Because of their importance in a variety of interdisciplinary study domains, Schiff-base ligands have performed a significant role in the evolution of contemporary coordination chemistry. This almost-comprehensive review covers all the aspects and pr...
The zinc(II) ion forms stable complexes with a wide variety of ligands, but those related to Schiff-bases are among the most largely investigated. This review deals with the peculiar aggregation characteristics of Zn(II) Schiff-base complexes from te...
In this work, nanosized Cu and Ni Schiff-base complexes, namely ahpvCu, ahpnbCu, and ahpvNi, incorporating imine ligands derived from the condensation of 2-amino-3-hydroxypyridine, with either 3-methoxysalicylaldehyde (ahpv) or 4-nitrobenzaldehyde (a...
The ligand named 1-(3-chlorophenyl)-N-(pyridine-2-yl)methanimine Schiff base was obtained with the method of mixing 2-amino pyridine with 3-chloro benzaldehyde in methanol as an initial material. Transition metals, like Cu(II), were added to the prep...
Four dioxidovanadium(V) complexes with Schiff-base ligands based on 2-hydroxybenzhydrazide with four different substituted salicylaldehydes (5-chlorosalicylaldehyde, 3,5-dichlorosalicylaldehyde, 5-nitrosalicylaldehyde, 3-bromo-5-chlorosalicylaldehyde...
Two potentially heptadentate (N4O3) tripodal Schiff-base ligands: tris(3-(salicylideneimino)propyl)amine (H3L1) and tris(3-(4’-hydroxysalicylideneimino)-propyl)amine (H3L2) have been prepared and characterized by various spectroscopic methods (IR, FA...
Since their development in the 1930s, Schiff-base complexes have played an important role in the field of coordination chemistry. Here, we report the synthetic, spectral, structural, magnetic and electrochemical studies of two new pentacoordinated ne...
Schiff-Base complexes of bis-5-phenylazosalicylaldehyde ethylenediimine and bis-5-phenylazosalicylaldehyde-O-phenylenediimine ligands with Co(II) (I and II) have been synthesized and characterized by their IR spectra and elemental analyses. These com...
Even 155 years after their first synthesis, Schiff bases continue to surprise inorganic chemists. Schiff-base ligands have played a major role in the development of modern coordination chemistry because of their relevance to a number of interdiscipli...
A new Schiff base, 4-((1E,2E)-3-(furan-2-yl)allylidene)amino)-N-(5-methylisoxazol-3-yl) benzene-sulfonamide (L), was synthesized by thermal condensation of 3-(2-furyl)acrolein and sulfamethoxazole (SMX), and the furan Schiff base (L) was converted to...
This paper explores a dual inhibition of main protease (Mpro) and nonstructural protein 10/nonstructural protein 16 (NSP16) methyltransferase complex as the key targets for COVID-19 therapy. These are based on the new Schiff-base ligand that was obta...
A series of five neutral mononuclear lanthanide complexes [Ln(HL)(L)] (Ln = Dy3+, Ho3+ Er3+ and Tb3+) with rigid pentadentate N3O2-type Schiff base ligands, H2LH (1-Dy, 3-Ho, 4-Er and 6-Tb complexes) or H2LOCH3, (2-Dy complex) has been synthesized by...
This review summarizes the structural characteristics and physicochemical properties of chiral 4f and 3d-4f complexes based on enantiopure salen-type Schiff base ligands. The chirality originates from the enantiopure diamines and is imparted to the S...
Schiff bases are organic compounds that are often used as ligands in metal complexes. In addition to the C=N double bond, which is characteristic of Schiff bases, intermolecular hydrogen bonds are frequently observed in both the twisting of planar su...
To identify the effects of halogen bonding in the architecture of Schiff base complex supramolecular networks, we introduced halogenated Schiff-base 3-Br-5-Cl-salen as ligand and isolated a new salen-type manganese(III) complex [MnIII(Cl)(H2O)(3-Br-5...
Schiff bases have played significant roles in the development of inorganic or coordination chemistry. Three Schiff base (NB, CB and HB) ligands, prepared for the reaction of 2-amino-6-methoxy-benzothiazole with 2-Nitrobenzaldehyde, 2-chlorobenzaldehy...
According to the World Health Organization, breast cancer is the cancer that affects the largest number of people each year, especially women. Millions of women are diagnosed with it each year, and hundreds of thousands die from it. Research into new...
The synthesis, crystal structure, and magnetic properties of three new mononuclear complexes [Fe(R-LA)(L1)](BPh4), where R-LA2− is a doubly deprotonated pentadentate Schiff base ligand and L1 is a monodentate benzimidazole or furopyridine ligan...
Chemistry of Schiff base (SB) ligands began in 1864 due to the discovery made by Hugo Schiff (Schiff, H., Justus Liebigs Ann. der Chemie 1864, 131 (1), 118–119). However, there is still a vivid interest in coordination compounds based on imine...
A pioneering research on a self-assembly of the magneto-anisotropic module [Re(CN)7]3− with the Mn(III) complexes involving Salen type (N,N′-ethylenebis(salicylideneiminate)) Schiff base (SB) ligands was performed using the known [Mn(3MeOSalen)(H2O)2...
The new homodinuclear complexes of the general formula [Ln2L3(NO3)3] (where HL is newly synthesized 2-((2-(benzoxazol-2-yl)-2-methylhydrazono)methyl)phenol and Ln = Sm3+ (1), Eu3+ (2), Tb3+ (3a, 3b), Dy3+ (4), Ho3+ (5), Er3+ (6), Tm3+ (7), Yb3+ (8)),...
DNA has become the target of metal complexes in cancer drug discovery. Due to the side effects of widely known cisplatin and its derivative compounds, alternative metal-based drug discovery studies are still ongoing. In this study, the DNA-binding ab...
New Co(II), Ni(II), and Cu(II) complexes were synthesized with the Schiff base ligand obtained by the condensation of sulfathiazole with salicylaldehyde. Their characterization was performed by elemental analysis, molar conductance, spectroscopic tec...
Molecular orientation of dyes must be one of the important factors for designing dye-sensitized solar cells (DSSC). As model systems, we have prepared new hybrid materials composed of azobenzene (AZ) and chiral Schiff base Cu(II) complexes (pn(S)Cu a...
Cancer continues to be one of the leading causes of death, according to the World Health Organization, and chemotherapy is its principal treatment. Organometallic complexes with copper (II) and zinc (II) with Schiff bases as ligand, capable of intera...
In this study, two simple Schiff base copper complexes [Cu(H2O)2(HL)]·2H2O (Complex 1) (H3L = 2-OH-4-(OH)-C6H2CH=NCH2CO2H) and [Cu(py)2(HL)] (Complex 2) (Py = pyridine) were initially achieved and authenticated by single-crystal X-ray structure analy...
Composite materials very often provide new catalytic, optical or other physicochemical properties not observed for each component separately. Photofunctions in hybrid systems are an interesting topic of great importance for industry. This review pres...
The present work describes the chemical preparation of Schiff bases derived from 4,4′-diaminodiphenyl sulfone (L1–L5) and their Co(II) metal complexes. The evaluation of antimicrobial and anticancer activities against MCF-7 cell line and...
New PdII–LnIII–PdII complexes of hexadentate N2O4 Schiff base ligand (H4L: N,N′-bis(2,3-dihydroxybenzylidene)-1,3-diamino-2,2-dimethylpropane) with Eu (1), Tb (2), Er (3) and Yb (4) ([Pd2Eu(H2L)2NO3](NO3)2∙2H2O∙2CH3OH 1, [Pd2Ln(H2L)...
A novel Schiff base ligand derived from 2,2'-bis(p-methoxyphenylamine) and salicylicaldehyde and its transition metal complexes with Cu (Ⅱ), Co (Ⅱ) and Mn (Ⅱ) have been synthesized. Their spectral properties and electrochemical behavior were investig...
Amino acid Schiff base Cu(II) complexes were synthesized under microwave irradiation using methanol as a solvent, to maximize the best conditions to obtain the attained compounds, containing aromatics possessing no, one or two chlorine atoms. The com...
Metal-based drugs, including lanthanide complexes, have been extremely effective in clinical treatments against various diseases and have raised major interest in recent decades. Hence, in this work, a series of lanthanum (III) and cerium (III) compl...
The interactions with calf thymus DNA (CT-DNA) of three Schiff bases formed by the condensation of hesperetin with benzohydrazide (HHSB or L1H3), isoniazid (HIN or L2H3), or thiosemicarbazide (HTSC or L3H3) and their CuII complexes (CuHHSB, CuHIN, an...
The reduction of 4-nitrophenol to 4-aminophenol by sodium borohydride was used as a model to test the catalytic activity of copper(II) complexes containing N,O-chelating Schiff base ligands. In this study, a series of copper(II) complexes containing...
A mixed-valent trinuclear complex with 1,3-bis(5-chlorosalicylideneamino)-2-propanol (H3clsalpr) was synthesized, and the crystal structure was determined by the single-crystal X-ray diffraction method at 90 K. The molecule is a trinuclear CoIII-CoII...
Four new Schiff base functionalized 1,2,3-triazolylidene nickel complexes, [Ni-(L1NHC)2](PF6)2; 3, [Ni-(L2NHC)2](PF6)2; 4, [Ni-(L3NHC)](PF6)2; 7 and [Ni-(L4NHC)](PF6)2; 8, (where L1NHC = (E)-3-methyl-1-propyl-4-(2-(((2-(pyridin-2-yl)ethyl)imino)methy...
Five transition metal(II) complexes, [ML2Cl2] 1~5, were synthesized from the reaction of MCl2·nH2O (M = Mn, Co, Ni, Cu, Cd) and the Schiff base ligand 2-[(4-methylphenylimino)methyl]-6-methoxyphenol (C15H15NO2, L), obtained by condensation of o-vanil...
The reaction of organic molecules mediated by a metal center (template synthesis) can result in a final connectivity that may differ from the one obtained in the absence of the metal. The condensation of carbonyl fragments with primary amines form C=...
A novel Schiff base, ethyl 4-[(E)-(2-hydroxy-4-methoxyphenyl)methylene-amino]benzoate (HL), was prepared and structurally characterized on the basis of elemental analyses, 1H NMR, 13C NMR, UV-Vis and IR spectral data. Six new copper(II) complexes, [C...
Coordination compounds with transition metals, especially of molybdenum, are promising cytoprotective agents. In this work, we analyzed the changes in HT-22 cell viability under the influence of molybdenum(VI) Schiff base complexes per se or in cellu...
Microdroplets generated in microfluidic devices are attracting attention as a new chemical reaction field and are expected to improve reactivity. One of the effects of microscaling is that the ratio of the force that acts on the diffusion and movemen...
Salphen-type ligands are known to form stable chelate complexes with different metals. Those metal complexes with Pt(II), Pd(II), Ni(II), Cu(II), Zn(II), etc., are capable of selective G-quadruplex DNA binding and therefore are promising anticancer a...
The preparation of non-symmetric Schiff base ligands possessing one oxime function that is associated to a second function such as pyrrole or phenol function is first described. These ligands, which possess inner N4 or N3O coordination sites, allow f...
In this study, we report the cytotoxicity of a newly synthesized Schiff base HL ((E)-2-ethoxy-6((pyren-1-ylimino)methyl)phenol) and its derived metal complexes (Zn(II), Cu(II), Co(II), Cr(III), and Fe(III)) along with their structural characterizatio...
Their demonstrable bioactive characteristics, coupled with their wide structural diversity and coordination versatility, render Schiff bases and their coordination complexes biologically active compounds demonstrating outstanding properties. This res...
The Schiff base derivative (Ch-8Q) of chitosan (Ch) and 8-hydroxyquinoline-2-carboxaldehyde (8QCHO) was prepared and fibrous mats were obtained by the electrospinning of Ch-8Q/polylactide (PLA) blend solutions in trifluoroacetic acid (TFA). Complexes...
Salophen-type Schiff base ligands derived from salicylaldehyde and naphthalene aldehydes were synthesized and coordinated to Ni(II) to obtain three nickel complexes (NiL1–NiL3), which were evaluated as heterogeneous electrocatalysts for the met...
Nitric oxide (NO), the smallest signalling molecule known in the human body, keeps blood vessels dilated, controls blood pressure, and has numerous other health regulatory effects. The use of Schiff base complexes incorporated onto electrodes to make...
Salen-type metal complexes have been actively studied for their nonlinear optical (NLO) properties, and push-pull compounds with charge asymmetry generated by electron releasing and withdrawing groups have shown promising results. As a continuation o...
The asymmetrical tripodal tetraamine ligand N[(CH2)3NH2]2[(CH2)2NH2] (ppe) was condensed with 2-acetylpyridine in the presence of nickel(II) ion. In ethanolwater solution the reaction stops after the first stage of condensation, and a new nickel(II)...
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