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  • Article
  • Open Access
18 Citations
8,662 Views
12 Pages

High-Performance Thin-Layer Chromatography for Rutin, Chlorogenic Acid, Caffeic Acid, Ursolic Acid, and Stigmasterol Analysis in Periploca aphylla Extracts

  • Raha Orfali,
  • Shagufta Perveen,
  • Hanan Y. Aati,
  • Perwez Alam,
  • Omar M. Noman,
  • Javier Palacios,
  • Bayan Salem S. Al-Kurbi,
  • Areej M. Al-Taweel,
  • Afsar Khan and
  • Shabana Iqrar Khan
  • + 1 author

Periploca aphylla (PA), an interesting Saudi medicinal plant, is used in folk medicine to treat urticaria, cerebral fever, tumors, and swelling. To prove its use in folk medicine, two different extracts from the aerial parts of the plant: chloroform...

  • Article
  • Open Access
3 Citations
3,176 Views
14 Pages

The rapid, highly-sensitive and ecologically greener reversed-phase (RP)/normal-phase (NP) high-performance thin-layer chromatography (HPTLC) densitometric technique has been developed and validated for the determination of trans-resveratrol (TRV). T...

(This article belongs to the Section Analysis of Food and Beverages)
  • Article
  • Open Access
21 Citations
10,018 Views
14 Pages

The retention behavior of a wide variety of stationary phases was compared in supercritical fluid chromatography (SFC) and normal-phase high-performance liquid chromatography (NP-HPLC). We also attempted to elucidate the retention behavior in SFC by...

(This article belongs to the Special Issue Supercritical Fluids and Green Chemistry)
  • Article
  • Open Access
44 Citations
5,362 Views
14 Pages

29 June 2019

Breast cancer is considered the most common and deadly cancer among women worldwide. Nanomedicine has become extremely attractive in the field of cancer treatment. Due to the high surface to volume ratio and other unique properties, nanomaterials can...

(This article belongs to the Special Issue Anticancer Agents: Design, Synthesis and Evaluation)
  • Article
  • Open Access
4 Citations
5,620 Views
14 Pages

Changes in the Metabolite Profile during Micropropagation of Normal and Somaclonal Variants of Banana Musa AAA cv. Williams

  • Fredy P. Carrera,
  • Carlos Noceda,
  • María G. Maridueña-Zavala,
  • José A. García,
  • Omar Ruiz-Barzola and
  • Juan M. Cevallos-Cevallos

Micropropagation techniques allow the mass production of banana plants but can cause somaclonal variations such as dwarfism. Changes in the metabolite profile during micropropagation of normal (NP) and dwarf (DP) banana plants have not been described...

(This article belongs to the Section Propagation and Seeds)
  • Article
  • Open Access
17 Citations
4,105 Views
15 Pages

28 July 2021

The greenness evaluation of literature analytical methods for pterostilbene (PT) analysis was not performed. Accordingly, the rapid, sensitive, and green/sustainable reversed-phase high-performance thin-layer chromatography (RP-HPTLC) method was deve...

(This article belongs to the Special Issue Pharmaceutical and Biomedical Analysis)
  • Article
  • Open Access
5 Citations
5,891 Views
15 Pages

3 June 2024

TLC (thin-layer chromatography) and HPTLC (high-performance thin-layer chromatography) in normal (NP) and reversed (RP) phase systems were combined with densitometry to analyze caffeine, propyphenazone, and paracetamol. This work aims to check whethe...

(This article belongs to the Special Issue Applications of Chromatographic Separation Techniques in Food and Chemistry—Second Edition)
  • Article
  • Open Access
2 Citations
3,467 Views
19 Pages

13 June 2025

Background: Plastic is one of the most versatile and widely used materials, but the environmental accumulation of nanoplastics (NPs) poses a risk to human health. Preclinical studies have verified that the liver is one of the main organs susceptible...

(This article belongs to the Section Nutrition and Public Health)
  • Article
  • Open Access
1 Citations
2,476 Views
15 Pages

A nifedipine (NP) dry emulsion was fabricated by the adsorption of medium internal-phase emulsions (MIPEs). Simple homogenizers were first used to mix conventional liquid MIPEs, and then a microfluidizer was used to reduce the resulting emulsions&rsq...

(This article belongs to the Section Drug Delivery and Controlled Release)
  • Article
  • Open Access
1 Citations
1,372 Views
14 Pages

22 September 2025

Nonylphenols (NPs), widely used as emulsifiers in petroleum production and refining, are compounds of environmental concern, with endocrine-disrupting effects. They can be released during oil extraction and processing, carried into petroleum products...

(This article belongs to the Special Issue Advancing Sustainability in the Upstream Oil and Gas Industry: Waste Valorization, Emission Control, and Environmental Management)
  • Article
  • Open Access
25 Citations
4,716 Views
14 Pages

Determination of Delafloxacin in Pharmaceutical Formulations Using a Green RP-HPTLC and NP-HPTLC Methods: A Comparative Study

  • Prawez Alam,
  • Essam Ezzeldin,
  • Muzaffar Iqbal,
  • Gamal A.E. Mostafa,
  • Md. Khalid Anwer,
  • Mohammed H. Alqarni,
  • Ahmed I. Foudah and
  • Faiyaz Shakeel

In this work; delafloxacin (DLFX) was determined using a validated green RP-HPTLC and NP-HPTLC methods in commercial tablets and in-house developed solid lipid nanoparticles (SLNs). RP-HPTLC determination of DLFX was performed using “RP-18 sili...

(This article belongs to the Special Issue Challenges in Antibiotics Analysis)
  • Article
  • Open Access
10 Citations
3,639 Views
14 Pages

Melting and Recrystallization of Copper Nanoparticles Prepared by Microwave-Assisted Reduction in the Presence of Triethylenetetramine

  • Li-Cheng Jheng,
  • Yen-Zen Wang,
  • Wen-Yao Huang,
  • Ko-Shan Ho,
  • Cheng-Hsien Tsai,
  • Ching-Tang Huang and
  • Huang-Shian Tsai

26 March 2020

The small sized copper nanoparticles (Cu-NPs), prepared in the presence of triethylene tetramine (TETA) and assisted with microwave irradiation, have an extremely low melting temperature. Melting of the small sizezd Cu-NPs can be triggered by the hea...

(This article belongs to the Special Issue Properties of Amorphous Materials and Nanomaterials)
  • Article
  • Open Access
9 Citations
5,499 Views
14 Pages

In Silico Plasma Protein Binding Studies of Selected Group of Drugs Using TLC and HPLC Retention Data

  • Karolina Wanat,
  • Grażyna Żydek,
  • Adam Hekner and
  • Elżbieta Brzezińska

28 February 2021

Plasma protein binding is an important determinant of the pharmacokinetic properties of chemical compounds in living organisms. The aim of the present study was to determine the index of protein binding affinity based on chromatographic experiments....

(This article belongs to the Special Issue Selected Papers from the 6th International Electronic Conference on Medicinal Chemistry (ECMC2020))
  • Article
  • Open Access
30 Citations
6,645 Views
21 Pages

A Comparative and Critical Analysis for In Vitro Cytotoxic Evaluation of Magneto-Crystalline Zinc Ferrite Nanoparticles Using MTT, Crystal Violet, LDH, and Apoptosis Assay

  • Juan Luis de la Fuente-Jiménez,
  • César Iván Rodríguez-Rivas,
  • Irma Beatriz Mitre-Aguilar,
  • Andrea Torres-Copado,
  • Eric Alejandro García-López,
  • José Herrera-Celis,
  • María Goretti Arvizu-Espinosa,
  • Marco Antonio Garza-Navarro,
  • Luis Gerardo Arriaga and
  • Goldie Oza
  • + 4 authors

16 August 2023

Zinc ferrite nanoparticles (ZFO NPs) are a promising magneto-crystalline platform for nanomedicine-based cancer theranostics. ZFO NPs synthesized using co-precipitation method are characterized using different techniques. UV-visible spectroscopy exhi...

(This article belongs to the Special Issue New Perspectives of Colloids for Biological Applications)
  • Article
  • Open Access
3 Citations
1,265 Views
39 Pages

A Composite Based on L-Polylactide with Cu or CuO Nanoparticles: Physical Properties and Biological Activity

  • Dmitriy A. Serov,
  • Fatikh M. Yanbaev,
  • Dmitriy E. Burmistrov,
  • Ilya V. Baimler,
  • Sergei O. Liubimovskii,
  • Liudmila Y. Kozlova,
  • Ivan A. Popov,
  • Ann V. Gritsaeva,
  • Polina A. Fomina and
  • Sergey V. Gudkov
  • + 5 authors

17 April 2026

The development of biodegradable, biocompatible materials with inherent antibacterial properties, suitable for 3D printing, is a key challenge in modern materials science. Composites based on PLA and copper nanoparticles (NPs) are promising candidate...

(This article belongs to the Special Issue Polymer Nanocomposites and Nanoparticles: Preparation and Applications)
  • Article
  • Open Access
18 Citations
5,065 Views
13 Pages

A Comparative Study of the Lipophilicity of Metformin and Phenformin

  • Małgorzata Dołowy,
  • Josef Jampilek and
  • Katarzyna Bober-Majnusz

31 October 2021

The results presented in this paper confirm the beneficial role of an easy-to-use and low-cost thin-layer chromatography (TLC) technique for describing the retention behavior and the experimental lipophilicity parameter of two biguanide derivatives,...

(This article belongs to the Special Issue Design, Synthesis, and Analysis of Potential Drugs)
  • Article
  • Open Access
33 Citations
3,663 Views
25 Pages

20 July 2023

The main hypothesis of the present research is investigating the efficacy of titanium oxide nanoparticles (TiO2-NPs) to prevent the growth of fungal strains when applied on leather under an experimental study. Therefore, fifteen fungal strains were i...

  • Article
  • Open Access
65 Citations
10,751 Views
17 Pages

Novel Gold Nanoparticles Reduced by Sargassum glaucescens: Preparation, Characterization and Anticancer Activity

  • Zahra Ajdari,
  • Heshu Rahman,
  • Kamyar Shameli,
  • Rasedee Abdullah,
  • Maaruf Abd Ghani,
  • Swee Yeap,
  • Sahar Abbasiliasi,
  • Daniel Ajdari and
  • Arbakariya Ariff

The current study investigated the anticancer properties of gold nanoparticles (SG-stabilized AuNPs) synthesized using water extracts of the brown seaweed Sargassum glaucescens (SG). SG-stabilized AuNPs were characterized by ultraviolet-visible spect...

(This article belongs to the Special Issue Pharmaceutical Nanotechnology: Novel Approaches)
  • Article
  • Open Access
29 Citations
4,606 Views
17 Pages

Effects of Protein Restriction and Subsequent Realimentation on Body Composition, Gut Microbiota and Metabolite Profiles in Weaned Piglets

  • Lei Hou,
  • Li Wang,
  • Yueqin Qiu,
  • YunXia Xiong,
  • Hao Xiao,
  • Hongbo Yi,
  • Xiaolu Wen,
  • Zeling Lin,
  • Zhikang Wang and
  • Zongyong Jiang
  • + 1 author

4 March 2021

The objective of this study was to evaluate the effects of protein restriction and subsequent protein realimentation on the body composition, gut microbiota and metabolite profiles of piglets. Fifty weaned piglets were randomly assigned to two treatm...

(This article belongs to the Collection The Weaned Pig: Nutrition and Management)
  • Article
  • Open Access
29 Citations
4,227 Views
14 Pages

Polianthes tuberosa-Mediated Silver Nanoparticles from Flower Extract and Assessment of Their Antibacterial and Anticancer Potential: An In Vitro Approach

  • Mousa A. Alghuthaymi,
  • Sunita Patil,
  • Chandrasekaran Rajkuberan,
  • Muthukumar Krishnan,
  • Ushani Krishnan and
  • Kamel A. Abd-Elsalam

10 March 2023

Plant-mediated metallic nanoparticles have beenreported for a diversified range of applications in biological sciences. In the present study, we propose the Polianthes tuberosa flower as a reducing and stabilizing agent for the synthesis of silver na...

  • Article
  • Open Access
9 Citations
5,212 Views
10 Pages

16 November 2019

The present research is focused on the in-depth qualitative analysis of three types of lime essential oil (EO), viz., Key (A and B) and Persian, using the off-line combination of normal phase high performance liquid chromatography (NP-HPLC) and compr...

(This article belongs to the Special Issue Rapid Detection Methods for Food Fraud and Food Contaminants)
  • Article
  • Open Access
17 Citations
3,138 Views
19 Pages

7 November 2020

This paper investigates the cooling performance of nanofluid (NF) mixed convection in a porous I-shaped electronic chip with an internal triangular hot block using Buongiorno’s two-phase model. This type of cavity and hot block geometry has not...

(This article belongs to the Special Issue Applications of Nanofluids)
  • Review
  • Open Access
20 Citations
14,195 Views
37 Pages

4 October 2016

To obtain enantiopure compounds, the so-called chiral high performance liquid chromatography (HPLC) method, i.e., HPLC using a chiral stationary phase, is very useful, as reviewed in the present Special Issue. On the other hand, normal HPLC (on silic...

(This article belongs to the Special Issue Chromatographic Separation of Enantiomers: Commemorative Issue in Honor of Professor Stig Allenmark on the Occasion of His 80th Birthday)
  • Article
  • Open Access
3 Citations
3,444 Views
20 Pages

30 August 2023

The present work proposes the optimization of the co-digestion of vinasse, filter cake, and deacetylation liquor in a continuous reactor by adding iron(III) oxide (Fe3O4) nanoparticles (NPs), comparing the results with a previous reactor operation wi...

(This article belongs to the Collection Feature Papers for Applied Nano)
  • Article
  • Open Access
10 Citations
3,304 Views
18 Pages

Graphene Oxide Nanoparticles for Photothermal Treatment of Hepatocellular Carcinoma Using Low-Intensity Femtosecond Laser Irradiation

  • Charilaos Xenodochidis,
  • Kamelia Hristova-Panusheva,
  • Trayana Kamenska,
  • Poornima Budime Santhosh,
  • Todor Petrov,
  • Lyubomir Stoychev,
  • Julia Genova and
  • Natalia Krasteva

28 November 2024

Graphene oxide-mediated photothermal therapy using femtosecond lasers has recently shown promise in treating hepatocellular carcinoma. However, significant work remains to optimize irradiation parameters for specific nanoparticle types and cancer cel...

(This article belongs to the Special Issue New Nanomaterials for Diagnostic and Drug Delivery)
  • Article
  • Open Access
102 Citations
7,281 Views
16 Pages

ZnO Nanoparticles Induced Caspase-Dependent Apoptosis in Gingival Squamous Cell Carcinoma through Mitochondrial Dysfunction and p70S6K Signaling Pathway

  • Shih-Wei Wang,
  • Chien-Hsing Lee,
  • Ming-Shen Lin,
  • Chih-Wen Chi,
  • Yu-Jen Chen,
  • Guo-Shou Wang,
  • Kuang-Wen Liao,
  • Li-Pin Chiu,
  • Shu-Hui Wu and
  • Yung-Shuen Shen
  • + 2 authors

26 February 2020

Zinc oxide nanoparticles (ZnO-NPs) are increasingly used in sunscreens, food additives, pigments, rubber manufacture, and electronic materials. Several studies have shown that ZnO-NPs inhibit cell growth and induce apoptosis by the production of oxid...

(This article belongs to the Special Issue Bio-Engineering and Nano-Medicine)
  • Review
  • Open Access
15 Citations
3,331 Views
15 Pages

Interleukin 8 Molecular Interplay in Allergic Rhinitis and Chronic Rhinosinusitis with Nasal Polyps: A Scoping Review

  • Romica Cergan,
  • Ovidiu Berghi,
  • Mihai Dumitru,
  • Daniela Vrinceanu,
  • Felicia Manole,
  • Gabriela Cornelia Musat,
  • Alina Lavinia Antoaneta Oancea and
  • Crenguta Serboiu

15 March 2025

The present scoping review underlines the molecular interplay between allergic rhinitis (AR), chronic rhinosinusitis with nasal polyps (CRSwNP), and interleukin-8 (IL-8). A query of PubMed database resulted in the inclusion of 34 articles in the fina...

(This article belongs to the Section Physiology and Pathology)
  • Article
  • Open Access
8 Citations
3,657 Views
16 Pages

The Impact of Producing Type and Dietary Crude Protein on Animal Performances and Microbiota Together with Greenhouse Gases Emissions in Growing Pigs

  • Ahmad Reza Seradj,
  • Joaquim Balcells,
  • Laura Sarri,
  • Lorenzo José Fraile and
  • Gabriel de la Fuente Oliver

25 September 2020

In order to reduce dietary nitrogen and achieve an efficient protein deposition as well as decrease N wastage, we challenged the nutrient utilization efficiency of two different producing types in front of a dietary crude protein (CP) restriction and...

(This article belongs to the Special Issue Feed Intervention in Livestock Nutrition: Effects on Gut Microbial Ecology)
  • Article
  • Open Access
3 Citations
3,810 Views
11 Pages

Due to a trend to higher sustainability, biodiesel is often mixed into petrodiesel. The analysis of these blends on a molecular level is not trivial, since huge differences in concentrations and polarity of the analytes require a large dynamic range...

(This article belongs to the Section Separation Science in Energies)
  • Article
  • Open Access
3 Citations
3,518 Views
12 Pages

Clock/Sleep-Dependent Learning and Memory in Male 3xTg-AD Mice at Advanced Disease Stages and Extrinsic Effects of Huprine X and the Novel Multitarget Agent AVCRI104P3

  • Lydia Giménez-Llort,
  • Mikel Santana-Santana,
  • Míriam Ratia,
  • Belén Pérez,
  • Pelayo Camps,
  • Diego Muñoz-Torrero,
  • Albert Badia and
  • Maria Victòria Clos

A new hypothesis highlights sleep-dependent learning/memory consolidation and regards the sleep-wake cycle as a modulator of β-amyloid and tau Alzheimer’s disease (AD) pathologies. Sundowning behavior is a common neuropsychiatric symptom (NPS) associ...

(This article belongs to the Special Issue Sleep in Healthy and Pathological Aging)
  • Article
  • Open Access
31 Citations
4,646 Views
13 Pages

25 October 2020

Nanofluids have extensive applications in hydrodynamic journal bearings used in heavy industry machinery. Inorganic fullerene-like tungsten disulfide nanoparticles (IF-WS2 NPs) are the most common additive for lubrication purpose due to their excelle...

(This article belongs to the Special Issue Nanofluids and Nanofluidics)
  • Article
  • Open Access
16 Citations
4,527 Views
13 Pages

The tunneling of electrons and holes in quantum structures plays a crucial role in studying the transport properties of materials and the related devices. 8-Pmmn borophene is a new two-dimensional Dirac material that hosts tilted Dirac cone and chira...

(This article belongs to the Special Issue Graphene for Electronics)
  • Article
  • Open Access
28 Citations
3,547 Views
18 Pages

Effect of Selenium Nanoparticles and Mannan Oligosaccharide Supplementation on Growth Performance, Stress Indicators, and Intestinal Microarchitecture of Broilers Reared under High Stocking Density

  • Hafiz Faseeh ur Rehman,
  • Hafsa Zaneb,
  • Saima Masood,
  • Muhammad Shahbaz Yousaf,
  • Khizar Hayat,
  • Khalid Abdul Majeed,
  • Muhammad Zeeshan,
  • Saima Ashraf,
  • Imad Khan and
  • Habib Rehman
  • + 1 author

24 October 2022

The current study investigated the potential of selenium nanoparticles (SeNPs) and mannan-oligosaccharide (MOS) supplementation in ameliorating high stocking density (HSD) stress in broilers. A total of 392 day-old male chicks were divided into seven...

(This article belongs to the Special Issue Research Progress in Poultry Production, Intestinal Health, and Product Quality)
  • Article
  • Open Access
4 Citations
2,867 Views
10 Pages

Intentionally Lengthening Nonparetic Step Length Inhibits the Paretic-Side Swing-Phase Ankle Motion More than Knee Motion

  • Yuichi Tsushima,
  • Kazuki Fujita,
  • Koji Hayashi,
  • Hiroichi Miaki and
  • Katsuhiro Hayashi

Gait training to intentionally lengthen the nonparetic step length can increase the propulsive force of the paretic leg but may also induce overactivity of the knee extensor muscles that might limit knee flexion during the swing phase. Herein, we inv...

(This article belongs to the Section Gait and Posture Biomechanics)
  • Article
  • Open Access
30 Citations
5,231 Views
13 Pages

Biosynthesis, Characterization, and Augmented Anticancer Activity of ZrO2 Doped ZnO/rGO Nanocomposite

  • Maqusood Ahamed,
  • Rashid Lateef,
  • M. A. Majeed Khan,
  • Pavan Rajanahalli and
  • Mohd Javed Akhtar

Fabrication of ZnO nanoparticles (NPs) via green process has received enormous attention for its application in biomedicine. Here, a simple and cost-effective green route is reported for the synthesis of ZrO2-doped ZnO/reduced graphene oxide nanocomp...

(This article belongs to the Section Antibacterial Biomaterials)
  • Article
  • Open Access
8 Citations
5,991 Views
12 Pages

Development and Validation of a Simple Analytical Method to Quantify Tocopherol Isoforms in Food Matrices by HPLC–UV–Vis

  • María Fernanda Arias-Santé,
  • Sussi López-Puebla,
  • Adriano Costa de Camargo,
  • José Luis Guil-Guerrero and
  • Miguel Ángel Rincón-Cervera

27 September 2024

This study developed, validated, and tested a simple method for tocopherol analysis on five different food matrices (sunflower oil, mackerel fillets, almonds, spinach, and avocado pulp). Tocopherol extraction from foods was carried out by the Folch m...

(This article belongs to the Special Issue New Insights into Bioactive Compounds)
  • Article
  • Open Access
2 Citations
1,338 Views
20 Pages

Macrophage apoptosis, along with inflammation in the interface membrane, has been demonstrated to be significant in the pathogenesis and development of particle-induced periprosthetic osteolysis and aseptic loosening. Additionally, the apoptosis of m...

(This article belongs to the Section Biomedical Engineering and Biomaterials)
  • Article
  • Open Access
1 Citations
1,803 Views
24 Pages

A Comprehensive Physicochemical Analysis Focusing on the Characterization and Stability of Valsartan Silver Nano-Conjugates

  • Abdul Qadir,
  • Khwaja Suleman Hasan,
  • Khair Bux,
  • Khwaja Ali Hasan,
  • Aamir Jalil,
  • Asad Khan Tanoli,
  • Khwaja Akbar Hasan,
  • Shahida Naz,
  • Muhammad Kashif and
  • Shama Qaiser
  • + 4 authors

Valsartan (Val)—a lipophilic non-peptide angiotensin II type 1 receptor antagonist—is highly effective against hypertension and displaying limited solubility in water (3.08 μg/mL), thereby resulting in low oral bioavailability (23%). T...

(This article belongs to the Special Issue 25th Anniversary of IJMS: Updates and Advances in Molecular Nanoscience)
  • Article
  • Open Access
173 Views
28 Pages

Green Synthesis of Silver Nanoparticles Using Artemisia absinthium and Ziziphus vulgaris Extracts: Comparative Evaluation of Antibacterial, Anti-Inflammatory, Wound-Healing and Anticancer Activities

  • Mohammed Gamal,
  • Asma B. Omer,
  • Asmaa Saleh,
  • Roula Bayram,
  • Ibrahim A. Naguib,
  • Mohamed Ahmed Elsayed,
  • Safa Mousa and
  • Hamad M. Adress Hasan

14 October 2026

Background: Plant-mediated synthesis of silver nanoparticles (AgNPs) has emerged as a sustainable alternative to conventional chemical methods, offering environmentally friendly routes for producing nanomaterials with biomedical potential. This study...

(This article belongs to the Section Pharmaceutical Technology)
  • Article
  • Open Access
33 Citations
5,625 Views
27 Pages

6 September 2022

Glioblastoma multiforme (GBM) is considered to be one of the most serious version of primary malignant tumors. Temozolomide (TMZ), an anti-cancer drug, is the most common chemotherapeutic agent used for patients suffering from GBM. However, due to it...

(This article belongs to the Section Medicinal Chemistry)
  • Article
  • Open Access
21 Citations
4,263 Views
20 Pages

Potentially Bioactive Fungus Mediated Silver Nanoparticles

  • Abu Baker,
  • Sana Iram,
  • Asad Syed,
  • Abdallah M. Elgorban,
  • Abdullah Msaad Al-Falih,
  • Ali H. Bahkali,
  • Mohd Sajid Khan and
  • Jihoe Kim

28 November 2021

Fungal metabolites, proteins, and enzymes have been rich sources of therapeutics so far. Therefore, in this study, the hypha extract of a newly identified noble fungus (Alternaria sp. with NCBI Accession number: MT982648) was used to synthesize silve...

  • Review
  • Open Access
51 Citations
10,638 Views
29 Pages

Comprehensive Review on Chiral Stationary Phases in Single-Column Simultaneous Chiral–Achiral HPLC Separation Methods

  • Lajos Attila Papp,
  • Zoltán István Szabó,
  • Gabriel Hancu,
  • Lénárd Farczádi and
  • Eleonora Mircia

18 March 2024

This comprehensive review explores the utilization of chiral stationary phases (CSPs) in the context of single-column simultaneous chiral–achiral high-performance liquid chromatography (HPLC) separation methods. While CSPs have traditionally be...

(This article belongs to the Section Analytical Chemistry)
  • Article
  • Open Access
2 Citations
2,441 Views
13 Pages

3 May 2022

As a non-deterministic polynomial hard (NP-hard) problem, the shortest common supersequence (SCS) problem is normally solved by heuristic or metaheuristic algorithms. One type of metaheuristic algorithms that has relatively good performance for solvi...

  • Article
  • Open Access
832 Views
49 Pages

Green-Synthesized Curcuma longa-Derived Silver Nanoparticles for Oral Biomaterial Applications: Physicochemical Characterization, Antibacterial Activity, Preliminary Cytocompatibility and In Ovo Biocompatibility Screening

  • Mhd Kher Alsaeyd Ahmad,
  • Doina Chioran,
  • Dana-Emanuela Pitic (Coţ),
  • Elena-Alina Moacă,
  • Diana Haj Ali,
  • Iasmina-Alexandra Predescu,
  • Alina Hegheş,
  • Cristina-Ioana Talpoş-Niculescu,
  • Ramona-Amina Popovici and
  • Mirela Voicu
  • + 4 authors

Background/Objectives: Plant-mediated silver nanoparticles (AgNPs) are promising components for oral biomaterials because of their antimicrobial potential; however, their biological behavior depends strongly on the phytochemical matrix, physicochemic...

(This article belongs to the Special Issue Smart Biomaterials for Oral Tissue Regeneration)
  • Article
  • Open Access
6 Citations
3,309 Views
31 Pages

10 February 2025

Cloud computing, a superset of heterogeneous distributed computing, allows sharing of geographically dispersed resources across multiple organizations on a rental basis using virtualization as per demand. In cloud computing, workflow allocation to ac...

(This article belongs to the Section Algorithms for Multidisciplinary Applications)
  • Article
  • Open Access
14 Citations
2,140 Views
19 Pages

14 December 2024

In the present work, we achieved the fabrication of MgO-Fe2O3/γ-Al2O3 NCs using a deposition–coprecipitation process. XRD, TEM, and SEM with EDX, XPS, FTIR, and PL spectroscopy were applied to examine the physicochemical properties of the...

  • Article
  • Open Access
9 Citations
3,250 Views
17 Pages

Enantiomeric Separation and Molecular Modelling of Bioactive 4-Aryl-3,4-dihydropyrimidin-2(1H)-one Ester Derivatives on Teicoplanin-Based Chiral Stationary Phase

  • Isabella Bolognino,
  • Antonio Carrieri,
  • Rosa Purgatorio,
  • Marco Catto,
  • Rocco Caliandro,
  • Benedetta Carrozzini,
  • Benny Danilo Belviso,
  • Maria Majellaro,
  • Eddy Sotelo and
  • Cosimo Damiano Altomare
  • + 1 author

The enantiomeric separation of 15 racemic 4-aryl-3,4-dihydropyrimidin-2(1H)-one (DHP) alkoxycarbonyl esters, some of which proved to be highly active as A2B adenosine receptor antagonists, was carried out by HPLC on ChirobioticTM TAG, a chiral statio...

(This article belongs to the Special Issue Separation, Extraction and Purification of Natural Products from Plants)
  • Article
  • Open Access
2,312 Views
37 Pages

The consumption of grape seed extracts is known for its contribution to animal and human health and is associated with its relevant procyanidin content. However, there is a little scientific unanimity whether these properties are due to the procyanid...

(This article belongs to the Section Membrane Applications for Other Areas)
  • Article
  • Open Access
4 Citations
2,555 Views
18 Pages

Interaction of Manganese-Doped Copper Oxide Nano-Platelets with Cells: Biocompatibility and Anticancer Activity Assessment

  • Ioan-Ovidiu Pană,
  • Alexandra Ciorîță,
  • Sanda Boca,
  • Simona Guțoiu,
  • Irina Kacso,
  • Maria Olimpia Miclăuș,
  • Oana Grad,
  • Ana Maria Raluca Gherman,
  • Cristian Leostean and
  • Maria Suciu

Understanding cellular interaction with nanomaterials represents a subject of great interest for the validation of new diagnostic and therapeutic tools. A full characterization of a designed product includes the evaluation of its impact on specific b...

  • Article
  • Open Access
3 Citations
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19 Pages

25 May 2025

As a typical desert oasis ecosystem in the arid region of Northwest China, the Ejina Delta plays a crucial role in regional ecological security through its vegetation dynamics and landscape pattern changes. Based on Landsat remote sensing images (199...

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