Copper is a critical metal nutrient required by marine microalgae but may be toxic when supplied in excess. Maintaining an optimal intracellular Cu content is thus fundamentally necessary for microalgae and relies on cellular regulatory metabolisms a...
Copper (Cu) is a critical element for cancer cell proliferation and considerably accumulates in the nucleus. 64Cu2+ is an anticancer radiopharmaceutical that targets the copper requirement of cancer cells. However, intravenously injected 64Cu2+ ions...
This study evaluated the optimal dietary copper (Cu) levels and their effects on growth performance, body composition, and antioxidant capacity in juvenile largemouth bass (Micropterus salmoides). A total of 360 fish (initial average weight (1.67 &pl...
Former mine sites can provide habitat for many rare specialised bryophyte species that have adapted to metal-rich soil conditions that are toxic to most other plant species. Some of the bryophyte species found in this habitat are facultative metallop...
Chicken meat is the most widely consumed meat globally, with Australia alone reporting a per capita consumption of 53 kg/person/year. Amino acids and microminerals are essential to poultry nutrition, supporting growth performance and health in broile...
The use of copper complexes as pharmacotherapy represents an emerging strategy with multiple therapeutic advantages, including their enhanced bioavailability, antimicrobial activity, and ability to participate in diverse cellular processes. These mol...
Ensuring adequate copper supplementation in ruminants is a challenging task due to the complexity of copper metabolism in these animals. The three-way interaction between copper, molybdenum and sulphur (Cu-Mo-S) in the rumen makes ruminants, particul...
Copper is essential for the stability and activity of cytochrome c oxidase (CcO), the terminal enzyme of the mitochondrial respiratory chain. Copper is bound to COX1 and COX2, two core subunits of CcO, forming the CuB and CuA sites, respectively. Bio...
Copper is an essential cofactor for aerobic respiration, since it is required as a redox cofactor in Cytochrome c Oxidase (COX). This ancient and highly conserved enzymatic complex from the family of heme-copper oxidase possesses two copper sites: Cu...
Nanotechnology has ushered in a new era of medical innovation, offering unique solutions to longstanding healthcare challenges. Among nanomaterials, copper and copper oxide nanoparticles stand out as promising candidates for a multitude of medical ap...
Copper ions (i.e., copper) are a critical part of several cellular processes, but tight regulation of copper levels and trafficking are required to keep the cell protected from this highly reactive transition metal. Cu, Zn superoxide dismutase (Sod1)...
Physiologically relevant iron-copper interactions have been frequently documented. For example, excess enteral iron inhibits copper absorption in laboratory rodents and humans. Whether this also occurs during pregnancy and lactation, when iron supple...
Chemical imaging of corrosion processes involving copper species using scanning electrochemical microscopy has been hampered by the lack of soluble oxidation states for copper that can be achieved by amperometric conversion at the tip. Indeed, the on...
Copper, the highly toxic micronutrient, plays two essential roles: it is a catalytic and structural cofactor for Cu-dependent enzymes, and it acts as a secondary messenger. In the cells, copper is imported by CTR1 (high-affinity copper transporter 1)...
Copper has been used as a biocide for more than one century, in various applications. However, as a biocide, copper, both metallic, as a salt or as copper oxide particles, is toxic not only to its intended targets, mainly bacteria and fungi, but also...
The surge in electric vehicles (EVs) and their electrical appliances requires highly efficient, lightweight electrical machines with better performance. However, conventional wire used for electrical machine windings have certain limits to the curren...
Copper-catalyzed azide–alkyne cycloaddition click (CuAAC) reaction is widely used to synthesize drug candidates and other biomolecule classes. Homogeneous catalysts, which consist of copper coordinated to a ligand framework, have been optimized...
Streptococcus suis is a zoonotic pathogen that causes great economic losses to the swine industry and severe threats to public health. A better understanding of its physiology would contribute to the control of its infections. Although copper is an e...
In order to maximize the utilization value of copper slag, a process of smelting copper–iron alloy with copper slag is proposed here. The reduction kinetics of copper slag by H2 are studied in this paper. The main phases of the copper slag were...
As a structural and catalytic cofactor, copper is involved in many biological pathways and is required for the biochemistry of all living organisms. However, excess intracellular copper can induce cell death due to its potential to catalyze the gener...
Copper oxide ore is an important copper ore resource. For a certain copper oxide ore in Yunnan, China, experiments have been conducted on the grinding fineness, collector dosage, sodium sulfide dosage, inhibitor dosage, and activator dosage. The resu...
Babbitt alloys are among the most commonly used materials for sliding bearings. However, with the high speeds and heavy loads of modern machinery, as well as the demands of extreme working conditions, the temperature resistance, strength, and hardnes...
This study evaluates and compares the effectiveness of friction stir welding on aluminium and copper alloys with the aim of improving the strength of the resulting joints. The rotary friction stir welding method was chosen for its ability to produce...
Copper is a crucial cofactor that sustains multiple cellular electron-transfer reactions, making it an essential element for life. However, cytotoxic levels of copper can cause structural damage and cell death through the production of reactive oxyge...
Copper is required for aerobic respiration by Mycobacterium tuberculosis and its human host, but this essential element is toxic in abundance. Copper nutritional immunity refers to host processes that modulate levels of free copper to alternately sta...
One of the main problems in processing chalcopyrite ore with hydrometallurgical methods is its refractoriness, which is due to the formation of a layer that inhibits the contact of the ore with the leaching solution, thus reducing the dissolution rat...
Copper is widely used as antimicrobial in agriculture and medicine. Copper tolerance mechanisms of pathogenic bacteria have been proven to be required for both copper tolerance and survival during bacterial infections. Here, we determined both copper...
This article presents the methodology, description, and results of experimental studies aimed at determining the impact of the copper concentration in a carbon–metal composite contact strip on the maximum temperature of the copper contact wire...
With the proliferation of flexible electronics, the advancement of mechanically compliant thermal management systems, notably flexible heat pipes, is imperative to address evolving demands for adaptive thermal regulation in deformable device architec...
Treatment of drug-resistant forms of cancer requires consideration of their hallmark features, such as abnormal cell death mechanisms or mutations in drug-responding molecular pathways. Malignant cells differ from their normal counterparts in numerou...
Thin and ultrathin carbon films reduce the laser energy required for copper powder fusion in selective laser melting (SLM). The low absorption of infrared (IR) radiation and its excellent thermal conductivity leads to an intricate combination of proc...
In humans, copper is an important micronutrient because it is a cofactor of ubiquitous and brain-specific cuproenzymes, as well as a secondary messenger. Failure of the mechanisms supporting copper balance leads to the development of neurodegenerativ...
Human antioxidant protein 1 (Atox1) is a small cytosolic protein with an essential role in copper homeostasis. Atox1 functions as a copper carrier facilitating copper transfer to the secretory pathway. This process is required for activation of coppe...
Copper is an essential element in the diet of mammals, including humans. It plays an important role in the physiological regulation of various enzymes and is consequently involved in several biological processes such as angiogenesis, oxidative stress...
Inductive Power Transfer (IPT) is evolving fast in many domains, but its efficiency, its extensive resource requirements, and its cost remain crucial problems for its development. Although the inverter is mainly responsible for its cost and material...
Integration of sensors in textile garments requires the development of flexible conductive structures. In this work, cellulose-based woven lyocell fabrics were coated with copper during an electroless step, produced at 0.0284 M copper sulfate pentahy...
The development of microelectronics results in higher demand for copper microwires and thin foils. Higher demand requires conducting research to obtain knowledge on the influence of extreme plastic deformation on materials’ susceptibility to pl...
In the present work the effect of alkaline sulfide leaching (ASL) on the extraction of copper and zinc from low-grade copper concentrate containing chalcopyrite, tennantite, sphalerite, and pyrite during batch and continuous bioleaching experiments w...
In this study, solar water heater was investigated using meteorological and geographical data of 129 sites over Turkey. Three different collector types were compared in terms of absorber material (copper, galvanized sheet and selective absorber). Ene...
Several countries are planning to store nuclear spent fuel in long term geological repositories, preserved by copper canisters with an iron insert. This new approach involves many challenging problems and one is to satisfy safeguards requirements: th...
In the present study, the problem of sulfuric acid recycling from spent copper plating solution was solved using a hybrid membrane technology, including diffusion dialysis and electrodialysis. A real solution from the production of copper-coated stee...
Fabricating a dissimilar-metal block with micro/nano-multilayered structures is usually used by engineers and scientists because of their excellent mechanical properties. In the current work, multilayered copper/brass blocks were effectively fabricat...
Direct-to-blister copper smelting is an important smelting process due to its short process, low energy consumption and environmental protection. This study attempts to use high-grade chalcocite as the raw material for direct-to-blister smelting to r...
Polyphenols have gained increasing attention for their therapeutic potential, particularly in conditions like cancer, due to their established antioxidant and anti-inflammatory properties. Recent research highlights their ability to bind to transitio...
Copper is an essential trace element, yet chronic copper exposure can lead to toxicity in humans, and high levels of copper have been found in the blood or tumors of patients with various forms of cancer and may affect cancer severity and response to...
Recycling of electrical cable waste requires a separation between the metal and the insulating material. The objective of this work was to separate the copper from the plastic in electrical cable waste previously ground below 2 mm, using jigging, sha...
The removal of copper from wastewater of mine origin requires the use of an appropriate method. Sorption methods are considered to be one of the best solutions for removing copper from industrial wastewater at low levels. Metal(IV) phosphates have be...
Copper is a vital micronutrient for animals and plants acting as a crucial cofactor in the synthesis of numerous metabolic enzymes and contributing to mitochondrial respiration, metabolism, oxido-reductive reactions, signal transmission, and oxidativ...
Copper and zinc are micronutrients that play a crucial role in many cellular pathways, act as cofactors in enzymatic systems, and hence, modulate enzyme activity. The regulation of these elements in homeostasis is precisely controlled by various mech...
The objective of this work is the enhancement of metal-to-metal bonding to provide high thermal conductivity together with electrical insulation, to be used as heat sinks at room and cryogenic temperatures. High thermal conductive metal (copper) and...
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