Synthesis and Structural Studies of Potential Anticancer Drugs
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Pharmacology".
Deadline for manuscript submissions: 31 December 2025 | Viewed by 72
Special Issue Editor
Interests: carbohydrates; synthesis and analysis of sugar derivatives; vancomycin and its derivatives; sugar hydrazides; cationic sugar compounds; biological activity of sugar derivatives
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Special Issue Information
Dear Colleagues,
Cancer is defined as a disease in which cells begin to grow in an uncontrolled way and spread to other parts of the body. There are over 100 known varieties of cancer, and their names are usually derived from the organ or tissue in which they form. This number of varieties makes their diagnosis and treatment much more difficult. Cancer is one of the most deadly diseases in the world, and the forecasts are not optimistic. It is estimated that in 2050, the number of cancer cases worldwide will increase to 33 million (an increase of over 60% compared to 2022) and the number of cancer-related deaths will reach over 18 million, which will be almost a 90% increase compared to 2022. This state of affairs means that many research centers are conducting intensive work on better diagnostics, allowing for earlier detection of the disease, and on new, more effective therapies. One of the important elements of new therapies are new drugs that would be characterized by greater effectiveness and selectivity, and on the other hand, lower toxicity in relation to healthy cells.
In this Special Issue “Synthesis and Structural Studies of Potential Anticancer Drugs”, we would like to focus on the synthesis, structural studies, and biological activity of potential anticancer drugs. We would like to gather in one place new valuable articles contributing to the synthesis of new compounds with anticancer activity, and studies of their structure using spectroscopic, X-ray, and computational methods. An important element is also the possible dependencies of anticancer activity–structure. Review articles on these topics will also provide an important complementary element.
Prof. Dr. Janusz Madaj
Guest Editor
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Keywords
- medicinal chemistry
- drug discovery
- design and synthesis of bioactive compounds
- molecular modeling
- X-ray crystallography
- structure–activity relationships
- structure-based drug design
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