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Recent Development of Aptamer Sensors for the Quantification of Aflatoxin B1

School of Chemistry and Chemical Engineering, Research Institute of Resource Chemical Industry, Lingnan Normal University, Zhanjiang 524048, China
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Appl. Sci. 2019, 9(11), 2364; https://doi.org/10.3390/app9112364
Received: 29 April 2019 / Revised: 29 May 2019 / Accepted: 31 May 2019 / Published: 10 June 2019
(This article belongs to the Section Chemistry)
Aflatoxin B1 (AFB1) is one of the most frequently-found mycotoxins in contaminated food. As the content of mycotoxins is particularly low in food, the development of probes to detect AFB1 in foods with high sensitivity and selectivity is an urgent social need for the evaluation of food quality. Numerous techniques have been developed to monitor AFB1. Nevertheless, most of them require cumbersome, labor-consuming, and sophisticated instruments, which have limited their application. An aptamer is a single, short nucleic acid sequence that is capable of recognizing different targets. Owing to their unique properties, aptamers have been considered as alternatives to antibodies. Aptasensors are considered to be an emerging strategy for the quantification of aflatoxin B1 with high selectivity and sensitivity. In this review, we summarize recent developments in colormetric, electrochemical, SERS, and fluorescent aptasensors for the quantification of AFB1. Finally, the perspectives and current challenges of aptasensors for AFB1 are outlined. View Full-Text
Keywords: aflatoxin B1; aptamer; detection aflatoxin B1; aptamer; detection
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Jia, Y.; Zhou, G.; Liu, P.; Li, Z.; Yu, B. Recent Development of Aptamer Sensors for the Quantification of Aflatoxin B1. Appl. Sci. 2019, 9, 2364.

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