in each scheme. Results show that physical clustering is driven by structural concentration and bulge dominance, while human classification exhibits smoother decision boundaries and greater sensitivity to photometric appearance. Discrepancies concentrate in transitional and orientation-sensitive systems. An interactive visualization layer supports traceable qualitative inspection. The framework provides a reproducible methodology for analyzing classification consistency, uncertainty, and human–model alignment. Full article

Higher technical and professional education is increasingly discussed in relation to workforce readiness, innovation, and societal inclusion. In Italy, the PNRR-funded Rome Technopole operates as a multi-institutional ecosystem in which universities, research organizations, industry, and public bodies interact through a Hub & Spoke model to support training and innovation activities. Among its components, Spoke 4 addresses professional higher technical education through the co-development of modular learning initiatives involving multiple stakeholders. This commentary examines the role and activities of the Italian National Institute of Health (ISS) within this context, with particular reference to the development of two pilot modules: one on Artificial Intelligence and Algorethics, and one on Accessibility and Assistive Technologies, including applications supported by AI. The paper combines a conceptual discussion of the approach with selected empirical insights derived from pilot implementation, including stakeholder engagement processes, structured evaluations, and thematic prioritization exercises. The findings suggest the perceived relevance of multi-stakeholder co-design, the use of flexible and modular learning formats, and the integration of technical and ethical dimensions in higher technical education. At the same time, they point to challenges related to coordination, scalability, and alignment across institutional actors. Rather than proposing a definitive model, the Spoke 4 experience is discussed as a context-specific case that may offer insights contributing to ongoing debates on the design and implementation of higher technical education in complex, multi-institutional settings. Full article

This study aims to develop and experimentally evaluate an artificial neural network-based temperature control strategy for hot-air carrot drying within an IoT-enabled cyber-physical system. The experimental setup employs an Arduino Mega 2560 equipped with AM2302 (air temperature sensor), MLX90614 (infrared surface temperature sensor), and SHT35 (relative humidity sensor), an HX711 load cell, and a WS68 anemometer, with cloud communication provided by an ESP8266 module for remote monitoring via Wi-Fi. The neural controller, implemented using the Arduino Neurona library, regulates the dryer temperature in real time, enabling drying kinetics analysis under ANN-based thermal control to investigate its capability to maintain thermal stability. Three initial loads (2, 4, and 6 kg) were analyzed to determine the thermal efficiency. In the dehydration experiments, the 2 kg load reached a final moisture content of 10% in 4.4 h, consuming 1390 kJ with a thermal efficiency of 83%. The 4 kg load exhibited the best time–energy balance (6.6 h, 1850.0 kJ, 88%), while the 6 kg load achieved the highest efficiency (8.1 h, 2250.0 kJ, 91%). These results demonstrate the effectiveness of neural-network-based control implemented on low-cost microcontrollers to enhance thermal efficiency in food dehydration processes. Full article

Semantic segmentation of high-resolution remote-sensing images is critical for urban planning, land-cover mapping, and ecological monitoring. However, existing methods face limitations in handling complex land-cover types, multi-scale objects, and modeling long-range dependencies. To address these challenges, we propose RFA2Net, an enhanced semantic segmentation model based on the DeepLabv3+ framework. The key innovations include the integration of the RFCSA-Conv module into the ResNet101 backbone to enhance feature representation and long-range dependency modeling, the design of the RFA-DASPP structure built upon the Dense ASPP framework with the novel RFCA-DConv dilated convolution module to reduce information loss during multi-scale feature fusion and enhance the model’s ability to perceive long-range directional structures, and the introduction of a Dual-Branch Fusion Network to improve segmentation accuracy for small-scale objects. Experimental results on the ISPRS Potsdam and LoveDA datasets demonstrate that RFA2Net outperforms several CNN and Transformer-based models, achieving 78.94% and 59.46% mean intersection over union (mIoU) on the ISPRS Potsdam and LoveDA datasets, respectively, with improvements of 3.19% and 3.08% over the original DeepLabv3+. Ablation studies and comparative experiments further confirm the model’s effectiveness, robustness, and practical applicability in high-resolution remote-sensing image segmentation, with particular relevance to environmental monitoring and sustainable energy applications. Full article

The integration of artificial intelligence (AI) into the diagnosis and prognosis of heart diseases is transforming cardiovascular and cardiac healthcare, improving predictive accuracy, and personalizing treatment plans. This review presents a novel contribution by providing a comprehensive overview of both diagnosis and prognosis in heart diseases through AI, covering ML and DL models. Following the PRISMA guidelines, a total of 84 recent research articles sourced from significant journals are reported. A bibliometric analysis using the VOSviewer tool was performed to map the impact of AI, enabling a detailed examination of academic connections and contributions. The findings reveal that DL models were employed 63% for diagnosis tasks, while ML models were utilized in 37% of the studies. Key recommendations include the incorporation of essential model evaluation metrics, as clinical validation indicators, integrating explainable artificial intelligence (XAI) to improve the transparency and interpretability of models, and adopting standardized frameworks to enable smooth clinical integration. This review highlights the potential of AI to improve cardiac and cardiovascular diagnosis and prognosis, providing an overview of its strengths, limitations, challenges and the possible application as AI-driven tools in patient monitoring and to support specialists in the decision-making process. Full article

In the past 20 years, Artificial Intelligence (AI) has made several advancements. Because of AI’s ability to process large datasets better than humans, it is thought to have a promising future in many fields. Despite their advantages, AI and specifically Machine Learning (ML) algorithms can have emergent behavior, which makes their adoption into safety-critical systems a challenge. Through an examination of the capabilities of AI systems at NASA, we see what AI is currently being used for and which algorithms are promising for future work. We also identify limitations in the potential impact of AI systems, noting that the majority of the reviewed papers focused on limitations in adopting AI systems rather than limitations in the technical abilities of AI systems. This review article provides insight into AI and ML algorithms, aviation, space and other AI-based platforms for automation. Full article

Building reliable vehicle detection models for intelligent transportation systems calls for large, well-annotated datasets—yet gathering and labelling real traffic data remains both costly and labour-intensive. This paper introduces Traffic Synth, an automated pipeline that generates synthetic training datasets by altering real traffic camera images rather than constructing entirely artificial scenes. The system begins by detecting vehicles through instance segmentation and removing them from the frame. It then places new vehicles directly into the cleared regions using diffusion-based inpainting, all while retaining the original road layout, lighting, and camera perspective. Doing so preserves the realistic scene context while broadening the visual variety of vehicles in the dataset. To ensure that the resulting traffic looks physically plausible, we incorporate a lane-aware prompting mechanism that matches each vehicle’s orientation to the direction of travel as seen from the camera. The system further draws on a weighted vehicle brand database that mirrors the makes and colours commonly found on European roads to better match actual deployment conditions. Class-specific mask processing—involving anisotropic scaling and relative dilation—rounds out the pipeline by improving generation quality across different vehicle size categories. The final output is a set of images with automatically generated annotations in a standard object detection format. Full article

Large Language Models (LLMs) are increasingly deployed across professional and societal domains, introducing security, privacy, and governance challenges beyond traditional software vulnerabilities. Despite extensive research on individual risk categories, a unified lifecycle-oriented perspective connecting architectural properties, adversarial threats, and governance implications remains limited. This review examines security and privacy risks associated with LLMs through a lifecycle framework covering data acquisition, model training, alignment procedures, deployment, and post-deployment interaction. The study synthesizes prior research to construct a taxonomy of threats including prompt injection, jailbreaking, adversarial manipulation, training-stage attacks, privacy leakage, and socio-technical misuse. Ethical issues such as hallucination, bias amplification, and malicious use are analyzed alongside governance and regulatory frameworks. Results indicate that vulnerabilities in LLM systems arise primarily from probabilistic generation mechanisms, large-scale data ingestion, and complex deployment ecosystems rather than isolated implementation defects. Classical software vulnerability models therefore provide only partial coverage of risks associated with generative AI systems. The review is grounded in the concept of the alignment gap to explain how discrepancies between training objectives and real-world interaction contribute to persistent vulnerabilities. The findings highlight the need for lifecycle-oriented defense-in-depth strategies combining technical safeguards, privacy-preserving training, runtime monitoring, and governance mechanisms to support responsible deployment of LLM-based systems. Full article

Multilingual learning is key in natural language processing, but is challenged by the transfer–interference trade-off, where positive transfer benefits certain languages, while negative interference affects others. Prior methods, including linguistic-based and embedding-based language clustering, have attempted to address this; yet, they remain constrained by their static design and lack of task-specific feedback. In this study, we propose a novel computational strategy inspired by molecular design that constructs molecules with targeted properties. Languages are modeled as nodes in an undirected graph, with edges representing the transfer strength. This language molecule is optimized via Reinforcement Learning to adjust edge connections and weights to enhance positive transfer and minimize interference, where graph clustering is applied, and clusters are then evaluated on the Named Entity Recognition and POS tagging tasks using 25 languages from the WikiANN dataset and 12 typologically diverse languages from the UDPOS dataset. Compared to linguistic and embedding-based language clustering baselines, our method yields substantial improvements, especially for low-resource languages, with some showing over 35% increase in F1 score, while high-resource languages benefit moderately, confirming reduced transfer–interference trade-off. Our atom–language model offers a novel path for multilingual learning, inspired by molecular principles from physical sciences. Full article

Objectives: To address the difficulty of data sharing under privacy constraints and the performance degradation of conventional federated models caused by pronounced inter-client data heterogeneity in rolling bearing remaining useful life prediction, an FDG-based framework is developed for this task. Methods: The proposed framework jointly optimizes client-side feature learning and server-side aggregation. On the client side, a domain-adversarial learning mechanism together with a gradient reversal strategy is introduced to suppress domain-related information in degradation representations and enhance domain-invariant feature learning. On the server side, a distribution-aware dynamic aggregation strategy is designed to adaptively assign aggregation weights by jointly considering client predictive performance and feature distribution discrepancies, thereby mitigating the adverse effects of non-IID data on model aggregation. Conclusions: A federated training scenario is constructed using the PHM 2012 and XJTU-SY datasets, which involve two different bearing types. Experimental results show that, without requiring raw data to leave local clients, the proposed framework improves the accuracy and generalization capability of rolling bearing remaining useful life prediction. Full article

With the scaling down of integrated circuit dimensions and the increasing complexity of transistor structures, the role of etching in manufacturing has become increasingly critical. We propose an etching simulation approach based on a video generation model, which models the evolution of the etching process as a video generation task. By embedding frames into quantized latent codeword representations using VQ-VAE (Vector Quantized Variational Autoencoder), injecting physical conditions with a CLIP projection layer, and leveraging a temporal autoregressive prediction model, we propose a generative model of the etching process. We validate the effectiveness of our model on both simulated and experimental data. Our approach achieves a 6000× speedup over the Monte Carlo method while reducing the simulation MAE (Mean Absolute Error) by 14.4% compared with the state-of-the-art video model. Furthermore, results generated by our video-based model show strong agreement with experimental data. Full article

Background: Accurate mortality prediction remains a major challenge in public health due to the complex interactions among demographic, socioeconomic, behavioral, and medical factors. This problem is particularly relevant for identifying high-risk groups and improving preventive healthcare strategies. While existing studies demonstrate strong predictive performance, they mainly rely on clinically structured data and focus on model performance. Challenges such as misclassification and atypical cases remain less explored. Methods: Using the Integrated Public Use Microdata Series National Health Interview Survey (IPUMS-NHIS) 2010 and 2015 datasets (193,765 records, 104 features), this study investigates mortality prediction through comparative Machine Learning. Data preprocessing included feature engineering, categorical encoding, and removal of missing entries. Class imbalance was addressed using SMOTE and SMOTE-ENN resampling, followed by hyperparameter tuning. Three models—Logistic Regression, Random Forest, and XGBoost—were trained to classify mortality, with recall prioritized to ensure accurate identification of deceased cases. Results: Results showed that XGBoost achieved the best performance (Recall = 69%, F1 = 0.39, AUC = 0.92), outperforming other models in balancing sensitivity and specificity. Feature importance and permutation analyses highlighted age, employment status, self-reported health, and lifestyle indicators as key predictors. Misclassification analysis combined with Isolation Forest revealed atypical profiles not captured by standard models. Conclusions: The findings underscore XGBoost’s effectiveness and demonstrate the value of integrating anomaly detection with classification to improve mortality prediction and inform public health planning. Full article