Streptococcus pneumoniae (Spn) and Streptococcus pyogenes (Spy) cause many invasive and noninvasive diseases responsible for high morbidity and mortality worldwide. Safe, efficacious and affordable vaccines could have a significant, positive impact o...
Pyrazoles are five-membered heterocyclic compounds that contain nitrogen. They are an important class of compounds for drug development; thus, they have attracted much attention. In the meantime, pyrazole derivatives have been synthesized as target s...
Even though ocean waves around the world are known to contain high and dense amounts of energy, wave energy harvesters are still not as mature as other forms of renewable energy harvesting devices, especially when it comes to commercialization, mass...
Extramammary Paget’s disease (EMPD) is a rare neoplasm that usually develops in apocrine gland-bearing areas, such as the vulva, scrotum, and penis. EMPD may present with a focal, multifocal, or an ectopic lesion. Clinically, EMPD lesions often exhib...
With the increasing world population, demand for industrialization has also increased to fulfill humans’ living standards. Fungi are considered a source of essential constituents to produce the biocatalytic enzymes, including amylases, protease...
Despite the growing interest in the field, the overall impact of augmented reality (AR) and virtual reality (VR) on mathematics learning remains unclear, with previous studies reporting mixed results. Moreover, to date, no systematic review has evalu...
Gemcitabine is a nucleoside analog that has been used widely as an anticancer drug for the treatment of a variety of conditions, including ovarian, bladder, non-small-cell lung, pancreatic, and breast cancer. However, enzymatic deamination, fast syst...
Photovoltaic power generation (PV) has significantly grown in recent years and it is perceived as one of the key strategies to reach carbon neutrality. Due to a low power density, PV requires much space, which may limit PV expansion in the future. Pl...
Product miniaturization is a trend for facilitating product usage, enabling product functions to be implemented in microscale geometries, and aimed at reducing product weight, volume, cost and pollution. Driven by ongoing miniaturization in diverse a...
Background: The design and development of prodrugs is the most common and effective strategy to overcome pharmacokinetic and pharmacodynamic drawbacks of active drugs. A respected number of prodrugs have been reached the drugs market throughout histo...
Optofluidics represents the interaction of light and fluids on a chip that integrates microfluidics and optics, which provides a promising optical platform for manipulating and analyzing fluid samples. Recent years have witnessed a substantial growth...
In this review, we focused on recent efforts in the design and development of materials with biomimetic properties. Innovative methods promise to emulate cell microenvironments and tissue functions, but many aspects regarding cellular communication,...
Viral proteases are an important target for drug development, since they can modulate vital pathways in viral replication, maturation, assembly and cell entry. With the (re)appearance of several new viruses responsible for causing diseases in humans,...
Glycoconjugate vaccines, consisting of a protein component covalently linked to a glycan antigen, have led to a significant reduction in the global occurrence of bacterial meningitis and pneumonia. They provide robust, lasting immunity in all age gro...
With the rapid development of society in recent decades, the wearable sensor has attracted attention for motion-based health care and artificial applications. However, there are still many limitations to applying them in real life, particularly the i...
Thiophenol (PhSH) belongs to a class of highly reactive and toxic aromatic thiols with widespread applications in the chemical industry for preparing pesticides, polymers, and pharmaceuticals. In this review, we comprehensively summarize recent progr...
Metallic glasses are known for their mechanical properties but lack plasticity. This could be prevented by combining them with other materials or by inducing a second phase to form a composite. These composites have enhanced thermo-physical propertie...
Online parameter estimation is essential for improving the control performance, efficiency, and reliability of permanent magnet synchronous machine (PMSM) drives. Numerous parameter estimation methods have been proposed for both position sensor-based...
The interest in zirconium-89 (89Zr) as a positron-emitting radionuclide has grown considerably over the last decade due to its standardized production, long half-life of 78.2 h, favorable decay characteristics for positron emission tomography (PET) i...
One of the fastest-expanding study areas in optics over the past decade has been metasurfaces (MSs). These subwavelength meta-atom-based ultrathin arrays have been developed for a broad range of functions, including lenses, polarization control, holo...
Recently, the application of cryogenic hoses in the field of cryogenic media has become a hot topic, especially in the industry of offshore liquefied natural gas and aerospace field. However, the structure of cryogenic hoses is complex, and reasonabl...
Currently, power electronics and AC machine drive systems are employed in numerous areas, such as in industrial processes, consumer electronics, electric vehicles (EVs), renewable-energy-source (RES)-based distributed generation (DG) systems, and ele...
We overview recent research trends in cancer genomics, bioinformatics tools development and medical genetics, based on results discussed in papers collections “Medical Genetics, Genomics and Bioinformatics” (https://www [...]
Surface-enhanced Raman scattering (SERS) is a cutting-edge technique for highly sensitive analysis of chemicals and molecules. Traditional SERS-active nanostructures are constructed on rigid substrates where the nanogaps providing hot-spots of Raman...
Polydopamine (PDA), as a mussel-inspired material, exhibits numerous favorable performance characteristics, such as a simple preparation process, prominent photothermal transfer efficiency, excellent biocompatibility, outstanding drug binding ability...
Nano-engineered medical products first appeared in the last decade. The current research in this area focuses on developing safe drugs with minimal adverse effects associated with the pharmacologically active cargo. Transdermal drug delivery, an alte...
The development of epoxy resins is mainly dependent on non-renewable petroleum resources, commonly diglycidyl ether bisphenol A (DGEBA)-type epoxy monomers. Most raw materials of these thermoset resins are toxic to the health of human beings. To alle...
MKK4 (mitogen-activated protein kinase kinase 4; also referred to as MEK4) is a dual-specificity protein kinase that phosphorylates and regulates both JNK (c-Jun N-terminal kinase) and p38 MAPK (p38 mitogen-activated protein kinase) signaling pathway...
The decapeptide gonadotropin-releasing hormone, also referred to as luteinizing hormone-releasing hormone with the sequence (pGlu-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pro-Gly-NH2) plays an important role in regulating the reproductive system. It stimulates di...
During the last decade there has been a growing interest in glycoimmunology, a relatively new research field dealing with the specific interactions of carbohydrates with the immune system. Pathogens’ cell surfaces are covered by a thick layer o...
The present article is an introductory paper in this special issue on synthetic aperture radar (SAR). A short review is presented on the recent trend and development of SAR and related techniques with selected topics, including the fields of applicat...
Foot-and-mouth disease (FMD) is a serious disease affecting the global graziery industry. Once an epidemic occurs, it can lead to economic and trade stagnation. In recent decades, FMD has been effectively controlled and even successfully eradicated i...
Aflatoxin B1 (AFB1) is one of the most frequently-found mycotoxins in contaminated food. As the content of mycotoxins is particularly low in food, the development of probes to detect AFB1 in foods with high sensitivity and selectivity is an urgent so...
The optimal treatment for hepatocellular carcinoma (HCC) should be selected based on tumor conditions, liver functional reserve, and performance status. Surgical treatment, such as liver resection and liver transplantation, is the most favorable trea...
The impact of malaria on global health has continually prompted the need to develop effective diagnostic strategies. In malaria endemic regions, routine diagnosis is hampered by technical and infrastructural challenges to laboratories. These laborato...
Extensive research and development in the production of nanocellulose production, a green, bio-based, and renewable biomaterial has paved the way for the development of advanced functional materials for a multitude of applications. From a membrane te...
Monoacylglycerol lipase (MAGL) is a key enzyme at the interface between the endocannabinoid system and lipid metabolism, playing a pivotal role in the hydrolysis of the endocannabinoid 2-arachidonoylglycerol and in the regulation of lipid mediators i...
Intermittent renewable energy requires a powerful energy storage system to smoothen the relationship between power generation and power consumption. Due to the rapidly rising price of Li resources, the development of Li-ion batteries (LIBs) has been...
Inspiring development in optical imaging enables great applications in the science and engineering industry, especially in the medical imaging area. Photonic time-stretch imaging is one emerging innovation that attracted a wide range of attention due...
This Special Issue, entitled “Recent Advances in Oral Drug Delivery Development”, aims to demonstrate new advances and future trends in the field of oral drug delivery [...]
Diabetic retinopathy (DR) is a complication of diabetes that exists throughout the world. DR occurs due to a high ratio of glucose in the blood, which causes alterations in the retinal microvasculature. Without preemptive symptoms of DR, it leads to...
Recruitment of mural cells to the vascular wall is essential for forming the vasculature as well as maintaining proper vascular functions. In recent years, zebrafish genetic tools for mural cell biology have improved substantially. Fluorescently labe...
A dietary prebiotic is defined as ‘a substrate that is selectively utilized by host microorganisms conferring a health benefit’. Although this definition evolved concomitantly with the knowledge and technological developments that accrued in the last...
In recent years, owing to the continuous development of polymer nanofiber manufacturing technology, various nanofibers with different structural characteristics have emerged, allowing their application in the field of sensing to continually expand. I...
The Epstein–Barr virus (EBV) is the first human herpesvirus identified as an oncogenic agent, with approximately 95% of adults worldwide being latently infected. EBV infection is associated with multiple diseases, including nasopharyngeal carci...
RNA therapeutics have undergone remarkable evolution since their inception in the late 1970s, revolutionizing medicine by offering new possibilities for treating previously intractable diseases. The field encompasses various modalities, including ant...
The emergence and rapid spread of Zika virus (ZIKV) on a global scale as well as the establishment of a causal link between Zika infection and congenital syndrome and neurological disorders triggered unprecedented efforts towards the development of a...
Recently, due to the coronavirus pandemic, the need for early diagnosis of infectious diseases, including viruses, is emerging. Though early diagnosis is essential to prevent infection and progression to severe illness, there are few technologies tha...
Tilapia tilapinevirus (or tilapia lake virus, TiLV) is a recently emerging virus associated with a novel disease affecting and decimating tilapia populations around the world. Since its initial identification, TiLV has been reported in 17 countries,...
Kesterite Cu2ZnSnS4 (CZTS) has attracted attention as an earth-abundant alternative to commercially successful CIGS solar cells. CZTS exhibits decent optoelectrical properties while having excellent stability on top of being an earth-abundant, low-co...
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