In the past decade, there has been an increasing trend of digitalizing rock engineering processes. However, this process has not been accompanied by a critical analysis of the very same empirical methods that many complex numerical and digital method...
It has been demonstrated that inhibiting Notch signaling through γ-secretase inhibitor (GSI) treatment increases myogenesis, AKT/mTOR signaling, and muscle protein synthesis (MPS) in C2C12 myotubes. The purpose of this study was to determine if GSI-m...
Geotechnical seismic isolation (GSI) consists of an innovative technique to mitigate the effects of earthquakes based on interposing a superficial soil layer to filter the seismic energy from the soil to the structure. This approach is particularly a...
This paper provides research that shows that the scale and quantification of the degree of fracturing in a rock mass should and can be considered when estimating geological strength index (GSI) ratings for rock mass strength and deformability estimat...
The role of Notch signaling is widely studied in skeletal muscle regeneration but little is known about its influences on muscle protein synthesis (MPS). The purpose of this study was to investigate whether Notch signaling is involved in the regulati...
Excavation is a common requirement in engineering construction within rock masses. While excavation volumes are generally limited in road slope projects, they may become substantial in large-scale operations such as deep open pit mines. The interacti...
A comprehensive understanding of geological, structural geological, hydrogeological and geotechnical features of the host rock are essential for the design and performance evaluation of surface and underground excavations. The Hungarian National Radi...
The MicroWave Humidity Sounder 2 (MWHS-2) onboard the FY-3C satellite provides an extra important data source for atmospheric water vapor monitoring besides the Microwave Humidity Sounder (MHS) and the Advanced Technology Microwave Sounder (ATMS). Th...
Global Navigation Satellite System (GNSS) radio occultation (RO) provides plentiful sounding profiles over regions lacking conventional observations. The Gridpoint Statistical Interpolation (GSI) hybrid system for assimilating RO data is integrated i...
The feasibility of a hurricane initialization framework based on the Gridpoint Statistical Interpolation (GSI)-based four-dimensional ensemble-variational (GSI-4DEnVar) hybrid data assimilation system for the Hurricane Weather Research and Forecastin...
The National Oceanic and Atmospheric Administration’s (NOAA) cloud-permitting high-resolution operational Hurricane Weather and Research Forecasting (HWRF) model includes the sophisticated hybrid grid-point statistical interpolation (GSI) and E...
Over the past few decades, there has been a notable surge in interest in green stormwater infrastructure (GSI). This trend is a result of the need to effectively address issues related to runoff, pollution, and the adverse effects of urbanization and...
Municipalities across the United States are prioritizing green stormwater infrastructure (GSI) projects due to their potential to concurrently optimize the social, economic, and environmental benefits of the “triple bottom line”. While pl...
Many studies focus on brittle–ductile transition stress in intact rocks; however, in real life, we deal with rock mass which contains many discontinuities. To fill this gap, this research focuses on the brittle–ductile transition stress o...
The recovery of soil void space through infiltration and evapotranspiration processes within green stormwater infrastructure (GSI) is key to continued hydrologic function. As such, soil void space recovery must be well understood to improve the desig...
Ghrelin receptor, a growth hormone secretagogue receptor (GHS-R), is expressed in the pancreas. Emerging evidence indicates that GHS-R is involved in the regulation of glucose-stimulated insulin secretion (GSIS), but the mechanism by which GHS-R regu...
The Geological Strength Index (GSI) is a crucial tool for assessing jointed rock masses, but it is often hindered by subjectivity in visual assessments. In this study, we propose a novel quantitative GSI method wherein 3D laser-scanning point clouds...
Background. NOTCH receptors play a pivotal role in carcinogenesis. Upon ligand binding, a cascade of proteolytic cleavages mediated by ADAM proteases and the γ-secretase complex activates the receptor, ultimately releasing the NOTCH intracellul...
Use of green stormwater infrastructure (GSI) to mitigate urban runoff impacts has grown substantially in recent decades, but municipalities often lack an integrated approach to prioritize areas for implementation, demonstrate compelling evidence of c...
This paper initially provides a practical example on how to estimate a bias-free volumetric fracture count (VFC—fractures/m3) in a tunnel and incorporate it into a new and unified volumetric-based Geological Strength Index (V-GSI) chart. The qu...
On 4 June 2021, short-duration extreme precipitation occurred in Taipei. Within 2 h, over 200 mm of rainfall accumulated in the Xinyi district. In this study, advanced data assimilation technology (e.g., hybrid data and 3D variations) was incorporate...
This paper proposes a novel methodology for very short term forecasting of hourly global solar irradiance (GSI). The proposed methodology is based on meteorology data, especially for optimizing the operation of power generating electricity from photo...
Uterine leiomyosarcoma (uLMS) is a rare and aggressive cancer with few effective therapeutics. The Notch signaling pathway is evolutionarily conserved with oncogenic properties, but it has not been well studied in uLMS. The purpose of our study was t...
Robert K. Logan, Annette Grathoff and I agreed in late summer 2017 to start a research project on the origins of systems thinking. About a year later, we moved the project from the Bertalanffy Center for the Study of Systems Science to the only recen...
This study was performed to obtain information on the sex ratio, spawning period, and size at sexual maturity for fishery management of the largehead hairtail Trichiurus japonicus in Korean waters. The overall sex ratio (female, F; male, M) was 1:0.4...
This study aimed to investigate the effects of perfluorooctanesulfonic acid (PFOS) exposure on glucose-stimulated insulin secretion (GSIS) of rat insulinoma (INS-1) cells and the potential protective effects of procyanidins (PC). The effects of PFOS...
Over the past 30 years, the City of Portland, Oregon, USA, has emerged as a national leader in green stormwater infrastructure (GSI). The initial impetus for implementing sustainable stormwater infrastructure in Portland stemmed from concerns about f...
In people with metabolic syndrome, episodic exposure of pancreatic beta cells to elevated levels of both glucose and free fatty acids (FFAs)—or glucolipotoxicity—can induce a loss of glucose-stimulated insulin secretion (GSIS). This in tu...
The Q-system and Q-slope are empirical methods developed for classifying and assessing rock masses for tunneling, underground mining, and rock slope engineering. Both methods have been used extensively to guide appropriate ground support design for u...
Numerical modeling is increasingly used to analyze practical rock engineering problems. The geological strength index (GSI) is a critical input for many rock engineering problems. However, no available method allows the quantification of GSI input pa...
Limited data are available regarding the effects of elevated coastal artificial light at night (ALAN) on intertidal echinoderms. In this study, we investigated the behavioral, morphological, and physiological responses of the sea urchin (Heliocidaris...
This study examines the microclimate pattern and related spatial perception of urban green stormwater infrastructure (GSI) and the stormwater management landscape, using rain gardens as a case study. It investigates the relationship between different...
Soft magnetic amorphous alloys obtained via rapid quenching techniques are widely employed in different technological fields such as magnetic field detection, bio labeling, non-contact positioning, etc. Among them, magnetoelastic applications stand o...
The generalized Hoek-Brown (GHB) failure criterion can estimate the rock mass parameters required for rock mechanics–related analyses such as numerical modeling in geomechanics. The determination of GHB parameters has been developed in the fiel...
Background/Objectives: Functional assessment of the fetal heart remains a significant challenge in contemporary perinatology due to the absence of a universally accepted gold standard for such evaluations. The aim of this study was to evaluate the re...
Growth hormone secretagogue receptor (GHS-R) is widely known to regulate food intake and adiposity, but its role in glucose homeostasis is unclear. In this study, we investigated the expression of GHS-R in mouse pancreatic islets and its role in glyc...
Glycemic control is a mainstay of type 2 diabetes mellitus (T2DM) clinical management. Despite the continuous improvement in knowledge and progress in terms of treatment, the achievement of the physiologic metabolic profile is still an ongoing challe...
Quantifying time-dependent rock mass degradation is critical for assessing long-term slope stability during open-pit mine closure. This study evaluates the geotechnical evolution of Paleoproterozoic arenites and argillites in the semi-arid Essakane M...
The accurate prediction of coal structure is important to guide the exploration and development of coal reservoirs. Most prediction models are interpreted for a single sensitive coal seam, and the selection of sensitive parameters is correlated with...
Despite the availability of different treatments for type 2 diabetes (T2D), post-diagnosis complications remain prevalent; therefore, more effective treatments are desired. Glucagon-like peptide (GLP)-1-based drugs are currently used for T2D treatmen...
Gait recognition methods based on silhouette templates, such as the Gait Energy Image (GEI), achieve high accuracy under controlled conditions but often degrade when appearance varies due to viewpoint, clothing, or carried objects. In contrast, skele...
The protection of historic buildings in seismic-prone regions is a critical challenge requiring strategies that balance structural safety with cultural preservation. This study proposes an integrated methodological framework for assessing seismic ris...
9 November 2022
The rational spatial allocation of Green Stormwater Infrastructure (GSI), which is an alternative land development approach for managing stormwater close to the source, exerts a crucial effect on coordinating urban development and hydrological sustai...
Effective stormwater management is increasingly vital due to climate change impacts, such as intensified rainfall and flooding. Urban expansion, water scarcity, and intensified agriculture demand innovative solutions like Green Stormwater Infrastruct...
The hypothesis that liver lipid accumulation in fish is an adaptive strategy to survive the winter in the high-altitude environment was assessed in this study. During summer 2019, specimens of Cottus gobio were sampled in 15 watercourses of Friuli Ve...
In this study, the regional Weather Research and Forecasting model (WRF)-based quantitative precipitation forecasts (QPFs) are conducted for an extreme Meiyu rainfall event over East Asia in 2020. The data of water vapor channels 9 and 10 from the Ad...
Urban flooding and the management of stormwater present significant challenges that necessitate innovative and sustainable solutions. This research examines the effectiveness of green stormwater infrastructure (GSI) for resilient storm sewer systems...
The Brazilian Northeast (BNE) is located in the tropical region of Brazil. It is bounded by the Atlantic Ocean, and its climate and vegetation are strongly affected by continental plateaus. The plateaus keep the humid air masses to the east and are r...
This bibliometric review elucidates the emerging intersection of Internet of Things (IoT) technologies and Green Stormwater Infrastructure (GSI), demonstrating the potential to reshape urban stormwater management. The study analyzes a steadily increa...
This study aimed to document the seasonal cycle of steroid levels in the plasma and ovary, including testosterone (T), estradiol-17β (E2) and 17α, 20β-dihydroxy-4-pregnen-3-one (DHP) in relation to ovarian development in wild populations of female bl...
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