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3,735 Results Found

  • Article
  • Open Access
3 Citations
3,110 Views
11 Pages

On the Classification of Polyhedral Links

  • Naohiro Wakayama and
  • Koya Shimokawa

17 August 2022

Knots and links are ubiquitous in chemical systems. Their structure can be responsible for a variety of physical and chemical properties, making them very important in materials development. In this article, we analyze the topological structures of i...

(This article belongs to the Special Issue Topological Methods in Chemistry and Molecular Biology)
  • Review
  • Open Access
42 Citations
9,240 Views
21 Pages

Targeting Telomerase and ATRX/DAXX Inducing Tumor Senescence and Apoptosis in the Malignant Glioma

  • Hueng-Chuen Fan,
  • Chuan-Mu Chen,
  • Ching-Shiang Chi,
  • Jeng-Dau Tsai,
  • Kuo-Liang Chiang,
  • Yu-Kang Chang,
  • Shinn-Zong Lin and
  • Horng-Jyh Harn

Glioblastoma multiforme (GBM) is a type of brain tumor that is notorious for its aggressiveness and invasiveness, and the complete removal of GBM is still not possible, even with advanced diagnostic strategies and extensive therapeutic plans. Its dis...

(This article belongs to the Special Issue Intracranial Malignancies: Molecular Insights and Therapeutic Advances)
  • Article
  • Open Access
4 Citations
3,556 Views
12 Pages

Use of Complementary and Alternative Medicine in Patients with Rare Bone Diseases and Osteoporosis

  • Roland Kocijan,
  • Amadea Medibach,
  • Lisa Lechner,
  • Judith Haschka,
  • Annemarie Kocijan,
  • Daniel Arian Kraus,
  • Jochen Zwerina and
  • Martina Behanova

13 March 2024

(1) Background: The use of complementary and alternative medicine (CAM) has seen a notable increase in popularity. However, there is an absence of data regarding the prevalence of CAM use in patients with rare bone diseases (RBDs). (2) Methods: This...

(This article belongs to the Section Nutrition and Public Health)
  • Article
  • Open Access
52 Citations
9,595 Views
12 Pages

Cross-Linked Amylose Bio-Plastic: A Transgenic-Based Compostable Plastic Alternative

  • Domenico Sagnelli,
  • Kourosh Hooshmand,
  • Gerdi Christine Kemmer,
  • Jacob J. K. Kirkensgaard,
  • Kell Mortensen,
  • Concetta Valeria L. Giosafatto,
  • Mette Holse,
  • Kim H. Hebelstrup,
  • Jinsong Bao and
  • Andreas Blennow
  • + 2 authors

30 September 2017

Bio-plastics and bio-materials are composed of natural or biomass derived polymers, offering solutions to solve immediate environmental issues. Polysaccharide-based bio-plastics represent important alternatives to conventional plastic because of thei...

(This article belongs to the Special Issue Advanced Biomaterials for Food Edible Coatings)
  • Article
  • Open Access
1 Citations
1,320 Views
19 Pages

17 November 2025

The majority of research on food webs has focused on temperate lakes, and little is known about the food web of lakes in polar regions. Subarctic lakes are particularly sensitive to climate change, which affects their stability. Therefore, the trophi...

(This article belongs to the Special Issue 15th Anniversary of Diversity—Biodiversity, Conservation and Ecology of Animals, Plants and Microorganisms)
  • Article
  • Open Access
1 Citations
2,659 Views
34 Pages

New Bioinformatic Insight into CD44: Classification of Human Variants and Structural Analysis of CD44 Targeting

  • Wiktoria A. Gerlicz,
  • Aleksandra Olczak,
  • Aneta M. Białkowska and
  • Aleksandra Twarda-Clapa

11 October 2025

The cluster of differentiation 44 (CD44) is a member of the hyaluronic acid (HA) receptor family of cell adhesion molecules. Besides HA, this transmembrane protein also serves as a receptor for other components of the extracellular matrix (ECM), incl...

(This article belongs to the Section Biochemistry)
  • Article
  • Open Access
1 Citations
3,704 Views
20 Pages

24 September 2021

High voltage electric power equipment requires rigorous regulation testing to specific standards which ensure proper and safe operation in the grid. Manufacturers conduct these tests in order to prove standard compliance and product liability. Variab...

(This article belongs to the Section F: Electrical Engineering)
  • Article
  • Open Access
1,810 Views
12 Pages

Colocalised Genetic Associations Reveal Alternative Splicing Variants as Candidate Causal Links for Breast Cancer Risk in 10 Loci

  • André Besouro-Duarte,
  • Beatriz Carrasqueiro,
  • Sofia Sousa,
  • Joana M. Xavier and
  • Ana-Teresa Maia

29 August 2024

Genome-wide association studies (GWASs) have revealed numerous loci associated with breast cancer risk, yet the precise causal variants, their impact on molecular mechanisms, and the affected genes often remain elusive. We hypothesised that specific...

(This article belongs to the Collection Regulatory and Non-Coding RNAs in Cancer Epigenetic Mechanisms)
  • Article
  • Open Access
1 Citations
7,781 Views
13 Pages

3 January 2023

Some contemporary social phenomena, despite secularization, are still linked to religion. However, this same secularization seems to have accompanied a progressive process of religious illiteracy. Therefore, the capacity to address religious inspired...

(This article belongs to the Special Issue Political Secularism and Religion)
  • Article
  • Open Access
4 Citations
3,453 Views
12 Pages

Dapsone Azo-Linked with Two Mesalazine Moieties Is a “Me-Better” Alternative to Sulfasalazine

  • Changyu Kang,
  • Jaejeong Kim,
  • Sanghyun Ju,
  • Sohee Park,
  • Jin-Wook Yoo,
  • In-Soo Yoon,
  • Min-Soo Kim and
  • Yunjin Jung

Dapsone (DpS) is an antimicrobial and antiprotozoal agent, especially used to treat leprosy. The drug shares a similar mode of action with sulfonamides. Additionally, it possesses anti-inflammatory activity, useful for treating autoimmune diseases. H...

(This article belongs to the Section Drug Targeting and Design)
  • Article
  • Open Access
30 Citations
7,246 Views
18 Pages

New technologies, specifically the internet, have over the last two decades increased the number of publications in the most diverse fields of science. Subjects related to renewable and sustainable energy are no exception. These frameworks have allow...

(This article belongs to the Special Issue Environmental Sustainability-Life Cycle Assessment-Energy and Environmental Technology)
  • Article
  • Open Access
10 Citations
3,847 Views
13 Pages

A Novel Mutation Associated with Neonatal Lethal Cardiomyopathy Leads to an Alternative Transcript Expression in the X-Linked Complex I NDUFB11 Gene

  • Guillermo Amate-García,
  • María Juliana Ballesta-Martínez,
  • Pablo Serrano-Lorenzo,
  • Rocío Garrido-Moraga,
  • Adrián González-Quintana,
  • Alberto Blázquez,
  • Juan C. Rubio,
  • Inés García-Consuegra,
  • Joaquín Arenas and
  • Miguel A. Martín
  • + 3 authors

16 January 2023

We report a neonatal patient with hypertrophic cardiomyopathy (HCM), lactic acidosis and isolated complex I deficiency. Using a customized next-generation sequencing panel, we identified a novel hemizygous variant c.338G>A in the X-linked NDUFB11...

(This article belongs to the Special Issue Mitochondria and Energy Metabolism in Rare Diseases)
  • Article
  • Open Access
10 Citations
3,777 Views
19 Pages

3 October 2022

The effect of ethynylene or ethynylene–thiophene spacers on the band gap of alternating polymers, containing 4,9-naphthothiadiazole units as an acceptor and 2,7-linked fluorene repeat units as a donor, were investigated. The Sonogashira couplin...

(This article belongs to the Section Polymer Processing and Engineering)
  • Article
  • Open Access
25 Citations
6,308 Views
24 Pages

Alternatives for the Valorization of Avocado Waste Generated in the Different Links of the Value Chain Based on a Life-Cycle Analysis Approach

  • Maria Camila Garcia-Vallejo,
  • Tatiana Agudelo Patiño,
  • Jhonny Alejandro Poveda-Giraldo,
  • Sara Piedrahita-Rodríguez and
  • Carlos Ariel Cardona Alzate

25 August 2023

This work evaluates the sustainability of small-scale biorefineries as a potential enterprise alternative to be introduced in rural areas based on experimental and simulation data. Four scenarios were evaluated: the first scenario involves the produc...

(This article belongs to the Special Issue Pretreatment and Bioconversion of Crop Residues II)
  • Article
  • Open Access
28 Citations
8,628 Views
20 Pages

On the Mechanism of Drug Release from Polysaccharide Hydrogels Cross-Linked with Magnetite Nanoparticles by Applying Alternating Magnetic Fields: the Case of DOXO Delivery

  • Marianna Uva,
  • Lorenzo Mencuccini,
  • Andrea Atrei,
  • Claudia Innocenti,
  • Elvira Fantechi,
  • Claudio Sangregorio,
  • Melania Maglio,
  • Milena Fini and
  • Rolando Barbucci

20 May 2015

The chemical, biological and physical properties of carboxymethylcellulose (CMC) hydrogels with silanized magnetite (Fe3O4) nanoparticles (NPs) as cross-linker were investigated and compared with the analogous hydrogel obtained by using 1,3-diaminop...

(This article belongs to the Special Issue Nanoparticle-Hydrogel Composites for Biomedical Applications)
  • Article
  • Open Access
11 Citations
4,328 Views
21 Pages

This study presents an evaluation of seventeen newly produced recombinant trivalent chimeric proteins (containing the same immunodominant fragment of SAG1 and SAG2 of Toxoplasma gondii antigens, and an additional immunodominant fragment of one of the...

(This article belongs to the Special Issue Parasite Biology and Host-Parasite Interactions: 2nd Edition)
  • Article
  • Open Access
18 Citations
5,412 Views
19 Pages

29 May 2020

NSIAD is a rare X-linked condition, caused by activating mutations in the AVPR2 gene coding for the vasopressin V2 receptor (V2R) associated with hyponatremia, despite undetectable plasma vasopressin levels. We have recently provided in vitro evidenc...

(This article belongs to the Special Issue Physiopathology of Signaling Transmission in Renal Diseases)
  • Review
  • Open Access
19 Citations
6,788 Views
13 Pages

Linking Endoplasmic Reticular Stress and Alternative Splicing

  • Nolan T. Carew,
  • Ashley M. Nelson,
  • Zhitao Liang,
  • Sage M. Smith and
  • Christine Milcarek

7 December 2018

RNA splicing patterns in antibody-secreting cells are shaped by endoplasmic reticulum stress, ELL2 (eleven-nineteen lysine-rich leukemia gene 2) induction, and changes in the levels of snRNAs. Endoplasmic reticulum stress induces the unfolded protein...

(This article belongs to the Special Issue Endoplasmic Reticulum Stress and Unfolded Protein Response)
  • Article
  • Open Access
2 Citations
3,922 Views
14 Pages

7 April 2023

Contemporary ecospirituality is built on a double articulation between ecology (science) and spirituality (religion) and can be intertwined with practices and beliefs stemming from neopaganism and, more broadly, an animist vision. The study presented...

(This article belongs to the Special Issue Religion, Science and Technology in Pantheism, Animism and Paganism)
  • Article
  • Open Access
1,028 Views
12 Pages

Alternative Natural Rubber Cross-Linking Utilizing a Disulfide-Containing Bismaleimide

  • Anureet Kaur,
  • Maria Tucker,
  • Keizo Akutagawa,
  • Biqiong Chen and
  • James J. C. Busfield

13 December 2025

This study explores a disulfide-selective cross-linking strategy for natural rubber (NR) to formulate elastomeric materials with engineering-relevant mechanical properties. A disulfide-containing bismaleimide (BIS) cross-linker was synthesized from c...

(This article belongs to the Special Issue Exploration and Innovation in Sustainable Rubber Performance)
  • Review
  • Open Access
31 Citations
24,437 Views
31 Pages

Hyperglycaemia-Linked Diabetic Foot Complications and Their Management Using Conventional and Alternative Therapies

  • Prawej Ansari,
  • Samia Akther,
  • Joyeeta T. Khan,
  • Sara S. Islam,
  • Md. Samim R. Masud,
  • Anisur Rahman,
  • Veronique Seidel and
  • Yasser H. A. Abdel-Wahab

19 November 2022

Diabetes mellitus, a major cause of mortality around the globe, can result in several secondary complications, including diabetic foot syndrome, which is brought on by diabetic neuropathy and ischemia. Approximately 15% of diabetic patients suffer fr...

(This article belongs to the Special Issue Diabetic Foot)
  • Review
  • Open Access
185 Citations
13,335 Views
35 Pages

The main aim of this review is to assess the potential use of natural cross-linking agents, such as genipin, citric acid, tannic acid, epigallocatechin gallate, and vanillin in preparing chemically cross-linked hydrogels for the biomedical, pharmaceu...

(This article belongs to the Special Issue Advanced Bio-Hybrid Materials for Drug Delivery Systems - New Trends and Perspectives)
  • Article
  • Open Access
3 Citations
2,528 Views
19 Pages

Seismic Performance and Engineering Application Investigation of a New Alternative Retainer

  • Lei Yan,
  • Guo Li,
  • Xiaoying Gou,
  • Ping Zhang,
  • Xinyong Wang and
  • Yu Jiang

26 August 2022

Focusing on the dilemma that the traditional lateral shear keys are ineffectual in limiting the displacement and repair of small-to-medium spanning highway bridges, this paper briefly describes the necessity of considering fiber-reinforced polymer co...

(This article belongs to the Special Issue Advances in Fiber-Reinforced Polymer Concrete)
  • Article
  • Open Access
17 Citations
4,598 Views
16 Pages

The current state of security and availability of the Internet is far from being commensurate with its importance. The number and strength of DDoS attacks conducted at the network layer have been steadily increasing. However, the single path (SP) rou...

(This article belongs to the Special Issue Advanced Cybersecurity Services Design)
  • Article
  • Open Access
14 Citations
4,455 Views
14 Pages

(1) Background: The Go/NoGo task and color-word Stroop task were used to investigate the effect of applying different frequency bands of neural oscillations to the lDLPFC on inhibitory control modulation. (2) Methods: Participants were randomly categ...

(This article belongs to the Special Issue Neural Basis of Executive Control)
  • Article
  • Open Access
4 Citations
2,643 Views
17 Pages

The Th2 Response and Alternative Activation of Macrophages Triggered by Strongyloides venezuelensis Is Linked to Increased Morbidity and Mortality Due to Cryptococcosis in Mice

  • Ludmila Gouveia-Eufrasio,
  • Gustavo José Cota de Freitas,
  • Marliete Carvalho Costa,
  • Eluzia Castro Peres-Emidio,
  • Paulo Henrique Fonseca Carmo,
  • João Gustavo Mendes Rodrigues,
  • Michelle Carvalho de Rezende,
  • Vanessa Fernandes Rodrigues,
  • Camila Bernardo de Brito and
  • Daniel Assis Santos
  • + 9 authors

26 September 2023

Cryptococcosis is a systemic mycosis that causes pneumonia and meningoencephalitis. Strongyloidiasis is a chronic gastrointestinal infection caused by parasites of the genus Strongyloides. Cryptococcosis and strongyloidiasis affect the lungs and are...

  • Article
  • Open Access
21 Citations
3,557 Views
17 Pages

Polysaccharides of Salsola passerina: Extraction, Structural Characterization and Antioxidant Activity

  • Victoria Golovchenko,
  • Sergey Popov,
  • Vasily Smirnov,
  • Victor Khlopin,
  • Fedor Vityazev,
  • Shinen Naranmandakh,
  • Andrey S. Dmitrenok and
  • Alexander S. Shashkov

29 October 2022

The above-ground part of the Salsola passerine was found to contain ~13% (w/w) of polysaccharides extractable with water and aqueous solutions of ammonium oxalate and sodium carbonate. The fractions extracted with aqueous sodium carbonate solutions h...

(This article belongs to the Collection Feature Papers Collection in Biochemistry)
  • Article
  • Open Access
6 Citations
2,944 Views
19 Pages

25 October 2023

In social sciences, multiple groups, such as countries, are frequently compared regarding a construct that is assessed using a number of items administered in a questionnaire. The corresponding scale is assessed with a unidimensional factor model inv...

(This article belongs to the Section Data Science, Machine Learning and Artificial Intelligence)
  • Article
  • Open Access
1 Citations
2,510 Views
13 Pages

Relocation of Sr48 to Chromosome 2D Using an Alternative Mapping Population and Development of a Closely Linked Marker Using Diverse Molecular Technologies

  • Vallence Nsabiyera,
  • Naeela Qureshi,
  • Jianbo Li,
  • Mandeep Randhawa,
  • Peng Zhang,
  • Kerrie Forrest,
  • Urmil Bansal and
  • Harbans Bariana

10 April 2023

The Ug99-effective stem rust resistance gene Sr48 was mapped to chromosome 2A based on its repulsion linkage with Yr1 in an Arina/Forno recombinant inbred line (RIL) population. Attempts to identify markers closely linked to Sr48 using available geno...

(This article belongs to the Special Issue Functional Genomics and Molecular Breeding of Crops)
  • Feature Paper
  • Article
  • Open Access
25 Citations
3,029 Views
30 Pages

18 November 2021

In this article, the Rasch model is used for assessing a mean difference between two groups for a test of dichotomous items. It is assumed that random differential item functioning (DIF) exists that can bias group differences. The case of balanced DI...

(This article belongs to the Special Issue Symmetry and Asymmetry in Multivariate Statistics and Data Science)
  • Feature Paper
  • Article
  • Open Access
692 Views
21 Pages

Link congestion resulting from routine traffic patterns or malicious link flooding attacks (LFAs) poses a significant challenge in datacenter environments. The growing adoption of software-defined networking (SDN) offers a flexible framework for dyna...

  • Article
  • Open Access
7 Citations
5,482 Views
12 Pages

This paper presents a novel inductive link for wireless power transfer (WPT) system of electric vehicles (EVs). The WPT technology uses an alternating magnetic field to transfer electric power through space. The use of the WPT technology for charging...

  • Review
  • Open Access
8 Citations
6,795 Views
18 Pages

The Detection and Bioinformatic Analysis of Alternative 3′ UTR Isoforms as Potential Cancer Biomarkers

  • Nitika Kandhari,
  • Calvin A. Kraupner-Taylor,
  • Paul F. Harrison,
  • David R. Powell and
  • Traude H. Beilharz

Alternative transcript cleavage and polyadenylation is linked to cancer cell transformation, proliferation and outcome. This has led researchers to develop methods to detect and bioinformatically analyse alternative polyadenylation as potential cance...

(This article belongs to the Section Molecular Oncology)
  • Article
  • Open Access
3 Citations
5,770 Views
11 Pages

Handling in the Production of Wire-Based Linked Micro Parts

  • Philipp Wilhelmi,
  • Christian Schenck and
  • Bernd Kuhfuss

For simplified processing and the enhancement of output rate in multi-stage production, micro parts are handled as linked parts. This contribution discusses handling specific challenges in production based on an exemplary process chain. The examined...

(This article belongs to the Special Issue Micro/Nano Manufacturing)
  • Article
  • Open Access
1 Citations
794 Views
12 Pages

28 March 2025

Linking methods based on item response theory aim to place item parameters from different groups, test forms, or test administrations onto a common scale. Information-weighted Haebara linking has been proposed as an alternative to the widely used sta...

(This article belongs to the Section Information Processes)
  • Article
  • Open Access
32 Citations
6,802 Views
15 Pages

A Near-Infrared Fluorescent Probe Based on a FRET Rhodamine Donor Linked to a Cyanine Acceptor for Sensitive Detection of Intracellular pH Alternations

  • Yibin Zhang,
  • Jianheng Bi,
  • Shuai Xia,
  • Wafa Mazi,
  • Shulin Wan,
  • Logan Mikesell,
  • Rudy L. Luck and
  • Haiying Liu

18 October 2018

A fluorescence resonance energy transfer (FRET)-based near-infrared fluorescent probe (B+) for double-checked sensitive detection of intracellular pH changes has been synthesized by binding a near-infrared rhodamine donor to a near-infrared cyanine a...

(This article belongs to the Special Issue Small Molecule Near Infrared Contrast Agents: Synthesis and Applications)
  • Review
  • Open Access
29 Citations
8,115 Views
22 Pages

Alternative Splicing in Cancer and Immune Cells

  • Antoine Bernard,
  • Romain Boidot and
  • Frédérique Végran

28 March 2022

Splicing is a phenomenon enabling the excision of introns from pre-mRNA to give rise to mature mRNA. All the 20,000 genes of the human genome are concerned by this mechanism. Nevertheless, it is estimated that the proteome is composed of more than 10...

(This article belongs to the Special Issue Alternative and Aberrant Splicing in Cancer: How Can We Fix It?)
  • Article
  • Open Access
15 Citations
4,190 Views
14 Pages

Transcriptomic Analysis of the Pistacia vera (L.) Fruits Enable the Identification of Genes and Hormone-Related Gene Linked to Inflorescence Bud Abscission

  • Jubina Benny,
  • Antonio Giovino,
  • Francesco Paolo Marra,
  • Bipin Balan,
  • Federico Martinelli,
  • Tiziano Caruso and
  • Annalisa Marchese

27 December 2021

Pistacia vera (L.) is an alternate bearing species. The tree produces axillary inflorescence buds every year. Still, they abscise in “ON” overloaded shoots, causing a limited production in the following “OFF” year, causing a s...

(This article belongs to the Section Plant Genetics and Genomics)
  • Article
  • Open Access
10 Citations
5,666 Views
27 Pages

7 April 2022

Due to the low demand for conventional annuities, alternative retirement products are sought. Quite recently, tontines have been frequently brought up as a promising option in this respect. Inspired by unit-linked life insurance and retirement produc...

(This article belongs to the Special Issue Actuarial Mathematics and Risk Management)
  • Article
  • Open Access
51 Citations
7,602 Views
10 Pages

Performance Analysis of Hard-Switching Based Hybrid FSO/RF System over Turbulence Channels

  • Hira Khalid,
  • Sajid Sheikh Muhammad,
  • Hector E. Nistazakis and
  • George S. Tombras

The hybrid system of free space optic (FSO) and radio frequency (RF) has come forth as alternative good solution for increasing demand for high data rates in wireless communication networks. In this paper, wireless networks with hard-switching betwee...

(This article belongs to the Special Issue Optical Wireless Communication Systems)
  • Feature Paper
  • Article
  • Open Access
10 Citations
1,438 Views
14 Pages

26 December 2024

Mean-geometric mean (MGM) linking is a widely used method for linking two groups within the two-parameter logistic (2PL) item response model. However, the presence of differential item functioning (DIF) can lead to biased parameter estimates using th...

(This article belongs to the Special Issue Multivariate Statistical Analysis and Application)
  • Article
  • Open Access
24 Citations
3,685 Views
12 Pages

Acid System and Stimulation Efficiency of Multistage Acid Fracturing in Porous Carbonate Reservoirs

  • Dawei Zhu,
  • Yunjin Wang,
  • Mingyue Cui,
  • Fujian Zhou,
  • Yaocong Wang,
  • Chong Liang,
  • Honglan Zou and
  • Fei Yao

17 September 2022

With little to no natural fracture development and the high calcite content in porous carbonate reservoirs, for multistage acid fracturing, different fluids are used to form a viscous fingering in the fracture, thus enhancing the degree of nonuniform...

(This article belongs to the Special Issue Recent Advances in Reservoir Stimulation and EOR Technology in Unconventional Reservoirs)
  • Article
  • Open Access
5 Citations
2,574 Views
16 Pages

Evaluation of Various Alternative Economical and High Throughput SARS-CoV-2 Testing Methods within Resource-Limited Settings

  • Zamathombeni Duma,
  • Veron Ramsuran,
  • Anil A. Chuturgoon,
  • Vinodh A. Edward,
  • Pragalathan Naidoo and
  • Zilungile L. Mkhize-Kwitshana

18 November 2022

The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) outbreak posed a challenge for diagnostic laboratories worldwide, with low-middle income countries (LMICs) being the most affected. The polymerase chain reaction (PCR) is the gold stand...

(This article belongs to the Section Molecular Informatics)
  • Article
  • Open Access
7 Citations
4,325 Views
22 Pages

ISA 100.11a Networked Control System Based on Link Stability

  • Heitor Florencio,
  • Adrião Dória Neto and
  • Daniel Martins

21 September 2020

Wireless networked control systems (WNCSs) must ensure that control systems are stable, robust and capable of minimizing the effects of disturbances. Due to the need for a stable and secure WNCS, critical wireless network variables must be taken into...

(This article belongs to the Special Issue Industrial Wireless Sensor Networks: Protocols and Applications)
  • Review
  • Open Access
104 Citations
12,122 Views
22 Pages

Tau Isoforms: Gaining Insight into MAPT Alternative Splicing

  • Andrea Corsi,
  • Cristina Bombieri,
  • Maria Teresa Valenti and
  • Maria Grazia Romanelli

6 December 2022

Tau microtubule-associated proteins, encoded by the MAPT gene, are mainly expressed in neurons participating in axonal transport and synaptic plasticity. Six major isoforms differentially expressed during cell development and differentiation are tran...

(This article belongs to the Special Issue Mechanism and Regulation of Pre-mRNA Splicing 2.0)
  • Article
  • Open Access
1,416 Views
17 Pages

1 April 2026

A growing body of research characterizes contemporary global neoliberal hegemony through the lens of racial capitalism—a framework that traces the connections between colonial exploitation, slavery, and the foundations of economic growth, linki...

(This article belongs to the Special Issue Social Conflict, Migration and Forced Labour: Contemporary and Emerging Issues)
  • Article
  • Open Access
1,805 Views
31 Pages

Hybrid Methods for Selecting Precast Concrete Suppliers Based on Factory Capacity

  • Mohammed I. Aldokhi,
  • Khalid S. Al-Gahtani,
  • Naif M. Alsanabani and
  • Saad I. Aljadhai

18 July 2025

Supplier selection is one of the critical processes that entail multiple complex deliberations. The selection of an appropriate alternative supplier is a highly intricate process, primarily due to there being multiple criteria which are exceptionally...

  • Article
  • Open Access
25 Citations
6,355 Views
11 Pages

18 September 2019

From 2021 onwards, surgical castration of male piglets without pain relief will be banned in Germany. In Europe, stakeholders have committed themselves to end piglet castration from 2018 onwards. Alternatives to surgical castration are pork productio...

  • Article
  • Open Access
18 Citations
4,587 Views
21 Pages

14 October 2018

Although the consideration of alternatives is seen as a core element of impact assessments (IA) such as environmental impact assessments (EIAs) and strategic environmental assessments (SEAs), there are few scientific papers that have addressed this t...

(This article belongs to the Section Environmental Sustainability and Applications)

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