New Advances in Anticancer Therapy

A special issue of Cells (ISSN 2073-4409). This special issue belongs to the section "Cellular Pathology".

Deadline for manuscript submissions: 20 October 2025 | Viewed by 485

Special Issue Editor


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Guest Editor
Department of Biochemistry, College of Natural Sciences, Kangwon National University, Chunchon 24341, Republic of Korea
Interests: anti-cancer drug resistance; cancer testis antigen; micro RNAs; exosomes; signaling pathways; allergic inflammation
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Special Issue Information

Dear Colleagues,

Cancer remains one of the leading causes of death worldwide. The existing cancer therapies suffer from severe side effects and drug resistance. Therefore, it is crucial to develop novel therapeutic strategies that can offer more effective and less toxic treatment options for cancer patients. Recent advances in anticancer therapy include RNA vaccines, CAR-T/NK cell therapy, gene editing, immune checkpoint inhibitors, gut microbiome, and antibody-drug conjugates, offering targeted and personalized treatments with improved efficacy and reduced side effects. In this Special Issue of Cells, I invite you to contribute, either in the form of original research articles, reviews, or perspective articles on all aspects related to the theme of “New Advances in Anticancer Therapy”. Expert articles describing functional, biochemical, or general aspects of anticancer therapy are highly welcome. Relevant topics include, but are not limited to:

  • Anticancer drug resistance;
  • Chemoimmunotherapy;
  • Nanotechnology;
  • RNA vaccines;
  • Screening of novel anticancer drugs;
  • Personalized anticancer therapy;
  • Antibody-based immune-stimulating drugs;
  • Combination of epigenetic drugs and immune checkpoint inhibitors.    

Prof. Dr. Dooil Jeoung
Guest Editor

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Keywords

  • antibody-based immunotherapy
  • cell therapy
  • personalized anticancer therapy
  • RNA vaccines
  • nanotechnology

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Published Papers (1 paper)

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Review

58 pages, 5867 KiB  
Review
Carbon Nanotubes as Excellent Adjuvants for Anticancer Therapeutics and Cancer Diagnosis: A Plethora of Laboratory Studies Versus Few Clinical Trials
by Silvana Alfei, Caterina Reggio and Guendalina Zuccari
Cells 2025, 14(14), 1052; https://doi.org/10.3390/cells14141052 - 9 Jul 2025
Viewed by 336
Abstract
Encouraging discoveries and excellent advances in the fight against cancer have led to innovative therapies such as photothermal therapy (PTT), photodynamic therapy (PDT), drug targeting (DT), gene therapy (GT), immunotherapy (IT), and therapies that combine these treatments with conventional chemotherapy (CT). Furthermore, 2,041,910 [...] Read more.
Encouraging discoveries and excellent advances in the fight against cancer have led to innovative therapies such as photothermal therapy (PTT), photodynamic therapy (PDT), drug targeting (DT), gene therapy (GT), immunotherapy (IT), and therapies that combine these treatments with conventional chemotherapy (CT). Furthermore, 2,041,910 new cancer cases and 618,120 cancer deaths have been estimated in the United States for the year 2025. The low survival rate (<50%) and poor prognosis of several cancers, despite aggressive treatments, are due to therapy-induced secondary tumorigenesis and the emergence of drug resistance. Moreover, serious adverse effects and/or great pain usually arise during treatments and/or in survivors, thus lowering the overall effectiveness of these cures. Although prevention is of paramount importance, novel anticancer approaches are urgently needed to address these issues. In the field of anticancer nanomedicine, carbon nanotubes (CNTs) could be of exceptional help due to their intrinsic, unprecedented features, easy functionalization, and large surface area, allowing excellent drug loading. CNTs can serve as drug carriers and as ingredients to engineer multifunctional platforms associated with diverse treatments for both anticancer therapy and diagnosis. The present review debates the most relevant advancements about the adjuvant role that CNTs could have in cancer diagnosis and therapy if associated with PTT, PDT, DT, GT, CT, and IT. Numerous sensing strategies utilising various CNT-based sensors for cancer diagnosis have been discussed in detail, never forgetting the still not fully clarified toxicological aspects that may derive from their extensive use. The unsolved challenges that still hamper the possible translation of CNT-based material in clinics, including regulatory hurdles, have been discussed to push scientists to focus on the development of advanced synthetic and purification work-up procedures, thus achieving more perfect CNTs for their safer real-life clinical use. Full article
(This article belongs to the Special Issue New Advances in Anticancer Therapy)
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